|
|
lignoceroyl-CoA + H2O <=> CoA + n-tetracosanoic_acid
|
3.1.2
3.1.2.2
palmitoyl-CoA hydrolase
|
–
–
|
| |
KEGG:
R08185
SABIO-RK:
6587
|
|
|
|
eicosenoyl-CoA + 2 ferricytochrome_b5 + O2 + 2 H+ <=> (8Z,11Z)-Icosadienoyl-CoA + 2 ferricytochrome_b5 + 2 H2O
|
1.14.19.3
acyl-CoA 6-desaturase
|
–
|
| |
KEGG:
R12168
|
|
|
|
(4Z,7Z,10Z,13Z,16Z)-Docosapentaenoyl-CoA + acetyl-CoA <=> (6Z,9Z,12Z,15Z,18Z)-3-Oxotetracosapentaenoyl-CoA + CoA
|
2.3.1.16
acetyl-CoA C-acyltransferase
2.3.1.176
propanoyl-CoA C-acyltransferase
|
–
–
|
| |
KEGG:
R07953
MetaCyc:
RXN-17116
|
|
|
|
arachidoyl-CoA + H2O <=> eicosanoic_acid + CoA + H+
|
3.1.2.2
palmitoyl-CoA hydrolase
3.1.2.20
acyl-CoA hydrolase
|
–
–
|
| |
BRENDA:
BS360751
KEGG:
R08175
MetaCyc:
RXN-9629
SABIO-RK:
6594
|
|
|
|
docosahexaenoyl-CoA + H2O <=> docosahexaenoic_acid + CoA + H+
|
3.1.2.2
palmitoyl-CoA hydrolase
3.1.2.20
acyl-CoA hydrolase
|
–
–
|
| |
BRENDA:
BS360760
KEGG:
R08180
MetaCyc:
RXN-16063
|
|
|
|
(9Z,12Z,15Z,18Z)-Tetracosatetraenoyl-CoA + O2 + ferricytochrome_b5 + H+ <=> (6Z,9Z,12Z,15Z,18Z)-Tetracosapentaenoyl-CoA + H2O + ferricytochrome_b5
|
1.14.19.3
acyl-CoA 6-desaturase
|
–
|
| |
KEGG:
R11111
MetaCyc:
RXN-17112
|
|
|
|
linoleoyl-CoA + H2O <=> H+ + linoleic_acid + CoA
|
3.1.2
3.1.2.2
palmitoyl-CoA hydrolase
3.1.2.20
acyl-CoA hydrolase
|
–
–
–
|
| |
BRENDA:
BS360756
KEGG:
R08177
MetaCyc:
LINOLEOYL-RXN
SABIO-RK:
6586
|
|
|
|
(6Z,9Z,12Z,15Z,18Z)-Tetracosapentaenoyl-CoA + O2 <=> (2E,6Z,9Z,12Z,15Z,18Z)-Tetracosahexaenoyl-CoA + H2O2
|
1.3.3.6
acyl-CoA oxidase
|
–
|
| |
KEGG:
R07950
MetaCyc:
RXN-17113
|
|
|
|
(11Z,14Z,17Z)-icosa-11,14,17-trienoyl-CoA + H2O <=> 11,14,17-Eicosatrienoic_acid + CoA + H+
|
3.1.2
|
–
|
| |
KEGG:
R08192
MetaCyc:
RXN-12998
|
|
|
|
(11Z,14Z,17Z)-icosa-11,14,17-trienoyl-CoA + O2 + ferricytochrome_b5 + H+ <=> (8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-CoA + H2O + ferricytochrome_b5
|
1.14.19
1.14.19.3
acyl-CoA 6-desaturase
|
–
–
|
| |
KEGG:
R12170
MetaCyc:
RXN-17106
|
|
|
|
erucoyl-CoA + H2O <=> CoA + erucic_acid
|
3.1.2
|
–
|
| |
KEGG:
R08187
|
|
|
|
oleoyl-CoA + 2 ferricytochrome_b5 + O2 + 2 H+ <=> (6Z,9Z)-Octadecadienoyl-CoA + 2 ferricytochrome_b5 + 2 H2O
|
1.14.19.3
acyl-CoA 6-desaturase
|
–
|
| |
KEGG:
R12167
|
|
|
|
docosahexaenoyl-CoA + acetyl-CoA <=> (6Z,9Z,12Z,15Z,18Z,21Z)-3-Oxotetracosahexaenoyl-CoA + CoA
|
2.3.1.16
acetyl-CoA C-acyltransferase
2.3.1.176
propanoyl-CoA C-acyltransferase
|
–
–
|
| |
KEGG:
R07937
MetaCyc:
RXN-16137
|
|
|
|
oleoyl-CoA + H2O <=> H+ + oleic_acid + CoA
|
2.3.1.9
acetyl-CoA C-acetyltransferase
3.1.1.1
