|
|
Hydroxyspheroidene + 2 O2 + 4 reduced_ferredoxin + 4 H+ <=> Hydroxyspheroidenone + 3 H2O + 4 oxidized_ferredoxin
|
1.14.15.9
spheroidene monooxygenase
|
–
|
|
KEGG:
R07538
|
|
|
|
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> 6-Methylsalicylate + CoA + CO2 + NADP+ + H2O
|
2.3.1.165
6-methylsalicylic-acid synthase
|
–
|
|
BRENDA:
BR44013
KEGG:
R07253
MetaCyc:
2.3.1.165-RXN
|
|
|
|
Carbamoyl_phosphate + kanamycin_B + ATP + H2O <=> 6''''-O-carbamoylkanamycin_B + AMP + diphosphate + phosphate + H+
|
6.1.2.2
nebramycin 5' synthase
|
–
|
|
KEGG:
R11279
MetaCyc:
RXN-15287
|
|
|
|
S-adenosyl-L-methionine + 5-hydroxyferulic_acid <=> H+ + Sinapic_acid + S-adenosyl-L-homocysteine
|
2.1.1.104
caffeoyl-CoA O-methyltransferase
2.1.1.42
flavone 3'-O-methyltransferase
2.1.1.68
caffeate O-methyltransferase
|
–
–
–
|
|
BRENDA:
BS319577
KEGG:
R02379
MetaCyc:
RXN-3422
|
|
|
|
3-Hydroxy-6,7,8-trimethoxy-2-naphthoate <=> 3-Hydroxy-7,8-dimethoxy-6-isopropoxy-2-naphthoate
|
not assigned
|
–
|
|
KEGG:
R11389
|
|
|
|
1-epi-Valienol_1-phosphate + NTP <=> NDP-1-epi-valienol + diphosphate
|
2.7.7.91
valienol-1-phosphate guanylyltransferase
|
–
|
|
KEGG:
R11237
|
|
|
|
S-adenosyl-L-methionine + 8-demethyl-8-(2,3,4-O-trimethyl-alpha-L-rhamnosyl)-tetracenomycin_C <=> elloramycin + S-adenosyl-L-homocysteine + H+
|
2.1.1
|
–
|
|
KEGG:
R10959
MetaCyc:
RXN-15402
|
|
|
|
Roquefortine_D <=> Roquefortine_C
|
1
|
–
|
|
KEGG:
R12440
|
|
|
|
5-Hydroxy-1-(4-hydroxyphenyl)-3-decanone <=> 1-(3,4-Dihydroxyphenyl)-5-hydroxy-3-decanone
|
not assigned
|
–
|
|
KEGG:
R08802
|
|
|
|
6,8a-Seco-6,8a-deoxy-5-oxoavermectin_''''1a''''_aglycone + NADPH + O2 <=> 5-Oxoavermectin_''''1a''''_aglycone + NADP+ + H2O
|
1.14
|
–
|
|
KEGG:
R06467
|
|
|
|
catechin + NADP+ + H2O <=> Leucocyanidin + NADPH + H+
|
1.17.1.3
leucoanthocyanidin reductase
|
–
|
|
BRENDA:
BR47371
KEGG:
R06532
MetaCyc:
RXN-1484
|
|
|
|
S-adenosyl-L-methionine + aklanonate <=> S-adenosyl-L-homocysteine + methyl_aklanonate
|
2.1.1.288
aklanonic acid methyltransferase
|
–
|
|
BRENDA:
BR50636
KEGG:
R06680
MetaCyc:
RXN-14831
|
|
|
|
UDP-N-acetyl-D-glucosamine + ribostamycin <=> 2''''''-acetyl-6''''''-deamino-6''''''-hydroxyneomycin_C + UDP + H+
|
2.4.1.285
UDP-GlcNAc:ribostamycin N-acetylglucosaminyltransferase
|
–
|
|
BRENDA:
BR50181
KEGG:
R08900
MetaCyc:
RXN-13176
|
|
|
|
Sinapic_acid + CoA + ATP <=> sinapoyl-CoA + AMP + diphosphate
|
6.2.1.12
4-coumarate---CoA ligase
|
–
|
|
BRENDA:
BS368951
KEGG:
R02221
MetaCyc:
RXN-10919
SABIO-RK:
2193
|
|
|
|
4-coumaraldehyde <=> caffeoyl_aldehyde
|
1.14.13
|
–
|
|
KEGG:
R06579
|
|
|
|
beta-Hydroxy-L-tyrosyl-[pcp] <=> beta-Keto-L-tyrosyl-[pcp]
|
not assigned
|
–
|
|
KEGG:
R06753
|
|
|
|
Tabtoxin + H2O <=> Tabtoxinine-beta-lactam + L-threonine
|
3.4
3.4.11
|
–
–
|
|
KEGG:
R10891
MetaCyc:
RXN-19255
|
|
|
|
(S)-beta-Tyrosyl-[pcp] + FADH2 + Cl- + O2 + H+ <=> (S)-3-Chloro-beta-tyrosyl-[pcp] + FAD + 2 H2O
|
1.14.19
|
–
|
|
KEGG:
R11368
|
|
|
|
glycine + 2-oxoglutarate <=> glyoxylate + L-glutamate
|
2.6.1.2
alanine transaminase
2.6.1.4
glycine transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.44
alanine---glyoxylate transaminase
2.6.1.48
5-aminovalerate transaminase
2.6.1.60
aromatic-amino-acid---glyoxylate transaminase
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
–
–
–
–
–
–
|
|
BRENDA:
BR47690
KEGG:
R00372
MetaCyc:
GLYCINE-AMINOTRANSFERASE-RXN
SABIO-RK:
839
|
|
|
|
D-erythrose_4-phosphate + D-xylulose_5-phosphate <=> beta-D-fructose_6-phosphate + D-glyceraldehyde_3-phosphate
|
2.2.1.1
transketolase
2.2.1.3
formaldehyde transketolase
|
–
–
|
|
BRENDA:
BS320170;
BS320221;
BS434641
KEGG:
R01067;
R01830
MetaCyc:
2TRANSKETO-RXN
SABIO-RK:
1337
|
|
|
|
Premithramycin_A3 + dTDP-D-boivinose <=> 3A-Deolivosylpremithramycin_B + dTDP + H+
|
2.4.1
|
–
|
|
KEGG:
R09351
MetaCyc:
RXN-13380
|
|
|
|
UDP-glucose + alpha-D-glucose_6-phosphate <=> UDP + alpha,alpha''-Trehalose_6-phosphate
|
2.4.1.15
alpha,alpha-trehalose-phosphate synthase (UDP-forming)
|
–
|
|
KEGG:
R02737
|
|
|
|
L-tryptophan + FADH2 + Cl- + O2 <=> 7-chloro-L-tryptophan + FAD + H2O
|
1.14.19.9
tryptophan 7-halogenase
|
–
|
|
BRENDA:
BR48866
KEGG:
R09570
MetaCyc:
RXN-10842
SABIO-RK:
14708
|
|
|
|
4-coumaroyl-CoA + NADPH + H+ <=> 4-coumaraldehyde + CoA + NADP+
|
1.2.1.44
cinnamoyl-CoA reductase
|
–
|
|
BRENDA:
BS189225;
BS388396
KEGG:
R01615
MetaCyc:
RXN-1101
SABIO-RK:
1760
|
|
|
|
5,10-Dihydrophenazine + O2 <=> phenazine + H2O2
|
not assigned
|
–
|
|
KEGG:
R11573
MetaCyc:
RXN-17696
|
|
|
|
OPC6-CoA + FAD <=> trans-2-Enoyl-OPC6-CoA + FADH2
|
1.3.3.6
acyl-CoA oxidase
|
–
|
|
KEGG:
R07892
|
|
|
|
gibberellin_A51 <=> Gibberellin_A51-catabolite
|
1.14.11.13
gibberellin 2beta-dioxygenase
|
–
|
|
KEGG:
R06343
|
|
|
|
Terpendole_G <=> Terpendole_B
|
not assigned
|
–
|
|
KEGG:
R10406
|
|
|
|
geranylgeranyl_diphosphate <=> fusicocca-2,10(14)-diene + diphosphate
|
4.2.3.43
fusicocca-2,10(14)-diene synthase
|
–
|
|
BRENDA:
BR49050
KEGG:
R09123
MetaCyc:
RXN-10632
|
|
|
|
delta-tocotrienol <=> 6-geranylgeranyl-2-methylbenzene-1,4-diol
|
5.5.1.24
tocopherol cyclase
|
–
|
|
BRENDA:
BR50793
KEGG:
R10623
MetaCyc:
RXN-14921
|
|
|
|
chlorogenic_acid + CoA <=> caffeoyl-CoA + quinate
|
2.3.1
2.3.1.133
shikimate O-hydroxycinnamoyltransferase
2.3.1.99
quinate O-hydroxycinnamoyltransferase
|
–
–
–
|
|
BRENDA:
BS321558
KEGG:
R01945
MetaCyc:
RXN-2622
|
|
|
|
9-cis-violaxanthin <=> 9''-cis-Neoxanthin
|
5.3.99.9
neoxanthin synthase
|
–
|
|
KEGG:
R06951
|
|
|
|
oxaloacetate + ITP <=> CO2 + phosphoenolpyruvate + IDP
|
4.1.1.32
phosphoenolpyruvate carboxykinase (GTP)
4.1.1.49
phosphoenolpyruvate carboxykinase (ATP)
|
–
–
|
|
BRENDA:
BS1402
KEGG:
R00726
MetaCyc:
RXN-12481
SABIO-RK:
583
|
|
|
|
H+ + (-)-tetrahydropalmatine + O2 <=> palmatine + H2O2
|
1.21.3.3
reticuline oxidase
1.3.3.8
tetrahydroberberine oxidase
|
–
–
|
|
BRENDA:
BS442681
KEGG:
R08795
MetaCyc:
RXN-8699
|
|
|
|
dTDP-4-amino-2,4-dideoxy-beta-L-xylose + 2-oxoglutarate <=> dTDP-4-oxo-2-deoxy-beta-L-xylose + L-glutamate
|
2.6.1
|
–
|
|
KEGG:
R11475
|
|
|
|
(R)-Hemiketal <=> (R)-DNPA + H2O
|
not assigned
|
–
|
|
KEGG:
R09311
|
|
|
|
dTDP-4-oxo-2,6-dideoxy-D-allose <=> dTDP-4-oxo-2,6-dideoxy-L-mannose
|
5.1.3
|
–
|
|
KEGG:
R06433
|
|
|
|
2-epi-5-epi-valiolone <=> 5-epi-valiolone
|
5.1.3.33
2-epi-5-epi-valiolone epimerase
|
–
|
|
BRENDA:
BR51250
KEGG:
R11079
MetaCyc:
RXN-9141
|
|
|
|
ent-cassa-12,15-diene + 3 reduced_flavodoxin + 3 O2 <=> ent-3beta-hydroxycassa-12,15-dien-2-one + 3 flavin + 4 H2O
|
1.14.14.69
ent-cassadiene hydroxylase
|
–
|
|
BRENDA:
BR52301
KEGG:
R11981
|
|
|
|
D-ribose_5-phosphate <=> D-ribulose_5-phosphate
|
5.3.1.6
ribose-5-phosphate isomerase
|
–
|
|
BRENDA:
BR237
KEGG:
R01056
MetaCyc:
RIB5PISOM-RXN
|
|
|
|
bilirubin + coenzyme_F420-1 <=> Biliverdin + Reduced_coenzyme_F420-(gamma-Glu)n
|
1.3.98
|
–
|
|
KEGG:
R12481
|
|
|
|
H+ + 6,7-dimethyl-8-(1'-D-ribityl)lumazine <=> 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione + riboflavin
|
2.5.1.9
riboflavin synthase
|
–
|
|
BRENDA:
BR47473
KEGG:
R00066
MetaCyc:
RIBOFLAVIN-SYN-RXN
SABIO-RK:
653
|
|
|
|
campesterol <=> Campest-4-en-3beta-ol
|
5.3.3.1
steroid Delta-isomerase
|
–
|
|
KEGG:
R07427
MetaCyc:
RXN-709
|
|
|
|
(S)-reticuline + reduced_flavodoxin + O2 <=> (S)-corytuberine + flavin + 2 H2O
|
1.14.19.51
(S)-corytuberine synthase
|
–
|
|
BRENDA:
BR52042
KEGG:
R08790
|
|
|
|
ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate <=> H+ + ADP + phosphate + 5''-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole
|
6.3.2.6
phosphoribosylaminoimidazolesuccinocarboxamide synthase
|
–
|
|
BRENDA:
BR122
KEGG:
R04591
MetaCyc:
SAICARSYN-RXN
|
|
|
|
Aquayamycin + dTDP-L-rhodinose <=> 100-2 + dTDP
|
not assigned
|
–
|
|
KEGG:
R06666
|
|
|
|
10-deoxymethymycin + O2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> methymycin + oxidized_ferredoxin + H2O
|
1.14.15.33
pikromycin synthase
|
–
|
|
BRENDA:
BR50920
KEGG:
R06463
MetaCyc:
RXN-15100
|
|
|
|
S-(Hydroxyphenylacetothiohydroximoyl)-L-cysteine + H2O <=> p-Hydroxyphenylacetothiohydroximate + pyruvate + NH3 + H+
|
4.4.1
4.4.1.13
cysteine-S-conjugate beta-lyase
|
–
–
|
|
KEGG:
R08660
MetaCyc:
RXN-19596
|
|
|
|
dihydrozeatin_riboside + H2O <=> dihydrozeatin + D-ribose
|
not assigned
|
–
|
|
KEGG:
R08074
|
|
|
|
ent-kaur-16-en-19-oate + reduced_flavodoxin + O2 <=> ent-7alpha-hydroxykaur-16-en-19-oate + flavin + H2O
|
1.14.14.107
ent-kaurenoic acid monooxygenase
|
–
|
|
BRENDA:
BR40543
KEGG:
R06294
|
|
|
|
neoabietadiene <=> Neoabietinol
|
1.14.13
|
–
|
|
KEGG:
R06353
|
|
|
|
4 2-imino-3-(7-chloroindol-3-yl)propanoate + O2 <=> 2 dichlorochromopyrrolate + 2 NH3 + 2 H2O
|
1.21.98.2
dichlorochromopyrrolate synthase
|
–
|
|
BRENDA:
BS402313
KEGG:
R09566
|
|
|
|
heme + O2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> Biliverdin + Fe2+ + CO + oxidized_ferredoxin + H2O
|
1.14.15.20
heme oxygenase (biliverdin-producing, ferredoxin)
|
–
|
|
BRENDA:
BR51703
KEGG:
R11579
MetaCyc:
RXN-17523
|
|
|
|
DELTA1-piperideine + trans-cinnamate + benzoyl-CoA <=> Lobelanine + CoA
|
not assigned
|
–
|
|
KEGG:
R08423
|
|
|
|
sitosterol + NADPH + H+ + O2 <=> stigmasterol + NADP+ + H2O
|
1.14.19.41
sterol 22-desaturase
|
–
|
|
BRENDA:
BS432714
KEGG:
R07489
|
|
|
|
N-Methylpelletierine <=> Pseudopelletierine
|
not assigned
|
–
|
|
KEGG:
R08425
|
|
|
|
Rifamycin_W <=> Rifamycin_W-hemiacetal
|
not assigned
|
–
|
|
KEGG:
R06992
|
|
|
|
beta-D-glucose_6-phosphate <=> beta-D-fructose_6-phosphate
|
5.3.1.9
glucose-6-phosphate isomerase
|
–
|
|
KEGG:
R03321
|
|
|
|
crocetin_dialdehyde <=> crocetin
|
not assigned
|
–
|
|
KEGG:
R12135
|
|
|
|
paromamine + O2 <=> 6''-dehydroparomamine + H2O2
|
1.1.3.43
paromamine 6'-oxidase
|
–
|
|
BRENDA:
BR50143
KEGG:
R08896
MetaCyc:
RXN-13165
|
|
|
|
Fumiquinazoline_F + 3 reduced_flavodoxin + 2 O2 <=> Fumiquinazoline_F-indoline-2'',3''-diol + 3 flavin + 2 H2O
|
1.14.14
|
–
|
|
KEGG:
R12418
|
|
|
|
UDP-alpha-D-kanosamine <=> kanosamine
|
not assigned
|
–
|
|
KEGG:
R06587
|
|
|
|
strictosidine <=> Strychnine
|
not assigned
|
–
|
|
KEGG:
R08495
|
|
|
|
cocaine + H2O <=> H+ + methyl_ecgonine + benzoate
|
3.1.1.1
carboxylesterase
3.1.1.8
cholinesterase
3.1.1.84
cocaine esterase
|
–
–
–
|
|
BRENDA:
BR49194;
BS402273
KEGG:
R06728
MetaCyc:
RXN-11192
|
|
|
|
UDP-glucose + beta-D-fructose_6-phosphate <=> sucrose_6F-phosphate + UDP + H+
|
2.4.1.13
sucrose synthase
2.4.1.14
sucrose-phosphate synthase
|
–
–
|
|
BRENDA:
BR47559;
BS355460
KEGG:
R00766;
R06073
MetaCyc:
SUCROSE-PHOSPHATE-SYNTHASE-RXN
SABIO-RK:
8678
|
|
|
|
Terpendole_E + 4 NADPH + 4 O2 + 4 H+ <=> 13-Desoxyterpendole_I + formate + 4 NADP+ + 5 H2O
|
1.14.13
|
–
|
|
KEGG:
R10376
|
|
|
|
5-methyl-3-oxo-4-hexenoyl-CoA + CoA <=> 3-methylcrotonoyl-CoA + acetyl-CoA
|
2.3.1
2.3.1.16
acetyl-CoA C-acyltransferase
|
–
–
|
|
BRENDA:
BS417867
KEGG:
R08095
MetaCyc:
RXN-11921
|
|
|
|
ATP + psilocin <=> ADP + psilocybin + H+
|
2.7.1.222
4-hydroxytryptamine kinase
|
–
|
|
BRENDA:
BS442314
KEGG:
R08480
MetaCyc:
RXN-19125
|
|
|
|
4''-O-Desmethyl-3-O-acetylpapaveroxine + H2O <=> 4''-O-Desmethylpapaveroxine + acetate
|
3.1.1.105
3-O-acetylpapaveroxine carboxylesterase
|
–
|
|
KEGG:
R11694
|
|
|
|
H+ + sulfate + ATP <=> adenosine_5''-phosphosulfate + diphosphate
|
2.7.7.4
sulfate adenylyltransferase
|
–
|
|
BRENDA:
BR47884
KEGG:
R00529
MetaCyc:
SULFATE-ADENYLYLTRANS-RXN
SABIO-RK:
947
|
|
|
|
beta-PC-M6 + O2 + NADPH + H+ <=> 13-Desoxypaxilline + NADP+ + 2 H2O
|
1.14.13
|
–
|
|
KEGG:
R10358
|
|
|
|
NDP-2-amino-4-oxo-2,6-dideoxy-D-galactose <=> NDP-2-amino-2,6-dideoxy-D-galactose
|
not assigned
|
–
|
|
KEGG:
R11433
|
|
|
|
1-amino-1-deoxy-scyllo-inositol + ATP <=> H+ + 1-amino-1-deoxy-scyllo-inositol_4-phosphate + ADP
|
2.7.1.65
scyllo-inosamine 4-kinase
|
–
|
|
BRENDA:
BR47386
KEGG:
R03384
MetaCyc:
SCYLLO-INOSAMINE-KINASE-RXN
|
|
|
|
S-adenosyl-L-methionine + 24(28)-methylene_lophenol <=> H+ + 24-ethylidenelophenol + S-adenosyl-L-homocysteine
|
2.1.1.142
cycloartenol 24-C-methyltransferase
2.1.1.143
24-methylenesterol C-methyltransferase
2.1.1.41
sterol 24-C-methyltransferase
|
–
–
–
|
|
BRENDA:
BR33800
KEGG:
R05776
MetaCyc:
2.1.1.143-RXN
SABIO-RK:
5368
|
|
|
|
8-O-methyldihydrosterigmatocystin <=> Aflatoxin_G2
|
not assigned
|
–
|
|
KEGG:
R10482
MetaCyc:
RXN-9503
|
|
|
|
24(28)-methylene_lophenol <=> 4alpha-methyl-5alpha-ergosta-8,24-dien-3beta-ol
|
5.3.3.5
cholestenol Delta-isomerase
|
–
|
|
BRENDA:
BS418315
KEGG:
R07484
MetaCyc:
RXN-4161
|
|
|
|
L-arogenate + oxaloacetate <=> prephenate + L-aspartate
|
2.6.1.1
aspartate transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.78
aspartate---prephenate aminotransferase
2.6.1.79
glutamate---prephenate aminotransferase
|
–
–
–
–
|
|
BRENDA:
BR48629
KEGG:
R01731
MetaCyc:
PREPHENATE-ASP-TRANSAMINE-RXN
SABIO-RK:
1841
|
|
|
|
geranyl_diphosphate + H2O <=> (3R)-linalool + diphosphate
|
4.2.3.25
S-linalool synthase
4.2.3.26
R-linalool synthase
|
–
–
|
|
BRENDA:
BR48698;
BS398886
KEGG:
R07632
MetaCyc:
4.2.3.26-RXN
|
|
|
|
dihydro-4-coumaroyl-CoA + NADP+ <=> 4-coumaroyl-CoA + NADPH + H+
|
1.3.1.117
hydroxycinnamoyl-CoA reductase
|
–
|
|
BRENDA:
BR52388
KEGG:
R12112
MetaCyc:
RXN-11467
|
|
|
|
ATP + (S)-beta-tyrosine + pC3'p <=> AMP + diphosphate + (S)-beta-Tyrosyl-[pcp]
|
6.2.1
|
–
|
|
KEGG:
R11367
|
|
|
|
S-adenosyl-L-methionine + 12-ethyl-8-propyl-3-vinyl-bacteriochlorophyllide_d <=> S-adenosyl-L-homocysteine + 12-ethyl-8-isobutyl-3-vinyl-bacteriochlorophyllide_d + H+
|
2.1.1.332
bacteriochlorophyllide d C-82-methyltransferase
|
–
|
|
BRENDA:
BR51852
KEGG:
R11509
MetaCyc:
RXN-17432
|
|
|
|
7-hydroxychlorophyllide_a + NADP+ <=> chlorophyllide_b + NADPH + H+
|
1.1.1.294
chlorophyll(ide) b reductase
|
–
|
|
BRENDA:
BR48851
KEGG:
R08915
|
|
|
|
cyclo-L-Trp-L-Phe + S-adenosyl-L-methionine <=> N-Methyl-cyclo(L-Trp-L-Phe) + S-adenosyl-L-homocysteine
|
2.1.1
|
–
|
|
KEGG:
R12414
|
|
|
|
1,4-dihydroxy-2-naphthoyl-CoA + H2O <=> H+ + 1,4-dihydroxy-2-naphthoate + CoA
|
3.1.2.28
1,4-dihydroxy-2-naphthoyl-CoA hydrolase
|
–
|
|
BRENDA:
BR49261
KEGG:
R07262
MetaCyc:
RXN-9311
|
|
|
|
S-adenosyl-L-methionine + 4-hydroxy-N-methyltryptamine_4-phosphate <=> S-adenosyl-L-homocysteine + psilocybin + H+
|
2.1.1.345
psilocybin synthase
|
–
|
|
BRENDA:
BR52248
KEGG:
R11936
MetaCyc:
RXN-19092
|
|
|
|
malonyl-CoA + acetyl-CoA <=> dodecanoyl-[acyl-carrier_protein]
|
not assigned
|
–
|
|
KEGG:
R11671
|
|
|
|
cannabigerolate + O2 <=> DELTA9-tetrahydrocannabinolate + H2O2
|
1.21.3.7
tetrahydrocannabinolic acid synthase
|
–
|
|
BRENDA:
BR50269
KEGG:
R12101
MetaCyc:
RXN-7854
|
|
|
|
3-dehydro-6-deoxoteasterone <=> 6-deoxotyphasterol
|
not assigned
|
–
|
|
KEGG:
R07473
|
|
|
|
sucrose_6F-phosphate + H2O <=> sucrose + phosphate
|
3.1.3.24
sucrose-phosphate phosphatase
|
–
|
|
BRENDA:
BR12744
KEGG:
R00805;
R06211
MetaCyc:
SUCROSE-PHOSPHATASE-RXN
SABIO-RK:
1150
|
|
|
|
UDP-L-rhamnose + kaempferol_3-O-glucoside <=> UDP + kaempferol_3-O-rutinoside
|
2.4.1.159
flavonol-3-O-glucoside L-rhamnosyltransferase
2.4.1.B53
|
–
–
|
|
BRENDA:
BS424290
KEGG:
R12046
|
|
|
|
(2R)-2-hydroxy-2-methylbutanenitrile <=> cyanide + 2-butanone
|
4.1.2.10
(R)-mandelonitrile lyase
4.1.2.46
aliphatic (R)-hydroxynitrile lyase
4.1.2.47
(S)-hydroxynitrile lyase
|
–
–
–
|
|
BRENDA:
BR49335;
BS1786;
BS406962
KEGG:
R09358
MetaCyc:
RXN-11733
|
|
|
|
4-dimethylallyl-L-abrine <=> chanoclavine-I
|
not assigned
|
–
|
|
KEGG:
R12104
|
|
|
|
S-adenosyl-L-methionine + daidzein <=> H+ + formononetin + S-adenosyl-L-homocysteine
|
2.1.1.212
2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase
2.1.1.231
flavonoid 4'-O-methyltransferase
2.1.1.46
isoflavone 4'-O-methyltransferase
|
–
–
–
|
|
BRENDA:
BS289634
KEGG:
R06564
MetaCyc:
RXN-3542
|
|
|
|
ATP + NAD+ <=> H+ + 3''-dehydro-ATP + NADH
|
1
|
–
|
|
KEGG:
R05668
MetaCyc:
RXN-9444
|
|
|
|
3,5,7,9,11,13,15,17,19-Nonaoxo-eicosanoyl-[acp] <=> 7,12-Decaketide_intermediate_1 + H2O
|
4.2.1
|
–
|
|
KEGG:
R09268
|
|
|
|
XMP + H2O <=> Xanthosine + phosphate
|
3.1.3.5
5'-nucleotidase
|
–
|
|
BRENDA:
BS383410
KEGG:
R02719
MetaCyc:
XMPXAN-RXN
SABIO-RK:
129
|
|
|
|
Premithramycin_A1 + dTDP-D-oliose <=> Premithramycin_A2' + dTDP + H+
|
2.4.1
|
–
|
|
KEGG:
R06717
MetaCyc:
RXN-13376
|
|
|
|
naringenin_chalcone <=> naringenin
|
5.5.1.6
chalcone isomerase
|
–
|
|
BRENDA:
BS380128
KEGG:
R02446
MetaCyc:
APIGNAR-RXN
SABIO-RK:
2380
|
|
|
|
D-fructose_1,6-bisphosphate <=> dihydroxyacetone_phosphate + D-glyceraldehyde_3-phosphate
|
4.1.2.13
fructose-bisphosphate aldolase
4.1.2.40
tagatose-bisphosphate aldolase
|
–
–
|
|
BRENDA:
BR344;
BS398846
KEGG:
R01068;
R01070
MetaCyc:
F16ALDOLASE-RXN
SABIO-RK:
1338;
3
|
|
|
|
L-tryptophan + L-proline + 2 ATP <=> brevianamide_F + 2 AMP + 2 diphosphate
|
not assigned
|
–
|
|
KEGG:
R10661
|
|
|
|
13-Desoxypaxilline + NADPH + H+ + O2 <=> Paxilline + NADP+ + H2O
|
1.14.13
|
–
|
|
KEGG:
R10359
|
|
|
|
D-fructose_1,6-bisphosphate + H2O <=> beta-D-fructose_6-phosphate + phosphate
|
3.1.3.11
fructose-bisphosphatase
3.1.3.29
N-acylneuraminate-9-phosphatase
3.1.3.37
sedoheptulose-bisphosphatase
3.1.3.7
3'(2'),5'-bisphosphate nucleotidase
|
–
–
–
–
|
|
BRENDA:
BR19198
KEGG:
R00762;
R04780
MetaCyc:
F16BDEPHOS-RXN
SABIO-RK:
10378;
1117
|
|
|
|
3-oxo-2-(cis-2''-pentenyl)-cyclopentane-1-butanoyl-CoA + acetyl-CoA <=> 3-oxo-2-(cis-2''-pentenyl)-cyclopentane-1-(3-oxohexanoyl)-CoA + CoA
|
2.3.1.16
acetyl-CoA C-acyltransferase
|
–
|
|
KEGG:
R07895
MetaCyc:
RXN-10700
|
|
|
|
UDP-glucose + an_(E)-omega-(methylthio)alkyl-thiohydroximate <=> H+ + an_aliphatic_desulfoglucosinolate + UDP
|
2.4.1.195
N-hydroxythioamide S-beta-glucosyltransferase
|
–
|
|
BRENDA:
BR52365
KEGG:
R08668;
R12045
MetaCyc:
RXN-2208
|
|
|
|
L-aspartate + ATP <=> L-4-aspartyl_phosphate + ADP
|
2.7.2.4
aspartate kinase
|
–
|
|
BRENDA:
BR47827
KEGG:
R00480
MetaCyc:
ASPARTATEKIN-RXN
SABIO-RK:
912
|
|
|
|
myo-inositol + ATP <=> H+ + D-myo-Inositol_1-phosphate + ADP
|
2.7.1.64
inositol 3-kinase
|
–
|
|
BRENDA:
BR47388
KEGG:
R07279
MetaCyc:
MYO-INOSITOL-1-KINASE-RXN
|
|
|
|
geranylgeranyl_diphosphate + isopentenyl_diphosphate <=> all-trans-hexaprenyl_diphosphate + diphosphate
|
2.5.1.82
hexaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]
2.5.1.B41
|
–
–
|
|
BRENDA:
BR49312
KEGG:
R09246
MetaCyc:
RXN-11485
|
|
|
|
(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + H2O <=> geosmin + acetone
|
4.1.99.16
geosmin synthase
|
–
|
|
BRENDA:
BR49542
KEGG:
R09487
MetaCyc:
RXN-12237
|
|
|
|
geranylgeranyl_diphosphate + H2O <=> (13E)-labda-7,13-dien-15-ol + diphosphate
|
3.1.7.10
(13E)-labda-7,13-dien-15-ol synthase
|
–
|
|
BRENDA:
BR49988
KEGG:
R09874
MetaCyc:
RXN-12892
|
|
|
|
ADP + ATP <=> ATP + ADP
|
2.4.2.12
nicotinamide phosphoribosyltransferase
2.7.1.20
adenosine kinase
2.7.4.6
nucleoside-diphosphate kinase
3.6.4.10
non-chaperonin molecular chaperone ATPase
|
–
–
–
–
|
|
BRENDA:
BS141550
KEGG:
R00124
|
|
|
|
beta-L-galactose_1-phosphate + H2O <=> L-galactopyranose + phosphate
|
3.1.3.93
L-galactose 1-phosphate phosphatase
3.1.3.B9
|
–
–
|
|
BRENDA:
BR49908;
BR50987
KEGG:
R07674
MetaCyc:
RXNQT-4142
SABIO-RK:
13655
|
|
|
|
4'',6,7-Trihydroxyisoflavone <=> glycitein
|
not assigned
|
–
|
|
KEGG:
R07717
|
|
|
|
6-hydroxyprotopine <=> Dihydrosanguinarine + H2O
|
not assigned
|
–
|
|
KEGG:
R04701
MetaCyc:
RXN-8181
|
|
|
|
feruloyl-CoA + feruloylacetyl-CoA + H2O <=> curcumin + CoA + CO2
|
2.3.1.217
curcumin synthase
|
–
|
|
BRENDA:
BR50409
KEGG:
R08810
MetaCyc:
RXN-11226
|
|
|
|
Terpendole_I + dimethylallyl_diphosphate <=> 20,21-Diprenylterpendole_I + diphosphate
|
2.5.1
|
–
|
|
KEGG:
R10369
MetaCyc:
RXN-15959
|
|
|
|
3beta-hydroxyergosta-7,24(241)-dien-4alpha-carboxylate + NAD+ <=> Episterone + NADH + CO2
|
1.1.1.418
plant 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
|
–
|
|
KEGG:
R12375
MetaCyc:
RXN-11933
|
|
|
|
gibberellin_a15 + 2-oxoglutarate + O2 <=> Gibberellin_A24 + succinate + CO2 + H2O
|
1.14.11.12
gibberellin-44 dioxygenase
1.14.20
|
–
–
|
|
KEGG:
R06323
MetaCyc:
RXN1F-163
SABIO-RK:
5905
|
|
|
|
kanamycin_C + O2 <=> 6''-Oxokanamycin_C + H2O2
|
1.1.3
|
–
|
|
KEGG:
R11268
|
|
|
|
ferruginol + 3 reduced_flavodoxin + 3 O2 <=> pisiferic_acid + 3 flavin + 4 H2O
|
1.14.14.61
carnosic acid synthase
|
–
|
|
BRENDA:
BS443561
KEGG:
R11989
|
|
|
|
L-arginine + NADPH + H+ + O2 <=> L-citrulline + NO + NADP+ + H2O
|
1.14.13.39
nitric-oxide synthase (NADPH)
1.14.14.47
nitric-oxide synthase (flavodoxin)
|
–
–
|
|
BRENDA:
BR52111;
BS394886
KEGG:
R00557
MetaCyc:
NITRIC-OXIDE-SYNTHASE-RXN
SABIO-RK:
969
|
|
|
|
N-hydroxy-L-phenylalanine + reduced_flavodoxin + O2 <=> N,N-dihydroxy-L-phenylalanine + flavin + H2O
|
1.14.14.40
phenylalanine N-monooxygenase
|
–
|
|
BRENDA:
BR49591
KEGG:
R09580
|
|
|
|
3-Hydroxy-OPC4-CoA + NAD+ <=> 3-Oxo-OPC4-CoA + NADH + H+
|
1.1.1.211
long-chain-3-hydroxyacyl-CoA dehydrogenase
1.1.1.35
3-hydroxyacyl-CoA dehydrogenase
|
–
–
|
|
KEGG:
R07898
|
|
|
|
2-Amino-4-chloro-4-pentenoic_acid <=> DL-propargylglycine + Cl- + H+
|
4.5.1
|
–
|
|
KEGG:
R12409
|
|
|
|
(-)-limonene + reduced_flavodoxin + O2 <=> (-)-trans-isopiperitenol + flavin + H2O
|
1.14.14.99
(S)-limonene 3-monooxygenase
|
–
|
|
BRENDA:
BR36763
KEGG:
R02469
|
|
|
|
gibberellin_a15 <=> gibberellin_a37
|
not assigned
|
–
|
|
KEGG:
R06334
|
|
|
|
p-coumaric_acid + CoA + ATP <=> 4-coumaroyl-CoA + AMP + diphosphate
|
6.2.1.12
4-coumarate---CoA ligase
6.2.1.2
medium-chain acyl-CoA ligase
6.2.1.30
phenylacetate---CoA ligase
|
–
–
–
|
|
BRENDA:
BR63
KEGG:
R01616
MetaCyc:
4-COUMARATE--COA-LIGASE-RXN
SABIO-RK:
1761
|
|
|
|
pseudobaptigenin + reduced_flavodoxin + O2 <=> 2'',7-Dihydroxy-4'',5''-methylenedioxyisoflavone + flavin + H2O
|
1.14.14.90
isoflavone 2'-hydroxylase
|
–
|
|
KEGG:
R07746
|
|
|
|
(1''S,5''R)-hydroxyaverantin + NAD+ <=> H+ + 5''-oxoaverantin + NADH
|
1.1.1.352
5'-hydroxyaverantin dehydrogenase
|
–
|
|
BRENDA:
BR50503
KEGG:
R10311
MetaCyc:
RXN-9484
|
|
|
|
O2 + Columbamine <=> H2O + Berberine
|
1.21.3.2
columbamine oxidase
|
–
|
|
BRENDA:
BR37078
KEGG:
R00044
MetaCyc:
COLUMBAMINE-OXIDASE-RXN
|
|
|
|
7,9,12-Decaketide_intermediate_6 <=> 12-Deoxyaklanonic_acid
|
not assigned
|
–
|
|
KEGG:
R09326
|
|
|
|
S-adenosyl-L-methionine + norbelladine <=> 4''-O-methylnorbelladine + S-adenosyl-L-homocysteine + H+
|
2.1.1.336
norbelladine O-methyltransferase
|
–
|
|
BRENDA:
BR51861
KEGG:
R08437
MetaCyc:
RXN-18122
|
|
|
|
H2O + Chlorophyll <=> chlorophyllide_a + phytol
|
3.1.1.14
chlorophyllase
|
–
|
|
BRENDA:
BR10645;
BS363953
KEGG:
R05618
MetaCyc:
CHLOROPHYLLASE-RXN;
RXN-7738
SABIO-RK:
12703;
5216
|
|
|
|
H+ + L-Dopa <=> dopamine + CO2
|
4.1.1.22
histidine decarboxylase
4.1.1.25
tyrosine decarboxylase
4.1.1.28
aromatic-L-amino-acid decarboxylase
4.1.1.53
phenylalanine decarboxylase
|
–
–
–
–
|
|
BRENDA:
BR287
KEGG:
R02080
MetaCyc:
RXN66-221
SABIO-RK:
2090
|
|
|
|
neomycin_C + 2-oxoglutarate <=> 6''''''-deamino-6''''''-oxoneomycin_C + L-glutamate
|
2.6.1.95
neomycin C transaminase
|
–
|
|
BRENDA:
BR50194
KEGG:
R08903
MetaCyc:
RXN-13175
|
|
|
|
D-glucose_6-phosphate + NAD+ <=> 3-dehydro-D-glucose_6-phosphate + NADH + H+
|
1.1.1.361
glucose-6-phosphate 3-dehydrogenase
|
–
|
|
BRENDA:
BR50739
KEGG:
R10519
MetaCyc:
RXN8J2-136
|
|
|
|
(+)-limonene + reduced_flavodoxin + O2 <=> (+)-trans-carveol + flavin + H2O
|
1.14.14.53
(R)-limonene 6-monooxygenase
|
–
|
|
BRENDA:
BR47606
KEGG:
R06119
|
|
|
|
S-adenosyl-L-methionine + uroporphyrinogen_III <=> S-adenosyl-L-homocysteine + precorrin-2 + H+
|
2.1.1.107
uroporphyrinogen-III C-methyltransferase
|
–
|
|
BRENDA:
BR51020
KEGG:
R03194
MetaCyc:
RXN-13403
|
|
|
|
5-aminoimidazole-4-carboxamide_ribonucleotide + formate + ATP <=> 5-Formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide + ADP + phosphate
|
6.3.4.23
formate---phosphoribosylaminoimidazolecarboxamide ligase
|
–
|
|
BRENDA:
BR50732
KEGG:
R06975
MetaCyc:
RXN-10066
|
|
|
|