carboxylesterase
3.1.2.1
acetyl-CoA hydrolase
3.1.2.2
palmitoyl-CoA hydrolase
3.1.2.20
acyl-CoA hydrolase
3.1.2.22
palmitoyl[protein] hydrolase
|
–
–
–
–
–
–
|
| |
BRENDA:
BS115467
KEGG:
R08176
MetaCyc:
RXN-9666
SABIO-RK:
6580
|
|
|
|
linoleoyl-CoA + O2 + ferricytochrome_b5 + H+ <=> linolenoyl-CoA + H2O + ferricytochrome_b5
|
1.14.19
1.14.19.13
acyl-CoA 15-desaturase
|
–
–
|
| |
KEGG:
R12205
MetaCyc:
RXN-16228
|
|
|
|
(6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosahexaenoyl-CoA + O2 <=> (2E,6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosaheptaenoyl-CoA + H2O2
|
1.3.3.6
acyl-CoA oxidase
|
–
|
| |
KEGG:
R07934
MetaCyc:
RXN-16134
|
|
|
|
oleoyl-CoA + ferricytochrome_b5 + O2 + H+ <=> linoleoyl-CoA + ferricytochrome_b5 + H2O
|
1.14.19.22
acyl-lipid omega-6 desaturase (cytochrome b5)
1.14.19.6
acyl-CoA (9+3)-desaturase
|
–
–
|
| |
BRENDA:
BR48583
KEGG:
R11043
MetaCyc:
RXN-9601
|
|
|
|
malonyl-CoA + palmitoyl-CoA + H+ <=> 3-oxostearoyl-CoA + CO2 + CoA
|
2.3.1.199
very-long-chain 3-oxoacyl-CoA synthase
|
–
|
| |
BRENDA:
BS435705
KEGG:
R07758
MetaCyc:
RXN-9543
|
|
|
|
palmitoyl-CoA + H2O <=> H+ + palmitate + CoA
|
2.3.1.16
acetyl-CoA C-acyltransferase
3.1.1.1
carboxylesterase
3.1.1.23
acylglycerol lipase
3.1.1.5
lysophospholipase
3.1.2
3.1.2.1
acetyl-CoA hydrolase
3.1.2.2
palmitoyl-CoA hydrolase
3.1.2.20
acyl-CoA hydrolase
3.1.2.22
palmitoyl[protein] hydrolase
3.1.2.25
phenylacetyl-CoA hydrolase
|
–
–
–
–
–
–
–
–
–
–
|
| |
BRENDA:
BR48147;
BS115468
KEGG:
R01274;
R08174;
R09450
MetaCyc:
PALMITOYL-COA-HYDROLASE-RXN;
RXN-16395;
RXN-9624
SABIO-RK:
1490;
6573
|
|
|
|
8,11,14-eicosatrienoic_acid + O2 + ferricytochrome_b5 + H+ <=> Arachidonoyl-CoA + H2O + ferricytochrome_b5
|
1.14.19.44
acyl-CoA (8-3)-desaturase
|
–
|
| |
BRENDA:
BR51508;
BS433635
KEGG:
R11059
MetaCyc:
RXN-16064
|
|
|
|
linoleoyl-CoA + O2 + ferricytochrome_b5 + H+ <=> gamma-linolenoyl-CoA + H2O + ferricytochrome_b5
|
1.14.19.3
acyl-CoA 6-desaturase
|
–
|
| |
BRENDA:
BR40397
KEGG:
R03814
MetaCyc:
1.14.19.3-RXN
|
|
|
|
(11Z,14Z)-icosa-11,14-dienoyl-CoA + H2O <=> CoA + eicosadienoic_acid
|
3.1.2
|
–
|
| |
KEGG:
R08190
|
|
|
|
behenoyl-CoA + H2O <=> CoA + behenic_acid
|
3.1.2
3.1.2.2
palmitoyl-CoA hydrolase
|
–
–
|
| |
KEGG:
R08184
SABIO-RK:
6600
|
|
|
|
stearoyl-CoA + NADPH + O2 + H+ <=> oleoyl-CoA + NADP+ + H2O
|
1.14.19
1.14.19.1
stearoyl-CoA 9-desaturase
1.14.19.M26
|
–
–
–
|
| |
BRENDA:
BS287600
KEGG:
R12048
MetaCyc:
RXN-20779
|
|
|
|
3-hydroxystearoyl-CoA <=> trans-2-octadecenoyl-CoA + H2O
|
4.2.1.119
enoyl-CoA hydratase 2
4.2.1.134
very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase
|
–
–
|
| |
KEGG:
R07760
MetaCyc:
RXN-9545
|
|
|
|
(3R,6Z,9Z,12Z,15Z,18Z,21Z)-3-Hydroxytetracosahexaenoyl-CoA <=> (2E,6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosaheptaenoyl-CoA + H2O
|
4.2.1.119
enoyl-CoA hydratase 2
|
–
|
| |
KEGG:
R07935
|
|
|
|
(13Z,16Z)-Docosadienoyl-CoA + H2O <=> CoA + (13Z,16Z)-Docosadienoic_acid
|
3.1.2
|
–
|
| |
KEGG:
R08273
|
|
|
|
stearoyl-CoA + ferricytochrome_b5 + O2 + H+ <=> oleoyl-CoA + ferricytochrome_b5 + H2O
|
1.14.19.1
stearoyl-CoA 9-desaturase
|
–
|
| |
BRENDA:
BR40342
KEGG:
R02222
MetaCyc:
1.14.19.1-RXN
|
|
|
|
(3R,6Z,9Z,12Z,15Z,18Z)-3-Hydroxytetracosapentaenoyl-CoA <=> (2E,6Z,9Z,12Z,15Z,18Z)-Tetracosahexaenoyl-CoA + H2O
|
4.2.1.119
enoyl-CoA hydratase 2
|
–
|
| |
KEGG:
R07951
|
|
|
|
3-hydroxystearoyl-CoA + NADP+ <=> 3-oxostearoyl-CoA + NADPH + H+
|
1.1.1
1.1.1.330
very-long-chain 3-oxoacyl-CoA reductase
|
–
–
|
| |
BRENDA:
BS420006
KEGG:
R07759
MetaCyc:
RXN-9544
|
|
|
|
eicosapentaenoyl-CoA + H2O <=> eicosapentaenoic_acid + CoA + H+
|
3.1.2.2
palmitoyl-CoA hydrolase
3.1.2.20
acyl-CoA hydrolase
|
–
–
|
| |
BRENDA:
BS360759
KEGG:
R08179
MetaCyc:
RXN-13430
|
|
|
|
Arachidonoyl-CoA + H2O <=> CoA + arachidonic_acid
|
3.1.2.2
palmitoyl-CoA hydrolase
3.1.2.20
acyl-CoA hydrolase
3.1.2.25
phenylacetyl-CoA hydrolase
|
–
–
–
|
| |
BRENDA:
BS360750
KEGG:
R08183
SABIO-RK:
6601
|
|
|
|
linolenoyl-CoA + O2 + ferricytochrome_b5 + H+ <=> stearidonoyl-CoA + H2O + ferricytochrome_b5
|
1.14.19.3
acyl-CoA 6-desaturase
|
–
|
| |
BRENDA:
BR51360
KEGG:
R07933
MetaCyc:
RXN-13426
|
|
|
|
stearoyl-CoA + NADP+ <=> trans-2-octadecenoyl-CoA + NADPH + H+
|
1.3.1
1.3.1.93
very-long-chain enoyl-CoA reductase
|
–
–
|
| |
KEGG:
R07761
MetaCyc:
RXN-9546
|
|
|
|
(7Z,10Z,13Z,16Z)-Docosatetraenoyl-CoA + H2O <=> CoA + cis-7,10,13,16-docosatetraenoic_acid
|
3.1.2
|
–
|
| |
KEGG:
R08191
|
|
|
|
(15Z)-tetracosenoyl-CoA + H2O <=> CoA + nervonic_acid
|
3.1.2
|
–
|
| |
KEGG:
R08188
|
|
|
|
(9Z,12Z,15Z,18Z,21Z)-Tetracosapentaenoyl-CoA + O2 + ferricytochrome_b5 + H+ <=> (6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosahexaenoyl-CoA + H2O + ferricytochrome_b5
|
1.14.19.3
acyl-CoA 6-desaturase
|
–
|
| |
KEGG:
R11110
MetaCyc:
RXN-16132
|
|
|
|
(3R,6Z,9Z,12Z,15Z,18Z,21Z)-3-Hydroxytetracosahexaenoyl-CoA + NAD+ <=> (6Z,9Z,12Z,15Z,18Z,21Z)-3-Oxotetracosahexaenoyl-CoA + NADH + H+
|
1.1.1
|
–
|
| |
KEGG:
R07936
|
|
|
|
palmitoyl-CoA + O2 + ferricytochrome_b5 + H+ <=> Sapienoyl-CoA + H2O + ferricytochrome_b5
|
1.14.19.3
acyl-CoA 6-desaturase
|
–
|
| |
KEGG:
R12172