UDP-glucose + coumaric_acid <=> H+ + 2-O-(beta-D-glucosyl)-2-hydroxycinnamate + UDP
|
2.4.1.114
2-coumarate O-beta-glucosyltransferase
2.4.1.35
phenol beta-glucosyltransferase
|
–
–
|
|
BRENDA:
BR44144;
BS321991
KEGG:
R03710
MetaCyc:
2.4.1.114-RXN
SABIO-RK:
3473
|
|
|
|
2-((1R,3S),-1,9''-dihydroxy-1''-methyl-10''-oxo-3,4,5,10''-tetrahydro-1H-benzo[g]isochromen-3''-yl)acetate <=> (S)-DNPA + H2O
|
4.2.1
|
–
|
|
KEGG:
R09308
MetaCyc:
RXN1A0-6314
|
|
|
|
dTDP-4-oxo-alpha-D-xylose <=> dTDP-3-methyl-4-oxo-alpha-D-ribopyranose
|
2.1.1
|
–
|
|
KEGG:
R11466
|
|
|
|
4-coumaroyl-CoA + feruloylacetyl-CoA + H2O <=> demethoxycurcumin + CoA + CO2
|
2.3.1.219
demethoxycurcumin synthase
|
–
|
|
BRENDA:
BR50412
KEGG:
R08809
MetaCyc:
RXN-11225
|
|
|
|
amidinoproclavaminate + H2O <=> proclavaminate + Urea
|
3.5.3.22
proclavaminate amidinohydrolase
|
–
|
|
BRENDA:
BR47584
KEGG:
R05357
MetaCyc:
3.5.3.22-RXN
|
|
|
|
3-Hydroxy-OPC6-CoA <=> trans-2-Enoyl-OPC6-CoA + H2O
|
4.2.1.17
enoyl-CoA hydratase
4.2.1.74
long-chain-enoyl-CoA hydratase
|
–
–
|
|
KEGG:
R07893
|
|
|
|
amylose <=> glycogen
|
2.4.1.18
1,4-alpha-glucan branching enzyme
2.4.1.25
4-alpha-glucanotransferase
3.2.1.1
alpha-amylase
3.2.1.116
glucan 1,4-alpha-maltotriohydrolase
3.2.1.133
glucan 1,4-alpha-maltohydrolase
3.2.1.135
neopullulanase
3.2.1.41
pullulanase
3.2.1.54
cyclomaltodextrinase
3.2.1.68
isoamylase
|
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BS322548;
BS361119;
BS371171;
BS373329;
BS380763
KEGG:
R02110;
R06186;
R06209;
R11261
MetaCyc:
GLYCOGEN-BRANCH-RXN;
RXN-4301;
RXN-7710
|
|
|
|
4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol + NAD+ <=> avenastenone + NADH + CO2
|
1.1.1.418
plant 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
|
–
|
|
KEGG:
R12376
MetaCyc:
RXN-11938
|
|
|
|
(+)-7-Isojasmonate_CoA + acetyl-CoA <=> 3-oxo-2-(cis-2''-pentenyl)-cyclopentane-1-(3-oxobutanoyl)-CoA + CoA
|
2.3.1.16
acetyl-CoA C-acyltransferase
|
–
|
|
KEGG:
R07899
MetaCyc:
RXN-10701
|
|
|
|
3-Hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA <=> 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + H2O
|
4.2.1.57
isohexenylglutaconyl-CoA hydratase
|
–
|
|
BRENDA:
BR435
KEGG:
R03493
MetaCyc:
ISOHEXENYLGLUTACONYL-COA-HYDRATASE-RXN
|
|
|
|
5,10-methylenetetrahydrofolate + 2-oxoisovalerate + H2O <=> ketopantoate + tetrahydrofolate
|
2.1.2.11
3-methyl-2-oxobutanoate hydroxymethyltransferase
|
–
|
|
BRENDA:
BR43940
KEGG:
R01226
MetaCyc:
3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN
SABIO-RK:
1455
|
|
|
|
aurachin_B + NAD+ + H2O <=> 4-hydroxy-2-methyl-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]quinolin-3(4H)-one_1-oxide + NADH + H+
|
1.1.1.394
aurachin B dehydrogenase
|
–
|
|
BRENDA:
BR51560
KEGG:
R11149
MetaCyc:
RXN-17420
|
|
|
|
phosphatidylethanolamine + H2O <=> ethanolamine + phosphatidic_acid
|
3.1.4.4
phospholipase D
|
–
|
|
BRENDA:
BS364671
KEGG:
R02051
|
|
|
|
dTDP-3-O-methyl-beta-L-rhamnose + Calicheamicin_alpha1(I) <=> dTDP + Calicheamicin_gamma(1)I
|
2.4.1
|
–
|
|
KEGG:
R11422
|
|
|
|
ent-copalyl_diphosphate <=> diphosphate + ent-kaurene
|
4.2.3.19
ent-kaurene synthase
5.5.1.13
ent-copalyl diphosphate synthase
|
–
–
|
|
BRENDA:
BR44342;
BS323512;
BS444312
KEGG:
R05092
MetaCyc:
4.2.3.19-RXN
|
|
|
|
S-adenosyl-L-methionine + 4-dimethylallyl-L-tryptophan <=> 4-dimethylallyl-L-abrine + S-adenosyl-L-homocysteine + H+
|
2.1.1.261
4-dimethylallyltryptophan N-methyltransferase
|
–
|
|
BRENDA:
BR50272
KEGG:
R10166
MetaCyc:
RXN-11386
|
|
|
|
bacteriochlorophyll_a + NADP+ <=> geranylgeranyl-bacteriochlorophyllide_a + NADPH + H+
|
1.3.1.111
geranylgeranyl-bacteriochlorophyllide a reductase
1.3.1.83
geranylgeranyl diphosphate reductase
|
–
–
|
|
BRENDA:
BR51563;
BS398896
KEGG:
R11226
MetaCyc:
RXN-17426
|
|
|
|
L-N-acetyl-2-amino-6-oxopimelate + L-glutamate <=> N-acetyl-L,L-2,6-diaminopimelate + 2-oxoglutarate
|
2.6.1
|
–
|
|
KEGG:
R04467
MetaCyc:
RXN-4822
|
|
|
|
C20818 <=> C20819
|
2.1.1
|
–
|
|
KEGG:
R10738
|
|
|
|
S-adenosyl-L-methionine + Demethylmacrocin <=> H+ + S-adenosyl-L-homocysteine + macrocin
|
2.1.1.102
demethylmacrocin O-methyltransferase
|
–
|
|
BRENDA:
BR43861
KEGG:
R02859
MetaCyc:
DEMETHYLMACROCIN-O-METHYLTRANSFERASE-RXN
|
|
|
|
p-hydroxyphenylacetaldoxime + L-cysteine + NADPH + O2 + H+ <=> S-(Hydroxyphenylacetothiohydroximoyl)-L-cysteine + NADP+ + 2 H2O
|
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
|
|
KEGG:
R10672
|
|
|
|
2-aminobenzoyl-CoA + L-Cysteinyl-protein <=> S-Anthraniloyl-L-cysteinyl-protein + CoA
|
2.3.1.262
anthraniloyl-CoA anthraniloyltransferase
|
–
|
|
KEGG:
R11586
|
|
|
|
Nonaketamide_tricyclic_intermediate <=> Pretetramid
|
not assigned
|
–
|
|
KEGG:
R09196
|
|
|
|
3,4-Dihydroxybenzaldehyde + tyramine <=> Norcraugsodine + H2O + H+
|
4.3.3
|
–
|
|
KEGG:
R08436
MetaCyc:
RXN-18120
|
|
|
|
Caffeine + NADPH + O2 + H+ <=> Theobromine + NADP+ + formaldehyde + H2O
|
1.14.13.128
7-methylxanthine demethylase
1.14.13.178
methylxanthine N1-demethylase
|
–
–
|
|
BRENDA:
BR50577
KEGG:
R07956
MetaCyc:
RXN-11513
|
|
|
|
2-Amino-5-epi-valiolone <=> 2-Aminovalienone
|
not assigned
|
–
|
|
KEGG:
R11252
|
|
|
|
geranyl_diphosphate + H2O <=> (-)-alpha-terpineol + diphosphate
|
4.2.3.108
1,8-cineole synthase
4.2.3.111
(-)-alpha-terpineol synthase
4.2.3.112
(+)-alpha-terpineol synthase
|
–
–
–
|
|
BRENDA:
BR50074;
BS444324
KEGG:
R06421
MetaCyc:
RXN-5101
|
|
|
|
heme_O <=> heme_a
|
not assigned
|
–
|
|
KEGG:
R07412
|
|
|
|
1-hydroxyneurosporene <=> all-trans-neurosporene + H2O
|
4.2.1.131
carotenoid 1,2-hydratase
|
–
|
|
BRENDA:
BS417405
KEGG:
R07532
MetaCyc:
RXN-10665
|
|
|
|
2-heptyl-4(1H)-quinolone + NADH + O2 + H+ <=> 2-heptyl-3-hydroxy-4(1H)-quinolone + NAD+ + H2O
|
1.14.13.182
2-heptyl-3-hydroxy-4(1H)-quinolone synthase
|
–
|
|
BRENDA:
BR50587
KEGG:
R10467
MetaCyc:
RXN-11849
|
|
|
|
valienol_7-phosphate <=> valienol_1-phosphate
|
not assigned
|
–
|
|
KEGG:
R11499
MetaCyc:
RXN-17383
|
|
|
|
JI-20A <=> gentamicin_C1a
|
not assigned
|
–
|
|
KEGG:
R11302
|
|
|
|
spheroidene + O2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> spheroiden-2-one + H2O + oxidized_ferredoxin
|
1.14.15.9
spheroidene monooxygenase
|
–
|
|
BRENDA:
BR49655;
BS413612
KEGG:
R07537
MetaCyc:
RXN-10670
|
|
|
|
S-adenosyl-L-methionine + Xanthosine <=> 7-methylxanthosine + S-adenosyl-L-homocysteine
|
2.1.1.158
7-methylxanthosine synthase
|
–
|
|
BRENDA:
BR48812
KEGG:
R07917
MetaCyc:
RXN-7596
SABIO-RK:
15254
|
|
|
|
S-farnesyl_protein + H2O <=> protein_C-terminal_S-farnesyl-L-cysteine + peptide
|
3.4.22
3.4.24.84
Ste24 endopeptidase
|
–
–
|
|
KEGG:
R09845
|
|
|
|
divinyl_protochlorophyllide_a + 2 H+ <=> protochlorophyllide
|
not assigned
|
–
|
|
KEGG:
R06271
|
|
|
|
OA-6129_A + 2-oxoglutarate + O2 <=> OA-6129_B2 + succinate + CO2
|
1.14.20
|
–
|
|
KEGG:
R10735
|
|
|
|
dTDP-3-dehydro-2,6-dideoxy-alpha-D-glucose <=> TDP-3-amino-2,3,6-trideoxy-alpha-D-glucose
|
not assigned
|
–
|
|
KEGG:
R08928
|
|
|
|
geraniol <=> Actinidine
|
not assigned
|
–
|
|
KEGG:
R08502
|
|
|
|
ent-7alpha-hydroxykaur-16-en-19-oate + reduced_flavodoxin + O2 <=> gibberellin_A12_aldehyde + flavin + 2 H2O
|
1.14.14.107
ent-kaurenoic acid monooxygenase
|
–
|
|
BRENDA:
BR40544
KEGG:
R06295
|
|
|
|
L-N-acetylphosphinothricin_bialophos + H2O <=> phosphinotricyl-alanyl-alanine/out + acetate
|
3.1.1
|
–
|
|
KEGG:
R08876
MetaCyc:
RXN-10840
|
|
|
|
TDP-3-amino-2,3,6-trideoxy-alpha-D-glucose <=> dTDP-D-angolosamine
|
not assigned
|
–
|
|
KEGG:
R08929
|
|
|
|
geneticin + FAD <=> 6''-Oxo-G418 + FADH2
|
not assigned
|
–
|
|
KEGG:
R11296
|
|
|
|
succinate + GTP + CoA <=> succinyl-CoA + GDP + phosphate
|
6.2.1.4
succinate---CoA ligase (GDP-forming)
|
–
|
|
BRENDA:
BR87
KEGG:
R00432
MetaCyc:
SUCCINATE--COA-LIGASE-GDP-FORMING-RXN
SABIO-RK:
259
|
|
|
|
farnesyl_phosphate + CTP <=> (2E,6E)-farnesyl_diphosphate + CDP
|
2.7.4.32
farnesyl phosphate kinase
|
–
|
|
BRENDA:
BR51977
KEGG:
R09850
MetaCyc:
RXN-11626
|
|
|
|
avenasterol + ferricytochrome_b5 + O2 + H+ <=> DELTA5,7-avenasterol + ferricytochrome_b5 + H2O
|
1.14.19.20
Delta7-sterol 5(6)-desaturase
|
–
|
|
KEGG:
R07486
MetaCyc:
RXN-4209
|
|
|
|
H+ + (2S)-2-isopropyl-3-oxosuccinate <=> 4-methyl-2-oxopentanoate + CO2
|
0.0.0.0
1.1.1.85
3-isopropylmalate dehydrogenase
|
–
–
|
|
BRENDA:
BR52894
KEGG:
R01652
MetaCyc:
RXN-7800
|
|
|
|
p-hydroxyphenylacetaldoxime + reduced_flavodoxin + O2 <=> (S)-4-hydroxymandelonitrile + flavin + 2 H2O
|
1.14.14.37
4-hydroxyphenylacetaldehyde oxime monooxygenase
|
–
|
|
BRENDA:
BR29144
KEGG:
R05728
|
|
|
|
(1R,6R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate <=> o-succinylbenzoate + H2O
|
4.2.1.113
o-succinylbenzoate synthase
|
–
|
|
BRENDA:
BR48469;
BS368326
KEGG:
R04031
MetaCyc:
O-SUCCINYLBENZOATE-COA-SYN-RXN
SABIO-RK:
3766
|
|
|
|
nocardicin_G <=> nocardicin_E
|
not assigned
|
–
|
|
KEGG:
R10903
|
|
|
|
fecosterol <=> episterol
|
not assigned
|
–
|
|
KEGG:
R07497
MetaCyc:
RXN3O-203
|
|
|
|
dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose <=> dTDP-3-dehydro-2,6-dideoxy-alpha-D-glucose
|
not assigned
|
–
|
|
KEGG:
R08927
|
|
|
|
alpha-D-mannose_1-phosphate <=> D-mannose_6-phosphate
|
5.4.2.10
phosphoglucosamine mutase
5.4.2.2
phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)
5.4.2.8
phosphomannomutase
|
–
–
–
|
|
BRENDA:
BR24;
BS1189
KEGG:
R01818
MetaCyc:
PHOSMANMUT-RXN
SABIO-RK:
69
|
|
|
|
Avermectin_B1b_aglycone + dTDP-L-oleandrose <=> Avermectin_B1b_monosaccharide + dTDP
|
2.4.1
|
–
|
|
KEGG:
R06496
|
|
|
|
demethylphylloquinone + NADPH + H+ <=> demethylphylloquinol + NADP+
|
1.6.5.12
demethylphylloquinone reductase
|
–
|
|
BRENDA:
BR51489
KEGG:
R11061
MetaCyc:
RXN-17007
|
|
|
|
(-)-limonene + reduced_flavodoxin + O2 <=> (-)-trans-carveol + flavin + H2O
|
1.14.14.51
(S)-limonene 6-monooxygenase
|
–
|
|
BRENDA:
BR36764
KEGG:
R02468
|
|
|
|
ATP + 4-methoxy-2,2''-bipyrrole-5-carbaldehyde + 2-Methyl-3-n-amyl-pyrrole <=> ADP + phosphate + prodigiosin + H+
|
6.4.1
|
–
|
|
KEGG:
R11662
MetaCyc:
RXN-15787
|
|
|
|
copalyl_diphosphate <=> stemar-13-ene + diphosphate
|
4.2.3.33
stemar-13-ene synthase
|
–
|
|
BRENDA:
BR48893
KEGG:
R09115
MetaCyc:
RXN-4882
|
|
|
|
NADP+ + CoA + (R)-mevalonate <=> H+ + NADPH + (S)-3-hydroxy-3-methylglutaryl-CoA
|
1.1.1.34
hydroxymethylglutaryl-CoA reductase (NADPH)
1.1.1.88
hydroxymethylglutaryl-CoA reductase
1.1.1.B38
|
–
–
–
|
|
BRENDA:
BR29297;
BR50597;
BS188050;
BS451044
KEGG:
R02082
MetaCyc:
1.1.1.34-RXN
SABIO-RK:
2092
|
|
|
|
(S)-2-Hydroxy-2-methyl-3-oxobutanoate <=> 3-hydroxy-3-methyl-2-oxobutanoic_acid
|
1.1.1.86
ketol-acid reductoisomerase (NADP+)
5.4.99.3
2-acetolactate mutase
|
–
–
|
|
BRENDA:
BR250
KEGG:
R03052;
R05071
MetaCyc:
2-ACETOLACTATE-MUTASE-RXN
SABIO-RK:
2898
|
|
|
|
DELTA1-piperideine + acetoacetyl-CoA + H2O <=> Pelletierine + CoA + CO2
|
not assigned
|
–
|
|
KEGG:
R05129
|
|
|
|
S-adenosyl-L-methionine + 1-hydroxyneurosporene <=> 1-methoxyneurosporene + S-adenosyl-L-homocysteine + H+
|
2.1.1
2.1.1.210
demethylspheroidene O-methyltransferase
|
–
–
|
|
KEGG:
R07533
MetaCyc:
RXN-10668
|
|
|
|
Caffeine + O2 + NADPH + H+ <=> theophylline + formaldehyde + NADP+ + H2O
|
1.13.12
1.14.13.128
7-methylxanthine demethylase
|
–
–
|
|
BRENDA:
BS417831
KEGG:
R07972
|
|
|
|
feruloyl-CoA + malonyl-CoA + hexanoyl-CoA + H2O <=> 1-Dehydro-[6]-gingerdione + 3 CoA + 2 CO2
|
not assigned
|
–
|
|
KEGG:
R08797
|
|
|
|
aggreticin + dTDP-D-boivinose <=> kerriamycin_B + dTDP
|
2.4.1
|
–
|
|
KEGG:
R06668
|
|
|
|
L-glutamyl_gamma-phosphinic_acid + acetyl-CoA <=> H+ + N-acetyldemethylphosphinothricin + CoA
|
2.3.1.183
phosphinothricin acetyltransferase
|
–
|
|
KEGG:
R08871
MetaCyc:
RXN-10837
|
|
|
|
S-adenosyl-L-methionine + 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol <=> plastoquinol + S-adenosyl-L-homocysteine + H+
|
2.1.1.295
2-methyl-6-phytyl-1,4-hydroquinone methyltransferase
|
–
|
|
BRENDA:
BR50940
KEGG:
R10709
MetaCyc:
RXN-2762
|
|
|
|
(3R,4R)-7,2''-dihydroxy-4''-methoxyisoflavanol <=> medicarpin + H2O
|
4.2.1.139
pterocarpan synthase
|
–
|
|
BRENDA:
BS422705;
BS444182
KEGG:
R07738
MetaCyc:
RXN-3602
|
|
|
|
2-(or_4-)dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + reduced_flavodoxin + O2 <=> glyceollin + flavin + 2 H2O
|
1.14.14.135
glyceollin synthase
|
–
|
|
BRENDA:
BR52439
KEGG:
R07197;
R07357
|
|
|
|
UDP-glucose + D-fructose <=> sucrose + UDP + H+
|
2.4.1.13
sucrose synthase
2.4.1.14
sucrose-phosphate synthase
|
–
–
|
|
BRENDA:
BS322050
KEGG:
R00806;
R06036
MetaCyc:
SUCROSE-SYNTHASE-RXN
SABIO-RK:
590
|
|
|
|
S-adenosyl-L-methionine + 8-demethylnovobiocic_acid <=> S-adenosyl-L-homocysteine + novobiocic_acid + H+
|
2.1.1.284
8-demethylnovobiocic acid C8-methyltransferase
|
–
|
|
BRENDA:
BR50630
KEGG:
R10454
MetaCyc:
RXN-14543
|
|
|
|
L-tyrosine + tetrahydrobiopterin + O2 <=> L-Dopa + 4a-hydroxytetrahydrobiopterin
|
1.14.16.2
tyrosine 3-monooxygenase
|
–
|
|
BRENDA:
BS377086
KEGG:
R07212
SABIO-RK:
7156
|
|
|
|
(3S)-2,3-epoxy-2,3-dihydrosqualene <=> lanosterol
|
5.4.99.17
squalene---hopene cyclase
5.4.99.7
lanosterol synthase
|
–
–
|
|
BRENDA:
BR254
KEGG:
R03199
MetaCyc:
LANOSTEROL-SYNTHASE-RXN
SABIO-RK:
3027
|
|
|
|
(13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine + reduced_flavodoxin + O2 <=> (13S,14R)-13-O-acetyl-1,8-dihydroxy-N-methylcanadine + flavin + H2O
|
1.14.14.167
(13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine 8-hydroxylase
|
–
|
|
BRENDA:
BR52562
KEGG:
R11690
|
|
|
|
D-glucose_6-phosphate <=> beta-D-fructose_6-phosphate
|
2.6.1.16
glutamine---fructose-6-phosphate transaminase (isomerizing)
5.3.1.8
mannose-6-phosphate isomerase
5.3.1.9
glucose-6-phosphate isomerase
|
–
–
–
|
|
BRENDA:
BR240
KEGG:
R00771
MetaCyc:
PGLUCISOM-RXN
SABIO-RK:
1123;
8448
|
|
|
|
fumiquinazoline_F-indoline-2,3''-diol + L-alanine + ATP <=> Fumiquinazoline_A + AMP + diphosphate + H2O + H+
|
6.3.2
|
–
|
|
KEGG:
R12419
MetaCyc:
RXN-15748
|
|
|
|
S-adenosyl-L-methionine + 3''-O-demethyl-staurosporine <=> staurosporine + S-adenosyl-L-homocysteine + H+
|
2.1.1.139
3'-demethylstaurosporine O-methyltransferase
|
–
|
|
BRENDA:
BR29466
KEGG:
R05757
MetaCyc:
2.1.1.139-RXN
|
|
|
|
Caffeine + NADH + O2 + H+ <=> paraxanthine + NAD+ + formaldehyde + H2O
|
1.14.13.128
7-methylxanthine demethylase
1.14.13.179
methylxanthine N3-demethylase
|
–
–
|
|
BRENDA:
BS411830
KEGG:
R07954
MetaCyc:
RXN-13106_WOP
|
|
|
|
S-adenosyl-L-methionine + dihydrosterigmatocystin <=> H+ + 8-O-methyldihydrosterigmatocystin + S-adenosyl-L-homocysteine
|
2.1.1.110
sterigmatocystin 8-O-methyltransferase
|
–
|
|
BRENDA:
BR50532
KEGG:
R10307
MetaCyc:
RXN-9501
|
|
|
|
UDP-glucose + scopoletin <=> H+ + scopolin + UDP
|
2.4.1.111
coniferyl-alcohol glucosyltransferase
2.4.1.126
hydroxycinnamate 4-beta-glucosyltransferase
2.4.1.128
scopoletin glucosyltransferase
2.4.1.170
isoflavone 7-O-glucosyltransferase
2.4.1.218
hydroquinone glucosyltransferase
2.4.1.237
flavonol 7-O-beta-glucosyltransferase
2.4.1.35
phenol beta-glucosyltransferase
2.4.1.358
acylphloroglucinol glucosyltransferase
|
–
–
–
–
–
–
–
–
|
|
BRENDA:
BR44152
KEGG:
R03594
MetaCyc:
SCOPOLETIN-GLUCOSYLTRANSFERASE-RXN
|
|
|
|
CoA + acetate + ATP <=> acetyl-CoA + diphosphate + AMP
|
6.2.1.1
acetate---CoA ligase
6.2.1.17
propionate---CoA ligase
6.2.1.36
3-hydroxypropionyl-CoA synthase
|
–
–
–
|
|
BRENDA:
BR60
KEGG:
R00235
MetaCyc:
ACETATE--COA-LIGASE-RXN
SABIO-RK:
179
|
|
|
|
S-adenosyl-L-methionine + (S)-norreticuline <=> S-adenosyl-L-homocysteine + (S)-reticuline
|
2.1.1.115
(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase
|
–
|
|
KEGG:
R05211
|
|
|
|
malonyl-CoA + H+ <=> 3,5-dihydroxyphenylacetyl-CoA + CoA + CO2 + H2O
|
2.3.1.246
3,5-dihydroxyphenylacetyl-CoA synthase
|
–
|
|
BRENDA:
BR51223
KEGG:
R06625
MetaCyc:
RXN-16276
|
|
|
|
S-adenosyl-L-methionine + 3-O-acetyl-4''-O-demethylpapaveroxine <=> 3-O-acetylpapaveroxine + S-adenosyl-L-homocysteine + H+
|
2.1.1.352
3-O-acetyl-4'-O-demethylpapaveroxine 4'-O-methyltransferase
|
–
|
|
BRENDA:
BR52574
KEGG:
R11692
MetaCyc:
RXN-13810
|
|
|
|
D-glucose <=> D-glucose
|
5.1.3.21
maltose epimerase
5.1.3.3
aldose 1-epimerase
|
–
–
|
|
BRENDA:
BR197
KEGG:
R01602
MetaCyc:
ALDOSE-1-EPIMERASE-RXN;
RXN-14352;
RXN0-7077;
TRANS-RXN0-574
SABIO-RK:
1750
|
|
|
|
H2O + 2-Phosphoglycolate <=> glycolate + phosphate
|
3.1.3.18
phosphoglycolate phosphatase
3.1.3.2
acid phosphatase
3.1.3.29
N-acylneuraminate-9-phosphatase
3.1.3.71
2-phosphosulfolactate phosphatase
5.4.2.4
bisphosphoglycerate mutase
|
–
–
–
–
–
|
|
BRENDA:
BR6356
KEGG:
R01334
MetaCyc:
GPH-RXN
SABIO-RK:
433
|
|
|
|
TDP-3-dimethylamino-4,6-dideoxy-alpha-D-glucopyranose + 3-alpha-mycarosylerythronolide_B <=> erythromycin_D + dTDP + H+
|
2.4.1.278
3-alpha-mycarosylerythronolide B desosaminyl transferase
|
–
|
|
BRENDA:
BR49893
KEGG:
R05531
MetaCyc:
RXN-12808
|
|
|
|
20-O-Methyl-19-chloroproansamitocin + Carbamoyl_phosphate <=> N-Demethyl-desepoxymaytansinol + phosphate
|
2.1.3
|
–
|
|
KEGG:
R09853
|
|
|
|
H+ + Phosphonopyruvate <=> phosphonoacetaldehyde + CO2
|
4.1.1.82
phosphonopyruvate decarboxylase
|
–
|
|
BRENDA:
BR48645
KEGG:
R04053
MetaCyc:
4.1.1.82-RXN
SABIO-RK:
3786
|
|
|
|
phenylacetonitrile + reduced_flavodoxin + O2 <=> (R)-mandelonitrile + flavin + H2O
|
1.14.14.44
phenylacetaldehyde oxime monooxygenase
1.14.14.77
phenylacetonitrile alpha-monooxygenase
|
–
–
|
|
BRENDA:
BR52035
KEGG:
R11733
|
|
|
|
retronecine + 2 L-isoleucine <=> senecionine
|
not assigned
|
–
|
|
KEGG:
R06726
|
|
|
|
8-Methyl-6-nonenoic_acid <=> (6E)-8-methylnon-6-enoyl-CoA
|
not assigned
|
–
|
|
KEGG:
R12628
|
|
|
|
5-[[(4,7-Dihydroxy-2-oxo-2H-1-benzopyran-3-yl)amino]carbonyl]-4-methyl-1H-pyrrole-3-carboxylate + 3-amino-4,7-dihydroxycoumarin + ATP + 2 S-adenosyl-L-methionine <=> Coumermic_acid + AMP + diphosphate + 2 S-adenosyl-L-homocysteine
|
not assigned
|
–
|
|
KEGG:
R06778
|
|
|
|
L-tyrosine + pyruvate <=> 4-hydroxyphenylpyruvate + L-alanine
|
2.6.1.12
alanine---oxo-acid transaminase
2.6.1.44
alanine---glyoxylate transaminase
2.6.1.5
tyrosine transaminase
2.6.1.51
serine---pyruvate transaminase
2.6.1.58
phenylalanine(histidine) transaminase
|
–
–
–
–
–
|
|
BRENDA:
BS353950
KEGG:
R09254
MetaCyc:
RXN3O-4157
SABIO-RK:
9834
|
|
|
|
dopamine + 4-hydroxyphenylacetaldehyde <=> H2O + (S)-norcoclaurine
|
4.2.1.78
(S)-norcoclaurine synthase
|
–
|
|
BRENDA:
BR455
KEGG:
R04305
MetaCyc:
S-NORLAUDANOSOLINE-SYNTHASE-RXN
|
|
|
|
(5aS)-5,5a-dihydrophenazine-1,6-dicarboxylate <=> 5,10-Dihydrophenazine-1,6-dicarboxylate
|
not assigned
|
–
|
|
KEGG:
R11574
MetaCyc:
RXN-12020
|
|
|
|
salutaridinol + acetyl-CoA <=> 7-O-acetylsalutaridinol + CoA
|
2.3.1.150
salutaridinol 7-O-acetyltransferase
|
–
|
|
BRENDA:
BR1626
KEGG:
R04723
MetaCyc:
2.3.1.150-RXN
|
|
|
|
all-trans-zeta-carotene + reduced_acceptor + O2 <=> all-trans-neurosporene + A + H2O
|
1.3.5.6
9,9'-dicis-zeta-carotene desaturase
1.3.99.26
all-trans-zeta-carotene desaturase
1.3.99.28
phytoene desaturase (neurosporene-forming)
1.3.99.30
phytoene desaturase (3,4-didehydrolycopene-forming)
1.3.99.31
phytoene desaturase (lycopene-forming)
|
–
–
–
–
–
|
|
BRENDA:
BS402980
KEGG:
R04798
|
|
|
|
phosphatidylcholine + H2O <=> lysophosphatidylcholine + linolenic_acid
|
3.1.1.4
phospholipase A2
|
–
|
|
KEGG:
R07859
|
|
|
|
isopenicillin_N + acyl-CoA + H2O <=> penicillin + CoA + L-2-aminoadipate
|
2.3.1.164
isopenicillin-N N-acyltransferase
|
–
|
|
KEGG:
R06361
|
|
|
|
S-(2E,6E)-farnesyl-L-cysteine + O2 + H2O <=> (2E,6E)-farnesal + L-cysteine + H2O2
|
1.8.3.5
prenylcysteine oxidase
1.8.3.6
farnesylcysteine lyase
|
–
–
|
|
BRENDA:
BR49439
KEGG:
R09562
MetaCyc:
RXN-11623
|
|
|
|
L-proline + pC3'p + ATP <=> (L-prolyl)-[peptidyl-carrier_protein] + AMP + diphosphate
|
6.2.1.53
L-proline---[L-prolyl-carrier protein] ligase
|
–
|
|
KEGG:
R06746
|
|
|
|
C20912 <=> C20913
|
not assigned
|
–
|
|
KEGG:
R10886
|
|
|
|
campesterol + O2 + reduced_acceptor <=> 6alpha-Hydroxycampestanol + H2O + acceptor
|
1.14.99
|
–
|
|
KEGG:
R07467
MetaCyc:
RXN-713
|
|
|
|
S-adenosyl-L-methionine + N-acetyl-O-demethylpuromycin <=> H+ + N-acetylpuromycin + S-adenosyl-L-homocysteine
|
2.1.1.38
O-demethylpuromycin O-methyltransferase
|
–
|
|
BRENDA:
BS319688
KEGG:
R05676
MetaCyc:
RXN-9452
|
|
|
|
neamine + S-adenosyl-L-methionine + reduced_acceptor <=> 4''-Oxonebramine + L-methionine + 5''-Deoxyadenosine + acceptor + H2O
|
not assigned
|
–
|
|
KEGG:
R11275
|
|
|
|
Aminofructose_6-phosphate + D-ribose_5-phosphate <=> Iminoerythrose_4-phosphate + sedoheptulose_7-phosphate
|
2.2.1.1
transketolase
|
–
|
|
KEGG:
R06590
|
|
|
|
ent-sandaracopimaradien-3beta-ol + reduced_flavodoxin + O2 <=> oryzalexin_D + flavin + H2O
|
1.14.14.123
oryzalexin D synthase
|
–
|
|
BRENDA:
BR51031
KEGG:
R11658
|
|
|
|
ubiquinone + D-glucose <=> ubiquinol + D-glucono-1,5-lactone
|
1.1.5.2
glucose 1-dehydrogenase (PQQ, quinone)
1.1.5.9
glucose 1-dehydrogenase (FAD, quinone)
|
–
–
|
|
BRENDA:
BR47599;
BS370875;
BS439425
KEGG:
R06620
MetaCyc:
RXN0-6373
|
|
|
|
Terpendole_E <=> Terpendole_G
|
not assigned
|
–
|
|
KEGG:
R10405
|
|
|
|
(S)-reticuline + S-adenosyl-L-methionine <=> laudanine + S-adenosyl-L-homocysteine
|
2.1.1.291
(R,S)-reticuline 7-O-methyltransferase
|
–
|
|
KEGG:
R08787;
R08788
SABIO-RK:
12709;
12710
|
|
|
|
chlorophyllide_a + O2 + NADPH + H+ <=> 7-hydroxychlorophyllide_a + H2O + NADP+
|
1.14.13.122
chlorophyllide-a oxygenase
|
–
|
|
BRENDA:
BR48662
KEGG:
R08203
MetaCyc:
RXN-7676
|
|
|
|
UDP-glucose + beta-D-gentiobiosyl_beta-D-glucosyl_crocetin <=> crocin + UDP + H+
|
2.4.1.330
beta-D-glucosyl crocetin beta-1,6-glucosyltransferase
|
–
|
|
BRENDA:
BR51085
KEGG:
R10990
MetaCyc:
RXN-8476
|
|
|
|
behenoyl-CoA + NADP+ <=> trans-docos-2-enoyl-CoA + NADPH + H+
|
1.3.1.93
very-long-chain enoyl-CoA reductase
|
–
|
|
BRENDA:
BR50149
KEGG:
R10828
MetaCyc:
RXN-13307
|
|
|
|
D-glycerate + ATP <=> H+ + 3-phospho-D-glycerate + ADP
|
2.7.1.165
glycerate 2-kinase
2.7.1.31
glycerate 3-kinase
|
–
–
|
|
BRENDA:
BR47771;
BS370516;
BS396474
KEGG:
R01514
MetaCyc:
GLY3KIN-RXN
SABIO-RK:
428
|
|
|
|
campesterol + NADPH + H+ + O2 <=> (22S)-22-hydroxycampesterol + NADP+ + H2O
|
1.14.13
1.14.99.B1
|
–
–
|
|
BRENDA:
BS396650
KEGG:
R07445
SABIO-RK:
12698
|
|
|
|
3''-Keto-3''-deoxy-ATP <=> 3''-Keto-3''-deoxy-AMP + diphosphate
|
3
|
–
|
|
KEGG:
R05669
|
|
|
|
zeaxanthin + reduced_ferredoxin_[iron-sulfur]_cluster + H+ + O2 <=> antheraxanthin + oxidized_ferredoxin + H2O
|
1.14.15.21
zeaxanthin epoxidase
|
–
|
|
BRENDA:
BR48604
KEGG:
R06946
MetaCyc:
RXN-7978
|
|
|
|
pyruvate + trans-2-octenal + H+ <=> (S)-3-acetyloctanal + CO2
|
2.2.1.12
3-acetyloctanal synthase
|
–
|
|
BRENDA:
BR51185
KEGG:
R11141
MetaCyc:
RXN-15769
|
|
|
|
L-phenylalanine <=> tropate
|
not assigned
|
–
|
|
KEGG:
R06744
|
|
|
|
loganic_acid + reduced_flavodoxin + O2 <=> secologanate + flavin + 2 H2O
|
1.14.19.62
secologanin synthase
|
–
|
|
KEGG:
R05833
|
|
|
|
(1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate + O2 + H+ <=> (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate + H2O2 + CO2
|
not assigned
|
–
|
|
KEGG:
R11570
MetaCyc:
RXN-17689
|
|
|
|
phosphatidylethanolamine + H2O <=> diacylglycerol + Phosphoethanolamine
|
3.1.4.12
sphingomyelin phosphodiesterase
3.1.4.3
phospholipase C
|
–
–
|
|
BRENDA:
BS370656
KEGG:
R02052
SABIO-RK:
2069
|
|
|
|
UDP-glucose + trans-zeatin <=> UDP + trans-zeatin_7-beta-D-glucoside
|
2.4.1
2.4.1.118
cytokinin 7-beta-glucosyltransferase
|
–
–
|
|
BRENDA:
BS356090
KEGG:
R08075
SABIO-RK:
13126
|
|
|
|
S-adenosyl-L-methionine + dTDP-4-amino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose <=> S-adenosyl-L-homocysteine + dTDP-alpha-D-forosamine + H+
|
2.1.1.324
dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose N,N-dimethyltransferase
|
–
|
|
BRENDA:
BR51593
KEGG:
R08932
MetaCyc:
RXN-17384
|
|
|
|
gibberellin_A12 <=> Gibberellin_A53
|
not assigned
|
–
|
|
KEGG:
R06329
|
|
|
|
geranyl_phosphate + H2O <=> geraniol + phosphate
|
3.1.3
3.1.3.76
lipid-phosphate phosphatase
3.1.7.1
prenyl-diphosphatase
|
–
–
–
|
|
BRENDA:
BS379794
KEGG:
R11552
MetaCyc:
RXN-17102
|
|
|
|
ent-sandaracopimaradien-3beta-ol + reduced_flavodoxin + O2 <=> oryzalexin_E + flavin + H2O
|
1.14.14.122
oryzalexin E synthase
|
–
|
|
BRENDA:
BR51030
KEGG:
R11657
|
|
|
|
S-adenosyl-L-methionine + 13-deoxycarminomycin <=> 13-deoxydaunorubicin + S-adenosyl-L-homocysteine + H+
|
2.1.1.292
carminomycin 4-O-methyltransferase
|
–
|
|
BRENDA:
BS424026
KEGG:
R06687
MetaCyc:
RXN-14826
|
|
|
|
UDP-glucose + phenylacetothiohydroximate <=> desulfoglucotropaeolin + UDP
|
2.4.1.195
N-hydroxythioamide S-beta-glucosyltransferase
|
–
|
|
BRENDA:
BR48049
KEGG:
R03213
MetaCyc:
2.4.1.195-RXN
SABIO-RK:
3040
|
|
|
|
geranyl_diphosphate + H2O <=> geraniol + diphosphate
|
3.1.7.11
geranyl diphosphate diphosphatase
3.1.7.3
monoterpenyl-diphosphatase
4.2.3.104
alpha-humulene synthase
|
–
–
–
|
|
BRENDA:
BR50059
KEGG:
R08396
MetaCyc:
RXN-17103;
RXN-8618
SABIO-RK:
12967
|
|
|
|
3-Hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA <=> 7-methyl-3-oxooct-6-enoyl-CoA + acetate
|
4.1.3.26
3-hydroxy-3-isohexenylglutaryl-CoA lyase
4.1.3.4
hydroxymethylglutaryl-CoA lyase
|
–
–
|
|
BRENDA:
BR387
KEGG:
R08090
MetaCyc:
4.1.3.26-RXN
|
|
|
|
(1E,2S)-2-methylbutanal_oxime <=> (Z)-2-methylbutanal_oxime
|
1.14.14.41
(E)-2-methylbutanal oxime monooxygenase
|
–
|
|
BRENDA:
BR51940
KEGG:
R10030
MetaCyc:
RXN-9640
|
|
|
|
L-histidine + Isovalerate <=> Dolichotheline
|
not assigned
|
–
|
|
KEGG:
R08412
|
|
|
|
9-cis-violaxanthin + O2 <=> 2-cis,4-trans-xanthoxin + (3S,5R,6S)-5,6-epoxy-3-hydroxy-5,6-dihydro-12''-apo-beta-caroten-12''-al
|
1.13.11.51
9-cis-epoxycarotenoid dioxygenase
|
–
|
|
BRENDA:
BR48573
KEGG:
R06953
MetaCyc:
RXN-7974
|
|
|
|
D-glycerate + NAD+ <=> H+ + Hydroxypyruvate + NADH
|
1.1.1.237
hydroxyphenylpyruvate reductase
1.1.1.26
glyoxylate reductase
1.1.1.27
L-lactate dehydrogenase
1.1.1.28
D-lactate dehydrogenase
1.1.1.29
glycerate dehydrogenase
1.1.1.60
2-hydroxy-3-oxopropionate reductase
1.1.1.79
glyoxylate reductase (NADP+)
1.1.1.81
hydroxypyruvate reductase
1.1.1.92
oxaloglycolate reductase (decarboxylating)
|
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BR29292;
BS188418-a
KEGG:
R01388
MetaCyc:
GLYCERATE-DEHYDROGENASE-RXN;
HYDROXYPYRUVATE-REDUCTASE-RXN_WOP
SABIO-RK:
426
|
|
|
|
S-adenosyl-L-methionine + (S)-norcoclaurine <=> H+ + S-adenosyl-L-homocysteine + (S)-Coclaurine
|
2.1.1.128
(RS)-norcoclaurine 6-O-methyltransferase
|
–
|
|
BRENDA:
BS386680
KEGG:
R05123
MetaCyc:
2.1.1.128-RXN
|
|
|
|
5-Aminopentanal <=> DELTA1-piperideine
|
not assigned
|
–
|
|
KEGG:
R06741
|
|
|
|
caffeoyl_aldehyde + NADPH <=> caffeoyl_alcohol + NADP+
|
1.1.1.195
cinnamyl-alcohol dehydrogenase
|
–
|
|
BRENDA:
BS384401
KEGG:
R06571
SABIO-RK:
6146
|
|
|
|
(1R,5aS,6R)-4a-Hydroxy-1,4,4a,5,5a,6,9,10a-octahydrophenazine-1,6-dicarboxylate <=> (1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate + H2O
|
not assigned
|
–
|
|
KEGG:
R11569
MetaCyc:
RXN-17684
|
|
|
|
(R)-mevalonate + ATP <=> (R)-3-phosphomevalonate + ADP + H+
|
2.7.1.185
mevalonate 3-kinase
|
–
|
|
BRENDA:
BR51126
KEGG:
R10779
MetaCyc:
RXN-15647
|
|
|
|
ATP + L-glutamate + [acyl-carrier_protein] <=> ADP + phosphate + gamma-L-Glutamyl-[acp]
|
6.2.1.39
[butirosin acyl-carrier protein]---L-glutamate ligase
|
–
|
|
KEGG:
R08905
|
|
|
|
Tetrangomycin <=> Tetrangulol + H2O
|
not assigned
|
–
|
|
KEGG:
R06650
|
|
|
|
(2E,6E)-farnesyl_diphosphate + protein <=> S-farnesyl_protein + diphosphate
|
2.5.1.58
protein farnesyltransferase
|
–
|
|
BRENDA:
BR47471
KEGG:
R09844
SABIO-RK:
9952
|
|
|
|
(2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + NAD+ <=> 2,3-Dihydroxybenzoate + NADH + H+
|
1.3.1.28
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
|
–
|
|
BRENDA:
BR36809
KEGG:
R01505
MetaCyc:
DHBDEHYD-RXN
|
|
|
|
UDP-glucose + kaempferol <=> kaempferol_3-O-glucoside + UDP + H+
|
2.4.1.115
anthocyanidin 3-O-glucosyltransferase
2.4.1.237
flavonol 7-O-beta-glucosyltransferase
2.4.1.357
phlorizin synthase
2.4.1.91
flavonol 3-O-glucosyltransferase
|
–
–
–
–
|
|
BRENDA:
BS323091
KEGG:
R06611
MetaCyc:
RXN1F-461
|
|
|
|
Theobromine + NADPH + O2 + H+ <=> 7-methylxanthine + NADP+ + formaldehyde + H2O
|
1.14.13.179
methylxanthine N3-demethylase
|
–
|
|
BRENDA:
BR50580
KEGG:
R07962
MetaCyc:
RXN-11516
|
|
|
|
feruloyl-CoA + (4-coumaroyl)acetyl-CoA + H2O <=> demethoxycurcumin + CoA + CO2
|
2.3.1.217
curcumin synthase
2.3.1.219
demethoxycurcumin synthase
|
–
–
|
|
BRENDA:
BS421743
KEGG:
R08808
MetaCyc:
RXN-11224
|
|
|
|
Iminoerythrose_4-phosphate + phosphoenolpyruvate + H2O <=> AminoDAHP + phosphate
|
2.5.1
|
–
|
|
KEGG:
R06591
MetaCyc:
RXN-9584
|
|
|
|
nogalaviketone + NADPH + H+ <=> Nogalavinone + NADP+
|
1.1.1
|
–
|
|
KEGG:
R09329
|
|
|
|
Paspaline + O2 + NADPH + H+ <=> Terpendole_E + NADP+ + H2O
|
1.14.13
|
–
|
|
KEGG:
R10373
|
|
|
|
N2-(2-carboxyethyl)-L-arginine + ATP <=> deoxyamidinoproclavaminate + AMP + diphosphate
|
6.3.3.4
(carboxyethyl)arginine beta-lactam-synthase
|
–
|
|
BRENDA:
BR47589
KEGG:
R05467
MetaCyc:
6.3.3.4-RXN
|
|
|
|
staurosporine_aglycone + dTDP-L-ristosamine <=> H+ + Holyrine_A + dTDP
|
2.4
2.4.1
|
–
–
|
|
KEGG:
R11122
MetaCyc:
RXN-10931
|
|
|
|
dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + NADP+ <=> dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + NADPH + H+
|
1.1.1.384
dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase
|
–
|
|
BRENDA:
BR51206
KEGG:
R05526
MetaCyc:
RXN-16262
|
|
|
|
geranyl_diphosphate + H2O <=> geranyl_phosphate + phosphate + H+
|
3.6.1.68
geranyl diphosphate phosphohydrolase
|
–
|
|
BRENDA:
BR51531
KEGG:
R11551
MetaCyc:
RXN-17104
|
|
|
|
malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ + (2S)-ethylmalonyl-CoA <=> tylactone + CoA + CO2 + H2O + NADP+
|
2.3.1
|
–
|
|
KEGG:
R06448
MetaCyc:
RXN-15064
|
|
|
|
oxaloacetate + ATP <=> CO2 + phosphoenolpyruvate + ADP
|
4.1.1.31
phosphoenolpyruvate carboxylase
4.1.1.38
phosphoenolpyruvate carboxykinase (diphosphate)
4.1.1.49
phosphoenolpyruvate carboxykinase (ATP)
|
–
–
–
|
|
BRENDA:
BR308
KEGG:
R00341
MetaCyc:
PEPCARBOXYKIN-RXN
SABIO-RK:
151
|
|
|
|
2,6,7,4''-tetrahydroxyisoflavanone <=> 6,7,4''-trihydroxyisoflavone + H2O
|
4.2.1
|
–
|
|
KEGG:
R07716
MetaCyc:
RXN-7656
|
|
|
|
2,3-Dihydrothienamycin + 2-oxoglutarate + O2 <=> Thienamycin + succinate + CO2 + H2O
|
1.14.20
|
–
|
|
KEGG:
R10740
|
|
|
|
coniferyl_alcohol <=> (-)-pinoresinol
|
not assigned
|
–
|
|
KEGG:
R12145
|
|
|
|
vindoline + Catharanthine <=> 3'',4''-Anhydrovinblastine
|
not assigned
|
–
|
|
KEGG:
R05858
|
|
|
|
paraxanthine + NADH + H+ + O2 <=> 1-Methylxanthine + NAD+ + formaldehyde + H2O
|
1.13.12
|
–
|
|
KEGG:
R07959
|
|
|
|
Dialdehyde + H+ <=> 4,21-Dehydrocorynantheine_aldehyde + H2O
|
not assigned
|
–
|
|
KEGG:
R05845
|
|
|
|
kanosamine + ATP <=> H+ + kanosamine_6-phosphate + ADP
|
2.7.1.179
kanosamine kinase
|
–
|
|
BRENDA:
BR50542
KEGG:
R06588
MetaCyc:
RXN-9581
SABIO-RK:
6163
|
|
|
|
dTDP-3-O-methyl-beta-L-rhamnose + Calicheamicin_PsAg <=> dTDP + Calicheamicin_alpha3(I)
|
2.4.1
|
–
|
|
KEGG:
R11423
|
|
|
|
sugiol + reduced_flavodoxin + O2 <=> 11-hydroxysugiol + flavin + H2O
|
1.14.14.60
ferruginol monooxygenase
|
–
|
|
BRENDA:
BS443912
KEGG:
R11988
|
|
|
|
prephenate + NAD+ <=> 4-hydroxyphenylpyruvate + CO2 + NADH
|
1.3.1.12
prephenate dehydrogenase
1.3.1.13
prephenate dehydrogenase (NADP+)
1.3.1.79
arogenate dehydrogenase [NAD(P)+]
|
–
–
–
|
|
BRENDA:
BR36797
KEGG:
R01728
MetaCyc:
PREPHENATEDEHYDROG-RXN
SABIO-RK:
1839
|
|
|
|
gamma-L-Glutamyl-L-propargylglycine + 2-oxoglutarate + O2 <=> L-gamma-Glutamyl-(3R)-L-beta-ethynylserine + succinate + CO2
|
1.14.11
|
–
|
|
KEGG:
R12411
|
|
|
|
UDP-glucose + phloretin <=> phlorizin + UDP
|
2.4.1.357
phlorizin synthase
|
–
|
|
BRENDA:
BR52415
KEGG:
R12088
MetaCyc:
RXN-11465
|
|
|
|
Tetrangomycin <=> Rabelomycin
|
not assigned
|
–
|
|
KEGG:
R06656
|
|
|
|
chorismate + NH3 <=> anthranilate + pyruvate + H2O
|
4.1.3.27
anthranilate synthase
|
–
|
|
BRENDA:
BS380574
KEGG:
R00985
SABIO-RK:
1279
|
|
|
|
3-phosphoshikimate + phosphoenolpyruvate <=> 5-enolpyruvylshikimate_3-phosphate + phosphate
|
2.5.1.19
3-phosphoshikimate 1-carboxyvinyltransferase
|
–
|
|
BRENDA:
BR47516
KEGG:
R03460
MetaCyc:
2.5.1.19-RXN
SABIO-RK:
3254
|
|
|
|
3-geranyl-4-hydroxybenzoate <=> geranylhydroquinone
|
not assigned
|
–
|
|
KEGG:
R09041
|
|
|
|
geranyl_diphosphate + 4-hydroxybenzoate <=> 3-geranyl-4-hydroxybenzoate + diphosphate
|
2.5.1.39
4-hydroxybenzoate polyprenyltransferase
2.5.1.93
4-hydroxybenzoate geranyltransferase
|
–
–
|
|
BRENDA:
BR47433
KEGG:
R05000;
R09040
MetaCyc:
RXN-8920
|
|
|
|
aclacinomycin_N + O2 <=> Aclarubicin + H2O2
|
1.1.3.45
aclacinomycin-N oxidase
|
–
|
|
BRENDA:
BR50598
KEGG:
R09334
MetaCyc:
RXN-14689
|
|
|
|
Carbamoyl_phosphate + tobramycin + ATP + H2O <=> nebramycin_5'' + AMP + diphosphate + phosphate + H+
|
6.1.2.2
nebramycin 5' synthase
|
–
|
|
BRENDA:
BR51037
KEGG:
R10767
MetaCyc:
RXN-15284
|
|
|
|
geranyl_diphosphate <=> citronellol
|
not assigned
|
–
|
|
KEGG:
R08397
|
|
|
|
S-adenosyl-L-methionine + 2-deoxy-scyllo-inosamine <=> 3-amino-2,3-dideoxy-scyllo-inosose + 5''-deoxyadenosine + L-methionine + H+
|
1.1.99.38
2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent)
|
–
|
|
BRENDA:
BR50146
KEGG:
R08893
MetaCyc:
RXN-13221
|
|
|
|
1alpha(S)-6-O-methyl-N-deacetylisoipecoside + H2O <=> 1alpha(S)-6-O-methyl-N-deacetylisoipecoside_aglycone + D-glucose
|
3.2.1
3.2.1.B16
|
–
–
|
|
BRENDA:
BS416057
KEGG:
R11682
MetaCyc:
RXN-13791
|
|
|
|
S-adenosyl-L-methionine + 16-hydroxytabersonine <=> H+ + S-adenosyl-L-homocysteine + 16-methoxytabersonine
|
2.1.1.94
tabersonine 16-O-methyltransferase
|
–
|
|
BRENDA:
BR43933
KEGG:
R05885
MetaCyc:
2.1.1.94-RXN
|
|
|
|
Avermectin_B1a_aglycone + S-adenosyl-L-methionine <=> Avermectin_A1a_aglycone + S-adenosyl-L-homocysteine
|
2.1.1
|
–
|
|
KEGG:
R06477
|
|
|
|
O-phospho-L-homoserine + H2O <=> phosphate + L-threonine
|
4.2.3.1
threonine synthase
|
–
|
|
BRENDA:
BR16083
KEGG:
R01466
MetaCyc:
THRESYN-RXN
SABIO-RK:
1642
|
|
|
|
3-devinyl-3-(1-hydroxyethyl)chlorophyllide_a <=> chlorophyllide_a + H2O
|
4.2.1.165
chlorophyllide a 31-hydratase
4.2.1.169
3-vinyl bacteriochlorophyllide d 31-hydratase
|
–
–
|
|
BRENDA:
BR51660;
BS436424
KEGG:
R09059
MetaCyc:
RXN-8785
|
|
|
|
codeine + 2-oxoglutarate + O2 <=> morphine + formaldehyde + succinate + CO2
|
1.14.11.32
codeine 3-O-demethylase
|
–
|
|
BRENDA:
BR49146
KEGG:
R09402
MetaCyc:
RXN-8152
|
|
|
|
episterol + O2 + ferricytochrome_b5 + H+ <=> 5-dehydroepisterol + H2O + ferricytochrome_b5
|
1.14.19.20
Delta7-sterol 5(6)-desaturase
|
–
|
|
BRENDA:
BS428606
KEGG:
R07491;
R07505
MetaCyc:
RXN3O-218
|
|
|
|
(13E)-8alpha-hydroxylabd-13-en-15-yl_diphosphate + H2O <=> sclareol + diphosphate
|
4.2.3.141
sclareol synthase
4.2.3.B31
|
–
–
|
|
BRENDA:
BR50478
KEGG:
R10241
MetaCyc:
RXN-9454
|
|
|
|
Cathasterone + O2 + reduced_acceptor <=> Teasterone + H2O + acceptor
|
1.14
|
–
|
|
KEGG:
R07431
|
|
|
|
CDP-diacylglycerol + H2O <=> phosphatidic_acid + CMP + H+
|
2.7.8.8
CDP-diacylglycerol---serine O-phosphatidyltransferase
3.6.1.26
CDP-diacylglycerol diphosphatase
|
–
–
|
|
BRENDA:
BR22767
KEGG:
R01797
MetaCyc:
CDPDIGLYPYPHOSPHA-RXN
|
|
|
|
1-Indolizidinone <=> Slaframine
|
not assigned
|
–
|
|
KEGG:
R08417
|
|
|
|
7,9,9''-tricis-neurosporene + a_quinone <=> 7,9,7'',9''-tetracis-lycopene + a_quinol
|
1.3.5.6
9,9'-dicis-zeta-carotene desaturase
|
–
|
|
BRENDA:
BR49639
KEGG:
R09658
|
|
|
|
(20S)-dammarenediol <=> (3S)-2,3-epoxy-2,3-dihydrosqualene + H2O
|
4.2.1.125
dammarenediol II synthase
|
–
|
|
BRENDA:
BR48943
KEGG:
R09701
MetaCyc:
RXN-8885
|
|
|
|
oxaloacetate + acetyl-CoA + phosphate + ADP <=> citrate + CoA + ATP
|
2.3.3.8
ATP citrate synthase
|
–
|
|
BRENDA:
BR44130
KEGG:
R00352
MetaCyc:
ATP-CITRATE-PRO-S--LYASE-RXN
SABIO-RK:
266
|
|
|
|
valienone_7-phosphate <=> valienol_7-phosphate
|
not assigned
|
–
|
|
KEGG:
R11498
|
|
|
|
dichlorochromopyrrolate + O2 + NADH + H+ <=> dichloroarcyriaflavin_A + CO2 + H2O + NAD+
|
1.13.12.17
dichloroarcyriaflavin A synthase
|
–
|
|
BRENDA:
BR49133
KEGG:
R09567
MetaCyc:
RXN-10845
|
|
|
|
behenoyl-CoA + malonyl-CoA <=> a_very-long-chain_3-oxoacyl-CoA + CO2 + CoA
|
2.3.1.199
very-long-chain 3-oxoacyl-CoA synthase
|
–
|
|
BRENDA:
BR50172
KEGG:
R10825
|
|
|
|
(1R)-1,4,5,10-tetrahydrophenazine-1-carboxylate + O2 + H+ <=> 5,10-Dihydrophenazine + H2O2 + CO2
|
not assigned
|
–
|
|
KEGG:
R11572
MetaCyc:
RXN-17695
|
|
|
|
dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose + 2-oxoglutarate <=> dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + L-glutamate
|
2.6.1
|
–
|
|
KEGG:
R06631
MetaCyc:
RXN-15233
|
|
|
|
OPC8-CoA + FAD <=> trans-2-Enoyl-OPC8-CoA + FADH2
|
1.3.3.6
acyl-CoA oxidase
|
–
|
|
KEGG:
R07888
|
|
|
|
neamine + 2-oxoglutarate <=> 6''-dehydroparomamine + L-glutamate
|
2.6.1.93
neamine transaminase
|
–
|
|
BRENDA:
BR50192
KEGG:
R08897
MetaCyc:
RXN-13146
|
|
|
|
6-Oxocineole + O2 + NADPH + H+ <=> 1,6,6-Trimethyl-2,7-dioxa(3,2,2)bicyclononan-3-one + H2O + NADP+
|
1.14.13.51
6-oxocineole dehydrogenase
|
–
|
|
BRENDA:
BR40414
KEGG:
R02995
MetaCyc:
6-OXOCINEOLE-DEHYDROGENASE-RXN
|
|
|
|
alpha-D-glucose_1-phosphate <=> alpha-D-glucose_6-phosphate
|
5.4.2.10
phosphoglucosamine mutase
5.4.2.2
phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)
5.4.2.3
phosphoacetylglucosamine mutase
5.4.2.5
phosphoglucomutase (glucose-cofactor)
5.4.2.6
beta-phosphoglucomutase
5.4.2.8
phosphomannomutase
|
–
–
–
–
–
–
|
|
BRENDA:
BS1161
KEGG:
R00959
SABIO-RK:
11;
9261
|
|
|
|
S-adenosyl-L-methionine + nocardicin_G <=> isonocardicin_C + S-methyl-5''-thioadenosine + H+
|
2.5.1.38
isonocardicin synthase
|
–
|
|
BRENDA:
BR44284
KEGG:
R10881
MetaCyc:
RXN-17837
|
|
|
|
cis-trans-nepetalactol + reduced_flavodoxin + O2 <=> 7-deoxyloganetic_alcohol + flavin + H2O
|
1.14.14.161
nepetalactol monooxygenase
|
–
|
|
BRENDA:
BR52520
KEGG:
R12231
|
|
|
|
deacetoxyvindoline + 2-oxoglutarate + O2 <=> deacetylvindoline + succinate + CO2
|
1.14.11.20
deacetoxyvindoline 4-hydroxylase
|
–
|
|
BRENDA:
BR40516
KEGG:
R05857
MetaCyc:
1.14.11.20-RXN
|
|
|
|
(R)-2,3-dihydroxy-3-methylbutanoate + NADP+ <=> 3-hydroxy-3-methyl-2-oxobutanoic_acid + NADPH + H+
|
1.1.1.86
ketol-acid reductoisomerase (NADP+)
|
–
|
|
KEGG:
R04440
SABIO-RK:
8850
|
|
|
|
3-Methylxanthine + NADH + O2 + H+ <=> xanthine + NAD+ + formaldehyde + H2O
|
1.14.13.128
7-methylxanthine demethylase
1.14.13.179
methylxanthine N3-demethylase
|
–
–
|
|
BRENDA:
BR50581-a
KEGG:
R07967
MetaCyc:
RXN-13109_WOP
|
|
|
|
loganic_acid <=> 10-Deoxygeniposidic_acid
|
not assigned
|
–
|
|
KEGG:
R05898
|
|
|
|
L-tyrosine + O2 <=> L-Dopa
|
1.10.3.1
catechol oxidase
1.14.18.1
tyrosinase
|
–
–
|
|
BRENDA:
BR50166
KEGG:
R00031;
R00731
MetaCyc:
RXN-5861
SABIO-RK:
1094;
622
|
|
|
|
(22S,24R)-22-hydroxy-5alpha-ergostan-3-one + NADP+ <=> H+ + (22S)-22-hydroxycampest-4-en-3-one + NADPH
|
1.3.1
1.3.1.22
3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
|
–
–
|
|
KEGG:
R07447
MetaCyc:
RXN-4229
|
|
|
|
heme + reduced_acceptor + O2 + H+ <=> 5-oxo-delta-bilirubin + Fe2+ + formaldehyde + acceptor + H2O
|
1.14.99.48
heme oxygenase (staphylobilin-producing)
|
–
|
|
BRENDA:
BR50750
KEGG:
R10468
MetaCyc:
RXN-14696
|
|
|
|
L-Histidinol_phosphate + 2-oxoglutarate <=> 3-(Imidazol-4-yl)-2-oxopropyl_phosphate + L-glutamate
|
2.6.1.9
histidinol-phosphate transaminase
|
–
|
|
BRENDA:
BR47443
KEGG:
R03243
MetaCyc:
HISTAMINOTRANS-RXN
SABIO-RK:
3064
|
|
|
|
p-coumaric_acid <=> caffeic_acid
|
1.14.13
|
–
|
|
KEGG:
R07826
|
|
|
|
trans-5-O-caffeoylshikimate + CoA <=> caffeoyl-CoA + shikimate
|
2.3.1
2.3.1.133
shikimate O-hydroxycinnamoyltransferase
2.3.1.99
quinate O-hydroxycinnamoyltransferase
|
–
–
–
|
|
BRENDA:
BS320440
KEGG:
R07433
MetaCyc:
RXN-2621
|
|
|
|
UDP-glucose + H2O <=> UMP + alpha-D-aldose_1-phosphate + H+
|
3.1.4.1
phosphodiesterase I
3.6.1.45
UDP-sugar diphosphatase
3.6.1.8
ATP diphosphatase
3.6.1.9
nucleotide diphosphatase
|
–
–
–
–
|
|
BRENDA:
BR3333;
BS139792;
BS402967
KEGG:
R00287;
R03986
MetaCyc:
UDPSUGARHYDRO-RXN
SABIO-RK:
446
|
|
|
|
Coumermic_acid + 2 dTDP-beta-L-noviose + 2 S-adenosyl-L-methionine <=> N,N'-bis(7-[[(2R,3R,4S,5R)-3,4-dihydroxy-5-methoxy-6,6-dimethyltetrahydro-2H-pyran-2-yl]oxy]-4-hydroxy-8-methyl-2-oxo-2H-chromen-3-yl)-3-methyl-1H-pyrrole-2,4-dicarboxamide + 2 dTDP + 2 S-adenosyl-L-homocysteine
|
not assigned
|
–
|
|
KEGG:
R06767
|
|
|
|
9-cis-beta-carotene + O2 <=> 9-cis-10''-apo-beta-carotenal + beta-ionone
|
1.13.11.68
9-cis-beta-carotene 9',10'-cleaving dioxygenase
1.13.11.71
carotenoid-9',10'-cleaving dioxygenase
|
–
–
|
|
BRENDA:
BR50251
KEGG:
R10557
MetaCyc:
RXN-13642
|
|
|
|
L-dihydroanticapsin + NAD+ <=> anticapsin + NADH + H+
|
1.1.1.385
dihydroanticapsin dehydrogenase
|
–
|
|
BRENDA:
BR51207
KEGG:
R10917
MetaCyc:
RXN-16285
|
|
|
|
(2Z,6E)-farnesyl_diphosphate + n isopentenyl_diphosphate <=> n diphosphate + trans,poly-cis-polyprenyl_diphosphate
|
2.5.1.88
trans,polycis-polyprenyl diphosphate synthase [(2Z,6E)-farnesyl diphosphate specific]
|
–
|
|
BRENDA:
BS407586
KEGG:
R09731
|
|
|
|
ethanol + 2 ferricytochrome_c <=> acetaldehyde + 2 ferricytochrome_c
|
1.1.2.8
alcohol dehydrogenase (cytochrome c)
1.1.2.9
1-butanol dehydrogenase (cytochrome c)
|
–
–
|
|
BRENDA:
BS424803
KEGG:
R05198
|
|
|
|
(2E,6E)-farnesyl_diphosphate + isopentenyl_diphosphate <=> octaprenyl_diphosphate + diphosphate
|
2.5.1.90
all-trans-octaprenyl-diphosphate synthase
2.5.1.91
all-trans-decaprenyl-diphosphate synthase
|
–
–
|
|
BRENDA:
BR49324
KEGG:
R09248
MetaCyc:
RXN-8992
|
|
|
|
aklavinone + dTDP-beta-L-rhodosamine <=> aclacinomycin_T + dTDP + H+
|
2.4.1.326
aklavinone 7-L-rhodosaminyltransferase
|
–
|
|
BRENDA:
BR51043
KEGG:
R09331
MetaCyc:
RXN-14853
|
|
|
|
7-hydroxymethylchlorophyll_a + NAD+ <=> chlorophyll_b + NADH
|
1.1.1.294
chlorophyll(ide) b reductase
|
–
|
|
KEGG:
R09069
MetaCyc:
RXN-7678_WOP
|
|
|
|
acetaldehyde + NADP+ + H2O <=> acetate + NADPH + H+
|
1.2.1
1.2.1.19
aminobutyraldehyde dehydrogenase
1.2.1.24
succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.26
2,5-dioxovalerate dehydrogenase
1.2.1.3
aldehyde dehydrogenase (NAD+)
1.2.1.4
aldehyde dehydrogenase (NADP+)
1.2.1.5
aldehyde dehydrogenase [NAD(P)+]
1.2.1.8
betaine-aldehyde dehydrogenase
1.2.1.88
L-glutamate gamma-semialdehyde dehydrogenase
|
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BS231682
KEGG:
R00711
MetaCyc:
RXN0-3962
SABIO-RK:
541
|
|
|
|
squalene + reduced_flavodoxin + O2 <=> (3S)-2,3-epoxy-2,3-dihydrosqualene + flavin + H2O
|
1.14.14.17
squalene monooxygenase
|
–
|
|
BRENDA:
BR40381
KEGG:
R02874
|
|
|
|
C20817 <=> C20818
|
2.1.1
|
–
|
|
KEGG:
R10737
|
|
|
|
neoxanthin <=> 9''-cis-neoxanthin
|
5.2.1
|
–
|
|
KEGG:
R06949
MetaCyc:
RXN-8074
|
|
|
|
6-deoxocathasterone + O2 <=> 6-deoxoteasterone + H2O
|
1.14
|
–
|
|
KEGG:
R07448
|
|
|
|
S-adenosyl-L-methionine + putrescine <=> H+ + S-adenosyl-L-homocysteine + N-methylputrescine
|
2.1.1.53
putrescine N-methyltransferase
|
–
|
|
BRENDA:
BR43902
KEGG:
R01153
MetaCyc:
PUTRESCINE-N-METHYLTRANSFERASE-RXN
SABIO-RK:
1394
|
|
|
|
L-threonine <=> glycine + acetaldehyde
|
4.1.2.26
phenylserine aldolase
4.1.2.42
D-threonine aldolase
4.1.2.48
low-specificity L-threonine aldolase
4.1.2.5
L-threonine aldolase
|
–
–
–
–
|
|
BRENDA:
BR373;
BR48467
KEGG:
R00751;
R08195;
R08196
MetaCyc:
4.1.2.42-RXN;
RXN-9702;
THREONINE-ALDOLASE-RXN
SABIO-RK:
1110
|
|
|
|
geranylgeranyl_diphosphate <=> diphosphate + taxa-4,11-diene
|
4.2.3.17
taxadiene synthase
|
–
|
|
BRENDA:
BR44341
KEGG:
R06305
MetaCyc:
4.2.3.17-RXN
|
|
|
|
adonirubin + reduced_ferredoxin_[iron-sulfur]_cluster + H+ + O2 <=> (3S,3''S)-astaxanthin + oxidized_ferredoxin + H2O
|
1.14.15.24
beta-carotene 3-hydroxylase
|
–
|
|
BRENDA:
BS417476
KEGG:
R07572
MetaCyc:
RXN-8187
|
|
|
|
5-epi-valiolone <=> 2-Keto-5-epi-valiolone
|
not assigned
|
–
|
|
KEGG:
R11253
|
|
|
|
tryptamine + secologanin <=> strictosidine + H2O
|
4.3.3.2
strictosidine synthase
|
–
|
|
BRENDA:
BR48360
KEGG:
R03738
MetaCyc:
STRICTOSIDINE-SYNTHASE-RXN
|
|
|
|
OA-6129_B2 <=> OA-6129_B1
|
not assigned
|
–
|
|
KEGG:
R10750
|
|
|
|
XMP + diphosphate <=> xanthine + 5-phospho-alpha-D-ribose_1-diphosphate
|
2.4.2.22
xanthine phosphoribosyltransferase
2.4.2.7
adenine phosphoribosyltransferase
2.4.2.8
hypoxanthine phosphoribosyltransferase
|
–
–
–
|
|
BRENDA:
BR47505
KEGG:
R02142
MetaCyc:
XANPRIBOSYLTRAN-RXN
SABIO-RK:
194
|
|
|
|
3-devinyl-3-(1-hydroxyethyl)chlorophyllide_a <=> 3-deacetyl-3-vinylbacteriochlorophyllide_a + H2O
|
4.2.1.165
chlorophyllide a 31-hydratase
4.2.1.169
3-vinyl bacteriochlorophyllide d 31-hydratase
|
–
–
|
|
BRENDA:
BR51661
KEGG:
R09054
MetaCyc:
RXN-8793
|
|
|
|
4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD+ <=> cycloeucalenone + NADH + CO2
|
1.1.1.418
plant 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
|
–
|
|
BRENDA:
BS446830
KEGG:
R12371
MetaCyc:
RXN-11928
|
|
|
|
alpha-Aminoadipoyl-S-acyl_enzyme + NADPH + H+ <=> (S)-2-amino-6-oxohexanoate + Holo-Lys2 + NADP+
|
1.2.1.95
L-2-aminoadipate reductase
|
–
|
|
KEGG:
R04390
|
|
|
|
phenazine-1-carboxylic_acid + NADH + O2 + H+ <=> 1-hydroxyphenazine + NAD+ + CO2 + H2O
|
1.14.13.218
5-methylphenazine-1-carboxylate 1-monooxygenase
|
–
|
|
KEGG:
R11578
MetaCyc:
RXN-17175
|
|
|
|
4-hydroxybenzoyl-CoA + H2O <=> H+ + 4-hydroxybenzoate + CoA
|
3.1.2.2
palmitoyl-CoA hydrolase
3.1.2.20
acyl-CoA hydrolase
3.1.2.23
4-hydroxybenzoyl-CoA thioesterase
|
–
–
–
|
|
BRENDA:
BR2508
KEGG:
R01301
MetaCyc:
3.1.2.23-RXN
SABIO-RK:
1516
|
|
|
|
dTDP-beta-L-mycarose + NADP+ <=> dTDP-3-methyl-4-oxo-2,6-dideoxy-L-allose + NADPH + H+
|
1.1.1
|
–
|
|
KEGG:
R06436
MetaCyc:
RXN-12935
|
|
|
|
6-Deoxocastasterone + O2 + reduced_flavodoxin <=> 6alpha-Hydroxy-castasterone + H2O + flavin
|
1.14
|
–
|
|
KEGG:
R07450
|
|
|
|
isonocardicin_A <=> nocardicin_A
|
5.1.1.14
nocardicin A epimerase
|
–
|
|
BRENDA:
BR167
KEGG:
R03073
MetaCyc:
NOCARDICIN-A-EPIMERASE-RXN
|
|
|
|
malonyl-CoA + 6 methylmalonyl-CoA + 6 NADPH + 6 H+ <=> 8,8a-deoxyoleandolide + 7 CoA + 7 CO2 + H2O + 6 NADP+
|
not assigned
|
–
|
|
KEGG:
R06453
|
|
|
|
5-O-p-coumaroylquinic_acid + reduced_flavodoxin + O2 <=> chlorogenic_acid + flavin + H2O
|
1.14.14.96
5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase
|
–
|
|
BRENDA:
BR37109
KEGG:
R04342
|
|
|
|
geraniol <=> beta-Skytanthine
|
not assigned
|
–
|
|
KEGG:
R08501
|
|
|
|
tryprostatin_B + reduced_flavodoxin + O2 <=> 6-hydroxytryprostatin_B + flavin + H2O
|
1.14.14.118
tryprostatin B 6-hydroxylase
|
–
|
|
BRENDA:
BR50525
KEGG:
R10321
|
|
|
|
dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose <=> dTDP-4-oxo-2,6-dideoxy-L-mannose
|
5.1.3
|
–
|
|
KEGG:
R08597
MetaCyc:
RXN-12928
|
|
|
|
ATP + L-2,3-diaminopropionic_acid + citrate <=> AMP + diphosphate + 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate + H+
|
6.3.2.54
L-2,3-diaminopropanoate---citrate ligase
|
–
|
|
BRENDA:
BR52706
KEGG:
R12308
MetaCyc:
RXN-19820
|
|
|
|
CMP-5'-phosphonoformate + 3-phospho-D-glycerate <=> 1-carboxyvinyl_carboxyphosphonate + CMP + phosphate
|
not assigned
|
–
|
|
KEGG:
R08887
|
|
|
|
alpha-D-glucose_1-phosphate <=> D-glucose_6-phosphate
|
5.4.2.10
phosphoglucosamine mutase
5.4.2.2
phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)
5.4.2.3
phosphoacetylglucosamine mutase
5.4.2.5
phosphoglucomutase (glucose-cofactor)
5.4.2.8
phosphomannomutase
|
–
–
–
–
–
|
|
BRENDA:
BR18;
BS1162
KEGG:
R08639
MetaCyc:
PHOSPHOGLUCMUT-RXN;
RXN-16999
SABIO-RK:
12817;
7674
|
|
|
|
20,21-Diprenylterpendole_J + 3 O2 + 3 NADPH + 3 H+ <=> Lolitrem_E + 3 NADP+ + 4 H2O
|
1.14.13
|
–
|
|
KEGG:
R10692
|
|
|
|
Papaveroxine <=> narcotine_hemiacetal
|
not assigned
|
–
|
|
KEGG:
R10018
|
|
|
|
S-adenosyl-L-methionine + genistein <=> H+ + Biochanin_A + S-adenosyl-L-homocysteine
|
2.1.1.155
kaempferol 4'-O-methyltransferase