MetaCyc:
RXN-16065
|
|
|
|
palmitoyl-CoA + ferricytochrome_b5 + O2 + H+ <=> palmitoleoyl-CoA + ferricytochrome_b5 + H2O
|
1.14.19.1
stearoyl-CoA 9-desaturase
|
–
|
| |
BRENDA:
BS394945
KEGG:
R12173
MetaCyc:
RXN-10664
|
|
|
|
docosapentaenoyl-CoA + H2O <=> docosapentaenoic_acid + CoA + H+
|
3.1.2
|
–
|
| |
KEGG:
R08189
MetaCyc:
RXN-13446
|
|
|
|
(8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-CoA + O2 + ferricytochrome_b5 + H+ <=> eicosapentaenoyl-CoA + H2O + ferricytochrome_b5
|
1.14.19.44
acyl-CoA (8-3)-desaturase
|
–
|
| |
BRENDA:
BR51509
KEGG:
R11060
MetaCyc:
RXN-13429
|
|
|
|
(11Z,14Z)-icosa-11,14-dienoyl-CoA + O2 + ferricytochrome_b5 + H+ <=> 8,11,14-eicosatrienoic_acid + H2O + ferricytochrome_b5
|
1.14.19
1.14.19.3
acyl-CoA 6-desaturase
|
–
–
|
| |
KEGG:
R12171
MetaCyc:
RXN-17105
|
|
|
|
(3R,6Z,9Z,12Z,15Z,18Z)-3-Hydroxytetracosapentaenoyl-CoA + NAD+ <=> (6Z,9Z,12Z,15Z,18Z)-3-Oxotetracosapentaenoyl-CoA + NADH + H+
|
1.1.1
|
–
|
| |
KEGG:
R07952
|
|
|
|
linolenoyl-CoA + H2O <=> CoA + linolenic_acid
|
3.1.2.2
palmitoyl-CoA hydrolase
3.1.2.20
acyl-CoA hydrolase
|
–
–
|
| |
BRENDA:
BS360757
KEGG:
R08178
SABIO-RK:
13583
|
|
|
|
stearoyl-[acyl-carrier_protein] + reduced_ferredoxin_[iron-sulfur]_cluster + O2 + H+ <=> oleoyl-[acyl-carrier_protein] + oxidized_ferredoxin + H2O
|
1.14.19.2
stearoyl-[acyl-carrier-protein] 9-desaturase
|
–
|
| |
BRENDA:
BR40398;
BS453858
KEGG:
R03370
MetaCyc:
RXN-7903
SABIO-RK:
10485
|
|
|
|
palmitoyl-CoA + H2O <=> H+ + palmitate + CoA
|
2.3.1.16
acetyl-CoA C-acyltransferase
3.1.1.1
carboxylesterase
3.1.1.23
acylglycerol lipase
3.1.1.5
lysophospholipase
3.1.2
3.1.2.1
acetyl-CoA hydrolase
3.1.2.2
palmitoyl-CoA hydrolase
3.1.2.20
acyl-CoA hydrolase
3.1.2.22
palmitoyl[protein] hydrolase
3.1.2.25
phenylacetyl-CoA hydrolase
|
–
–
–
–
–
–
–
–
–
–
|
| |
BRENDA:
BR48147;
BS115468
KEGG:
R01274;
R08174;
R09450
MetaCyc:
PALMITOYL-COA-HYDROLASE-RXN;
RXN-16395;
RXN-9624
SABIO-RK:
1490;
6573
|
|
|
|
8,11,14-eicosatrienoic_acid + H2O <=> 8,11,14-eicosatrienoic_acid + CoA + H+
|
3.1.2.2
palmitoyl-CoA hydrolase
|
–
|
| |
KEGG:
R08182
MetaCyc:
RXN-13435
|
|
|
|
(8Z,11Z)-Icosadienoyl-CoA + 2 ferricytochrome_b5 + O2 + 2 H+ <=> 5,8,11-eicosatrienoyl-CoA + 2 ferricytochrome_b5 + 2 H2O
|
1.14.19.44
acyl-CoA (8-3)-desaturase
|
–
|
| |
KEGG:
R12169
|
|
|
|
gamma-linolenoyl-CoA + H2O <=> CoA + gamma-linolenic_acid
|
3.1.2.2
palmitoyl-CoA hydrolase
3.1.2.20
acyl-CoA hydrolase
|
–
–
|
| |
BRENDA:
BS360758
KEGG:
R08181
|
|
|
|
eicosenoyl-CoA + H2O <=> CoA + 11-eicosenoic_acid
|
3.1.2
|
–
|
| |
KEGG:
R08186
|
|