2.1.1.212
2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase
2.1.1.231
flavonoid 4'-O-methyltransferase
2.1.1.46
isoflavone 4'-O-methyltransferase
|
–
–
–
–
|
|
BRENDA:
BS289635
KEGG:
R02931
MetaCyc:
RXN-3645
|
|
|
|
naringenin + O2 + reduced_flavodoxin <=> 2,4'',5,7-tetrahydroxyisoflavanone + H2O + flavin
|
1.14.14.87
2-hydroxyisoflavanone synthase
|
–
|
|
BRENDA:
BR50515
KEGG:
R07778
|
|
|
|
acetoacetyl-CoA + H2O + acetyl-CoA <=> H+ + CoA + (S)-3-hydroxy-3-methylglutaryl-CoA
|
2.3.3.10
hydroxymethylglutaryl-CoA synthase
|
–
|
|
BRENDA:
BR44119
KEGG:
R01978
MetaCyc:
HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN
SABIO-RK:
2021
|
|
|
|
CTP + diacylglycerol <=> CDP + phosphatidic_acid + H+
|
2.7.1.174
diacylglycerol kinase (CTP)
|
–
|
|
BRENDA:
BR49008
KEGG:
R09944
MetaCyc:
RXN-12959
|
|
|
|
rhodomycin_D + H2O <=> 10-carboxy-13-deoxycarminomycin + methanol + H+
|
3.1.1
|
–
|
|
KEGG:
R06685
MetaCyc:
RXN-14856
|
|
|
|
S-adenosyl-L-methionine <=> H+ + S-methyl-5''-thioadenosine + 1-aminocyclopropane-1-carboxylate
|
4.4.1.14
1-aminocyclopropane-1-carboxylate synthase
|
–
|
|
BRENDA:
BR3440;
BS368525
KEGG:
R00179
MetaCyc:
4.4.1.14-RXN
SABIO-RK:
732
|
|
|
|
shikimate + ATP <=> H+ + 3-phosphoshikimate + ADP
|
2.7.1.71
shikimate kinase
|
–
|
|
BRENDA:
BR47798
KEGG:
R02412
MetaCyc:
SHIKIMATE-KINASE-RXN
SABIO-RK:
2350
|
|
|
|
5-COOH-porphyrinogen_I + acceptor <=> Coproporphyrin_I + reduced_acceptor + 6 H+
|
not assigned
|
–
|
|
KEGG:
R04973
|
|
|
|
butyryl-CoA + FAD <=> crotonyl-CoA + FADH2
|
1.3.3.6
acyl-CoA oxidase
1.3.8.1
short-chain acyl-CoA dehydrogenase
1.3.8.4
isovaleryl-CoA dehydrogenase
1.3.8.7
medium-chain acyl-CoA dehydrogenase
1.3.99
|
–
–
–
–
–
|
|
BRENDA:
BS414397
KEGG:
R01175
SABIO-RK:
1412
|
|
|
|
gentamicin_A2 + NAD+ <=> 3''''-Oxogentamicin_A2 + NADH + H+
|
1.1.1
|
–
|
|
KEGG:
R11290
|
|
|
|
Phosphonoformate + CTP <=> CMP-5''-phosphonoformate + diphosphate
|
2.7.7.93
phosphonoformate cytidylyltransferase
|
–
|
|
BRENDA:
BR51763
KEGG:
R08867
MetaCyc:
RXN-10834
|
|
|
|
an_alcohol + NADP+ <=> an_aldehyde + NADPH + H+
|
1.1.1.1
alcohol dehydrogenase
1.1.1.184
carbonyl reductase (NADPH)
1.1.1.191
indole-3-acetaldehyde reductase (NADPH)
1.1.1.195
cinnamyl-alcohol dehydrogenase
1.1.1.2
alcohol dehydrogenase (NADP+)
1.1.1.21
aldose reductase
1.1.1.215
gluconate 2-dehydrogenase
1.1.1.263
1,5-anhydro-D-fructose reductase
1.1.1.265
3-methylbutanal reductase
1.1.1.283
methylglyoxal reductase (NADPH)
1.1.1.4
(R,R)-butanediol dehydrogenase
1.1.1.61
4-hydroxybutyrate dehydrogenase
1.1.1.71
alcohol dehydrogenase [NAD(P)+]
1.1.1.72
glycerol dehydrogenase (NADP+)
1.1.1.79
glyoxylate reductase (NADP+)
1.1.1.80
isopropanol dehydrogenase (NADP+)
1.1.1.91
aryl-alcohol dehydrogenase (NADP+)
1.1.1.97
3-hydroxybenzyl-alcohol dehydrogenase
|
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BR29248;
BS139551
KEGG:
R00625;
R00746;
R07328
MetaCyc:
ALCOHOL-DEHYDROGENASE-NADP+-RXN;
ALCOHOL-DEHYDROGENASE-NADPORNOP+-RXN;
RXN-12484
SABIO-RK:
49
|
|
|
|
H2O + GTP <=> H+ + diphosphate + 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone_5'-phosphate + formate
|
3.5.4.25
GTP cyclohydrolase II
|
–
|
|
BRENDA:
BR26117
KEGG:
R00425
MetaCyc:
GTP-CYCLOHYDRO-II-RXN
SABIO-RK:
880
|
|
|
|
cis-3,4-leucopelargonidin + NADP+ <=> (+)-dihydrokaempferol + NADPH + H+
|
1.1.1.219
dihydroflavonol 4-reductase
|
–
|
|
BRENDA:
BS230655;
BS394832
KEGG:
R03123
MetaCyc:
DIHYDROKAEMPFEROL-4-REDUCTASE-RXN
|
|
|
|
geranyl_diphosphate <=> (+)-camphene + diphosphate
|
4.2.3.116
(+)-camphene synthase
4.2.3.20
(R)-limonene synthase
|
–
–
|
|
BRENDA:
BR50079
KEGG:
R09971
MetaCyc:
RXN-8576
|
|
|
|
N-acetyldemethyl_phosphinothricin_tripeptide + methylcobalamin + S-adenosyl-L-methionine + H+ + e- <=> L-N-acetylphosphinothricin_bialophos + Cobalamin + 5''-Deoxyadenosine + L-methionine
|
2.1.1.326
N-acetyldemethylphosphinothricin P-methyltransferase
|
–
|
|
KEGG:
R08875
|
|
|
|
cathenamine <=> 4,21-Dehydrogeissoschizine
|
not assigned
|
–
|
|
KEGG:
R05846
MetaCyc:
RXN-19979
|
|
|
|
dTDP-4-ethylamino-3-O-methyl-2,4-dideoxy-L-threo-pentopyranose + Calicheamicin_alpha3(I) <=> dTDP + Calicheamicin_gamma(1)I
|
2.4.2
|
–
|
|
KEGG:
R11421
|
|
|
|
4-coumaroyl-CoA + shikimate <=> 4-coumaroylshikimate + CoA
|
2.3.1.133
shikimate O-hydroxycinnamoyltransferase
2.3.1.140
rosmarinate synthase
2.3.1.99
quinate O-hydroxycinnamoyltransferase
|
–
–
–
|
|
BRENDA:
BR43994
KEGG:
R02416
MetaCyc:
2.3.1.133-RXN
|
|
|
|
D-ribulose_5-phosphate <=> H+ + formate + L-3,4-dihydroxybutan-2-one_4-phosphate
|
4.1.99.12
3,4-dihydroxy-2-butanone-4-phosphate synthase
|
–
|
|
BRENDA:
BR48836
KEGG:
R07281
MetaCyc:
DIOHBUTANONEPSYN-RXN
SABIO-RK:
9052
|
|
|
|
paraxanthine + NADPH + O2 + H+ <=> 7-methylxanthine + NADP+ + formaldehyde + H2O
|
1.14.13.128
7-methylxanthine demethylase
1.14.13.178
methylxanthine N1-demethylase
|
–
–
|
|
BRENDA:
BR50579
KEGG:
R07958
MetaCyc:
RXN-11517
|
|
|
|
S-adenosyl-L-methionine + 8,12-diethyl-3-vinyl-bacteriochlorophyllide_d <=> S-adenosyl-L-homocysteine + 12-ethyl-8-propyl-3-vinyl-bacteriochlorophyllide_d + H+
|
2.1.1.332
bacteriochlorophyllide d C-82-methyltransferase
|
–
|
|
BRENDA:
BR51851
KEGG:
R11508
MetaCyc:
RXN-17431
|
|
|
|
(+)-epi-isozizaene + O2 + NADPH + H+ <=> (5R)-albaflavenol + H2O + NADP+
|
1.14.13.106
epi-isozizaene 5-monooxygenase
|
–
|
|
BRENDA:
BR48979
KEGG:
R08853
MetaCyc:
RXN-9351
|
|
|
|
dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose <=> dTDP-3-amino-4-oxo-2,3,6-trideoxy-L-allose
|
not assigned
|
–
|
|
KEGG:
R11138
|
|
|
|
ATP + alpha-D-glucose <=> ADP + alpha-D-glucose_6-phosphate
|
2.7.1.1
hexokinase
2.7.1.2
glucokinase
|
–
–
|
|
KEGG:
R01786
SABIO-RK:
10
|
|
|
|
CoA + H2O <=> adenosine_3,5''-bisphosphate + 4''-phosphopantetheine + H+
|
3.6.1
3.6.1.22
NAD+ diphosphatase
3.6.1.55
8-oxo-dGTP diphosphatase
3.6.1.M6
|
–
–
–
–
|
|
KEGG:
R10747
MetaCyc:
RXN-10811
SABIO-RK:
14538
|
|
|
|
acetyl-CoA + Thienamycin <=> CoA + N-Acetylthienamycin
|
2.3.1
|
–
|
|
KEGG:
R10745
|
|
|
|
Fe-coproporphyrin_III + H+ <=> coproporphyrin_III + Fe2+
|
4.99.1.9
coproporphyrin ferrochelatase
|
–
|
|
BRENDA:
BR51722
KEGG:
R11329
MetaCyc:
RXN-17518
|
|
|
|
naringenin + 2-oxoglutarate + O2 <=> (+)-dihydrokaempferol + succinate + CO2
|
1.14.11.9
flavanone 3-dioxygenase
|
–
|
|
BRENDA:
BS288657;
BS402787
KEGG:
R02444
MetaCyc:
NARINGENIN-3-DIOXYGENASE-RXN
|
|
|
|
Mithramycin_DK <=> mithramycin
|
not assigned
|
–
|
|
KEGG:
R09354
|
|
|
|
2,4-dihydroxycinnamoyl-CoA <=> umbelliferone + CoA
|
not assigned
|
–
|
|
KEGG:
R12310
MetaCyc:
RXN-12965
|
|
|
|
D-ribulose_1,5-bisphosphate + O2 <=> 2-Phosphoglycolate + 3-phospho-D-glycerate + H+
|
1.13.11
4.1.1.39
ribulose-bisphosphate carboxylase
|
–
–
|
|
BRENDA:
BS1442
KEGG:
R03140
MetaCyc:
RXN-961
SABIO-RK:
8708
|
|
|
|
loganin + reduced_flavodoxin + O2 <=> secologanin + flavin + 2 H2O
|
1.14.19.62
secologanin synthase
|
–
|
|
BRENDA:
BR40360
KEGG:
R03555
|
|
|
|
S-adenosyl-L-methionine + Tetracenomycin_E <=> tetracenomycin_A2 + S-adenosyl-L-homocysteine
|
2.1.1
|
–
|
|
KEGG:
R06703
MetaCyc:
RXN-15436
|
|
|
|
geranyl_diphosphate + H2O <=> Sabinene_hydrate + diphosphate
|
4.2.3.11
sabinene-hydrate synthase
|
–
|
|
BRENDA:
BR48349
KEGG:
R02006
MetaCyc:
4.2.3.11-RXN
|
|
|
|
H+ + alpha-D-mannose_1-phosphate + GTP <=> GDP-mannose + diphosphate
|
2.7.7.13
mannose-1-phosphate guanylyltransferase
2.7.7.28
nucleoside-triphosphate-aldose-1-phosphate nucleotidyltransferase
2.7.7.30
fucose-1-phosphate guanylyltransferase
2.7.7.34
glucose-1-phosphate guanylyltransferase
|
–
–
–
–
|
|
BRENDA:
BR47862;
BS358533
KEGG:
R00885
MetaCyc:
2.7.7.13-RXN
SABIO-RK:
15252;
587;
8539
|
|
|
|
S-adenosyl-L-methionine + N-acetylserotonin <=> H+ + S-adenosyl-L-homocysteine + Melatonin
|
2.1.1.4
acetylserotonin O-methyltransferase
|
–
|
|
BRENDA:
BR40580
KEGG:
R03130
MetaCyc:
ACETYLSEROTONIN-O-METHYLTRANSFERASE-RXN
SABIO-RK:
2965
|
|
|
|
H+ + phosphoenolpyruvate <=> Phosphonopyruvate
|
5.4.2.9
phosphoenolpyruvate mutase
|
–
|
|
BRENDA:
BR48374
KEGG:
R00661
MetaCyc:
PHOSPHOENOLPYRUVATE-MUTASE-RXN
|
|
|
|
L-Histidinol + NAD+ <=> H+ + L-histidinal + NADH
|
1.1.1.23
histidinol dehydrogenase
|
–
|
|
BRENDA:
BS371011
KEGG:
R03012
MetaCyc:
HISTOLDEHYD-RXN
|
|
|
|
H+ + L-pyrroline-5-carboxylate + malonyl-CoA + H2O <=> (2S,5S)-5-carboxymethylproline + CoA + CO2
|
2.3.1.226
carboxymethylproline synthase
|
–
|
|
BRENDA:
BR50641
KEGG:
R10485
MetaCyc:
RXN-8947
SABIO-RK:
7117
|
|
|
|
meso-2,6-diaminoheptanedioate + NADP+ + H2O <=> L-2-amino-6-oxopimelate + NH3 + NADPH + H+
|
1.4.1.16
diaminopimelate dehydrogenase
|
–
|
|
BRENDA:
BR36864
KEGG:
R02755
MetaCyc:
DIAMINOPIMELATE-DEHYDROGENASE-RXN
|
|
|
|
L-Histidinol_phosphate + H2O <=> L-Histidinol + phosphate
|
3.1.3.15
histidinol-phosphatase
3.1.3.2
acid phosphatase
|
–
–
|
|
BRENDA:
BR19199
KEGG:
R03013
MetaCyc:
HISTIDPHOS-RXN
|
|
|
|
Premithramycin_B + NADPH + H+ + O2 <=> Mithramycin_DK + NADP+ + CO2
|
1.14.13
|
–
|
|
KEGG:
R09353
|
|
|
|
(9Z)-(13S)-12,13-epoxyoctadeca-9,11,15-trienoate + H2O <=> 9-Hydroxy-12-oxo-10(E),15(Z)-octadecadienoic_acid
|
not assigned
|
–
|
|
KEGG:
R12140
|
|
|
|
3-Hydroxy-OPC8-CoA + NAD+ <=> 3-Oxo-OPC8-CoA + NADH + H+
|
1.1.1.211
long-chain-3-hydroxyacyl-CoA dehydrogenase
1.1.1.35
3-hydroxyacyl-CoA dehydrogenase
|
–
–
|
|
KEGG:
R07890
|
|
|
|
anabasine + CO2 <=> DELTA1-piperideine + nicotinate
|
not assigned
|
–
|
|
KEGG:
R05128
|
|
|
|
N,N-dihydroxy-L-phenylalanine + H+ <=> (E)-phenylacetaldoxime + CO2 + H2O
|
1.14.14.40
phenylalanine N-monooxygenase
|
–
|
|
BRENDA:
BR49592
KEGG:
R09581
MetaCyc:
RXN-12068
|
|
|
|
4,21-Dehydrogeissoschizine <=> 19-epi-Cathenamine
|
not assigned
|
–
|
|
KEGG:
R05873
|
|
|
|
S-adenosyl-L-methionine + gamma-tocotrienol <=> S-adenosyl-L-homocysteine + alpha-tocotrienol + H+
|
2.1.1.95
tocopherol C-methyltransferase
|
–
|
|
BRENDA:
BR52801
KEGG:
R10491
MetaCyc:
RXN-14918
|
|
|
|
UDP-glucose + Vomilenine <=> H+ + Raucaffricine + UDP
|
2.4.1.219
vomilenine glucosyltransferase
|
–
|
|
BRENDA:
BR44195
KEGG:
R05882
MetaCyc:
2.4.1.219-RXN
|
|
|
|
chanoclavine-I + NAD+ <=> chanoclavine-I_aldehyde + NADH + H+
|
1.1.1.332
chanoclavine-I dehydrogenase
|
–
|
|
BRENDA:
BR50141
KEGG:
R10128
MetaCyc:
RXN-13468
SABIO-RK:
14853
|
|
|
|
Narcotoline + S-adenosyl-L-methionine <=> noscapine + S-adenosyl-L-homocysteine
|
2.1.1.352
3-O-acetyl-4'-O-demethylpapaveroxine 4'-O-methyltransferase
|
–
|
|
KEGG:
R12262
|
|
|
|
3-phospho-D-glycerate + NAD+ <=> H+ + 3-phosphohydroxypyruvate + NADH
|
1.1.1.95
phosphoglycerate dehydrogenase
|
–
|
|
BRENDA:
BR29351;
BS188712
KEGG:
R01513
MetaCyc:
PGLYCDEHYDROG-RXN
SABIO-RK:
1684;
8970
|
|
|
|
D-glucose_6-phosphate <=> D-myo-Inositol_1-phosphate
|
5.5.1.4
inositol-3-phosphate synthase
|
–
|
|
BRENDA:
BR262
KEGG:
R07324
MetaCyc:
MYO-INOSITOL-1-PHOSPHATE-SYNTHASE-RXN
SABIO-RK:
1181
|
|
|
|
Neoabietal <=> Neoabietic_acid
|
not assigned
|
–
|
|
KEGG:
R06359
|
|
|
|
bilirubin + O2 <=> Biliverdin + H2O
|
1.3.3.5
bilirubin oxidase
|
–
|
|
BRENDA:
BR36841
KEGG:
R02394
MetaCyc:
BILIRUBIN-OXIDASE-RXN
SABIO-RK:
2335
|
|
|
|
strictosidine + H2O <=> strictosidine_aglycone + D-glucose
|
3.2.1.105
3alpha(S)-strictosidine beta-glucosidase
3.2.1.125
raucaffricine beta-glucosidase
|
–
–
|
|
BRENDA:
BR15979
KEGG:
R03820
MetaCyc:
STRICTOSIDINE-BETA-GLUCOSIDASE-RXN
|
|
|
|
(2Z,6E)-farnesyl_diphosphate + isopentenyl_diphosphate <=> (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E)-decaprenyl_diphosphate + diphosphate
|
2.5.1.86
trans,polycis-decaprenyl diphosphate synthase
|
–
|
|
BRENDA:
BR49317
KEGG:
R09244
MetaCyc:
RXN-11023
|
|
|
|
beta-D-glucose_6-phosphate + NADP+ <=> 6-phospho-D-glucono-1,5-lactone + NADPH
|
1.1.1.363
glucose-6-phosphate dehydrogenase [NAD(P)+]
1.1.1.47
glucose 1-dehydrogenase [NAD(P)+]
1.1.1.49
glucose-6-phosphate dehydrogenase (NADP+)
|
–
–
–
|
|
BRENDA:
BS355829;
BS355830
KEGG:
R02736
SABIO-RK:
18
|
|
|
|
N,N-dihydroxy-L-valine + H+ <=> (E)-2-methylpropanal-oxime + CO2 + H2O
|
1.14.14.38
valine N-monooxygenase
1.14.14.39
isoleucine N-monooxygenase
|
–
–
|
|
BRENDA:
BR49383
KEGG:
R10033
MetaCyc:
RXN-5065
|
|
|
|
8-demethyltetracenomycin_C + dTDP-L-rhamnose <=> 8-demethyl-8-alpha-L-rhamnosyl_tetracenomycin_C + dTDP + H+
|
2.4.1.331
8-demethyltetracenomycin C L-rhamnosyltransferase
|
–
|
|
BRENDA:
BR50871
KEGG:
R10955
MetaCyc:
RXN-15406
|
|
|
|
3-O-acetylpapaveroxine + H2O <=> Papaveroxine + acetate
|
3.1.1.105
3-O-acetylpapaveroxine carboxylesterase
|
–
|
|
KEGG:
R11693
|
|
|
|
S-adenosyl-L-methionine + demethylphylloquinol <=> vitamin_KH2 + S-adenosyl-L-homocysteine + H+
|
2.1.1.329
demethylphylloquinol methyltransferase
|
–
|
|
BRENDA:
BR51848
KEGG:
R04994
MetaCyc:
RXN-7569
|
|
|
|
H+ + AMP + H2O <=> IMP + NH3
|
3.5.4.17
adenosine-phosphate deaminase
3.5.4.4
adenosine deaminase
3.5.4.6
AMP deaminase
3.5.4.7
ADP deaminase
|
–
–
–
–
|
|
BRENDA:
BR22743
KEGG:
R00181
MetaCyc:
AMP-DEAMINASE-RXN
SABIO-RK:
135
|
|
|
|
L-cystathionine + H2O <=> L-homocysteine + pyruvate + NH3
|
2.5.1.48
cystathionine gamma-synthase
3.5.1.61
mimosinase
4.2.1.22
cystathionine beta-synthase
4.4.1.1
cystathionine gamma-lyase
4.4.1.13
cysteine-S-conjugate beta-lyase
4.4.1.28
L-cysteine desulfidase
4.4.1.3
dimethylpropiothetin dethiomethylase
|
–
–
–
–
–
–
–
|
|
BRENDA:
BR3446
KEGG:
R01286
MetaCyc:
CYSTATHIONINE-BETA-LYASE-RXN
SABIO-RK:
1500;
1501
|
|
|
|
chlorophyllide_a + NADP+ <=> protochlorophyllide + NADPH + H+
|
1.3.1.33
protochlorophyllide reductase
|
–
|
|
BRENDA:
BR36964
KEGG:
R03845
SABIO-RK:
3597
|
|
|
|
arabidiol <=> (3S)-2,3-epoxy-2,3-dihydrosqualene + H2O
|
4.2.1.124
arabidiol synthase
|
–
|
|
BRENDA:
BR49623
KEGG:
R09700
MetaCyc:
RXN-9684
|
|
|
|
(S)-1-hydroxy-N-methylcanadine + reduced_flavodoxin + O2 <=> (13S,14R)-1,13-dihydroxy-N-methylcanadine + flavin + H2O
|
1.14.14.163
(S)-1-hydroxy-N-methylcanadine 13-hydroxylase
|
–
|
|
BRENDA:
BR52525
KEGG:
R11688
|
|
|
|
D-myo-Inositol_1-phosphate + H2O <=> myo-inositol + phosphate
|
3.1.3.11
fructose-bisphosphatase
3.1.3.2
acid phosphatase
3.1.3.23
sugar-phosphatase
3.1.3.25
inositol-phosphate phosphatase
3.1.3.26
4-phytase
3.1.3.57
inositol-1,4-bisphosphate 1-phosphatase
3.1.3.93
L-galactose 1-phosphate phosphatase
|
–
–
–
–
–
–
–
|
|
BRENDA:
BR26031
KEGG:
R01185;
R01187;
R07343
MetaCyc:
MYO-INOSITOL-1OR-4-MONOPHOSPHATASE-RXN;
RXN0-5408
SABIO-RK:
1422;
1424;
9216
|
|
|
|
geranylgeranyl_diphosphate <=> prephytoene_diphosphate + diphosphate
|
2.5.1.148
lycopaoctaene synthase
2.5.1.32
15-cis-phytoene synthase
|
–
–
|
|
BRENDA:
BR47500
KEGG:
R02065
MetaCyc:
2.5.1.32-RXN
SABIO-RK:
2081
|
|
|
|
L-arogenate + NADP+ <=> L-tyrosine + CO2 + NADPH
|
1.3.1.43
arogenate dehydrogenase
1.3.1.78
arogenate dehydrogenase (NADP+)
1.3.1.79
arogenate dehydrogenase [NAD(P)+]
|
–
–
–
|
|
BRENDA:
BR48485
KEGG:
R00733
MetaCyc:
RXN-14476;
RXN-5682
SABIO-RK:
1096
|
|
|
|
coniferyl_alcohol <=> Guaiacyl_lignin
|
1.11.1.21
catalase-peroxidase
1.11.1.7
peroxidase
|
–
–
|
|
KEGG:
R02596
|
|
|
|
2R,3R-2,3-dihydroxy-3-methylpentanoate <=> (S)-3-methyl-2-oxopentanoate + H2O
|
4.2.1.9
dihydroxy-acid dehydratase
|
–
|
|
BRENDA:
BS453486
KEGG:
R05070
MetaCyc:
DIHYDROXYMETVALDEHYDRAT-RXN
|
|
|
|
8,8a-deoxyoleandolide + 2 NADPH + 2 H+ + 2 O2 <=> Oleandolide + 2 NADP+ + 3 H2O
|
not assigned
|
–
|
|
KEGG:
R06454
|
|
|
|
heme + H+ <=> protoporphyrin_IX + Fe2+
|
4.99.1.1
protoporphyrin ferrochelatase
4.99.1.9
coproporphyrin ferrochelatase
|
–
–
|
|
BRENDA:
BR3454
KEGG:
R00310
MetaCyc:
PROTOHEMEFERROCHELAT-RXN
SABIO-RK:
802
|
|
|
|
geranyl_diphosphate + 2,4-dihydroxy-6-pentylbenzoate <=> cannabigerolate + diphosphate
|
2.5.1.102
geranyl-pyrophosphate---olivetolic acid geranyltransferase
|
–
|
|
BRENDA:
BR50302
KEGG:
R10176
MetaCyc:
RXN-7853
|
|
|
|
(R)-mevalonate + ATP <=> H+ + (R)-5-phosphomevalonate + ADP
|
2.7.1.36
mevalonate kinase
|
–
|
|
BRENDA:
BR47775
KEGG:
R02245
MetaCyc:
MEVALONATE-KINASE-RXN
SABIO-RK:
2215
|
|
|
|
S-adenosyl-L-methionine + 1-(3,4-Dihydroxyphenyl)-5-hydroxy-3-decanone <=> [6]-gingerol + S-adenosyl-L-homocysteine + H+
|
2.1.1
|
–
|
|
KEGG:
R08804
MetaCyc:
RXN-12527
|
|
|
|
(9Z,11E,13S,15Z)-13-hydroperoxy-9,11,15-octadecatrienoate <=> H2O + (9Z)-(13S)-12,13-epoxyoctadeca-9,11,15-trienoate
|
4.2.1.92
hydroperoxide dehydratase
|
–
|
|
BRENDA:
BR48341;
BS363380
KEGG:
R07863
MetaCyc:
RXN1F-19
|
|
|
|
3,6-Dihydronicotinic_acid <=> 3,6-Dihydropyridine
|
not assigned
|
–
|
|
KEGG:
R09051
|
|
|
|
malonyl-CoA + cinnamoyl-CoA + H+ <=> CoA + pinosylvin + CO2
|
2.3.1.146
pinosylvin synthase
2.3.1.95
trihydroxystilbene synthase
|
–
–
|
|
BRENDA:
BR47494
KEGG:
R02505
MetaCyc:
PINOSYLVIN-SYNTHASE-RXN
SABIO-RK:
2432
|
|
|
|
heme + (2E,6E)-farnesyl_diphosphate + H2O <=> heme_O + diphosphate
|
2.5.1.141
heme o synthase
|
–
|
|
BRENDA:
BS427516
KEGG:
R07411
|
|
|
|
geranylgeranyl_diphosphate <=> terpentedienyl_diphosphate
|
5.5.1.15
terpentedienyl-diphosphate synthase
|
–
|
|
BRENDA:
BR48916
KEGG:
R09714
MetaCyc:
RXN-9456
|
|
|
|
(S)-2,3,4,5-tetrahydropyridine-2-carboxylate <=> L-pipecolic_acid
|
not assigned
|
–
|
|
KEGG:
R08414
|
|
|
|
5-Oxoavermectin_''''1a''''_aglycone + NADPH + H+ <=> Avermectin_B1a_aglycone + NADP+
|
not assigned
|
–
|
|
KEGG:
R06473
|
|
|
|
16-methoxy-2,3-dihydro-3-hydroxytabersonine + acceptor <=> (3R)-3-hydroxy-16-methoxy-1,2-didehydro-2,3-dihydrotabersonine + reduced_acceptor
|
1.1.99.41
3-hydroxy-1,2-didehydro-2,3-dihydrotabersonine reductase
|
–
|
|
BRENDA:
BR52126
KEGG:
R11777
MetaCyc:
RXN-18618
|
|
|
|
copalyl_diphosphate <=> diphosphate + abieta-7,13-diene
|
4.2.3.18
abieta-7,13-diene synthase
|
–
|
|
BRENDA:
BR49933
KEGG:
R06301
MetaCyc:
4.2.3.18-RXN
|
|
|
|
beta-D-fructose_6-phosphate + diphosphate <=> H+ + phosphate + D-fructose_1,6-bisphosphate
|
2.7.1.90
diphosphate---fructose-6-phosphate 1-phosphotransferase
|
–
|
|
BRENDA:
BR47815
KEGG:
R00764;
R02073
MetaCyc:
2.7.1.90-RXN
SABIO-RK:
1119;
14403
|
|
|
|
H+ + alpha-D-glucose_1-phosphate + ATP <=> ADP-glucose + diphosphate
|
2.7.7.24
glucose-1-phosphate thymidylyltransferase
2.7.7.27
glucose-1-phosphate adenylyltransferase
2.7.7.9
UTP---glucose-1-phosphate uridylyltransferase
|
–
–
–
|
|
BRENDA:
BR47873
KEGG:
R00948
MetaCyc:
GLUC1PADENYLTRANS-RXN
SABIO-RK:
1262;
9396
|
|
|
|
S-adenosyl-L-methionine + L-homocysteine <=> L-methionine + S-adenosyl-L-homocysteine + H+
|
2.1.1.10
homocysteine S-methyltransferase
2.1.1.13
methionine synthase
2.1.1.14
5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
2.1.1.280
selenocysteine Se-methyltransferase
|
–
–
–
–
|
|
BRENDA:
BS289526;
BS419713
KEGG:
R00650
MetaCyc:
HOMOCYSTEINE-S-METHYLTRANSFERASE-RXN
SABIO-RK:
1035
|
|
|
|
Fumiquinazoline_A + O2 <=> Fumiquinazoline_C + H2O2
|
1.5.3
|
–
|
|
KEGG:
R12420
MetaCyc:
RXN-15749
|
|
|
|
8 malonyl-CoA + [acyl-carrier_protein] <=> 3,5,7,9,11,13,15-Heptaoxo-hexadecanoyl-[acp] + 8 CO2 + 8 CoA
|
2.3.1
|
–
|
|
KEGG:
R09258
|
|
|
|
tabersonine <=> Minovincinine
|
not assigned
|
–
|
|
KEGG:
R05869
|
|
|
|
L-ornithine <=> L-proline + NH3
|
4.3.1.12
ornithine cyclodeaminase
|
–
|
|
BRENDA:
BR3424
KEGG:
R00671
MetaCyc:
ORNITHINE-CYCLODEAMINASE-RXN
SABIO-RK:
1051
|
|
|
|
Avermectin_B1b_aglycone + S-adenosyl-L-methionine <=> Avermectin_A1b_aglycone + S-adenosyl-L-homocysteine
|
2.1.1
|
–
|
|
KEGG:
R06479
|
|
|
|
L-Tyrosyl-[pcp] + O2 <=> beta-Hydroxy-L-tyrosyl-[pcp] + H2O
|
not assigned
|
–
|
|
KEGG:
R06752
|
|
|
|
L-lysine + H+ <=> cadaverine + CO2
|
4.1.1.17
ornithine decarboxylase
4.1.1.18
lysine decarboxylase
4.1.1.19
arginine decarboxylase
4.1.1.50
adenosylmethionine decarboxylase
4.1.1.86
diaminobutyrate decarboxylase
4.1.1.B12
|
–
–
–
–
–
–
|
|
BRENDA:
BR6435
KEGG:
R00462
MetaCyc:
LYSDECARBOX-RXN
SABIO-RK:
899
|
|
|
|
amylose + phosphate <=> amylose + alpha-D-glucose_1-phosphate
|
2.4.1.1
glycogen phosphorylase
|
–
|
|
BRENDA:
BR44131;
BS321850;
BS321851;
BS321852;
BS389786
KEGG:
R01821;
R02111;
R06050;
R06185
MetaCyc:
RXN-12171;
RXN0-5184
SABIO-RK:
2101
|
|
|
|
4alpha-methyl-5alpha-ergosta-8,24-dien-3beta-ol + NADP+ <=> 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + NADPH + H+
|
1.3.1.70
Delta14-sterol reductase
|
–
|
|
BRENDA:
BS370809
KEGG:
R07483
MetaCyc:
RXN-4144
|
|
|
|
6''''''-deamino-6''''''-hydroxyneomycin_C + O2 <=> 6''''''-deamino-6''''''-oxoneomycin_C + H2O2
|
1.1.3.44
6'''-hydroxyneomycin C oxidase
|
–
|
|
BRENDA:
BR50144
KEGG:
R08902
MetaCyc:
RXN-13174
|
|
|
|
(3S,5S)-carbapenam_3-carboxylate + 2-oxoglutarate + O2 <=> (5R)-carbapen-2-em-3-carboxylate + succinate + CO2 + H2O
|
1.14.20
1.14.20.3
(5R)-carbapenem-3-carboxylate synthase
|
–
–
|
|
BRENDA:
BR50588
KEGG:
R10415
MetaCyc:
RXN-8949
|
|
|
|
paromomycin <=> 5''''''-epi-Lividomycin_B
|
not assigned
|
–
|
|
KEGG:
R11287
|
|
|
|
alpha-D-sedoheptulopyranose_7-phosphate <=> 2-epi-5-epi-valiolone + phosphate
|
4.2.3.152
2-epi-5-epi-valiolone synthase
|
–
|
|
BRENDA:
BR51246
KEGG:
R10937
MetaCyc:
RXN-9140
|
|
|
|
(10aS)-10,10a-dihydrophenazine-1-carboxylate <=> 5,10-dihydrophenazine_1-carboxylate
|
not assigned
|
–
|
|
KEGG:
R11576
MetaCyc:
RXN-17691
|
|
|
|
chorismate <=> 4-hydroxybenzoate + pyruvate
|
4.1.3.40
chorismate lyase
|
–
|
|
BRENDA:
BR48792
KEGG:
R01302
MetaCyc:
CHORPYRLY-RXN
|
|
|
|
gentamicin_X2 + FAD <=> 6''-Oxogentamicin_X2 + FADH2
|
not assigned
|
–
|
|
KEGG:
R11295
|
|
|
|
valienone_7-phosphate <=> validone_7-phosphate
|
not assigned
|
–
|
|
KEGG:
R11236
|
|
|
|
lycopene <=> delta-carotene
|
5.5.1.18
lycopene epsilon-cyclase
|
–
|
|
BRENDA:
BS415670
KEGG:
R06963
MetaCyc:
RXN1F-147
|
|
|
|
Paspalicine + O2 + NADPH + H+ <=> Paspalinine + NADP+ + H2O
|
1.14.13
|
–
|
|
KEGG:
R10362
|
|
|
|
(S)-8-oxocitronellyl_enol + NAD+ <=> (6E)-8-oxogeranial + NADH + H+
|
1.3.1.122
(S)-8-oxocitronellyl enol synthase
|
–
|
|
BRENDA:
BR52966-a
KEGG:
R12517
MetaCyc:
RXN-20745_WOP
|
|
|
|
Gibberellin_A53 + O2 + 2-oxoglutarate <=> gibberellin_44 + CO2 + succinate
|
1.14.11
1.14.11.12
gibberellin-44 dioxygenase
|
–
–
|
|
KEGG:
R05097
MetaCyc:
RXN1F-167
SABIO-RK:
4719
|
|
|
|
fumitremorgin_C + 2 reduced_flavodoxin + 2 O2 <=> 12alpha,13alpha-dihydroxyfumitremorgin_C + 2 flavin + 2 H2O
|
1.14.14.119
fumitremorgin C monooxygenase
|
–
|
|
BRENDA:
BR50576
KEGG:
R10414
|
|
|
|
argininosuccinate <=> L-arginine + fumarate
|
4.3.2.1
argininosuccinate lyase
4.3.2.2
adenylosuccinate lyase
|
–
–
|
|
BRENDA:
BR3431
KEGG:
R01086
MetaCyc:
ARGSUCCINLYA-RXN
SABIO-RK:
573
|
|
|
|
dihydrokaempferol + reduced_flavodoxin + O2 <=> dihydroquercetin + flavin + H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
1.14.14.82
flavonoid 3'-monooxygenase
|
–
–
|
|
BRENDA:
BS288544
KEGG:
R03124
|
|
|
|
(5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxylic_acid <=> (1R,6S)-6-amino-5-oxocyclohex-2-ene-1-carboxylate
|
5.3.3.17
trans-2,3-dihydro-3-hydroxyanthranilate isomerase
|
–
|
|
BRENDA:
BR49351
KEGG:
R09707
MetaCyc:
RXN-9031
|
|
|
|
5-epi-valiolone <=> valienone + H2O
|
4.2.1
|
–
|
|
KEGG:
R11233
MetaCyc:
RXN-9142
|
|
|
|
(2E,6E)-farnesyl_diphosphate <=> (3E,6E)-alpha-farnesene + diphosphate
|
4.2.3.46
alpha-farnesene synthase
|
–
|
|
BRENDA:
BR49095
KEGG:
R08696
MetaCyc:
RXN-8574
SABIO-RK:
13255
|
|
|
|
gentamicin_A + methylcobalamin + S-adenosyl-L-methionine + H+ + e- <=> gentamicin_X2 + Cobalamin + 5''-Deoxyadenosine + L-methionine
|
2.1.1
|
–
|
|
KEGG:
R11293
|
|
|
|
N-acetyldemethylphosphinothricin + methylcobalamin + S-adenosyl-L-methionine + H+ + e- <=> N-acetylphosphinothricin + Cobalamin + 5''-Deoxyadenosine + L-methionine
|
2.1.1.326
N-acetyldemethylphosphinothricin P-methyltransferase
|
–
|
|
KEGG:
R08873
|
|
|
|
kanamycin_A + NADP+ <=> 2''-dehydrokanamycin_A + NADPH + H+
|
1.1.1.355
2'-dehydrokanamycin reductase
|
–
|
|
BRENDA:
BR50592
KEGG:
R10417
MetaCyc:
RXN-14402
|
|
|
|
N-methylanthraniloyl-CoA + malonyl-CoA <=> CO2 + 1,3-dihydroxy-N-methylacridone + CoA
|
2.3.1.159
acridone synthase
|
–
|
|
BRENDA:
BR44008
KEGG:
R07250
MetaCyc:
2.3.1.159-RXN
|
|
|
|
UDP-glucose + 2-deoxystreptamine <=> 2''-deamino-2''-hydroxyparomamine + UDP + H+
|
2.4.1.284
2-deoxystreptamine glucosyltransferase
|
–
|
|
BRENDA:
BR50180
KEGG:
R10096
MetaCyc:
RXN-13121
|
|
|
|
versiconal_hemiacetal_acetate + H2O <=> versiconal + acetate
|
3.1.1.94
versiconal hemiacetal acetate esterase
|
–
|
|
BRENDA:
BR50545
KEGG:
R10401
MetaCyc:
RXN-9488
|
|
|
|
3beta-hydroxy-9beta-pimara-7,15-diene-19,6beta-olide + NADP+ <=> momilactone_A + NADPH + H+
|
1.1.1.295
momilactone-A synthase
|
–
|
|
BRENDA:
BR48879
KEGG:
R08917
MetaCyc:
RXN-9290
|
|
|
|
daidzein <=> Anhydroglycinol
|
not assigned
|
–
|
|
KEGG:
R07725
|
|
|
|
violaxanthin <=> neoxanthin
|
5.3.99.9
neoxanthin synthase
|
–
|
|
BRENDA:
BR48546
KEGG:
R06948
MetaCyc:
RXN1F-155
|
|
|
|
abieta-7,13-diene + reduced_flavodoxin + O2 <=> abietadienol + flavin + H2O
|
1.14.14.144
abieta-7,13-diene hydroxylase
|
–
|
|
BRENDA:
BR49044
KEGG:
R06351
|
|
|
|
UDP-glucose + amylose <=> UDP + starch
|
2.4.1.11
glycogen(starch) synthase
2.4.1.21
starch synthase (glycosyl-transferring)
2.4.1.242
NDP-glucose---starch glucosyltransferase
|
–
–
–
|
|
BRENDA:
BR44139;
BS321969;
BS410567
KEGG:
R00292;
R06051
|
|
|
|
Urdamycinone_F <=> Aquayamycin + H2O
|
not assigned
|
–
|
|
KEGG:
R06665
|
|
|
|
taxifolin + 2-oxoglutarate + O2 <=> quercetin + succinate + CO2 + H2O
|
1.14.20.4
anthocyanidin synthase
1.14.20.6
flavonol synthase
|
–
–
|
|
BRENDA:
BS371257;
BS373099
KEGG:
R02160
MetaCyc:
RXN-527
SABIO-RK:
2139
|
|
|
|
2''-deamino-2''-hydroxyneamine + UDP-alpha-D-kanosamine <=> kanamycin_A + UDP + H+
|
2.4.1.301
2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase
|
–
|
|
BRENDA:
BR50647
KEGG:
R10424
MetaCyc:
RXN-13125
|
|
|
|
N-(5-phospho-beta-D-ribosyl)anthranilate <=> 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate
|
5.3.1.24
phosphoribosylanthranilate isomerase
|
–
|
|
BRENDA:
BR48377
KEGG:
R03509
MetaCyc:
PRAISOM-RXN
SABIO-RK:
15372
|
|
|
|
vitamin_D3 + reduced_ferredoxin_[iron-sulfur]_cluster + O2 + H+ <=> 25-hydroxyvitamin_D3 + oxidized_ferredoxin + H2O
|
1.14.15.22
vitamin D 1,25-hydroxylase
|
–
|
|
BRENDA:
BR51834
KEGG:
R11458
MetaCyc:
RXN-18214
|
|
|
|
UDP-glucose + quercetin <=> UDP + quercetin_3-O-glucoside + H+
|
2.4.1.115
anthocyanidin 3-O-glucosyltransferase
2.4.1.177
cinnamate beta-D-glucosyltransferase
2.4.1.35
phenol beta-glucosyltransferase
2.4.1.357
phlorizin synthase
2.4.1.91
flavonol 3-O-glucosyltransferase
|
–
–
–
–
–
|
|
BRENDA:
BS323087;
BS445961
KEGG:
R02158
MetaCyc:
RXN1F-462
SABIO-RK:
13061
|
|
|
|
NADP+ + (+)-neomenthol <=> H+ + NADPH + (-)-menthone
|
1.1.1.208
(+)-neomenthol dehydrogenase
|
–
|
|
BRENDA:
BR33669
KEGG:
R02548
MetaCyc:
+-NEOMENTHOL-DEHYDROGENASE-RXN
SABIO-RK:
2463
|
|
|
|
UDP-3-ketoglucose + L-glutamate <=> UDP-alpha-D-kanosamine + 2-oxoglutarate
|
2.6.1
|
–
|
|
KEGG:
R06586
|
|
|
|
Anhydroglycinol <=> coumestrol
|
not assigned
|
–
|
|
KEGG:
R07726
MetaCyc:
RXN-11643
|
|
|
|
Strigolactone_ABC-rings <=> 5-Deoxystrigol
|
not assigned
|
–
|
|
KEGG:
R08989
|
|
|
|
3''-phosphoadenylyl-sulfate + desulfo-indol-3-yl-methyl_glucosinolate <=> adenosine_3,5''-bisphosphate + glucobrassicin + H+
|
2.8.2.24
aromatic desulfoglucosinolate sulfotransferase
2.8.2.38
aliphatic desulfoglucosinolate sulfotransferase
|
–
–
|
|
BRENDA:
BR52177;
BS407937
KEGG:
R08167
MetaCyc:
RXN-1443
|
|
|
|
L-aspartate + 2-oxoglutarate <=> oxaloacetate + L-glutamate
|
2.6.1.1
aspartate transaminase
2.6.1.19
4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.2
alanine transaminase
2.6.1.39
2-aminoadipate transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.5
tyrosine transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.75
cysteine-conjugate transaminase
2.6.1.78
aspartate---prephenate aminotransferase
2.6.1.79
glutamate---prephenate aminotransferase
|
–
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BR47671;
BS377429
KEGG:
R00355
MetaCyc:
ASPAMINOTRANS-RXN;
RXN-13697
SABIO-RK:
825
|
|
|
|
L-aspartate + L-citrulline + ATP <=> H+ + argininosuccinate + diphosphate + AMP
|
6.3.4.5
argininosuccinate synthase
|
–
|
|
BRENDA:
BR142;
BS408483
KEGG:
R01954
MetaCyc:
ARGSUCCINSYN-RXN
SABIO-RK:
572
|
|
|
|
echinenone + reduced_acceptor + O2 <=> canthaxanthin + acceptor + H2O
|
1.14.99.63
beta-carotene 4-ketolase
|
–
|
|
BRENDA:
BR52477
KEGG:
R07563
MetaCyc:
RXN-8185
|
|
|
|
phosphatidylethanolamine + L-serine <=> phosphatidylserine + ethanolamine
|
2.7.8.29
L-serine-phosphatidylethanolamine phosphatidyltransferase
|
–
|
|
BRENDA:
BR49243
KEGG:
R07376
MetaCyc:
RXN-1382
|
|
|
|
(+)-dihydrokaempferol + 2-oxoglutarate + O2 <=> kaempferol + succinate + CO2 + H2O + H+
|
1.14.20.5
flavone synthase I
1.14.20.6
flavonol synthase
|
–
–
|
|
BRENDA:
BS371221;
BS373078
KEGG:
R03126
MetaCyc:
RXN1F-93
|
|
|
|
S-adenosyl-L-methionine + jasmonic_acid <=> S-adenosyl-L-homocysteine + methyl_jasmonate
|
2.1.1.141
jasmonate O-methyltransferase
2.1.1.274
salicylate 1-O-methyltransferase
2.1.1.B126
|
–
–
–
|
|
BRENDA:
BR48123
KEGG:
R05759
MetaCyc:
RXN-10768
SABIO-RK:
5352
|
|
|
|
NADP+ + codeine <=> H+ + NADPH + codeinone
|
1.1.1.218
morphine 6-dehydrogenase
1.1.1.247
codeinone reductase (NADPH)
|
–
–
|
|
BRENDA:
BR916
KEGG:
R05124
MetaCyc:
1.1.1.247-RXN
SABIO-RK:
4745
|
|
|
|
(R)-reticuline + reduced_flavodoxin + O2 <=> salutaridine + flavin + 2 H2O
|
1.14.19.67
salutaridine synthase
|
–
|
|
BRENDA:
BR36966
KEGG:
R04696
|
|
|
|
(2E,6E)-farnesyl_diphosphate <=> gamma-humulene + diphosphate
|
4.2.3.56
gamma-humulene synthase
|
–
|
|
BRENDA:
BR49427
KEGG:
R08540
MetaCyc:
RXN-8541
|
|
|
|
pentalenolactone_D + 2-oxoglutarate + O2 <=> pentalenolactone_F + succinate + CO2 + H2O
|
1.14.11.36
pentalenolactone F synthase
|
–
|
|
BRENDA:
BR50258
KEGG:
R10145
MetaCyc:
RXN-13751
|
|
|
|
5 ATP + 3 L-4-hydroxyphenylglycine + L-arginine + L-serine + H2O <=> 5 AMP + 5 diphosphate + nocardicin_G + L-4-Hydroxyphenylglycyl-L-arginine
|
not assigned
|
–
|
|
KEGG:
R10880
|
|
|
|
siroheme + H+ <=> 12,18-didecarboxysiroheme + CO2
|
4.1.1.111
siroheme decarboxylase
|
–
|
|
BRENDA:
BR51140
KEGG:
R12000
MetaCyc:
RXN-15805
|
|
|
|
ethanol + 2 ferricytochrome_b5 <=> acetaldehyde + 2 ferricytochrome_b5
|
1.1.2.7
methanol dehydrogenase (cytochrome c)
|
–
|
|
BRENDA:
BS449899
KEGG:
R09127
|
|
|
|
violaxanthin <=> 9-cis-violaxanthin
|
not assigned
|
–
|
|
KEGG:
R06950
|
|
|
|
geranylgeranyl_diphosphate + isopentenyl_diphosphate <=> nonaprenyl_diphosphate + diphosphate
|
2.5.1.84
all-trans-nonaprenyl diphosphate synthase [geranyl-diphosphate specific]
2.5.1.85
all-trans-nonaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]
|
–
–
|
|
BRENDA:
BR49315
KEGG:
R09251
MetaCyc:
RXN-11486
|
|
|
|
neamine + UDP-alpha-D-kanosamine <=> kanamycin_B + UDP + H+
|
2.4.1.301
2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase
|
–
|
|
BRENDA:
BR50648
KEGG:
R10425
MetaCyc:
RXN-13147
|
|
|
|
cyclooctat-9-ene-5,7-diol + O2 + reduced_acceptor <=> cyclooctatin + H2O + acceptor
|
1.14.99.62
cyclooctatin synthase
|
–
|
|
BRENDA:
BR52475
KEGG:
R12178
MetaCyc:
RXN-15430
|
|
|
|
N-Demethylnarwedine + NADPH <=> Norgalanthamine + NADP+
|
1.1.1
|
–
|
|
KEGG:
R08442
|
|
|
|
H+ + H2O + Beta-cyanoalanine <=> NH3 + L-aspartate
|
3.5.5.4
cyanoalanine nitrilase
|
–
|
|
BRENDA:
BR48303
KEGG:
R00486
MetaCyc:
3.5.5.4-RXN
SABIO-RK:
918
|
|
|
|
NAD+ + morphine <=> NADH + morphinone + H+
|
1.1.1.218
morphine 6-dehydrogenase
1.1.1.239
3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
|
–
–
|
|
BRENDA:
BR29259-a
KEGG:
R03591
MetaCyc:
MORPHINE-6-DEHYDROGENASE-RXN_WOP
SABIO-RK:
3374
|
|
|
|
benzoate + NADPH + O2 <=> salicylate + NADP+ + H2O
|
1.14.13
|
–
|
|
KEGG:
R08838
|
|
|
|
Gibberellin_A24 <=> gibberellin_a9 + CO2
|
1.14.11.12
gibberellin-44 dioxygenase
|
–
|
|
KEGG:
R06326
SABIO-RK:
5908
|
|
|
|
spheroiden-2-one + H2O <=> Hydroxyspheroidenone
|
4.2.1.131
carotenoid 1,2-hydratase
|
–
|
|
KEGG:
R07539
|
|
|
|
dTDP-L-rhamnose + NADP+ <=> dTDP-4-dehydro-beta-L-rhamnose + NADPH + H+
|
1.1.1.133
dTDP-4-dehydrorhamnose reductase
|
–
|
|
BRENDA:
BR29200
KEGG:
R02777
MetaCyc:
DTDPDEHYRHAMREDUCT-RXN
|
|
|
|
N1,N5,N10-Tri(hydroxyferuloyl)_spermidine + S-adenosyl-L-methionine <=> N1,N5-Di(hydroxyferuloyl)-N10-sinapoyl_spermidine + S-adenosyl-L-homocysteine
|
2.1.1
|
–
|
|
KEGG:
R08987
|
|
|
|
5-dehydroepisterol + NADPH + H+ + O2 <=> ergosta-5,7,22,24(28)-tetraen-3beta-ol + NADP+ + 2 H2O
|
1.14.19.41
sterol 22-desaturase
|
–
|
|
BRENDA:
BR51505;
BS432793
KEGG:
R07506
|
|
|
|
(R)-mevalonate + NAD+ + CoA <=> (S)-3-hydroxy-3-methylglutaryl-CoA + NADH + H+
|
1.1.1.34
hydroxymethylglutaryl-CoA reductase (NADPH)
1.1.1.88
hydroxymethylglutaryl-CoA reductase
1.1.1.B38
|
–
–
–
|
|
BRENDA:
BR29347;
BR50597-a;
BS188686
KEGG:
R02081
MetaCyc:
HYDROXYMETHYLGLUTARYL-COA-REDUCTASE-RXN
SABIO-RK:
6923
|
|
|
|
(S)-3-methyl-2-oxopentanoate + Enzyme_N6-(lipoyl)lysine <=> [dihydrolipoyllysine-residue_(2-methylpropanoyl)transferase]_S-(2-methylbutanoyl)dihydrolipoyllysine + CO2
|
1.2.4.4
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
|
–
|
|
KEGG:
R04225
|
|
|
|
4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + O2 + ferricytochrome_b5 + H+ <=> 4alpha-carboxy-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol + ferricytochrome_b5 + H2O
|
1.14.18.9
4alpha-methylsterol monooxygenase
|
–
|
|
KEGG:
R07509
MetaCyc:
RXN-13712
|
|
|
|
S-adenosyl-L-methionine + (-)-pluviatolide <=> S-adenosyl-L-homocysteine + (-)-bursehernin + H+
|
2.1.1.323
(-)-pluviatolide 4-O-methyltransferase
|
–
|
|
BRENDA:
BR51592
KEGG:
R11230
MetaCyc:
RXN-16361
|
|
|
|
Roquefortine_C + 2 reduced_flavodoxin + 2 O2 <=> Glandicoline_A + 2 flavin + 3 H2O
|
1.14.14
|
–
|
|
KEGG:
R12441
|
|
|
|
3-Amino-4,7-dihydroxy-8-chlorocoumarin + 3-dimethylallyl-4-hydroxybenzoate <=> Chlorobiocic_acid
|
not assigned
|
–
|
|
KEGG:
R06776
|
|
|
|
S-adenosyl-L-methionine + naringenin <=> H+ + isosakuranetin + S-adenosyl-L-homocysteine
|
2.1.1.231
flavonoid 4'-O-methyltransferase
|
–
|
|
BRENDA:
BS415301
KEGG:
R12213
MetaCyc:
RXN-7777
|
|
|
|
(3Z)-phycoerythrobilin + oxidized_ferredoxin <=> 15,16-dihydrobiliverdin + reduced_ferredoxin_[iron-sulfur]_cluster + H+
|
1.3.7.3
phycoerythrobilin:ferredoxin oxidoreductase
|
–
|
|
BRENDA:
BR40343
KEGG:
R05819
MetaCyc:
1.3.7.3-RXN
|
|
|
|
Polyphosphate + beta-D-glucose <=> Polyphosphate + beta-D-glucose_6-phosphate
|
2.7.1.63
polyphosphate---glucose phosphotransferase
|
–
|
|
KEGG:
R02187
|
|
|
|
5-amino-5-deoxy-3-dehydroshikimate <=> H+ + 3-amino-5-hydroxybenzoate + H2O
|
4.2.1.144
3-amino-5-hydroxybenzoate synthase
|
–
|
|
BRENDA:
BR50552
KEGG:
R06595
MetaCyc:
RXN-9587
|
|
|
|
geranylgeranyl_diphosphate + indole-3-glycerol_phosphate <=> 3-Geranylgeranylindole + D-glyceraldehyde_3-phosphate + diphosphate
|
not assigned
|
–
|
|
KEGG:
R10349
MetaCyc:
RXN-15494
|
|
|
|
(-)-limonene + reduced_flavodoxin + O2 <=> (S)-perillyl_alcohol + flavin + H2O
|
1.14.14.52
(S)-limonene 7-monooxygenase
|
–
|
|
BRENDA:
BR36765
KEGG:
R02470
|
|
|
|
ferulic_acid + ATP + CoA <=> feruloyl-CoA + AMP + diphosphate
|
6.2.1.12
4-coumarate---CoA ligase
6.2.1.34
trans-feruloyl-CoA synthase
|
–
–
|
|
BRENDA:
BS27
KEGG:
R02194
MetaCyc:
6.2.1.34-RXN
SABIO-RK:
2167
|
|
|
|
11-hydroxyferruginol + reduced_flavodoxin + O2 <=> 11,20-dihydroxyferruginol + flavin + H2O
|
1.14.14.67
11-hydroxysugiol 20-monooxygenase
|
–
|
|
BRENDA:
BS442718
KEGG:
R11987
|
|
|
|
10-formyltetrahydrofolate + 5-aminoimidazole-4-carboxamide_ribonucleotide <=> tetrahydrofolate + 5-Formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide
|
2.1.2.3
phosphoribosylaminoimidazolecarboxamide formyltransferase
|
–
|
|
BRENDA:
BR43942
KEGG:
R04560
MetaCyc:
AICARTRANSFORM-RXN
SABIO-RK:
122
|
|
|
|
geranylgeranyl_diphosphate + H2O <=> cyclooctat-9-en-7-ol + diphosphate
|
4.2.3.146
cyclooctat-9-en-7-ol synthase
|
–
|
|
BRENDA:
BR51060
KEGG:
R10763
MetaCyc:
RXN-15429
|
|
|
|
shikimate + pyrroloquinoline_quinone <=> 3-dehydroshikimate + reduced_pyrroloquinoline_quinone
|
1.1.5.8
quinate dehydrogenase (quinone)
|
–
|
|
KEGG:
R02415
|
|
|
|
antheraxanthin + reduced_ferredoxin_[iron-sulfur]_cluster + H+ + O2 <=> violaxanthin + oxidized_ferredoxin + H2O
|
1.14.15.21
zeaxanthin epoxidase
|
–
|
|
BRENDA:
BR48605
KEGG:
R06947
MetaCyc:
RXN-7979
|
|
|
|
Antibiotic_JI-20B <=> Antibiotic_JI-20Ba
|
not assigned
|
–
|
|
KEGG:
R11301
|
|
|
|
Terpendole_B <=> 13-Desoxyterpendole_I
|
not assigned
|
–
|
|
KEGG:
R10571
|
|
|
|
phytyl_diphosphate + homogentisate + H+ <=> 2-methyl-6-phytylbenzene-1,4-diol + CO2 + diphosphate
|
2.5.1.115
homogentisate phytyltransferase
|
–
|
|
BRENDA:
BR50958
KEGG:
R07500
MetaCyc:
RXN-2541
|
|
|
|
ATP + L-aspartate + NH3 <=> diphosphate + AMP + L-asparagine + H+
|
6.3.1.1
aspartate---ammonia ligase
6.3.5.4
asparagine synthase (glutamine-hydrolysing)
|
–
–
|
|
BRENDA:
BR93
KEGG:
R00483
MetaCyc:
ASNSYNA-RXN
|
|
|
|
7beta-(5-D-Aminoadipamido)-3-carbamoyloxymethylceph-3-em-4-carboxylic_acid + 2-oxoglutarate + O2 <=> 7a-Hydroxy-O-carbamoyl-deacetylcephalosporin_C + succinate + CO2
|
not assigned
|
–
|
|
KEGG:
R05302
|
|
|
|
kanosamine_6-phosphate <=> Aminofructose_6-phosphate
|
5.3.1
|
–
|
|
KEGG:
R06589
MetaCyc:
RXN-9582
|
|
|
|
dimethylallyl_diphosphate + oxidized_ferredoxin + H2O <=> (E)-4-hydroxy-3-methylbut-2-en-1-yl_diphosphate + reduced_ferredoxin_[iron-sulfur]_cluster + H+
|
1.17.7.4
4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase
|
–
|
|
BRENDA:
BR49868
KEGG:
R08210
MetaCyc:
RXN0-884
|
|
|
|
Demethyl-desacetyl-rifamycin_S <=> 27-O-Demethyl-25-O-desacetylrifamycin_SV
|
not assigned
|
–
|
|
KEGG:
R06996
|
|
|
|
UDP-alpha-D-kanosamine + nebramine <=> UDP + tobramycin
|
2.4.1
|
–
|
|
KEGG:
R11278
|
|
|
|
cinnamaldehyde + CoA + NADP+ <=> cinnamoyl-CoA + NADPH + H+
|
1.2.1.44
cinnamoyl-CoA reductase
|
–
|
|
BRENDA:
BR29404
KEGG:
R02506
MetaCyc:
CINNAMOYL-COA-REDUCTASE-RXN
|
|
|
|
diacylglycerol + CDP-ethanolamine <=> phosphatidylethanolamine + CMP + H+
|
2.7.8.1
ethanolaminephosphotransferase
2.7.8.2
diacylglycerol cholinephosphotransferase
|
–
–
|
|
BRENDA:
BR47990
KEGG:
R02057
MetaCyc:
ETHANOLAMINEPHOSPHOTRANSFERASE-RXN
SABIO-RK:
2074
|
|
|
|
H2O + pyruvate + ATP <=> H+ + phosphate + phosphoenolpyruvate + AMP
|
2.7.1.40
pyruvate kinase
2.7.9.2
pyruvate, water dikinase
|
–
–
|
|
BRENDA:
BR48097
KEGG:
R00199
MetaCyc:
PEPSYNTH-RXN
SABIO-RK:
148
|
|
|
|
2-Hydroxy-beta-keto-L-tyrosyl-[pcp] <=> 3-amino-4,7-dihydroxycoumarin
|
not assigned
|
–
|
|
KEGG:
R06765
|
|
|
|
gamma-tocopherol <=> 2,3-dimethyl-6-phytylbenzene-1,4-diol
|
5.5.1.24
tocopherol cyclase
|
–
|
|
BRENDA:
BR50792
KEGG:
R07502
MetaCyc:
RXN-2543
|
|
|
|
cis-Zeatin_riboside_monophosphate + H2O <=> cis-Zeatin_riboside + phosphate
|
not assigned
|
–
|
|
KEGG:
R08079
MetaCyc:
RXN-4542
|
|
|
|
ATP + Tabtoxinine-beta-lactam + L-threonine <=> ADP + phosphate + Tabtoxin
|
6.3.2
|
–
|
|
KEGG:
R10892
|
|
|
|
squalene + 2 ferricytochrome_b5 + O2 + 2 H+ <=> (3S)-2,3-epoxy-2,3-dihydrosqualene + 2 ferricytochrome_b5 + H2O
|
1.14.19
|
–
|
|
KEGG:
R12355
|
|
|
|
LL-2,6-Diaminoheptanedioate <=> meso-2,6-diaminoheptanedioate
|
5.1.1.10
amino-acid racemase
5.1.1.7
diaminopimelate epimerase
|
–
–
|
|
BRENDA:
BR175
KEGG:
R02735
MetaCyc:
DIAMINOPIMEPIM-RXN
|
|
|
|
scyllo-inosose + L-glutamine <=> 1-amino-1-deoxy-scyllo-inositol + 2-Oxoglutaramate
|
2.6.1.50
glutamine---scyllo-inositol transaminase
|
–
|
|
BRENDA:
BR47697;
BS356684
KEGG:
R02781
MetaCyc:
2.6.1.50-RXN
|
|
|
|
7,9,12-Decaketide_intermediate_4 + NADPH + H+ <=> 7,9,12-Decaketide_intermediate_5 + NADP+
|
1.1.1
|
–
|
|
KEGG:
R09264
|
|
|
|
ATP + L-alanine + anticapsin <=> ADP + phosphate + L-alanyl-L-anticapsin + H+
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
BRENDA:
BR48759
KEGG:
R11064
MetaCyc:
RXN-16296
|
|
|
|
3-deacetyl-3-vinylbacteriochlorophyllide_a + ADP + phosphate + oxidized_ferredoxin <=> chlorophyllide_a + ATP + H2O + reduced_ferredoxin_[iron-sulfur]_cluster + H+
|
1.3.7.15
chlorophyllide a reductase
|
–
|
|
BRENDA:
BR50937
KEGG:
R09053
MetaCyc:
RXN-8792
|
|
|
|
15,9''-di-cis-phytofluene + plastoquinone <=> 9,15,9''-tri-cis-zeta-carotene + plastoquinol
|
1.3.5.5
15-cis-phytoene desaturase
|
–
|
|
BRENDA:
BR49668
KEGG:
R09654
MetaCyc:
RXN-12244
|
|
|
|
Rabelomycin <=> 11-Deoxylandomycinone
|
not assigned
|
–
|
|
KEGG:
R09346
|
|
|
|
UDP-glucose + 2''-deamino-2''-hydroxyneamine <=> Kanamycin_D + UDP + H+
|
2.4.1.301
2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase
|
–
|
|
KEGG:
R11271
MetaCyc:
RXN-13148
|
|
|
|
(22S)-22-hydroxycampesterol <=> (22S)-22-hydroxycampest-4-en-3-one
|
not assigned
|
–
|
|
KEGG:
R07446
|
|
|
|
dTDP-4-dehydro-6-deoxy-D-glucose <=> dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose
|
5.3.2.3
TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose-forming)
|
–
|
|
BRENDA:
BR49956
KEGG:
R09904
MetaCyc:
RXN-12839
|
|
|
|
dichloroarcyriaflavin_A + D-glucose <=> 4''-O-demethylrebeccamycin + H2O
|
4.3.3.5
4'-demethylrebeccamycin synthase
|
–
|
|
BRENDA:
BR49244
KEGG:
R09568
MetaCyc:
RXN-10846
|
|
|
|
amygdalin + H2O <=> prunasin + D-glucose
|
3.2.1.117
amygdalin beta-glucosidase
3.2.1.21
beta-glucosidase
|
–
–
|
|
BRENDA:
BR48182
KEGG:
R02985
MetaCyc:
AMYGDALIN-BETA-GLUCOSIDASE-RXN
SABIO-RK:
2837
|
|
|
|
9,14-Decaketide_intermediate_1 <=> tetracenomycin_F2 + [acyl-carrier_protein]
|
not assigned
|
–
|
|
KEGG:
R09355
|
|
|
|
Trachelanthamidine <=> retronecine
|
not assigned
|
–
|
|
KEGG:
R06725
|
|
|
|
3-devinyl-3-(1-hydroxyethyl)chlorophyllide_a + NAD+ <=> bacteriochlorophyllide_a + NADH + H+
|
1.1.1.396
bacteriochlorophyllide a dehydrogenase
|
–
|
|
BRENDA:
BR51634
KEGG:
R09055
MetaCyc:
RXN-8787
|
|
|
|
a_very-long-chain_(3R)-3-hydroxyacyl-CoA <=> very-long-chain_(2E)-2-enoyl-CoA + H2O
|
4.2.1.134
very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase
|
–
|
|
BRENDA:
BR50205
KEGG:
R10827
MetaCyc:
RXN-11750
|
|
|
|
Neoabietinol <=> Neoabietal
|
1.14.13
|
–
|
|
KEGG:
R06356
|
|
|
|
H+ + L-ornithine <=> CO2 + putrescine
|
4.1.1.17
ornithine decarboxylase
4.1.1.18
lysine decarboxylase
4.1.1.19
arginine decarboxylase
4.1.1.86
diaminobutyrate decarboxylase
4.1.1.B12
|
–
–
–
–
–
|
|
BRENDA:
BR277
KEGG:
R00670
MetaCyc:
ORNDECARBOX-RXN
SABIO-RK:
1050
|
|
|
|
alpha-D-glucose_6-phosphate <=> beta-D-glucose_6-phosphate
|
5.1.3.15
glucose-6-phosphate 1-epimerase
5.1.3.3
aldose 1-epimerase
5.3.1.9
glucose-6-phosphate isomerase
|
–
–
–
|
|
BRENDA:
BR190
KEGG:
R02739
MetaCyc:
GLUCOSE-6-PHOSPHATE-1-EPIMERASE-RXN
SABIO-RK:
13
|
|
|
|
gamma-carotene <=> beta-carotene
|
5.5.1.19
lycopene beta-cyclase
|
–
|
|
BRENDA:
BS427448
KEGG:
R03824
MetaCyc:
RXN1F-151
|
|
|
|
dTDP-4-hydroxyamino-4,6-dideoxy-alpha-D-glucose + Calicheamicinone <=> dTDP + Calicheamicin_T0
|
2.4.1
|
–
|
|
KEGG:
R11417
|
|
|
|
dTDP-6-deoxy-beta-L-talose <=> dTDP-L-rhamnose
|
5.1.3.25
dTDP-L-rhamnose 4-epimerase
|
–
|
|
BRENDA:
BR50340
KEGG:
R10279
MetaCyc:
RXN-13776
|
|
|
|
L-serine + acetyl-CoA <=> O-acetyl-L-serine + CoA
|
2.3.1.30
serine O-acetyltransferase
|
–
|
|
BRENDA:
BR44030
KEGG:
R00586
MetaCyc:
SERINE-O-ACETTRAN-RXN
SABIO-RK:
986
|
|
|
|
S-adenosyl-L-methionine + Orsellinate-[acp] <=> S-adenosyl-L-homocysteine + 2-Methoxyorsellinate-[acp]
|
2.1.1
|
–
|
|
KEGG:
R11413
|
|
|
|
(S)-2-Hydroxy-2-(4-hydroxyphenyl)acetate + O2 <=> 4-hydroxyphenylglyoxylate + H2O2
|
1.1.3.46
4-hydroxymandelate oxidase
|
–
|
|
BRENDA:
BR50849
KEGG:
R06633
MetaCyc:
RXN-15300
|
|
|
|
p-coumaryl_alcohol + NADP+ <=> 4-coumaraldehyde + NADPH + H+
|
1.1.1.195
cinnamyl-alcohol dehydrogenase
|
–
|
|
BRENDA:
BS230433;
BS426143
KEGG:
R07437
MetaCyc:
RXN-1102
SABIO-RK:
3739
|
|
|
|
NDP-2-amino-2,6-dideoxy-D-galactose <=> NDP-2-methylamino-2,6-dideoxy-D-galactose
|
2.1.1
|
–
|
|
KEGG:
R11434
|
|
|
|
Tropine + (R)-phenyllactyl-CoA <=> Littorine + CoA
|
2.3.1
2.3.1.185
tropine acyltransferase
|
–
–
|
|
KEGG:
R08432
MetaCyc:
RXN-8254
|
|
|
|
(1''S)-averantin + NADP+ <=> norsolorinic_acid + NADPH + H+
|
1.1.1.349
norsolorinic acid ketoreductase
1.1.1.B25
|
–
–
|
|
BRENDA:
BR50499
KEGG:
R10309
MetaCyc:
RXN-9480
|
|
|
|
TDP-3-dimethylamino-4,6-dideoxy-alpha-D-glucopyranose + L-oleandrosyl-oleandolide <=> oleandomycin + dTDP + H+
|
2.4.1
|
–
|
|
KEGG:
R06457
MetaCyc:
RXN-12803
|
|
|
|
UDP-glucose + beta-D-glucosyl_crocetin <=> H+ + beta-D-gentiobiosyl_crocetin + UDP
|
2.4.1.330
beta-D-glucosyl crocetin beta-1,6-glucosyltransferase
|
–
|
|
BRENDA:
BR51083
KEGG:
R10988
MetaCyc:
RXN-8472
|
|
|
|
deoxyamidinoproclavaminate + 2-oxoglutarate + O2 <=> amidinoproclavaminate + succinate + CO2
|
1.14.11.21
clavaminate synthase
|
–
|
|
BRENDA:
BR47603
KEGG:
R05466
MetaCyc:
1.14.11.21-RXN
|
|
|
|
aclacinomycin_S <=> aclacinomycin_N
|
not assigned
|
–
|
|
KEGG:
R09333
|
|
|
|
Chlorobiocic_acid + dTDP-beta-L-noviose <=> novclobiocin_105 + dTDP
|
not assigned
|
–
|
|
KEGG:
R06773
|
|
|
|
(S)-cis-N-Methylstylopine + reduced_flavodoxin + O2 <=> protopine + flavin + H2O
|
1.14.14.97
methyltetrahydroprotoberberine 14-monooxygenase
|
–
|
|
BRENDA:
BS186710
KEGG:
R04700
|
|
|
|
S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine <=> phosphatidylcholine + S-adenosyl-L-homocysteine + H+
|
2.1.1.16
methylene-fatty-acyl-phospholipid synthase
2.1.1.17
phosphatidylethanolamine N-methyltransferase
2.1.1.71
phosphatidyl-N-methylethanolamine N-methyltransferase
|
–
–
–
|
|
BRENDA:
BS319863
KEGG:
R01320
MetaCyc:
RXN4FS-2
SABIO-RK:
1534
|
|
|
|
H+ + 4-coumaroyl-CoA + malonyl-CoA + NADPH <=> isoliquiritigenin + CoA + CO2 + NADP+ + H2O
|
2.3.1.170
6'-deoxychalcone synthase
|
–
|
|
BRENDA:
BR48507
KEGG:
R06568
MetaCyc:
RXN-3142
|
|
|
|
5-diphosphomevalonate + ATP <=> isopentenyl_diphosphate + CO2 + ADP + phosphate
|
4.1.1.33
diphosphomevalonate decarboxylase
|
–
|
|
BRENDA:
BR292
KEGG:
R01121
MetaCyc:
DIPHOSPHOMEVALONTE-DECARBOXYLASE-RXN
SABIO-RK:
1380
|
|
|
|
Leucocyanidin + 2-oxoglutarate + O2 + H+ <=> cyanidin + succinate + CO2 + 2 H2O
|
1.14.20.4
anthocyanidin synthase
|
–
|
|
BRENDA:
BS397692
KEGG:
R05036
|
|
|
|
cannabigerolate + O2 <=> cannabidiolate + H2O2
|
1.21.3.3
reticuline oxidase
1.21.3.8
cannabidiolic acid synthase
|
–
–
|
|
BRENDA:
BR50270;
BS443261
KEGG:
R10160
MetaCyc:
RXN-7855
|
|
|
|
S-(Indolylmethylthiohydroximoyl)-L-cysteine + H2O <=> 2-(3-indolyl)acetothiohydroximate + pyruvate + NH3
|
4.4.1
|
–
|
|
KEGG:
R08170
|
|
|
|
peptidyl-4-carboxyglutamate + 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + H+ + H2O <=> CO2 + peptidyl-glutamate + vitamin_KH2 + O2
|
4.1.1.90
peptidyl-glutamate 4-carboxylase
|
–
|
|
BRENDA:
BR49124;
BS427500
KEGG:
R05144
MetaCyc:
RXN-10683
|
|
|
|
L-histidine <=> pilocarpine
|
not assigned
|
–
|
|
KEGG:
R08413
|
|
|
|
7-hydroxychlorophyllide_a <=> chlorophyllide_a
|
not assigned
|
–
|
|
KEGG:
R09066
|
|
|
|
H+ + Clavulanate-9-aldehyde + NADPH <=> clavulanic_acid + NADP+
|
not assigned
|
–
|
|
KEGG:
R05471
MetaCyc:
RXN-8893
|
|
|
|
FMN + O2 <=> 8-demethyl-8-formylriboflavin_5''-phosphate + H2O
|
2.6.1.114
8-demethyl-8-aminoriboflavin-5'-phosphate synthase
|
–
|
|
BRENDA:
BR52324
KEGG:
R11961
MetaCyc:
RXN-18509
|
|
|
|
L-homoserine + succinyl-CoA <=> O-succinyl-L-homoserine + CoA
|
2.3.1.46
homoserine O-succinyltransferase
|
–
|
|
BRENDA:
BR44047
KEGG:
R01777
MetaCyc:
HOMSUCTRAN-RXN
|
|
|
|
a_3-vinyl_bacteriochlorophyllide_d + (2E,6E)-farnesyl_diphosphate <=> Bacteriochlorophyll_d + diphosphate
|
2.5.1
|
–
|
|
KEGG:
R09065
|
|
|
|
24-ethylidenelophenol + ferricytochrome_b5 + O2 + H+ <=> 4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol + ferricytochrome_b5 + H2O
|
1.14.18.11
plant 4alpha-monomethylsterol monooxygenase
|
–
|
|
BRENDA:
BS446036
KEGG:
R12379
MetaCyc:
RXN-19723
|
|
|
|
tetracenomycin_B2 + O2 + NADPH + H+ <=> 8-demethyltetracenomycin_C + H2O + NADP+
|
1.14.13.200
tetracenomycin A2 monooxygenase-dioxygenase
|
–
|
|
BRENDA:
BS429406
KEGG:
R10954
MetaCyc:
RXN-15407
|
|
|
|
GTP + valienol_1-phosphate + H+ <=> GDP-valienol + diphosphate
|
2.7.7.91
valienol-1-phosphate guanylyltransferase
|
–
|
|
BRENDA:
BR51761
KEGG:
R11402
MetaCyc:
RXN-17377
|
|
|
|
lanosterol + O2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + oxidized_ferredoxin + H2O
|
1.14.15.36
sterol 14alpha-demethylase (ferredoxin)
|
–
|
|
KEGG:
R12323
MetaCyc:
RXN-20130
|
|
|
|
2-phospho-D-glycerate <=> 3-phospho-D-glycerate
|
5.4.2.11
phosphoglycerate mutase (2,3-diphosphoglycerate-dependent)
5.4.2.12
phosphoglycerate mutase (2,3-diphosphoglycerate-independent)
|
–
–
|
|
BRENDA:
BR17
KEGG:
R01518
MetaCyc:
3PGAREARR-RXN;
RXN-15513
SABIO-RK:
7641
|
|
|
|
thebaine + 2-oxoglutarate + O2 <=> oripavine + formaldehyde + succinate + CO2
|
1.14.11.32
codeine 3-O-demethylase
|
–
|
|
BRENDA:
BS406754
KEGG:
R05127
MetaCyc:
RXN-8149
|
|
|
|
Leucocyanidin + NADP+ <=> taxifolin + NADPH + H+
|
1.1.1.219
dihydroflavonol 4-reductase
|
–
|
|
BRENDA:
BS230654;
BS371573
KEGG:
R03636
MetaCyc:
RXN-600
|
|
|
|
3-dehydroshikimate <=> 3,4-dihydroxybenzoate + H2O
|
4.2.1.118
3-dehydroshikimate dehydratase
|
–
|
|
BRENDA:
BR49127
KEGG:
R01627
MetaCyc:
DHSHIKIMATE-DEHYDRO-RXN
SABIO-RK:
1768
|
|
|
|
(9S,10E,12Z,15Z)-9-hydroperoxy-10,12,15-octadecatrienoate <=> 9-Oxononanoate + 3,6-Nonadienal
|
not assigned
|
–
|
|
KEGG:
R07868
|
|
|
|
UDP-glucose + bis(beta-D-glucosyl)_crocetin <=> H+ + beta-D-gentiobiosyl_beta-D-glucosyl_crocetin + UDP
|
2.4.1.330
beta-D-glucosyl crocetin beta-1,6-glucosyltransferase
|
–
|
|
BRENDA:
BR51084
KEGG:
R10989
MetaCyc:
RXN-8474
|
|
|
|
4''-O-Desmethylpapaveroxine <=> narcotoline_hemiacetal
|
not assigned
|
–
|
|
KEGG:
R11695
|
|
|
|
(-)-vetispiradiene + reduced_flavodoxin + O2 <=> solavetivol + flavin + H2O
|
1.14.14.151
premnaspirodiene oxygenase
|
–
|
|
BRENDA:
BR49420
KEGG:
R09576
|
|
|
|
S-adenosyl-L-methionine + Glandicoline_B <=> Meleagrin + S-adenosyl-L-homocysteine + H+
|
2.1.1
|
–
|
|
KEGG:
R12443
MetaCyc:
RXN-16145
|
|
|
|
ent-7alpha-hydroxykaur-16-en-19-oate + reduced_flavodoxin + O2 <=> 6beta,7beta-Dihydroxykaurenoic_acid + flavin + H2O
|
1.14.14.107
ent-kaurenoic acid monooxygenase
|
–
|
|
KEGG:
R06296
|
|
|
|
glycolate + O2 <=> glyoxylate + H2O2
|
1.1.3.13
alcohol oxidase
1.1.3.15
(S)-2-hydroxy-acid oxidase
|
–
–
|
|
BRENDA:
BS257485
KEGG:
R00475
MetaCyc:
RXN-969
SABIO-RK:
907
|
|
|
|
dTDP-3-O-methyl-4-oxo-2,6-dideoxy-L-mannose <=> dTDP-L-oleandrose
|
not assigned
|
–
|
|
KEGG:
R11042
|
|
|
|
L-alpha-glycerophosphate + NADP+ <=> dihydroxyacetone_phosphate + NADPH + H+
|
1.1.1.156
glycerol 2-dehydrogenase (NADP+)
1.1.1.191
indole-3-acetaldehyde reductase (NADPH)
1.1.1.2
alcohol dehydrogenase (NADP+)
1.1.1.21
aldose reductase
1.1.1.261
sn-glycerol-1-phosphate dehydrogenase
1.1.1.49
glucose-6-phosphate dehydrogenase (NADP+)
1.1.1.8
glycerol-3-phosphate dehydrogenase (NAD+)
1.1.1.94
glycerol-3-phosphate dehydrogenase [NAD(P)+]
1.3.1.20
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
|
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BR22612;
BR29350
KEGG:
R00844;
R05680
MetaCyc:
1.1.1.261-RXN;
GLYC3PDEHYDROGBIOSYN-RXN
SABIO-RK:
1184;
5276
|
|
|
|
(6E)-8-hydroxygeraniol + NADP+ <=> (6E)-8-oxogeranial + NADPH + H+
|
1.1.1.324
8-hydroxygeraniol dehydrogenase
|
–
|
|
BRENDA:
BR50014
KEGG:
R08499
MetaCyc:
RXN-12961
|
|
|
|
squalene + H2O <=> hopan-22-ol
|
4.2.1.129
squalene---hopanol cyclase
5.4.99.17
squalene---hopene cyclase
|
–
–
|
|
BRENDA:
BR40505
KEGG:
R07323
MetaCyc:
RXN-4961
SABIO-RK:
6686
|
|
|
|
Stemmadenine <=> Catharanthine
|
not assigned
|
–
|
|
KEGG:
R05854
|
|
|
|
tryptamine <=> eserine
|
not assigned
|
–
|
|
KEGG:
R08481
|
|
|
|
gardneral + acetyl-CoA <=> vinorine + CoA
|
2.3.1.160
vinorine synthase
|
–
|
|
BRENDA:
BR44010
KEGG:
R05876
MetaCyc:
2.3.1.160-RXN
|
|
|
|
O2 + (S)-reticuline <=> H+ + H2O2 + (S)-scoulerine
|
1.21.3.3
reticuline oxidase
|
–
|
|
BRENDA:
BR36965
KEGG:
R03831
MetaCyc:
RETICULINE-OXIDASE-RXN
|
|
|
|
4-hydroxy-6-methylpretetramide + NADPH + O2 + H+ <=> 4-de(dimethylamino)-4-oxoanhydrotetracycline + NADP+ + H2O
|
1.14.13.233
4-hydroxy-6-methylpretetramide 12a-monooxygenase
|
–
|
|
BRENDA:
BR51808
KEGG:
R05462
MetaCyc:
RXN-17980
|
|
|
|
alpha-D-glucose + ADP <=> alpha-D-glucose_6-phosphate + AMP
|
2.7.1.147
ADP-specific glucose/glucosamine kinase
|
–
|
|
KEGG:
R09085
|
|
|
|
L-proline + a_quinone <=> L-pyrroline-5-carboxylate + a_quinol
|
1.5.5.2
proline dehydrogenase
1.5.99.B2
|
–
–
|
|
BRENDA:
BR36918
KEGG:
R01253
|
|
|
|
S-adenosyl-L-methionine + magnesium_protoporphyrin_monomethyl_ester + H2O <=> 131-hydroxy-magnesium-protoporphyrin_IX_13-monomethyl_ester + 5''-deoxyadenosine + L-methionine + H+
|
1.21.98.3
anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase
|
–
|
|
BRENDA:
BR51845
KEGG:
R06268
MetaCyc:
RXN-8797
|
|
|
|
(2E,6E)-farnesyl_diphosphate + isopentenyl_diphosphate <=> all-trans-heptaprenyl_diphosphate + diphosphate
|
2.5.1.30
heptaprenyl diphosphate synthase
2.5.1.B41
|
–
–
|
|
BRENDA:
BR47476
KEGG:
R09247
MetaCyc:
TRANS-HEXAPRENYLTRANSTRANSFERASE-RXN
SABIO-RK:
13830
|
|
|
|
germacrene_A + O2 + reduced_flavodoxin <=> germacra-1(10),4,11(13)-trien-12-ol + flavin + H2O
|
1.14.14.95
germacrene A hydroxylase
|
–
|
|
BRENDA:
BR52444
KEGG:
R09549
|
|
|
|
glycine + tetrahydrofolate + NAD+ <=> 5,10-methylenetetrahydrofolate + NH3 + CO2 + NADH
|
1.4.1.f
1.4.4.2
glycine dehydrogenase (aminomethyl-transferring)
1.8.1.4
dihydrolipoyl dehydrogenase
2.1.2.10
aminomethyltransferase
|
–
–
–
–
|
|
KEGG:
R01221
MetaCyc:
GCVMULTI-RXN
SABIO-RK:
1451
|
|
|
|
(2S,5S)-5-carboxymethylproline + ATP <=> H+ + (3S,5S)-carbapenam_3-carboxylate + AMP + diphosphate
|
6.3.3.6
carbapenam-3-carboxylate synthase
|
–
|
|
BRENDA:
BR50731
KEGG:
R10556
MetaCyc:
RXN-8948
|
|
|
|
coniferyl_alcohol + NADP+ <=> coniferyl_aldehyde + NADPH + H+
|
1.1.1.194
coniferyl-alcohol dehydrogenase
1.1.1.195
cinnamyl-alcohol dehydrogenase
1.1.1.2
alcohol dehydrogenase (NADP+)
1.1.1.90
aryl-alcohol dehydrogenase
1.1.1.91
aryl-alcohol dehydrogenase (NADP+)
|
–
–
–
–
–
|
|
BRENDA:
BR36707
KEGG:
R02593
MetaCyc:
RXN-2602
SABIO-RK:
2499
|
|
|
|
validamycin_A + 2-oxoglutarate + O2 <=> validamycin_B + succinate + CO2
|
1.14.11.52
validamycin A dioxygenase
|
–
|
|
BRENDA:
BR51692
KEGG:
R11340
MetaCyc:
RXN-17381
|
|
|
|
cathenamine + NADPH + H+ <=> Tetrahydroalstonine + NADP+
|
not assigned
|
–
|
|
KEGG:
R05848
|
|
|
|
protodeoxyviolaceinate + O2 + NADPH + H+ <=> protoviolaceinate + NADP+ + H2O
|
1.14.13.217
protodeoxyviolaceinate monooxygenase
1.14.13.224
violacein synthase
|
–
–
|
|
BRENDA:
BR51577
KEGG:
R11132;
R11134
MetaCyc:
RXN-13341;
RXN-13344
|
|
|
|
resveratrol <=> piceatannol
|
1.14
|
–
|
|
KEGG:
R04257
|
|
|
|
L-valine + reduced_flavodoxin + O2 <=> N-hydroxy-L-valine + flavin + H2O
|
1.14.14.38
valine N-monooxygenase
1.14.14.39
isoleucine N-monooxygenase
|
–
–
|
|
BRENDA:
BR49381
KEGG:
R10031
|
|
|
|
H+ + versicolorone + NADPH + O2 <=> versiconol_acetate + NADP+ + H2O
|
not assigned
|
–
|
|
KEGG:
R10478
MetaCyc:
RXN-9492
|
|
|
|
Avermectin_A1b_aglycone + dTDP-L-oleandrose <=> Avermectin_A1b_monosaccharide + dTDP
|
2.4.1
|
–
|
|
KEGG:
R06498
|
|
|
|
Gibberellin_A24 + 2-oxoglutarate + O2 <=> Gibberellin_A36 + succinate + CO2
|
1.14.11
|
–
|
|
KEGG:
R06335
MetaCyc:
RXN-6523
|
|
|
|
nicotinate + 3,6-Dihydropyridine <=> Anatabine + CO2
|
not assigned
|
–
|
|
KEGG:
R06779
|
|
|
|
5''''''-epi-Lividomycin_B <=> Lividomycin_B
|
5.1.3
|
–
|
|
KEGG:
R11288
|
|
|
|
S-adenosyl-L-methionine + 8-demethyl-8-(2,3-O-dimethyl-alpha-L-rhamnosyl)-tetracenomycin_C <=> 8-demethyl-8-(2,3,4-O-trimethyl-alpha-L-rhamnosyl)-tetracenomycin_C + S-adenosyl-L-homocysteine + H+
|
2.1.1.307
8-demethyl-8-(2,3-dimethoxy-alpha-L-rhamnosyl)tetracenomycin-C 4'-O-methyltransferase
|
–
|
|
BRENDA:
BR50859
KEGG:
R10958
MetaCyc:
RXN-15403
|
|
|
|
5-Oxoavermectin_''''1b''''_aglycone + NADPH + H+ <=> Avermectin_B1b_aglycone + NADP+
|
not assigned
|
–
|
|
KEGG:
R06475
|
|
|
|
dTDP-glucose + 2 NAD+ + H2O <=> dTDP-D-glucuronate + 2 NADH + 2 H+
|
1.1.1
|
–
|
|
KEGG:
R11471
|
|
|
|
(9S,10E,12Z,15Z)-9-hydroperoxy-10,12,15-octadecatrienoate <=> 9,10-EOT + H2O
|
4.2.1.92
hydroperoxide dehydratase
|
–
|
|
KEGG:
R07865
MetaCyc:
RXN-8500
|
|
|
|
dimethylallyl_diphosphate + adenine_in_tRNA <=> diphosphate + tRNA_containing_6-isopentenyladenosine
|
2.5.1.75
tRNA dimethylallyltransferase
|
–
|
|
KEGG:
R01122
|
|
|
|
(2E,6E)-farnesyl_diphosphate <=> (E)-alpha-bisabolene + diphosphate
|
4.2.3.38
alpha-bisabolene synthase
|
–
|
|
BRENDA:
BR49017
KEGG:
R08370
MetaCyc:
RXN-8550
|
|
|
|
obtusifoliol + reduced_flavodoxin + O2 <=> 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + formate + flavin + H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
BRENDA:
BS186733
KEGG:
R05731
|
|
|
|
2-hydroxyethylphosphonate + NAD+ <=> phosphonoacetaldehyde + NADH + H+
|
1.1.1.309
phosphonoacetaldehyde reductase (NADH)
|
–
|
|
BRENDA:
BR49249
KEGG:
R09478
MetaCyc:
RXN-9009
|
|
|
|
L-2-aminoadipate + L-cysteine + L-valine + ATP + H2O <=> H+ + N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + AMP + diphosphate
|
6.3.2.26
N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase
|
–
|
|
BRENDA:
BR40508
KEGG:
R04870
MetaCyc:
6.3.2.26-RXN
|
|
|
|
2''-deamino-2''-hydroxyparomamine + O2 <=> 2''-deamino-2''-hydroxy-6''-dehydroparomamine + H2O2
|
1.1.3
|
–
|
|
KEGG:
R10207
MetaCyc:
RXN-13166
|
|
|
|
6''''''-hydroxyparomomycin + O2 <=> 6''''''-oxoparomomycin + H2O2
|
1.1.3
|
–
|
|
KEGG:
R11284
MetaCyc:
RXN-13211
|
|
|
|
dTDP-L-olivose + NADP+ <=> dTDP-4-oxo-2,6-dideoxy-L-mannose + NADPH + H+
|
1.1.1
|
–
|
|
KEGG:
R06434
MetaCyc:
RXN-12929
|
|
|
|
(3Z)-hex-3-en-ol + NAD+ <=> cis-3-hexenal + NADH + H+
|
1.1.1.1
alcohol dehydrogenase
|
–
|
|
KEGG:
R10783
MetaCyc:
RXN-1347
|
|
|
|
(S)-scoulerine + reduced_flavodoxin + O2 <=> (S)-cheilanthifoline + flavin + 2 H2O
|
1.14.19.65
(S)-cheilanthifoline synthase
|
–
|
|
BRENDA:
BR37081
KEGG:
R03834
|
|
|
|
Lolitriol + dimethylallyl_diphosphate <=> Lolitrem_E + diphosphate
|
2.5.1
|
–
|
|
KEGG:
R10370
MetaCyc:
RXN-15964
|
|
|
|
N-(5-phospho-beta-D-ribosyl)anthranilate + diphosphate <=> anthranilate + 5-phospho-alpha-D-ribose_1-diphosphate
|
2.4.2.18
anthranilate phosphoribosyltransferase
|
–
|
|
BRENDA:
BR47560
KEGG:
R01073
MetaCyc:
PRTRANS-RXN
SABIO-RK:
1341
|
|
|
|
Emindole_SB + O2 + NADPH + H+ <=> 14,15-Epoxyemindole_SB + NADP+ + H2O
|
1.14.13
|
–
|
|
KEGG:
R10351
MetaCyc:
RXN-15496
|
|
|
|
(-)-trans-isopiperitenol + NAD+ <=> (-)-isopiperitenone + NADH + H+
|
1.1.1.223
isopiperitenol dehydrogenase
|
–
|
|
BRENDA:
BR29264
KEGG:
R03261
MetaCyc:
ISOPIPERITENOL-DEHYDROGENASE-RXN
|
|
|
|
beta-tocopherol <=> alpha-tocopherol
|
not assigned
|
–
|
|
KEGG:
R07508
|
|
|
|
chlortetracycline + NADPH + H+ + O2 <=> 11a-Hydroxy-7-chlortetracycline + NADP+ + H2O
|
1.14.13.231
tetracycline 11a-monooxygenase
|
–
|
|
KEGG:
R11526
|
|
|
|
tabersonine <=> Lochnerinine
|
not assigned
|
–
|
|
KEGG:
R05886
|
|
|
|
pentalenene + O2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> pentalen-13-al + H2O + oxidized_ferredoxin
|
1.14.15.32
pentalenene oxygenase
|
–
|
|
BRENDA:
BR49819
KEGG:
R09814
MetaCyc:
RXN-13400
|
|
|
|
dTDP-acarviose-7-phosphate <=> acarbose_7'''-phosphate
|
not assigned
|
–
|
|
KEGG:
R11248
|
|
|
|
1-(2-aminophenyl)decane-1,3-dione <=> 2-heptyl-4(1H)-quinolone + H2O
|
2.3.1.230
2-heptyl-4(1H)-quinolone synthase
|
–
|
|
BRENDA:
BR51959
KEGG:
R11590
MetaCyc:
RXN-17705
|
|
|
|
a_very-long-chain_(3R)-3-hydroxyacyl-CoA + NADP+ <=> a_very-long-chain_3-oxoacyl-CoA + NADPH + H+
|
1.1.1.330
very-long-chain 3-oxoacyl-CoA reductase
|
–
|
|
BRENDA:
BR50139
KEGG:
R10826
|
|
|
|
4-Chloro-L-lysine + reduced_acceptor + O2 <=> 2-Amino-4-chloro-4-pentenoic_acid + acceptor + formaldehyde + NH3 + H2O
|
1.14.99
|
–
|
|
KEGG:
R12408
|
|
|
|
N-Acetyl-N6,O-didemethylpuromycin-5''-phosphate + S-adenosyl-L-methionine <=> N-Acetyl-O-demethylpuromycin-5''-phosphate + S-adenosyl-L-homocysteine
|
2
|
–
|
|
KEGG:
R05674
|
|
|
|
paraxanthine <=> 5-Acetylamino-6-formylamino-3-methyluracil
|
2.3.1.5
arylamine N-acetyltransferase
|
–
|
|
KEGG:
R07940
|
|
|
|
gibberellin_a9 + 2-oxoglutarate + O2 <=> gibberellin_A51 + succinate + CO2
|
1.14.11
1.14.11.13
gibberellin 2beta-dioxygenase
|
–
–
|
|
KEGG:
R06337
MetaCyc:
RXN-171
|
|
|
|
4''-Oxonebramine + NADPH + H+ <=> nebramine + NADP+
|
1.1.1
|
–
|
|
KEGG:
R11277
|
|
|
|
2-methylacetoacetyl-CoA + CoA <=> propionyl-CoA + acetyl-CoA
|
2.3.1.16
acetyl-CoA C-acyltransferase
2.3.1.9
acetyl-CoA C-acetyltransferase
|
–
–
|
|
BRENDA:
BS407013
KEGG:
R00927
MetaCyc:
METHYLACETOACETYLCOATHIOL-RXN
|
|
|
|
NADP+ + (-)-menthol <=> H+ + (-)-menthone + NADPH
|
1.1.1.207
(-)-menthol dehydrogenase
|
–
|
|
BRENDA:
BR33668
KEGG:
R02177
MetaCyc:
--MENTHOL-DEHYDROGENASE-RXN
SABIO-RK:
2150
|
|
|
|
H+ + glycine + succinyl-CoA <=> CO2 + CoA + 5-aminolevulinate
|
2.3.1.37
5-aminolevulinate synthase
|
–
|
|
BRENDA:
BR44037
KEGG:
R00830
MetaCyc:
5-AMINOLEVULINIC-ACID-SYNTHASE-RXN
|
|
|
|
1-carboxyvinyl_carboxyphosphonate + H+ <=> CO2 + (hydroxyphosphinyl)pyruvate
|
2.7.8.23
carboxyvinyl-carboxyphosphonate phosphorylmutase
|
–
|
|
BRENDA:
BR47910
KEGG:
R05165
MetaCyc:
2.7.8.23-RXN
|
|
|
|
(1R,2S,5S,6S)-2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate <=> (1R,6R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate + pyruvate
|
4.2.99.20
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase
|
–
|
|
BRENDA:
BR48915
KEGG:
R08166
MetaCyc:
RXN-9310
|
|
|
|
tRNAMet + L-glutamate + ATP <=> Glu-tRNAGln + diphosphate + AMP
|
6.1.1.17
glutamate---tRNA ligase
6.1.1.24
glutamate---tRNAGln ligase
|
–
–
|
|
KEGG:
R05578
|
|
|
|
gamma-tocotrienol <=> 6-geranylgeranyl-2,3-dimethylbenzene-1,4-diol
|
5.5.1.24
tocopherol cyclase
|
–
|
|
BRENDA:
BR50794;
BS427883
KEGG:
R10624
MetaCyc:
RXN-14922
|
|
|
|
S-adenosyl-L-methionine + caffeic_acid <=> H+ + ferulic_acid + S-adenosyl-L-homocysteine
|
2.1.1.104
caffeoyl-CoA O-methyltransferase
2.1.1.68
caffeate O-methyltransferase
|
–
–
|
|
BRENDA:
BR43911
KEGG:
R03366
MetaCyc:
RXN-1104
SABIO-RK:
14976
|
|
|
|
5-hydroxyconiferaldehyde + NADPH <=> 5-hydroxyconiferyl_alcohol + NADP+
|
1.1.1.195
cinnamyl-alcohol dehydrogenase
|
–
|
|
BRENDA:
BS383957
KEGG:
R06570
SABIO-RK:
6145
|
|
|
|
H2O + isochorismate <=> pyruvate + (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate
|
3.3.2.1
isochorismatase
|
–
|
|
BRENDA:
BR32614
KEGG:
R03037
MetaCyc:
ISOCHORMAT-RXN
|
|
|
|
S-adenosyl-L-methionine + Pretetramid <=> S-adenosyl-L-homocysteine + 6-methylpretetramide + H+
|
2.1.1
2.1.1.M31
|
–
–
|
|
KEGG:
R09189
MetaCyc:
RXN-17982
|
|
|
|
dodecanoyl-[acyl-carrier_protein] + H2O <=> [acyl-carrier_protein] + laurate + H+
|
3.1.2.14
oleoyl-[acyl-carrier-protein] hydrolase
3.1.2.21
dodecanoyl-[acyl-carrier-protein] hydrolase
|
–
–
|
|
BRENDA:
BR2506;
BS12699
KEGG:
R04014
MetaCyc:
3.1.2.21-RXN
SABIO-RK:
3749
|
|
|
|
ATP + formylglycinamide_ribonucleotide + L-glutamine + H2O <=> H+ + L-glutamate + ADP + phosphate + 2-(formamido)-N1-(5-phosphoribosyl)acetamidine
|
6.3.5.3
phosphoribosylformylglycinamidine synthase
|
–
|
|
BRENDA:
BR150
KEGG:
R04463
MetaCyc:
FGAMSYN-RXN
|
|
|
|
(2E,6E)-farnesyl_diphosphate + isopentenyl_diphosphate <=> di-trans-poly-cis-decaprenyl_diphosphate + diphosphate
|
2.5.1.87
ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific]
2.5.1.91
all-trans-decaprenyl-diphosphate synthase
|
–
–
|
|
BRENDA:
BR49323
KEGG:
R09249
MetaCyc:
RXN-21509;
RXN-9106
|
|
|
|
L-serine + indole <=> L-tryptophan + H2O
|
4.1.99.1
tryptophanase
4.2.1.122
tryptophan synthase (indole-salvaging)
4.2.1.20
tryptophan synthase
|
–
–
–
|
|
BRENDA:
BR49621
KEGG:
R00674
MetaCyc:
RXN0-2382
SABIO-RK:
1054
|
|
|
|
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> 2-hydroxy-5-methyl-1-naphthoate + CoA + CO2 + H2O + NADP+
|
2.3.1.237
neocarzinostatin naphthoate synthase
|
–
|
|
BRENDA:
BR51201
KEGG:
R11125
MetaCyc:
RXN-15689
|
|
|
|
S-adenosyl-L-methionine + 2-methoxy-6-polyprenyl-1,4-benzoquinol <=> 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + S-adenosyl-L-homocysteine + H+
|
2.1.1.201
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase
|
–
|
|
BRENDA:
BR49307;
BS410184
KEGG:
R09737
MetaCyc:
RXN-11754
|
|
|
|
3''-phosphoadenylyl-sulfate + desulfoglucotropaeolin <=> adenosine_3,5''-bisphosphate + benzylglucosinolate + H+
|
2.8.2.24
aromatic desulfoglucosinolate sulfotransferase
2.8.2.38
aliphatic desulfoglucosinolate sulfotransferase
|
–
–
|
|
BRENDA:
BR47919;
BS358758
KEGG:
R03214
MetaCyc:
RXN-4606
|
|
|
|
5-amino-2,6-dioxy-4-(5'-phosphoribitylamino)pyrimidine + H2O <=> 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione + phosphate
|
3.1.3.104
5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase
|
–
|
|
BRENDA:
BR51773
KEGG:
R07280
MetaCyc:
RIBOPHOSPHAT-RXN
SABIO-RK:
8920
|
|
|
|
an_alcohol + NAD+ <=> an_aldehyde + NADH + H+
|
1.1.1.1
alcohol dehydrogenase
1.1.1.103
L-threonine 3-dehydrogenase
1.1.1.11
D-arabinitol 4-dehydrogenase
1.1.1.14
L-iditol 2-dehydrogenase
1.1.1.17
mannitol-1-phosphate 5-dehydrogenase
1.1.1.184
carbonyl reductase (NADPH)
1.1.1.192
long-chain-alcohol dehydrogenase
1.1.1.2
alcohol dehydrogenase (NADP+)
1.1.1.202
1,3-propanediol dehydrogenase
1.1.1.21
aldose reductase
1.1.1.244
methanol dehydrogenase
1.1.1.245
cyclohexanol dehydrogenase
1.1.1.284
S-(hydroxymethyl)glutathione dehydrogenase
1.1.1.306
S-(hydroxymethyl)mycothiol dehydrogenase
1.1.1.307
D-xylose reductase
1.1.1.6
glycerol dehydrogenase
1.1.1.71
alcohol dehydrogenase [NAD(P)+]
1.1.1.73
octanol dehydrogenase
1.1.1.77
lactaldehyde reductase
1.1.1.78
methylglyoxal reductase (NADH)
1.1.1.80
isopropanol dehydrogenase (NADP+)
1.1.1.B4
|
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BR29164;
BS139564;
BS405084
KEGG:
R00623;
R00754;
R07326
MetaCyc:
ALCOHOL-DEHYDROG-GENERIC-RXN;
ALCOHOL-DEHYDROG-RXN;
ALCOHOL-DEHYDROGENASE-NADP+-RXN_WOP
SABIO-RK:
597
|
|
|
|
novclobiocin_104 + (1H-pyrrole-2-carbonyl)-[peptidyl-carrier_protein] <=> Clorobiocin
|
not assigned
|
–
|
|
KEGG:
R06775
|
|
|
|
(1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate + O2 <=> (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylate + H2O2
|
1.10.3.16
dihydrophenazinedicarboxylate synthase
|
–
|
|
BRENDA:
BR51793;
BS436586
KEGG:
R11489
MetaCyc:
RXN-12021
|
|
|
|
festuclavine + NAD+ <=> 6,8-dimethyl-6,7-didehydroergoline + NADH + H+
|
1.5.1.44
festuclavine dehydrogenase
|
–
|
|
BRENDA:
BR50245
KEGG:
R10163
MetaCyc:
RXN-13478
|
|
|
|
stemod-13(17)-ene + 3 O2 + 3 reduced_flavodoxin <=> syn-stemoden-19-oate + 3 flavin + 4 H2O
|
1.14.14.111
9beta-pimara-7,15-diene oxidase
|
–
|
|
KEGG:
R09921
|
|
|
|
3-geranyl-4-hydroxybenzoate + H+ <=> 2-polyprenylphenol + CO2
|
4.1.1.98
4-hydroxy-3-polyprenylbenzoate decarboxylase
|
–
|
|
BRENDA:
BR51054
KEGG:
R04985
MetaCyc:
RXN-15309
|
|
|
|
S-adenosyl-L-methionine + (S)-tetrahydrocolumbamine <=> H+ + S-adenosyl-L-homocysteine + (-)-tetrahydropalmatine
|
2.1.1.117
(S)-scoulerine 9-O-methyltransferase
2.1.1.89
tetrahydrocolumbamine 2-O-methyltransferase
|
–
–
|
|
BRENDA:
BR43929;
BS456368
KEGG:
R04077
MetaCyc:
2.1.1.89-RXN
SABIO-RK:
3808
|
|
|
|
N6-(2-isopentenyl)adenine + reduced_flavodoxin + O2 <=> trans-zeatin + flavin + H2O
|
not assigned
|
–
|
|
KEGG:
R08068
|
|
|
|
NADP+ + bilirubin <=> Biliverdin + NADPH + H+
|
1.3.1.24
biliverdin reductase
|
–
|
|
BRENDA:
BR40361
KEGG:
R02393
MetaCyc:
BILIVERDIN-REDUCTASE-RXN
SABIO-RK:
2334
|
|
|
|
2-aminobenzoyl-CoA + malonyl-CoA + H+ <=> 4-hydroxy-2-methylquinoline + CoA + CO2
|
2.3.1
|
–
|
|
KEGG:
R12049
MetaCyc:
RXN-15021
|
|
|
|
ent-kaur-16-en-19-al + reduced_flavodoxin + O2 <=> ent-kaur-16-en-19-oate + flavin + H2O
|
1.14.14.86
ent-kaurene monooxygenase
|
–
|
|
BRENDA:
BR40527
KEGG:
R06293
|
|
|
|
copalyl_diphosphate + H2O <=> phyllocladan-16alpha-ol + diphosphate
|
4.2.3.45
phyllocladan-16alpha-ol synthase
|
–
|
|
BRENDA:
BR49129
KEGG:
R09686
MetaCyc:
RXN-10775
|
|
|
|
acetyl-CoA + dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose <=> CoA + dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose + H+
|
2.3.1.197
dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase
|
–
|
|
BRENDA:
BR49889
KEGG:
R09873
MetaCyc:
RXN-12806
|
|
|
|
L-tyrosine + O2 <=> L-Dopa
|
1.10.3.1
catechol oxidase
1.14.18.1
tyrosinase
|
–
–
|
|
BRENDA:
BR50166
KEGG:
R00031;
R00731
MetaCyc:
RXN-5861
SABIO-RK:
1094;
622
|
|
|
|
alpha-D-glucose_1-phosphate + UTP + H+ <=> UDP-glucose + diphosphate
|
2.7.7.23
UDP-N-acetylglucosamine diphosphorylase
2.7.7.24
glucose-1-phosphate thymidylyltransferase
2.7.7.28
nucleoside-triphosphate-aldose-1-phosphate nucleotidyltransferase
2.7.7.33
glucose-1-phosphate cytidylyltransferase
2.7.7.64
UTP-monosaccharide-1-phosphate uridylyltransferase
2.7.7.9
UTP---glucose-1-phosphate uridylyltransferase
|
–
–
–
–
–
–
|
|
BRENDA:
BR47905;
BR48768;
BS383404
KEGG:
R00289;
R08845
MetaCyc:
GLUC1PURIDYLTRANS-RXN
SABIO-RK:
68;
8973
|
|
|
|
phosphoribulosylformimino-AICAR-phosphate + L-glutamine <=> H+ + L-glutamate + D-erythro-1-(imidazol-4-yl)glycerol_3-phosphate + 5-aminoimidazole-4-carboxamide_ribonucleotide
|
2.4.2
4.3.1.B2
4.3.2.10
imidazole glycerol-phosphate synthase
|
–
–
–
|
|
BRENDA:
BR51141;
BR52465
KEGG:
R04558
MetaCyc:
GLUTAMIDOTRANS-RXN
SABIO-RK:
4234
|
|
|
|
citral + NAD+ + H2O <=> trans-geranic_acid + NADH + H+
|
1.2.1.3
aldehyde dehydrogenase (NAD+)
1.2.1.36
retinal dehydrogenase
1.2.1.86
geranial dehydrogenase
1.2.1.94
farnesal dehydrogenase
|
–
–
–
–
|
|
BRENDA:
BR50237
KEGG:
R08086
MetaCyc:
RXN-11970
SABIO-RK:
9881;
9889
|
|
|
|
3-[(2S,5R)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-yl]-2-oxopropanoate + L-phenylalanine <=> L-dihydroanticapsin + phenylpyruvate
|
2.6.1
|
–
|
|
KEGG:
R11068
MetaCyc:
RXN-16297
|
|
|
|
tetracenomycin_A2 + O2 + NADPH + H+ <=> tetracenomycin_C + H2O + NADP+
|
1.14.13.200
tetracenomycin A2 monooxygenase-dioxygenase
|
–
|
|
BRENDA:
BR51077
KEGG:
R06704
MetaCyc:
RXN-15434
|
|
|
|
S-adenosyl-L-methionine + demethyldecarbamoylnovobiocin <=> S-adenosyl-L-homocysteine + decarbamoylnovobiocin + H+
|
2.1.1.285
demethyldecarbamoylnovobiocin O-methyltransferase
|
–
|
|
BRENDA:
BR50631
KEGG:
R06771
MetaCyc:
RXN-14545
|
|
|
|
kanamycin_B + 2-oxoglutarate + O2 <=> 2''-dehydrokanamycin_A + succinate + NH3 + CO2
|
1.14.11.37
kanamycin B dioxygenase
|
–
|
|
BRENDA:
BR50514
KEGG:
R10312
MetaCyc:
RXN-14401
|
|
|
|
O-phospho-L-serine + H2O <=> L-serine + phosphate
|
3.1.3.1
alkaline phosphatase
3.1.3.15
histidinol-phosphatase
3.1.3.16
protein-serine/threonine phosphatase
3.1.3.2
acid phosphatase
3.1.3.20
phosphoglycerate phosphatase
3.1.3.26
4-phytase
3.1.3.29
N-acylneuraminate-9-phosphatase
3.1.3.3
phosphoserine phosphatase
3.1.3.48
protein-tyrosine-phosphatase
3.1.3.75
phosphoethanolamine/phosphocholine phosphatase
3.1.3.8
3-phytase
|
–
–
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BS364502
KEGG:
R00582
MetaCyc:
RXN0-5114
SABIO-RK:
10330;
983
|
|
|
|
3-Amino-4-hydroxybenzoic_acid + N-acetyl-L-cysteine + O2 + H+ <=> grixazone_B + H2O + CO2
|
1.10.3.15
grixazone synthase
|
–
|
|
BRENDA:
BR51024
KEGG:
R10720
MetaCyc:
RXN-15414
|
|
|
|
NADP+ + dihydrozeatin <=> H+ + trans-zeatin + NADPH
|
1.3.1.69
zeatin reductase
|
–
|
|
BRENDA:
BR40541
KEGG:
R05702
MetaCyc:
ZEATIN-REDUCTASE-RXN
|
|
|
|
beta-cryptoxanthin + O2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> zeaxanthin + H2O + oxidized_ferredoxin
|
1.14
1.14.13
1.14.15.24
beta-carotene 3-hydroxylase
|
–
–
–
|
|
BRENDA:
BR49603
KEGG:
R07559
MetaCyc:
RXN-8026
|
|
|
|
geraniol + NAD+ <=> citral + NADH + H+
|
1.1.1.1
alcohol dehydrogenase
1.1.1.183
geraniol dehydrogenase (NADP+)
1.1.1.198
(+)-borneol dehydrogenase
1.1.1.347
geraniol dehydrogenase (NAD+)
1.1.1.90
aryl-alcohol dehydrogenase
|
–
–
–
–
–
|
|
BRENDA:
BR50498
KEGG:
R10308
MetaCyc:
RXN-11968
SABIO-RK:
13273
|
|
|
|
Pantetheine_4''-phosphate + H2O <=> pantetheine + phosphate
|
3.1.3
|
–
|
|
KEGG:
R10748
|
|
|
|
S-adenosyl-L-methionine + phenazine-1-carboxylic_acid <=> 5-methylphenazine-1-carboxylate + S-adenosyl-L-homocysteine
|
2.1.1.327
phenazine-1-carboxylate N-methyltransferase
|
–
|
|
BRENDA:
BR51748
KEGG:
R11533
MetaCyc:
RXN-11897
|
|
|
|
6-Oxocampestanol + O2 + NADPH <=> Cathasterone + NADP+ + H2O
|
1.14.13
|
–
|
|
KEGG:
R07430
|
|
|
|
3''''-Oxogentamicin_A2 + L-glutamate <=> 3''''-Amino-3''''-deoxygentamicin_A2 + 2-oxoglutarate
|
2.6.1
|
–
|
|
KEGG:
R11291
|
|
|
|
Terpendole_I + dimethylallyl_diphosphate <=> Terpendole_J + diphosphate
|
2.5.1
|
–
|
|
KEGG:
R10380
MetaCyc:
RXN-15961
|
|
|
|
gibberellin_a9 <=> 2,3-Dehydro-gibberellin_A9
|
1.14.11
|
–
|
|
KEGG:
R06349
|
|
|
|
dTDP-4-dehydro-6-deoxy-D-glucose <=> dTDP-4-dehydro-beta-L-rhamnose
|
5.1.3.13
dTDP-4-dehydrorhamnose 3,5-epimerase
|
–
|
|
BRENDA:
BR188
KEGG:
R06514
MetaCyc:
DTDPDEHYDRHAMEPIM-RXN
SABIO-RK:
2651
|
|
|
|
afzelechin + NADP+ + H2O <=> cis-3,4-leucopelargonidin + NADPH + H+
|
1.17.1.3
leucoanthocyanidin reductase
|
–
|
|
KEGG:
R06615
MetaCyc:
RXN-1481
|
|
|
|
DELTA5,7-avenasterol <=> isofucosterol
|
1.3.1.21
7-dehydrocholesterol reductase
|
–
|
|
KEGG:
R07487
|
|
|
|
theophylline + NADPH + O2 + H+ <=> 1-Methylxanthine + NADP+ + formaldehyde + H2O
|
1.14.13.179
methylxanthine N3-demethylase
|
–
|
|
KEGG:
R07976
MetaCyc:
RXN-13110
|
|
|
|
3-devinyl-3-(1-hydroxyethyl)chlorophyllide_a + ADP + oxidized_ferredoxin + phosphate <=> 3-devinyl-3-(1-hydroxyethyl)chlorophyllide_a + ATP + reduced_ferredoxin_[iron-sulfur]_cluster + H2O + H+
|
1.3.7.15
chlorophyllide a reductase
|
–
|
|
BRENDA:
BR51654
KEGG:
R09060
MetaCyc:
RXN-8786
|
|
|
|
2-deoxy-scyllo-inosamine + NADP+ <=> 3-amino-2,3-dideoxy-scyllo-inosose + NADPH + H+
|
1.1.1.329
2-deoxy-scyllo-inosamine dehydrogenase
|
–
|
|
BRENDA:
BR50138
KEGG:
R10130
MetaCyc:
RXN-13118
|
|
|
|
O-phospho-L-serine + 2-oxoglutarate <=> L-glutamate + 3-phosphohydroxypyruvate
|
2.6.1.52
phosphoserine transaminase
|
–
|
|
BRENDA:
BR47699
KEGG:
R04173
MetaCyc:
PSERTRANSAM-RXN
SABIO-RK:
3893
|
|
|
|
dTDP-4-dehydro-6-deoxy-D-glucose <=> dTDP-4-dehydro-6-deoxy-alpha-D-gulose
|
5.1.3.27
dTDP-4-dehydro-6-deoxy-D-glucose 3-epimerase
|
–
|
|
BRENDA:
BR50724
KEGG:
R06437
MetaCyc:
RXN-14707
|
|
|
|
echinenone + 2 reduced_ferredoxin_[iron-sulfur]_cluster + H+ + O2 <=> 3''-hydroxyechinenone + 2 oxidized_ferredoxin + H2O
|
1.14.13
1.14.15.24
beta-carotene 3-hydroxylase
|
–
–
|
|
BRENDA:
BS416968;
BS416969
KEGG:
R07561;
R07562
|
|
|
|
oxalosuccinate + H+ <=> 2-oxoglutarate + CO2
|
1.1.1.42
isocitrate dehydrogenase (NADP+)
|
–
|
|
BRENDA:
BR48779
KEGG:
R00268
MetaCyc:
RXN-8642
SABIO-RK:
241
|
|
|
|
100-2 + dTDP-L-rhodinose <=> aggreticin + dTDP
|
not assigned
|
–
|
|
KEGG:
R06667
|
|
|
|
geranylgeranyl_diphosphate <=> diphosphate + casbene
|
4.2.3.8
casbene synthase
|
–
|
|
BRENDA:
BR48355
KEGG:
R02064
MetaCyc:
CASBENE-SYNTHASE-RXN
|
|
|
|
D-mannose_6-phosphate <=> beta-D-fructose_6-phosphate
|
5.3.1.8
mannose-6-phosphate isomerase
5.3.1.9
glucose-6-phosphate isomerase
|
–
–
|
|
BRENDA:
BR239
KEGG:
R00772;
R01819
MetaCyc:
MANNPISOM-RXN
SABIO-RK:
1124
|
|
|
|
(2E,6E)-farnesyl_diphosphate <=> pentalenene + diphosphate
|
4.2.3.7
pentalenene synthase
|
–
|
|
BRENDA:
BR48354
KEGG:
R02305
MetaCyc:
PENTALENENE-SYNTHASE-RXN
|
|
|
|
L-2-aminoadipate_adenylate + Holo-Lys2 <=> alpha-Aminoadipoyl-S-acyl_enzyme + AMP
|
1.2.1.95
L-2-aminoadipate reductase
|
–
|
|
KEGG:
R04863
|
|
|
|
(2E,6E)-farnesyl_diphosphate <=> (-)-vetispiradiene + diphosphate
|
4.2.3.21
vetispiradiene synthase
|
–
|
|
BRENDA:
BR48352
KEGG:
R06523
MetaCyc:
RXN-4823
|
|
|
|
dTDP-4-ethylamino-3-O-methyl-2,4-dideoxy-L-threo-pentopyranose + Calicheamicin_PsAg <=> dTDP + Calicheamicin_alpha1(I)
|
2.4.2
|
–
|
|
KEGG:
R11420
|
|
|
|
7,9,12-Decaketide_intermediate_2 <=> 7,9,12-Decaketide_intermediate_3 + 2 H2O
|
4.2.1
|
–
|
|
KEGG:
R09266
|
|
|
|
alpha-D-glucose_6-phosphate <=> beta-D-fructose_6-phosphate
|
5.3.1.9
glucose-6-phosphate isomerase
|
–
|
|
KEGG:
R02740
|
|
|
|
dTDP-4-dehydro-6-deoxy-D-glucose <=> dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + H2O
|
4.2.1.159
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase
|
–
|
|
BRENDA:
BR51535
KEGG:
R05518
MetaCyc:
RXN-16567
|
|
|
|
dimethylallyl_diphosphate + 5,10-dihydrophenazine_1-carboxylate <=> diphosphate + 5,10-dihydro-9-dimethylallylphenazine_1-carboxylate
|
2.5.1.121
5,10-dihydrophenazine-1-carboxylate 9-dimethylallyltransferase
|
–
|
|
BRENDA:
BR50879
KEGG:
R10966
MetaCyc:
RXN-15417
|
|
|
|
S-adenosyl-L-methionine + protein_C-terminal_S-farnesyl-L-cysteine <=> S-adenosyl-L-homocysteine + protein_C-terminal_S-farnesyl-L-cysteine_methyl_ester
|
2.1.1.100
protein-S-isoprenylcysteine O-methyltransferase
|
–
|
|
BRENDA:
BR43859
KEGG:
R04496
|
|
|
|
tetracycline + O2 + Cl- + FADH2 <=> 7-chlorotetracycline + H2O + FAD + H+
|
1.14.19.49
tetracycline 7-halogenase
|
–
|
|
BRENDA:
BR51837
KEGG:
R11478
MetaCyc:
RXN-17996
|
|
|
|
S-adenosyl-L-methionine + (S)-corytuberine <=> S-adenosyl-L-homocysteine + (S)-magnoflorine + H+
|
2.1.1.337
reticuline N-methyltransferase
|
–
|
|
BRENDA:
BR51955;
BS438442
KEGG:
R08791
MetaCyc:
RXN-9315
|
|
|
|
glycine + acceptor <=> cyanide + CO2 + reduced_acceptor
|
1.4.99.5
glycine dehydrogenase (cyanide-forming)
|
–
|
|
BRENDA:
BR36887
KEGG:
R00374;
R05704
MetaCyc:
1.4.99.5-RXN
|
|
|
|
7,9,12-Decaketide_intermediate_1 + NADPH + H+ <=> 7,9,12-Decaketide_intermediate_2 + NADP+
|
1.1.1
|
–
|
|
KEGG:
R09263
|
|
|
|
tryprostatin_A + reduced_flavodoxin + O2 <=> fumitremorgin_C + flavin + 2 H2O
|
1.14.19.71
fumitremorgin C synthase
|
–
|
|
BRENDA:
BR50590
KEGG:
R10416
|
|
|
|
(+)-trans-carveol + NAD+ <=> (S)-carvone + NADH + H+
|
1.1.1.275
(+)-trans-carveol dehydrogenase
|
–
|
|
BRENDA:
BR47616
KEGG:
R06117
MetaCyc:
RXN-9397
|
|
|
|
S-adenosyl-L-methionine + a_3-vinyl_bacteriochlorophyllide_d <=> S-adenosyl-L-homocysteine + a_bacteriochlorophyllide_c
|
2.1.1.333
bacteriochlorophyllide d C-20 methyltransferase
|
–
|
|
BRENDA:
BR51854
KEGG:
R09063
|
|
|
|
7-chloro-L-tryptophan + O2 <=> 2-imino-3-(7-chloroindol-3-yl)propanoate + H2O2 + H+
|
1.4.3.23
7-chloro-L-tryptophan oxidase
|
–
|
|
BRENDA:
BR49130
KEGG:
R09560
MetaCyc:
RXN-10843
|
|
|
|
tabersonine <=> 19-Hydroxytabersonine
|
not assigned
|
–
|
|
KEGG:
R05872
|
|
|
|
Caffeine + NADPH + O2 + H+ <=> paraxanthine + NADP+ + formaldehyde + H2O
|
1.14.13.128
7-methylxanthine demethylase
1.14.13.179
methylxanthine N3-demethylase
1.14.14.1
unspecific monooxygenase
|
–
–
–
|
|
BRENDA:
BS417832
KEGG:
R07939
MetaCyc:
RXN-13106
|
|
|
|
S-adenosyl-L-methionine + 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)-tetracenomycin_C <=> 8-demethyl-8-(2,3-O-dimethyl-alpha-L-rhamnosyl)-tetracenomycin_C + S-adenosyl-L-homocysteine + H+
|
2.1.1.306
8-demethyl-8-(2-methoxy-alpha-L-rhamnosyl)tetracenomycin-C 3'-O-methyltransferase
|
–
|
|
BRENDA:
BR50858
KEGG:
R10957
MetaCyc:
RXN-15404
|
|
|
|
3,5-diphosphomevalonate + H+ <=> isopentenyl_phosphate + CO2 + phosphate
|
4.1.1.110
bisphosphomevalonate decarboxylase
|
–
|
|
BRENDA:
BR52424
KEGG:
R10781
MetaCyc:
RXN-15649
|
|
|
|
L-arogenate + NAD+ <=> L-tyrosine + CO2 + NADH
|
1.3.1.12
prephenate dehydrogenase
1.3.1.43
arogenate dehydrogenase
1.3.1.78
arogenate dehydrogenase (NADP+)
1.3.1.79
arogenate dehydrogenase [NAD(P)+]
|
–
–
–
–
|
|
BRENDA:
BR36825
KEGG:
R00732
MetaCyc:
CYCLOHEXADIENYL-DEHYDROGENASE-RXN;
RXN-14476_WOP
SABIO-RK:
1095
|
|
|
|
2'',7-Dihydroxy-4'',5''-methylenedioxyisoflavone + NADPH + H+ <=> (+)-Sophorol + NADP+
|
1.3.1.45
2'-hydroxyisoflavone reductase
|
–
|
|
KEGG:
R07747
|
|
|
|
paromomycin <=> paromomycin
|
5.1.3
|
–
|
|
KEGG:
R11286
|
|
|
|
futalosine + H2O <=> dehypoxanthine_futalosine + hypoxanthine
|
3.2.2.26
futalosine hydrolase
|
–
|
|
BRENDA:
BR48967
KEGG:
R08587
MetaCyc:
RXN-9780
|
|
|
|
N-acetylphosphinothricin + H2O <=> Phosphinothricin + acetate
|
not assigned
|
–
|
|
KEGG:
R08874
|
|
|
|
L-tyrosine + O2 + reduced_flavodoxin <=> N-hydroxy-L-tyrosine + flavin + H2O
|
1.14.14.36
tyrosine N-monooxygenase
|
–
|
|
BRENDA:
BR36762
KEGG:
R00730
|
|
|
|
6-phospho-D-glucono-1,5-lactone + H2O <=> H+ + 6-phosphogluconate
|
3.1.1.31
6-phosphogluconolactonase
|
–
|
|
BRENDA:
BR10654
KEGG:
R02035
MetaCyc:
6PGLUCONOLACT-RXN
SABIO-RK:
109
|
|
|
|
ferruginol + reduced_flavodoxin + O2 <=> salviol + flavin + H2O
|
1.14.14.62
salviol synthase
|
–
|
|
BRENDA:
BR52294
KEGG:
R11974
|
|
|
|
Hygrine <=> tropinone
|
not assigned
|
–
|
|
KEGG:
R06733
|
|
|
|
(4R)-ipsdienol + NADP+ <=> ipsdienone + NADPH + H+
|
1.1.1.386
ipsdienol dehydrogenase
|
–
|
|
BRENDA:
BR51210
KEGG:
R10919
MetaCyc:
RXN-15051
SABIO-RK:
14711
|
|
|
|
O-acetyl-L-serine + Hydroxyurea <=> O-ureido-L-serine + acetate + H+
|
2.5.1.51
beta-pyrazolylalanine synthase
2.6.99.3
O-ureido-L-serine synthase
|
–
–
|
|
BRENDA:
BR50676
KEGG:
R10461
MetaCyc:
RXN-14458
|
|
|
|
9beta-pimara-7,15-diene + reduced_flavodoxin + O2 <=> 9beta-pimara-7,15-diene-3beta-ol + flavin + H2O
|
1.14.14.68
syn-pimaradiene 3-monooxygenase
|
–
|
|
BRENDA:
BR52300
KEGG:
R11980
|
|
|
|
5''''-phosphoribostamycin + H2O <=> ribostamycin + phosphate
|
3.1.3.88
5''-phosphoribostamycin phosphatase
|
–
|
|
BRENDA:
BR50198
KEGG:
R08899
MetaCyc:
RXN-13204
|
|
|
|
O-phospho-L-serine + L-glutamate <=> N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate + phosphate
|
2.5.1.140
N-(2-amino-2-carboxyethyl)-L-glutamate synthase
|
–
|
|
BRENDA:
BR52061
KEGG:
R11705
MetaCyc:
RXN-18395
|
|
|
|
S-adenosyl-L-methionine + sterigmatocystin <=> 8-O-methylsterigmatocystin + S-adenosyl-L-homocysteine + H+
|
2.1.1.110
sterigmatocystin 8-O-methyltransferase
|
–
|
|
BRENDA:
BR43870
KEGG:
R03111
MetaCyc:
2.1.1.110-RXN
|
|
|
|
fumigaclavine_A + dimethylallyl_diphosphate <=> fumigaclavine_C + diphosphate
|
2.5.1.100
fumigaclavine A dimethylallyltransferase
|
–
|
|
BRENDA:
BR50300
KEGG:
R10201
MetaCyc:
RXN-11367
|
|
|
|
methyl_ecgonine + benzoyl-CoA <=> cocaine + CoA
|
2.3.1
|
–
|
|
KEGG:
R08430
MetaCyc:
RXN-9201
|
|
|
|
S-adenosyl-L-methionine + erythromycin_D <=> S-adenosyl-L-homocysteine + erythromycin_B + H+
|
2.1.1.254
erythromycin 3''-O-methyltransferase
|
–
|
|
BRENDA:
BR50050
KEGG:
R05532
MetaCyc:
RXN-12924
|
|
|
|
formononetin + reduced_flavodoxin + O2 <=> 2''-hydroxyformononetin + flavin + H2O
|
1.14.14.89
4'-methoxyisoflavone 2'-hydroxylase
1.14.14.90
isoflavone 2'-hydroxylase
|
–
–
|
|
BRENDA:
BR29142
KEGG:
R06560
|
|
|
|
acetyl-CoA + (3Z)-hex-3-en-ol <=> cis-3-hexen-1-yl_acetate + CoA
|
2.3.1.195
(Z)-3-hexen-1-ol acetyltransferase
2.3.1.224
acetyl-CoA-benzylalcohol acetyltransferase
2.3.1.84
alcohol O-acetyltransferase
|
–
–
–
|
|
BRENDA:
BR49455
KEGG:
R09631
MetaCyc:
RXN-11852
SABIO-RK:
14832
|
|
|
|
Polyphosphate + alpha-D-glucose <=> Polyphosphate + alpha-D-glucose_6-phosphate
|
2.7.1.63
polyphosphate---glucose phosphotransferase
|
–
|
|
KEGG:
R02189
|
|
|
|
5-amino-2,6-dioxy-4-(5'-phosphoribitylamino)pyrimidine + NADP+ <=> 5-amino-6-(5-phospho-D-ribosylamino)uracil + NADPH + H+
|
1.1.1.193
5-amino-6-(5-phosphoribosylamino)uracil reductase
|
–
|
|
BRENDA:
BR29246
KEGG:
R03458
MetaCyc:
RIBOFLAVINSYNREDUC-RXN
|
|
|
|
S-adenosyl-L-methionine + Zymosterol <=> H+ + S-adenosyl-L-homocysteine + fecosterol
|
2.1.1.142
cycloartenol 24-C-methyltransferase
2.1.1.143
24-methylenesterol C-methyltransferase
2.1.1.41
sterol 24-C-methyltransferase
|
–
–
–
|
|
BRENDA:
BR43897
KEGG:
R04427
MetaCyc:
RXN3O-178
SABIO-RK:
4114
|
|
|
|
S-adenosyl-L-methionine + Fe-coproporphyrin_III <=> heme + CO2 + 5''-deoxyadenosine + L-methionine
|
1.3.98.6
AdoMet-dependent heme synthase
|
–
|
|
BRENDA:
BR52577
KEGG:
R12002
MetaCyc:
RXN-15808
|
|
|
|
atropine + H2O <=> H+ + tropate + Tropine
|
3.1.1.10
tropinesterase
|
–
|
|
BRENDA:
BR15898;
BS415950
KEGG:
R03563;
R03564
MetaCyc:
TROPINESTERASE-RXN
|
|
|
|
bisdemethoxycurcumin <=> demethoxycurcumin
|
not assigned
|
–
|
|
KEGG:
R08811
|
|
|
|
geranyl_diphosphate + 1,4-dihydroxy-2-naphthoate <=> a_demethylmenaquinol + diphosphate + CO2
|
2.5.1.74
1,4-dihydroxy-2-naphthoate polyprenyltransferase
|
–
|
|
BRENDA:
BR49120
KEGG:
R10757
|
|
|
|
D-glyceraldehyde_3-phosphate + L-arginine <=> N2-(2-carboxyethyl)-L-arginine + phosphate + H+
|
2.5.1.66
N2-(2-carboxyethyl)arginine synthase
|
–
|
|
BRENDA:
BR48519
KEGG:
R05465
MetaCyc:
2.5.1.66-RXN
|
|
|
|
eriodictyol + reduced_flavodoxin + O2 <=> luteolin + flavin + H2O
|
1.14.14.162
flavanone 2-hydroxylase
1.14.19.76
flavone synthase II
|
–
–
|
|
BRENDA:
BS373155
KEGG:
R12279
|
|
|
|
palustradiene <=> Palustradienol
|
1.14.13
|
–
|
|
KEGG:
R09108
|
|
|
|
S-adenosyl-L-methionine + 3-Hydroxy-5-iodo-2-methoxyorsellinate-[acp] <=> S-adenosyl-L-homocysteine + 5-Iodo-2,3-dimethoxyorsellinate-[acp]
|
2.1.1
|
–
|
|
KEGG:
R11416
|
|
|
|
protoviolaceinate + O2 + NADH + H+ <=> violaceinate + NAD+ + H2O
|
1.14.13.224
violacein synthase
|
–
|
|
BRENDA:
BR51738-a
KEGG:
R11373
MetaCyc:
RXN-13342_WOP
|
|
|
|
copalyl_diphosphate <=> pimara-8(14),15-diene + diphosphate
|
4.2.3.147
pimaradiene synthase
|
–
|
|
BRENDA:
BR51088
KEGG:
R06299
MetaCyc:
RXN-15704
|
|
|
|
15-cis-phytoene + plastoquinone <=> 15,9''-di-cis-phytofluene + plastoquinol
|
1.3.5.5
15-cis-phytoene desaturase
|
–
|
|
BRENDA:
BR49667
KEGG:
R09653
MetaCyc:
RXN-12243
|
|
|
|
2,3-Dehydro-UWM6 + L-isoleucine <=> Jadomycin_A + CO2 + H2O
|
not assigned
|
–
|
|
KEGG:
R09344
|
|
|
|
chlorophyll_a + H+ <=> pheophytin_a + Mg2+
|
4.99.1.10
magnesium dechelatase
|
–
|
|
BRENDA:
BR52076
KEGG:
R08584
MetaCyc:
RXN-8378
|
|
|
|
L-gamma-Glutamyl-(3R)-L-beta-ethynylserine + H2O <=> L-beta-Ethynylserine + L-glutamate
|
not assigned
|
–
|
|
KEGG:
R12412
|
|
|
|
NDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose <=> NDP-2-amino-4-oxo-2,6-dideoxy-D-galactose
|
not assigned
|
–
|
|
KEGG:
R11432
|
|
|
|
N6-(delta2-Isopentenyl)-adenosine_5''-monophosphate + H2O <=> N6-isopentenyladenosine + phosphate
|
not assigned
|
–
|
|
KEGG:
R08069
|
|
|
|
DELTA1-piperideine + Pelletierine <=> L-(+)-Anaferine
|
not assigned
|
–
|
|
KEGG:
R05130
|
|
|
|
gardneral <=> gardneral
|
not assigned
|
–
|
|
KEGG:
R05826
MetaCyc:
RXN-8225
|
|
|
|
tRNA_containing_6-isopentenyladenosine <=> cis-Prenyl-tRNA
|
not assigned
|
–
|
|
KEGG:
R08077
|
|
|
|
S-Anthraniloyl-L-cysteinyl-protein + malonyl-CoA <=> 2-aminobenzoylacetyl-CoA + CO2 + S-Anthraniloyl-L-cysteinyl-protein
|
2.3.1.262
anthraniloyl-CoA anthraniloyltransferase
|
–
|
|
KEGG:
R11587
|
|
|
|
narbomycin + 4 reduced_ferredoxin_[iron-sulfur]_cluster + 4 H+ + 2 O2 <=> novapikromyin + 4 oxidized_ferredoxin + 2 H2O
|
1.14.15.33
pikromycin synthase
|
–
|
|
BRENDA:
BR50919
KEGG:
R10627
|
|
|
|
L-tyrosine + pC3'p + ATP <=> L-Tyrosyl-[pcp] + AMP + diphosphate
|
not assigned
|
–
|
|
KEGG:
R06751
|
|
|
|
baccatin_III + (3R)-3-amino-3-phenylpropanoyl-CoA <=> 3''-N-Debenzoyl-2''-deoxytaxol + CoA
|
2.3.2
|
–
|
|
KEGG:
R08172
|
|
|
|
17-O-acetylnorajmaline + H2O <=> norajmaline + acetate + H+
|
3.1.1.80
acetylajmaline esterase
|
–
|
|
BRENDA:
BR48752
KEGG:
R05880
MetaCyc:
RXN-8220
|
|
|
|
3''-N-Debenzoyl-2''-deoxytaxol + reduced_acceptor + O2 <=> 3''-N-Debenzoyltaxol + acceptor + H2O
|
1.14
|
–
|
|
KEGG:
R08173
|
|
|
|
divinyl_protochlorophyllide_a + NADPH <=> divinyl_chlorophyllide_a + NADP+
|
1.3.1.33
protochlorophyllide reductase
|
–
|
|
BRENDA:
BS386455
KEGG:
R06286
|
|
|
|
(S)-beta-Tyrosyl-[pcp] <=> 3-(4-Hydroxyphenyl)-3-oxopropanoyl-[pcp]
|
not assigned
|
–
|
|
KEGG:
R11369
|
|
|
|
dTDP-4-oxo-5-C-methyl-L-rhamnose <=> dTDP-4-amino-4,6-dideoxy-5-C-methyl-D-allose
|
not assigned
|
–
|
|
KEGG:
R11464
|
|
|
|
naringenin + reduced_flavodoxin + O2 <=> eriodictyol + flavin + H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
1.14.14.82
flavonoid 3'-monooxygenase
|
–
–
|
|
BRENDA:
BS288543;
BS372123
KEGG:
R02442
|
|
|
|
2,3-Epoxymenaquinone + peptidyl-4-carboxyglutamate + H2O <=> menaquinol + peptidyl-glutamate + CO2 + O2
|
4.1.1.90
peptidyl-glutamate 4-carboxylase
|
–
|
|
KEGG:
R09991
|
|
|
|
succinate + ITP + CoA <=> succinyl-CoA + IDP + phosphate
|
6.2.1.4
succinate---CoA ligase (GDP-forming)
|
–
|
|
KEGG:
R00727
MetaCyc:
RXN-12511
|
|
|
|
5-enolpyruvylshikimate_3-phosphate <=> phosphate + chorismate
|
4.2.3.5
chorismate synthase
|
–
|
|
BRENDA:
BR16094
KEGG:
R01714
MetaCyc:
CHORISMATE-SYNTHASE-RXN
SABIO-RK:
1826
|
|
|
|
(3R,4R)-7,2''-dihydroxy-4''-methoxyisoflavanol + NADP+ <=> vestitone + NADPH + H+
|
1.1.1.348
(3R)-2'-hydroxyisoflavanone reductase
|
–
|
|
BRENDA:
BS421737
KEGG:
R07737
MetaCyc:
RXN-3601
|
|
|
|
7-methyl-3-oxooct-6-enoyl-CoA + CoA <=> 5-methylhex-4-enoyl-CoA + acetyl-CoA
|
2.3.1
2.3.1.16
acetyl-CoA C-acyltransferase
|
–
–
|
|
BRENDA:
BS417874
KEGG:
R08091
MetaCyc:
RXN-11917
|
|
|
|
(3S)-2,3-epoxy-2,3-dihydrosqualene <=> cucurbitadienol
|
5.4.99.33
cucurbitadienol synthase
|
–
|
|
BRENDA:
BR49628
KEGG:
R09688
MetaCyc:
RXN-12327
|
|
|
|
(6E)-8-methylnon-6-enoyl-CoA + vanillylamine <=> capsaicin + CoA + H+
|
2.3.2.35
capsaicin synthase
|
–
|
|
BRENDA:
BR53074
KEGG:
R12626
MetaCyc:
RXN-8927
|
|
|
|
(E)-4-hydroxy-3-methylbut-2-en-1-yl_diphosphate + oxidized_ferredoxin + H2O <=> 2-C-methyl-D-erythritol_2,4-cyclodiphosphate + reduced_ferredoxin_[iron-sulfur]_cluster + H+
|
1.17.7.1
(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin)
|
–
|
|
BRENDA:
BR47612
KEGG:
R08689
MetaCyc:
RXN0-882
|
|
|
|
(2E,6E)-farnesyl_diphosphate <=> amorpha-4,11-diene + diphosphate
|
4.2.3.24
amorpha-4,11-diene synthase
|
–
|
|
BRENDA:
BR48696
KEGG:
R07630
MetaCyc:
RXN-8046
|
|
|
|
Ansamitocinoside_P-3 + Carbamoyl_phosphate <=> 4''''-O-Carbamoyl_ansamitocinoside_P-3 + phosphate
|
2.1.3
|
–
|
|
KEGG:
R09858
|
|
|
|
pantothenate + H2O <=> beta-Alanine + (R)-pantoate
|
3.5.1.22
pantothenase
|
–
|
|
BRENDA:
BR19240;
BS116222
KEGG:
R02474
MetaCyc:
PANTOTHENASE-RXN
|
|
|
|
3-amino-4,7-dihydroxycoumarin <=> 3-Amino-4,7-dihydroxy-8-chlorocoumarin
|
not assigned
|
–
|
|
KEGG:
R06766
|
|
|
|
(9Z,11E,13S,15Z)-13-hydroperoxy-9,11,15-octadecatrienoate <=> 12-oxododecenoic_acid + cis-3-hexenal
|
4.2.1.M17
4.2.1.M19
|
–
–
|
|
KEGG:
R07870
MetaCyc:
RXN-1345
|
|
|
|
6alpha-Hydroxycampestanol <=> 6-Oxocampestanol
|
not assigned
|
–
|
|
KEGG:
R07468
|
|
|
|
Penicillin_N + 2-oxoglutarate + O2 <=> deacetoxycephalosporin_C + succinate + CO2 + H2O
|
1.14.20.1
deacetoxycephalosporin-C synthase
|
–
|
|
BRENDA:
BR40542
KEGG:
R05301
MetaCyc:
1.14.20.1-RXN
SABIO-RK:
4910
|
|
|
|
gentamicin_X2 + methylcobalamin + S-adenosyl-L-methionine + H+ + e- <=> geneticin + Cobalamin + 5''-Deoxyadenosine + L-methionine
|
2.1.1
|
–
|
|
KEGG:
R11294
|
|
|
|
S-adenosyl-L-methionine + 16-methoxy-2,3-dihydro-3-hydroxytabersonine <=> S-adenosyl-L-homocysteine + deacetoxyvindoline + H+
|
2.1.1.99
3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase
|
–
|
|
BRENDA:
BR43938
KEGG:
R04013
MetaCyc:
2.1.1.99-RXN
|
|
|
|
(1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate + O2 <=> (10aS)-10,10a-dihydrophenazine-1-carboxylate + H2O2
|
1.10.3.16
dihydrophenazinedicarboxylate synthase
|
–
|
|
BRENDA:
BR51795
KEGG:
R11491
MetaCyc:
RXN-17690
|
|
|
|
O-acetyl-L-serine + Sulfide <=> L-cysteine + acetate + H+
|
2.5.1.47
cysteine synthase
2.5.1.49
O-acetylhomoserine aminocarboxypropyltransferase
2.5.1.65
O-phosphoserine sulfhydrylase
4.2.1.22
cystathionine beta-synthase
4.2.1.50
pyrazolylalanine synthase
4.4.1.9
L-3-cyanoalanine synthase
|
–
–
–
–
–
–
|
|
BRENDA:
BR47463;
BS370451
KEGG:
R00897
MetaCyc:
ACSERLY-RXN
SABIO-RK:
1220;
9651
|
|
|
|
myrcene + reduced_flavodoxin + O2 <=> (4R)-ipsdienol + flavin + H2O
|
1.14.14.31
ipsdienol synthase
|
–
|
|
BRENDA:
BR51495
KEGG:
R11055
|
|
|
|
Cinnamic_acid + NAD+ + H2O <=> benzoate + acetate + NADH + H+
|
not assigned
|
–
|
|
KEGG:
R01426
MetaCyc:
RXN-9336
|
|
|
|
2-Methyl-3-n-amyl-dihydropyrrole + FAD <=> 2-Methyl-3-n-amyl-pyrrole + FADH2
|
not assigned
|
–
|
|
KEGG:
R11661
|
|
|
|
alpha-3,4''-anhydrovinblastine + H2O <=> vinblastine
|
not assigned
|
–
|
|
KEGG:
R05859
MetaCyc:
RXN-12023
|
|
|
|
2-oxoglutarate + CoA + NAD+ <=> succinyl-CoA + CO2 + NADH
|
1.2.1.ak
1.2.4.2
oxoglutarate dehydrogenase (succinyl-transferring)
1.2.4.4
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
1.8.1.4
dihydrolipoyl dehydrogenase
2.3.1.61
dihydrolipoyllysine-residue succinyltransferase
|
–
–
–
–
–
|
|
KEGG:
R08549
MetaCyc:
2OXOGLUTARATEDEH-RXN
SABIO-RK:
8163
|
|
|
|
L-tyrosine + H2O2 <=> L-Dopa + H2O
|
1.11.2.6
L-tyrosine peroxygenase
1.14.18.1
tyrosinase
|
–
–
|
|
BRENDA:
BR53064
KEGG:
R12611
MetaCyc:
RXN-21208
|
|
|
|
homoisocitrate + NAD+ <=> 2-oxoadipate + CO2 + NADH
|
1.1.1.286
isocitrate---homoisocitrate dehydrogenase
1.1.1.42
isocitrate dehydrogenase (NADP+)
1.1.1.87
homoisocitrate dehydrogenase
|
–
–
–
|
|
BRENDA:
BR48021
KEGG:
R01934
MetaCyc:
RXN-7970
SABIO-RK:
1988
|
|
|
|
(+)-cis-isopulegone <=> (R)-pulegone
|
5.3.3
|
–
|
|
KEGG:
R06418
MetaCyc:
RXN-5162
|
|
|
|
Tetrahydroalstonine + reduced_flavodoxin + O2 <=> Alstonine + flavin + 2 H2O + 2 H+
|
1.14.14
|
–
|
|
KEGG:
R12282
|
|
|
|
Jadomycin_A <=> Jadomycin_B
|
2.4.1
|
–
|
|
KEGG:
R06670
|
|
|
|
(22S,24R)-22-hydroxy-5alpha-ergostan-3-one + reduced_flavodoxin + O2 <=> 3-dehydro-6-deoxoteasterone + flavin + H2O
|
1.14.14.147
3-epi-6-deoxocathasterone 23-monooxygenase
|
–
|
|
BRENDA:
BR49135
KEGG:
R07791
|
|
|
|
Zymosterol + NADP+ <=> H+ + zymosterone + NADPH
|
1.1.1.270
3beta-hydroxysteroid 3-dehydrogenase
1.1.1.51
3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62
17beta-estradiol 17-dehydrogenase
|
–
–
–
|
|
BRENDA:
BS374946
KEGG:
R12405
MetaCyc:
RXN66-319
|
|
|
|
(2E,6E)-farnesyl_diphosphate + isopentenyl_diphosphate <=> all-trans-hexaprenyl_diphosphate + diphosphate
|
2.5.1.82
hexaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]
2.5.1.83
hexaprenyl diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]
|
–
–
|
|
BRENDA:
BR49313
KEGG:
R09245
MetaCyc:
TRANS-PENTAPRENYLTRANSFERASE-RXN
|
|
|
|
butyryl-CoA + NAD+ <=> crotonyl-CoA + NADH + H+
|
1.3.1.44
trans-2-enoyl-CoA reductase (NAD+)
1.3.1.9
enoyl-[acyl-carrier-protein] reductase (NADH)
|
–
–
|
|
BRENDA:
BS258558
KEGG:
R01171
MetaCyc:
RXN-12558
SABIO-RK:
1408
|
|
|
|
4-coumaroyl-CoA + malonyl-CoA + H2O + H+ <=> CoA + bisdemethoxycurcumin + CO2
|
2.3.1.211
bisdemethoxycurcumin synthase
|
–
|
|
BRENDA:
BR50403
KEGG:
R10233
MetaCyc:
RXN-13958
|
|
|
|
dihydrochanoclavine-I_aldehyde + NADP+ <=> chanoclavine-I_aldehyde + NADPH + H+
|
1.3.1.100
chanoclavine-I aldehyde reductase
|
–
|
|
BRENDA:
BR50507
KEGG:
R12090
MetaCyc:
RXN-13476
|
|
|
|
D-glucose_6-phosphate <=> 2-deoxy-scyllo-inosose + phosphate
|
4.2.3.124
2-deoxy-scyllo-inosose synthase
|
–
|
|
BRENDA:
BR50122
KEGG:
R08617
MetaCyc:
RXN-13116
SABIO-RK:
12961
|
|
|
|
4-methylsulfanyl-2-oxobutanoate + acetyl-CoA + H2O <=> 2-[(2''-methylsulfanyl)ethyl]malate + CoA + H+
|
2.3.3.17
methylthioalkylmalate synthase
|
–
|
|
BRENDA:
BS438092
KEGG:
R08619
MetaCyc:
RXN-2202
|
|
|
|
1-Methylpyrrolinium <=> methyl_ecgonine
|
not assigned
|
–
|
|
KEGG:
R08429
|
|
|
|
Deacetylcolchicine + acetyl-CoA <=> H+ + Colchicine + CoA
|
2.3.1
|
–
|
|
KEGG:
R08453
MetaCyc:
RXN-9210
|
|
|
|
S-adenosyl-L-methionine + delta-tocopherol <=> S-adenosyl-L-homocysteine + beta-tocopherol + H+
|
2.1.1.95
tocopherol C-methyltransferase
|
–
|
|
BRENDA:
BR52800
KEGG:
R07504
MetaCyc:
RXN-2562
|
|
|
|
(S)-2-amino-6-oxohexanoate + NADP+ + H2O <=> L-2-aminoadipate + NADPH + H+
|
1.2.1.31
L-aminoadipate-semialdehyde dehydrogenase
|
–
|
|
BRENDA:
BR29399
KEGG:
R03103
MetaCyc:
1.2.1.31-RXN
SABIO-RK:
2941
|
|
|
|
(3S)-2,3-epoxy-2,3-dihydrosqualene <=> thalianol
|
5.4.99.31
thalianol synthase
|
–
|
|
BRENDA:
BR49626
KEGG:
R09709
MetaCyc:
RXN-9630
|
|
|
|
N3-fumaroyl-L-2,3-diaminopropanoic_acid + L-glutamine + ATP + H2O <=> N3-fumarylcarboxyamido-L-2,3-diaminopropionic_acid + L-glutamate + ADP + phosphate
|
6.3.5
|
–
|
|
KEGG:
R12352
|
|
|
|
sinapyl_alcohol + NADP+ <=> sinapaldehyde + NADPH + H+
|
1.1.1.195
cinnamyl-alcohol dehydrogenase
1.1.1.2
alcohol dehydrogenase (NADP+)
|
–
–
|
|
BRENDA:
BS187664
KEGG:
R03918
MetaCyc:
RXN-1125
SABIO-RK:
3663
|
|
|
|
trans-zeatin + UDP-D-xylose <=> H+ + O-beta-D-xylosylzeatin + UDP
|
2.4.1.203
trans-zeatin O-beta-D-glucosyltransferase
2.4.2.40
zeatin O-beta-D-xylosyltransferase
|
–
–
|
|
BRENDA:
BR47530
KEGG:
R02119
MetaCyc:
ZEATIN-O-BETA-D-XYLOSYLTRANSFERASE-RXN
SABIO-RK:
2109;
9368
|
|
|
|
H+ + 4-coumaroyl-CoA + malonyl-CoA <=> naringenin_chalcone + CO2 + CoA
|
2.3.1.159
acridone synthase
2.3.1.74
chalcone synthase
|
–
–
|
|
BRENDA:
BR44076
KEGG:
R01613
MetaCyc:
NARINGENIN-CHALCONE-SYNTHASE-RXN
SABIO-RK:
1758
|
|
|
|
Pelletierine <=> N-Methylpelletierine
|
not assigned
|
–
|
|
KEGG:
R05131
|
|
|
|
daunorubicin + NADPH + H+ + O2 <=> doxorubicin + NADP+ + H2O
|
1.14.13.181
13-deoxydaunorubicin hydroxylase
|
–
|
|
BRENDA:
BS421946
KEGG:
R06690
MetaCyc:
RXN-14855
|
|
|
|
vinblastine <=> vincristine
|
not assigned
|
–
|
|
KEGG:
R05860
|
|
|
|
chorismate + L-glutamine <=> (2S)-2-amino-4-deoxy-chorismate + L-glutamate
|
2.6.1.85
aminodeoxychorismate synthase
2.6.1.86
2-amino-4-deoxychorismate synthase
|
–
–
|
|
BRENDA:
BR48884
KEGG:
R08956
MetaCyc:
RXN-9028
SABIO-RK:
15416
|
|
|
|
13-dihydrodaunorubicin + NADPH + H+ + O2 <=> daunorubicin + NADP+ + H2O
|
1.14.13.181
13-deoxydaunorubicin hydroxylase
|
–
|
|
BRENDA:
BR50585
KEGG:
R06689
MetaCyc:
RXN-14830
|
|
|
|
NAD+ + bilirubin <=> Biliverdin + NADH + H+
|
1.3.1.24
biliverdin reductase
|
–
|
|
BRENDA:
BR40361-a
KEGG:
R02391
MetaCyc:
BILIVERDIN-REDUCTASE-RXN_WOP
SABIO-RK:
2333
|
|
|
|
(S)-N-methylcoclaurine + reduced_flavodoxin + O2 <=> (S)-3''-hydroxy-N-methylcoclaurine + flavin + H2O
|
1.14.14.102
N-methylcoclaurine 3'-monooxygenase
|
–
|
|
BRENDA:
BR29147
KEGG:
R05732
|
|
|
|
2,3-Dehydro-gibberellin_A9 <=> gibberellin_GA7
|
1.14.11
|
–
|
|
KEGG:
R06350
|
|
|
|
L-tryptophan + O2 <=> H+ + 2-imino-3-(indol-3-yl)propanoate + H2O2
|
1.4.3
1.4.3.23
7-chloro-L-tryptophan oxidase
|
–
–
|
|
BRENDA:
BS440306
KEGG:
R11119
MetaCyc:
RXN-10922
|
|
|
|
deoxyshikonin <=> shikonin
|
not assigned
|
–
|
|
KEGG:
R09044
|
|
|
|
primary_fluorescent_chlorophyll_catabolite + oxidized_ferredoxin <=> red_chlorophyll_catabolite + reduced_ferredoxin_[iron-sulfur]_cluster + H+
|
1.3.7.12
red chlorophyll catabolite reductase
|
–
|
|
BRENDA:
BR48852
KEGG:
R09032
MetaCyc:
RXN-7741
|
|
|
|
geranyl_diphosphate <=> citral
|
not assigned
|
–
|
|
KEGG:
R08398
|
|
|
|
19-Chloroproansamitocin <=> 20-O-Methyl-19-chloroproansamitocin
|
not assigned
|
–
|
|
KEGG:
R09852
|
|
|
|
acyl-CoA + 2-acyl-sn-glycerol_3-phosphate <=> phosphatidic_acid + CoA
|
2.3.1.52
2-acylglycerol-3-phosphate O-acyltransferase
|
–
|
|
BRENDA:
BR44054
KEGG:
R02242
MetaCyc:
2-ACYL2.3.1.15-RXN
|
|
|
|
1alpha(S)-6-O-methyl-N-deacetylisoipecoside_aglycone <=> Protoemetine
|
not assigned
|
–
|
|
KEGG:
R11683
|
|
|
|
UDP-glucose + betanidin <=> H+ + betanin + UDP
|
2.4.1
|
–
|
|
KEGG:
R08822
MetaCyc:
RXN-8479
|
|
|
|
6''-Oxogentamicin_X2 + L-glutamate <=> JI-20A + 2-oxoglutarate
|
2.6.1
|
–
|
|
KEGG:
R11297
|
|
|
|
(+)-bornyl-diphosphate + H2O <=> (+)-borneol + diphosphate
|
3.1.3
3.1.7.3
monoterpenyl-diphosphatase
|
–
–
|
|
KEGG:
R08529
MetaCyc:
RXN-13046
|
|
|
|
(+)-epi-isozizaene + O2 + NADPH + H+ <=> (5S)-albaflavenol + H2O + NADP+
|
1.14.13.106
epi-isozizaene 5-monooxygenase
|
–
|
|
BRENDA:
BR48977
KEGG:
R08851
MetaCyc:
RXN-9350
|
|
|
|
acetyl-CoA + serotonin <=> H+ + CoA + N-acetylserotonin
|
2.3.1.5
arylamine N-acetyltransferase
2.3.1.87
aralkylamine N-acetyltransferase
|
–
–
|
|
BRENDA:
BS320965
KEGG:
R02911
MetaCyc:
RXN3DJ-35528
SABIO-RK:
2771
|
|
|
|
S-adenosyl-L-methionine + 5-hydroxyferuloyl-CoA <=> H+ + S-adenosyl-L-homocysteine + sinapoyl-CoA
|
2.1.1.104
caffeoyl-CoA O-methyltransferase
|
–
|
|
BRENDA:
BS407330
KEGG:
R06578
MetaCyc:
RXN-1123
|
|
|
|
S-adenosyl-L-methionine + 6-geranylgeranyl-2-methylbenzene-1,4-diol <=> S-adenosyl-L-homocysteine + 6-geranylgeranyl-2,3-dimethylbenzene-1,4-diol + H+
|
2.1.1.295
2-methyl-6-phytyl-1,4-hydroquinone methyltransferase
|
–
|
|
BRENDA:
BR50941
KEGG:
R10710
MetaCyc:
RXN-14917
|
|
|
|
(S)-2-hydroxy-2-ethyl-3-oxobutanoate <=> (R)-3-hydroxy-3-methyl-2-oxopentanoate
|
1.1.1.86
ketol-acid reductoisomerase (NADP+)
5.4.99.3
2-acetolactate mutase
|
–
–
|
|
KEGG:
R05069
MetaCyc:
RXN-14106
|
|
|
|
(S)-2-amino-6-oxohexanoate + NAD+ + H2O <=> L-2-aminoadipate + NADH + H+
|
1.2.1.31
L-aminoadipate-semialdehyde dehydrogenase
|
–
|
|
BRENDA:
BR29399-a
KEGG:
R03102
MetaCyc:
1.2.1.31-RXN_WOP;
ALLYSINE-DEHYDROG-RXN
SABIO-RK:
6517
|
|
|
|
20-oxo-5-O-beta-mycaminosyltylactone + O2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> 5-O-beta-mycaminosyltylonolide + H2O + oxidized_ferredoxin
|
1.14.15.34
20-oxo-5-O-mycaminosyltylactone 23-monooxygenase
|
–
|
|
BRENDA:
BR50923
KEGG:
R10656
MetaCyc:
RXN-15060
|
|
|
|
S-adenosyl-L-methionine + Coproporphyrinogen-III <=> protoporphyrinogen-IX + CO2 + L-methionine + 5''-deoxyadenosine
|
1.3.98.3
coproporphyrinogen dehydrogenase
|
–
|
|
BRENDA:
BR48612
KEGG:
R06895
MetaCyc:
HEMN-RXN
|
|
|
|
9beta-pimara-7,15-dien-19-oate <=> 3beta-hydroxy-9beta-pimara-7,15-diene-19,6beta-olide
|
not assigned
|
–
|
|
KEGG:
R09118
MetaCyc:
RXN-15399
|
|
|
|
chanoclavine-I_aldehyde <=> 6,8-dimethyl-6,7,8,9-tetradehydroergoline + H2O
|
not assigned
|
–
|
|
KEGG:
R12094
MetaCyc:
RXN-13469
|
|
|
|
Isobutyronitrile + reduced_flavodoxin + O2 <=> acetone_cyanohydrin + flavin + H2O
|
1.14.14.41
(E)-2-methylbutanal oxime monooxygenase
|
–
|
|
BRENDA:
BR51946
KEGG:
R11642
|
|
|
|
(-)-alpha-terpineol <=> 1,8-cineole
|
4.2.3.108
1,8-cineole synthase
|
–
|
|
KEGG:
R06422
|
|
|
|
Coproporphyrinogen-III + O2 <=> coproporphyrin_III + H2O2
|
1.3.3.15
coproporphyrinogen III oxidase (coproporphyrin-forming)
1.3.3.4
protoporphyrinogen oxidase
|
–
–
|
|
BRENDA:
BR51650
KEGG:
R04178
MetaCyc:
RXN-17517
SABIO-RK:
13675
|
|
|
|
(R)-reticuline + NADP+ <=> 1,2-dehydroreticuline + NADPH + H+
|
1.5.1.27
1,2-dehydroreticulinium reductase (NADPH)
|
–
|
|
BRENDA:
BR1298
KEGG:
R04695
MetaCyc:
1.5.1.27-RXN
|
|
|
|
(S)-malate <=> fumarate + H2O
|
4.2.1.2
fumarate hydratase
4.2.1.34
(S)-2-methylmalate dehydratase
|
–
–
|
|
BRENDA:
BR3389
KEGG:
R01082
MetaCyc:
FUMHYDR-RXN
SABIO-RK:
256
|
|
|
|
(-)-bursehernin + reduced_flavodoxin + O2 <=> (-)-5''-demethylyatein + flavin + H2O
|
1.14.14.131
bursehernin 5'-monooxygenase
|
–
|
|
BRENDA:
BR51573
KEGG:
R11211
|
|
|
|
Zymosterol + NADPH <=> 5alpha-cholesta-8-en-3beta-ol + NADP+
|
1.3.1.72
Delta24-sterol reductase
|
–
|
|
BRENDA:
BS189400
KEGG:
R07498
|
|
|
|
S-adenosyl-L-methionine + dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose <=> S-adenosyl-L-homocysteine + TDP-3-dimethylamino-4,6-dideoxy-alpha-D-glucopyranose + H+
|
2.1.1.234
dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase
2.1.1.235
dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase
|
–
–
|
|
BRENDA:
BR49870
KEGG:
R06427
MetaCyc:
RXN-12767
|
|
|
|
2-Undecylpyrrole + NAD+ + H2O <=> 4-Keto-2-undecylpyrroline + NADH + H+
|
1.17.1
|
–
|
|
KEGG:
R11666
MetaCyc:
RXN1A0-6098_WOP
|
|
|
|
theophylline + NADPH + O2 + H+ <=> 3-Methylxanthine + NADP+ + formaldehyde + H2O
|
1.14.13.178
methylxanthine N1-demethylase
|
–
|
|
BRENDA:
BR50578
KEGG:
R07974
MetaCyc:
RXN-13108
|
|
|
|
octanoyl-CoA + L-Cysteinyl-protein <=> S-Octanoyl-L-cysteinyl-protein + CoA
|
2.3.1.230
2-heptyl-4(1H)-quinolone synthase
|
–
|
|
KEGG:
R10590
|
|
|
|
D-ribulose_5-phosphate <=> D-xylulose_5-phosphate
|
5.1.3.1
ribulose-phosphate 3-epimerase
5.3.1.34
D-erythrulose 4-phosphate isomerase
|
–
–
|
|
BRENDA:
BR184
KEGG:
R01529
MetaCyc:
RIBULP3EPIM-RXN
SABIO-RK:
62
|
|
|
|
acyl_phosphate + sn-glycerol_3-phosphate <=> lysophosphatidic_acid + phosphate
|
2.3.1.275
acyl phosphate:glycerol-3-phosphate acyltransferase
|
–
|
|
BRENDA:
BR52534
KEGG:
R12241
MetaCyc:
RXN-9591
|
|
|
|
24(28)-methylene_lophenol + O2 + ferricytochrome_b5 + H+ <=> 3beta-hydroxyergosta-7,24(241)-dien-4alpha-carboxylate + ferricytochrome_b5 + H2O
|
1.14.18.11
plant 4alpha-monomethylsterol monooxygenase
|
–
|
|
BRENDA:
BR52727
KEGG:
R12378
MetaCyc:
RXN-19724
|
|
|
|
2-oxoadipate + NAD+ + CoA <=> CO2 + NADH + glutaryl-CoA
|
1.2.1.ak
1.2.4.2
oxoglutarate dehydrogenase (succinyl-transferring)
1.8.1.4
dihydrolipoyl dehydrogenase
2.3.1.61
dihydrolipoyllysine-residue succinyltransferase
|
–
–
–
–
|
|
KEGG:
R01933
MetaCyc:
2-KETO-ADIPATE-DEHYDROG-RXN
SABIO-RK:
1987
|
|
|
|
O2 + linolenic_acid <=> (9Z,11E,13S,15Z)-13-hydroperoxy-9,11,15-octadecatrienoate
|
1.13.11.12
linoleate 13S-lipoxygenase
1.13.11.45
linoleate 11-lipoxygenase
|
–
–
|
|
BRENDA:
BR50226;
BS186660
KEGG:
R07869
MetaCyc:
RXN-1321
SABIO-RK:
9850
|
|
|
|
NDP-1-epi-valienol + 2-Amino-1,5-anhydro-2-deoxyglucitol <=> Salbostatin_6''-phosphate + NDP
|
2.5.1.135
validamine 7-phosphate valienyltransferase
|
–
|
|
KEGG:
R11250
|
|
|
|
(2E,6E)-farnesyl_diphosphate + n isopentenyl_diphosphate <=> n diphosphate + di-trans,poly-cis-polyprenyl_diphosphate
|
2.5.1.87
ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific]
2.5.1.88
trans,polycis-polyprenyl diphosphate synthase [(2Z,6E)-farnesyl diphosphate specific]
|
–
–
|
|
BRENDA:
BS406958;
BS407552;
BS436200
KEGG:
R05556
|
|
|
|
UDP-glucose + beta-D-glucosyl_crocetin <=> bis(beta-D-glucosyl)_crocetin + UDP
|
2.4.1.271
crocetin glucosyltransferase
|
–
|
|
BRENDA:
BR49757
KEGG:
R09758
MetaCyc:
RXN-8473
|
|
|
|
prephenate + NADP+ <=> 4-hydroxyphenylpyruvate + CO2 + NADPH
|
1.3.1.12
prephenate dehydrogenase
1.3.1.13
prephenate dehydrogenase (NADP+)
1.3.1.78
arogenate dehydrogenase (NADP+)
1.3.1.79
arogenate dehydrogenase [NAD(P)+]
|
–
–
–
–
|
|
BRENDA:
BR36798
KEGG:
R01730
MetaCyc:
PREPHENATE-DEHYDROGENASE-NADP+-RXN
SABIO-RK:
1840
|
|
|
|
1-deoxy-11-oxopentalenate + O2 + NADPH + H+ <=> pentalenolactone_D + H2O + NADP+
|
1.14.13.170
pentalenolactone D synthase
|
–
|
|
BRENDA:
BR50265
KEGG:
R10154
MetaCyc:
RXN-12654
|
|
|
|
UDP-glucose + 2-(3-indolyl)acetothiohydroximate <=> desulfo-indol-3-yl-methyl_glucosinolate + UDP
|
2.4.1.195
N-hydroxythioamide S-beta-glucosyltransferase
|
–
|
|
BRENDA:
BR52366
KEGG:
R08164
MetaCyc:
RXN-1442
|
|
|
|
zeinoxanthin + reduced_flavodoxin + O2 <=> lutein + flavin + H2O
|
1.14.14.158
carotenoid epsilon hydroxylase
|
–
|
|
BRENDA:
BR52468
KEGG:
R07531
|
|
|
|
C20911 <=> C20912
|
not assigned
|
–
|
|
KEGG:
R10885
|
|
|
|
menaquinone + NADH + H+ <=> menaquinol + NAD+
|
1.6.5
1.6.5.2
NAD(P)H dehydrogenase (quinone)
1.6.5.9
NADH:quinone reductase (non-electrogenic)
7.1.1.2
NADH:ubiquinone reductase (H+-translocating)
7.2.1.1
NADH:ubiquinone reductase (Na+-transporting)
|
–
–
–
–
–
|
|
BRENDA:
BS260199-a;
BS389339
KEGG:
R02964
MetaCyc:
RXN-20991;
RXN0-5388;
RXN0-7123
|
|
|
|
(1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate <=> (1R)-1,4,5,10-tetrahydrophenazine-1-carboxylate
|
not assigned
|
–
|
|
KEGG:
R11571
MetaCyc:
RXN-17692
|
|
|
|
dTDP-6-deoxy-alpha-D-allose + Mycinamicin_VII <=> mycinamicin_VI + dTDP + H+
|
2.4.1
|
–
|
|
KEGG:
R10874
MetaCyc:
RXN-15052
|
|
|
|
(+)-cis-isopulegone + NADP+ <=> (-)-isopiperitenone + NADPH + H+
|
1.3.1.82
(-)-isopiperitenone reductase
|
–
|
|
BRENDA:
BR48928
KEGG:
R06417
MetaCyc:
RXN-5161
|
|
|
|
5-amino-1-(5-phospho-D-ribosyl)imidazole + ATP + HCO3- <=> H+ + 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + phosphate
|
6.3.4.18
5-(carboxyamino)imidazole ribonucleotide synthase
|
–
|
|
BRENDA:
BR48708
KEGG:
R07404
MetaCyc:
RXN0-742
|
|
|
|
(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA <=> tigloyl-CoA + H2O
|
4.2.1.17
enoyl-CoA hydratase
|
–
|
|
BRENDA:
BS444413
KEGG:
R04204
MetaCyc:
TIGLYLCOA-HYDROXY-RXN
SABIO-RK:
3920
|
|
|
|
dTDP-6-deoxy-alpha-D-allose + NADP+ <=> dTDP-4-dehydro-6-deoxy-alpha-D-gulose + NADPH + H+
|
1.1.1.364
dTDP-4-dehydro-6-deoxy-alpha-D-gulose 4-ketoreductase
|
–
|
|
BRENDA:
BR50819
KEGG:
R10573
MetaCyc:
RXN-15048
|
|
|
|
Roquefortine_F + reduced_flavodoxin + O2 <=> Neoxaline + flavin + H2O
|
1.14.14
|
–
|
|
KEGG:
R12448
|
|
|
|
5alpha-Cholest-7-en-3beta-ol + ferricytochrome_b5 + O2 + H+ <=> 7-dehydrocholesterol + ferricytochrome_b5 + H2O
|
1.14.19.20
Delta7-sterol 5(6)-desaturase
|
–
|
|
BRENDA:
BS258666;
BS432737
KEGG:
R07215
MetaCyc:
1.14.21.6-RXN
SABIO-RK:
14442
|
|
|
|
Fumiquinazoline_C <=> Fumiquinazoline_D
|
not assigned
|
–
|
|
KEGG:
R12421
MetaCyc:
RXN-15750
|
|
|
|
N-Acetyl-N6,N6,O-tridemethylpuromycin-5''-phosphate + S-adenosyl-L-methionine <=> N-Acetyl-N6,O-didemethylpuromycin-5''-phosphate + S-adenosyl-L-homocysteine
|
2
|
–
|
|
KEGG:
R05673
|
|
|
|
copalyl_diphosphate + H2O <=> aphidicolan-16beta-ol + diphosphate
|
4.2.3.42
aphidicolan-16beta-ol synthase
|
–
|
|
BRENDA:
BR49049
KEGG:
R06313
|
|
|
|
demethyllactenocin + dTDP-beta-L-mycarose <=> Demethylmacrocin + dTDP + H+
|
2.4.1.318
demethyllactenocin mycarosyltransferase
|
–
|
|
BRENDA:
BR50951
KEGG:
R06452
MetaCyc:
RXN-15058
|
|
|
|
Ajmalicine + reduced_flavodoxin + O2 <=> serpentine + flavin + 2 H2O + 2 H+
|
1.14.14
|
–
|
|
KEGG:
R05849
|
|
|
|
dimethylallyl_diphosphate + Paspalinine <=> Aflatrem + diphosphate
|
2.5.1
|
–
|
|
KEGG:
R10365
MetaCyc:
RXN-15739
|
|
|
|
ergosterol + light <=> vitamin_D2
|
not assigned
|
–
|
|
KEGG:
R03677
|
|
|
|
(S)-2-methylbutanoyl-CoA + acceptor <=> tigloyl-CoA + reduced_acceptor
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
1.3.8.7
medium-chain acyl-CoA dehydrogenase
1.3.99.12
2-methylacyl-CoA dehydrogenase
|
–
–
–
|
|
BRENDA:
BS258775
KEGG:
R03172
|
|
|
|
geranyl_diphosphate + isopentenyl_diphosphate <=> diphosphate + (2Z,6E)-farnesyl_diphosphate
|
2.5.1.68
(2Z,6E)-farnesyl diphosphate synthase
|
–
|
|
BRENDA:
BR48805
KEGG:
R08528
MetaCyc:
2.5.1.68-RXN
|
|
|
|
Palustradienol <=> Palustradienal
|
1.14.13
|
–
|
|
KEGG:
R09109
|
|
|
|
ferruginol + 2 reduced_flavodoxin + 2 O2 <=> sugiol + 2 flavin + 3 H2O
|
1.14.14.65
sugiol synthase
|
–
|
|
BRENDA:
BR52297
KEGG:
R11977
|
|
|
|
N3-fumarylcarboxyamido-L-2,3-diaminopropionic_acid + L-isoleucine + ATP <=> 3-{[(2E)-4-amino-4-oxobut-2-enoyl]amino}-L-alanyl-L-isoleucine + ADP + phosphate + H+
|
6.3.2.47
dapdiamide synthase
|
–
|
|
BRENDA:
BR51331
KEGG:
R10943
MetaCyc:
RXN-16292
|
|
|
|
acetyl-CoA + (13S,14R)-1,13-dihydroxy-N-methylcanadine <=> (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine + CoA
|
2.3.1.285
(13S,14R)-1,13-dihydroxy-N-methylcanadine 13-O-acetyltransferase
|
–
|
|
BRENDA:
BR52689
KEGG:
R11689
MetaCyc:
RXN-19905
|
|
|
|
phosphate + trehalose <=> beta-D-glucose_1-phosphate + D-glucose
|
2.4.1.64
alpha,alpha-trehalose phosphorylase
|
–
|
|
BRENDA:
BR44241;
BS399948
KEGG:
R02727;
R06053
MetaCyc:
ALPHAALPHA-TREHALOSE-PHOSPHORYLASE-RXN
|
|
|
|
13-deoxydaunorubicin + NADPH + H+ + O2 <=> 13-dihydrodaunorubicin + NADP+ + H2O
|
1.14.13.181
13-deoxydaunorubicin hydroxylase
|
–
|
|
BRENDA:
BR50584
KEGG:
R06688
MetaCyc:
RXN-14829
|
|
|
|
fumitremorgin_B + 2-oxoglutarate + 2 O2 + reduced_acceptor <=> verruculogen + succinate + CO2 + H2O + acceptor
|
1.14.11.38
verruculogen synthase
|
–
|
|
BRENDA:
BR50568;
BS421968
KEGG:
R10445
|
|
|
|
cis-geranyl-CoA + HCO3- + ATP <=> 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + phosphate + ADP + H+
|
6.4.1.5
geranoyl-CoA carboxylase
|
–
|
|
BRENDA:
BR157
KEGG:
R03494
MetaCyc:
GERANOYL-COA-CARBOXYLASE-RXN
|
|
|
|
2-exo-hydroxy-1,8-cineole + NAD+ <=> 6-Oxocineole + NADH + H+
|
1.1.1.241
6-endo-hydroxycineole dehydrogenase
|
–
|
|
BRENDA:
BR29278
KEGG:
R02994
MetaCyc:
6-ENDO-HYDROXYCINEOLE-DEHYDROGENASE-RXN
|
|
|
|
8-O-methyldihydrosterigmatocystin + 2 reduced_flavodoxin + 2 O2 <=> Aflatoxin_B2 + 2 flavin + H2O + methanol + CO2
|
1.14.14.117
aflatoxin B synthase
|
–
|
|
BRENDA:
BR50524
KEGG:
R10320
|
|
|
|
4-methylthiobutanaldoxime + L-cysteine + reduced_flavodoxin + O2 <=> S-(4-Methylthiobutylthiohydroximoyl)-L-cysteine + flavin + 2 H2O
|
1.14.14.43
(methylsulfanyl)alkanaldoxime N-monooxygenase
|
–
|
|
KEGG:
R08666
|
|
|
|
S-adenosyl-L-methionine + dTDP-4-amino-2,4-dideoxy-beta-L-xylose <=> S-adenosyl-L-homocysteine + dTDP-4-methylamino-2,4-dideoxy-beta-L-xylose
|
2.1.1
|
–
|
|
KEGG:
R11476
|
|
|
|
kanamycin_X + O2 <=> 6''-Oxokanamycin_X + H2O2
|
1.1.3
|
–
|
|
KEGG:
R11267
|
|
|
|
protoporphyrinogen-IX + 3 1,4-benzoquinone <=> protoporphyrin_IX + 3 hydroquinone
|
1.3.5.3
protoporphyrinogen IX dehydrogenase (quinone)
|
–
|
|
BRENDA:
BR49166
KEGG:
R09489
|
|
|
|
gibberellin_A12 <=> Gibberellin_A14
|
not assigned
|
–
|
|
KEGG:
R06333
|
|
|
|
valienone_7-phosphate <=> 1-epi-valienol_7-phosphate
|
not assigned
|
–
|
|
KEGG:
R11235
|
|
|
|
Dihydrokalafungin_dihydroquinone_form + O2 + FMNH2 <=> 1,3,6,8-Tetrahydroxynaphthalene + H2O + FMN + H+
|
1.14.14
|
–
|
|
KEGG:
R09313
MetaCyc:
RXN-18115
|
|
|
|
2,3-Epoxymenaquinone + dithiothreitol <=> menaquinone + oxidized_dithiothreitol + H2O
|
1.17.4.4
vitamin-K-epoxide reductase (warfarin-sensitive)
|
–
|
|
KEGG:
R09992
|
|
|
|
campesterol + NADPH + H+ + O2 <=> 6-deoxocathasterone + NADP+ + H2O
|
1.14.13
1.14.99.B1
|
–
–
|
|
BRENDA:
BS396649
KEGG:
R07454
SABIO-RK:
12699
|
|
|
|
S-adenosyl-L-methionine + erythromycin_C <=> S-adenosyl-L-homocysteine + erythromycin + H+
|
2.1.1.254
erythromycin 3''-O-methyltransferase
|
–
|
|
BRENDA:
BR49887
KEGG:
R05520
MetaCyc:
RXN-12923
|
|
|
|
geranyl_diphosphate + isopentenyl_diphosphate <=> (2E,6E)-farnesyl_diphosphate + diphosphate
|
2.5.1.1
dimethylallyltranstransferase
2.5.1.10
(2E,6E)-farnesyl diphosphate synthase
2.5.1.29
geranylgeranyl diphosphate synthase
|
–
–
–
|
|
BRENDA:
BR47562
KEGG:
R02003
MetaCyc:
FPPSYN-RXN
SABIO-RK:
2041
|
|
|
|
Mycinamicin_V + O2 + NADPH + H+ <=> mycinamicin_II + H2O + NADP+
|
1.14.13
|
–
|
|
KEGG:
R10878
MetaCyc:
RXN-15050
|
|
|
|
theophylline + NADH + O2 + H+ <=> 3-Methylxanthine + NAD+ + formaldehyde + H2O
|
1.14.13.128
7-methylxanthine demethylase
1.14.13.178
methylxanthine N1-demethylase
|
–
–
|
|
BRENDA:
BR50578-a
KEGG:
R07973
MetaCyc:
RXN-13108_WOP
|
|
|
|
9,15,9''-tri-cis-zeta-carotene <=> 9,9''-di-cis-zeta-carotene
|
5.2.1.12
zeta-carotene isomerase
|
–
|
|
BRENDA:
BR49728
KEGG:
R09655
MetaCyc:
RXN-11354
|
|
|
|
GDP-valienol + validamine_7-phosphate <=> validoxylamine_A_7''-phosphate + GDP + H+
|
2.5.1.135
validamine 7-phosphate valienyltransferase
|
–
|
|
BRENDA:
BR51891
KEGG:
R11497
MetaCyc:
RXN-17379
|
|
|
|
ATP + 2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate + 2-oxoglutarate <=> AMP + diphosphate + 5-[(2-{[(3S)-5-{[(2S)-2-amino-2-carboxyethyl]amino}-3-carboxy-3-hydroxy-5-oxopentanoyl]amino}ethyl)amino]-2,5-dioxopentanoate + H+
|
6.3.2.55
2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate synthase
6.3.2.56
staphyloferrin B synthase
|
–
–
|
|
BRENDA:
BR52707
KEGG:
R12312
MetaCyc:
RXN-19823
|
|
|
|
geranylgeranyl_diphosphate + homogentisate + H+ <=> diphosphate + 6-geranylgeranyl-2-methylbenzene-1,4-diol + CO2
|
2.5.1.115
homogentisate phytyltransferase
2.5.1.116
homogentisate geranylgeranyltransferase
|
–
–
|
|
BRENDA:
BR50959
KEGG:
R10708
MetaCyc:
RXN-14929
|
|
|
|
protopine + reduced_flavodoxin + O2 <=> 6-hydroxyprotopine + flavin + H2O
|
1.14.14.98
protopine 6-monooxygenase
|
–
|
|
BRENDA:
BR652
KEGG:
R04699
|
|
|
|
dTDP-4-amino-4,6-dideoxy-alpha-D-glucopyranose + reduced_ferredoxin + O2 <=> dTDP-4-hydroxyamino-4,6-dideoxy-alpha-D-glucose + oxidized_ferredoxin + H2O
|
1.14.15
|
–
|
|
KEGG:
R11468
|
|
|
|
1-deoxy-D-threo-hexo-2,5-diulose_6-phosphate + L-aspartate_4-semialdehyde <=> 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + 2,3-dioxopropyl_phosphate
|
2.2.1.10
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase
|
–
|
|
BRENDA:
BR50116
KEGG:
R08568
MetaCyc:
RXN-10031
|
|
|
|
NDP-4-oxo-6-deoxy-D-mannose <=> NDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose
|
not assigned
|
–
|
|
KEGG:
R11431
|
|
|
|
versicolorone + NADP+ <=> 1'-hydroxyversicolorone + NADPH
|
1.1.1.353
versiconal hemiacetal acetate reductase
|
–
|
|
BRENDA:
BR50504
KEGG:
R09756
MetaCyc:
RXN-9489
|
|
|
|
19-Hydroxytabersonine <=> Horhammericine
|
not assigned
|
–
|
|
KEGG:
R05871
|
|
|
|
7,12-Decaketide_intermediate_1 <=> Decaketide_tricyclic_intermediate
|
not assigned
|
–
|
|
KEGG:
R09350
|
|
|
|
(5R)-albaflavenol + O2 + NADPH + H+ <=> albaflavenone + H2O + NADP+
|
1.14.13.106
epi-isozizaene 5-monooxygenase
|
–
|
|
BRENDA:
BR48980
KEGG:
R08854
MetaCyc:
RXN-9353
|
|
|
|
(S)-4-Amino-5-oxopentanoate + NADP+ + tRNAMet <=> Glu-tRNAGln + NADPH + H+
|
1.2.1.70
glutamyl-tRNA reductase
|
–
|
|
BRENDA:
BR48497
KEGG:
R04109
SABIO-RK:
9145
|
|
|
|
2-[(2''-methylsulfanyl)ethyl]malate <=> 3-[(2''-methylsulfanyl)ethyl]malate
|
4.2.1.170
2-(omega-methylthio)alkylmalate dehydratase
|
–
|
|
KEGG:
R08620
MetaCyc:
RXN-2203
|
|
|
|
N1,N5,N10-Tricoumaroyl_spermidine <=> N1,N5,N10-Tricaffeoyl_spermidine
|
1.14.13
|
–
|
|
KEGG:
R08984
|
|
|
|
kanosamine_6-phosphate + 2-oxoglutarate <=> 3-dehydro-D-glucose_6-phosphate + L-glutamate
|
2.6.1.104
3-dehydro-glucose-6-phosphate---glutamate transaminase
|
–
|
|
BRENDA:
BR50964
KEGG:
R10698
MetaCyc:
RXN8J2-137
|
|
|
|
putrescine <=> Homospermidine + NH3
|
2.5.1.44
homospermidine synthase
|
–
|
|
BRENDA:
BR29481
KEGG:
R00018
MetaCyc:
2.5.1.44-RXN
|
|
|
|
(R)-3-(4-hydroxyphenyl)lactate + NADP+ <=> 4-hydroxyphenylpyruvate + NADPH + H+
|
1.1.1.110
aromatic 2-oxoacid reductase
1.1.1.237
hydroxyphenylpyruvate reductase
|
–
–
|
|
BRENDA:
BR29263;
BS370805
KEGG:
R03339
MetaCyc:
1.1.1.222-RXN
|
|
|
|
acarbose_7'''-phosphate <=> acarbose
|
not assigned
|
–
|
|
KEGG:
R11305
|
|
|
|
(1''S)-averantin + reduced_flavodoxin + O2 <=> (1''S,5''S)-5''-hydroxyaverantin + flavin + H2O
|
1.14.14.116
averantin hydroxylase
|
–
|
|
BRENDA:
BR50521
KEGG:
R10317
|
|
|
|
Avermectin_A1a_aglycone + dTDP-L-oleandrose <=> Avermectin_A1a_monosaccharide + dTDP
|
2.4.1
|
–
|
|
KEGG:
R06490
|
|
|
|
NADP+ + 3-oxo-2((2Z)-pentenyl)-cyclopentane-1-octanoic_acid <=> H+ + NADPH + 12-oxo-phytodienoic_acid
|
1.3.1.42
12-oxophytodienoate reductase
|
–
|
|
BRENDA:
BR36824
KEGG:
R03401
MetaCyc:
12-OXOPHYTODIENOATE-REDUCTASE-RXN
|
|
|
|
15,16-dihydrobiliverdin + oxidized_ferredoxin <=> Biliverdin + reduced_ferredoxin_[iron-sulfur]_cluster + H+
|
1.3.7.2
15,16-dihydrobiliverdin:ferredoxin oxidoreductase
1.3.7.6
phycoerythrobilin synthase
|
–
–
|
|
BRENDA:
BR40359
KEGG:
R05818
MetaCyc:
1.3.7.2-RXN
|
|
|
|
S-adenosyl-L-methionine + (S)-scoulerine <=> H+ + S-adenosyl-L-homocysteine + (S)-tetrahydrocolumbamine
|
2.1.1.117
(S)-scoulerine 9-O-methyltransferase
|
–
|
|
BRENDA:
BR1438
KEGG:
R03835
MetaCyc:
2.1.1.117-RXN
SABIO-RK:
3591
|
|
|
|
(E)-phenylacetaldoxime <=> (Z)-phenylacetaldoxime
|
1.14.14.44
phenylacetaldehyde oxime monooxygenase
|
–
|
|
BRENDA:
BR52033
KEGG:
R10041
MetaCyc:
RXN-12065
|
|
|
|
paromamine + UDP-alpha-D-kanosamine <=> kanamycin_C + UDP + H+
|
2.4.1.301
2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase
|
–
|
|
BRENDA:
BR50649
KEGG:
R10426
MetaCyc:
RXN-13145
|
|
|
|
24-methylene_cholesterol + NADPH + H+ <=> ergosta-5-enol + NADP+
|
1.3.1
|
–
|
|
KEGG:
R11096
|
|
|
|
laurate + malonyl-CoA + glycine <=> 4-Keto-2-undecylpyrroline + 2 H2O + 2 CO2 + CoA
|
not assigned
|
–
|
|
KEGG:
R11664
|
|
|
|
H+ + L-aspartate <=> beta-Alanine + CO2
|
4.1.1.11
aspartate 1-decarboxylase
4.1.1.15
glutamate decarboxylase
4.1.1.25
tyrosine decarboxylase
4.1.1.29
sulfinoalanine decarboxylase
|
–
–
–
–
|
|
BRENDA:
BR272
KEGG:
R00489
MetaCyc:
ASPDECARBOX-RXN
SABIO-RK:
921
|
|
|
|
3-dehydroquinate <=> H2O + 3-dehydroshikimate
|
4.2.1.10
3-dehydroquinate dehydratase
|
–
|
|
BRENDA:
BR401
KEGG:
R03084
MetaCyc:
3-DEHYDROQUINATE-DEHYDRATASE-RXN
SABIO-RK:
2924
|
|
|
|
4-coumaroyl-CoA <=> caffeoyl-CoA
|
1.14.13
|
–
|
|
KEGG:
R07436
|
|
|
|
isocitrate <=> glyoxylate + succinate
|
4.1.3.1
isocitrate lyase
|
–
|
|
BRENDA:
BR3364;
BS380792
KEGG:
R00479
MetaCyc:
ISOCIT-CLEAV-RXN
SABIO-RK:
14841
|
|
|
|
3-oxo-2((2Z)-pentenyl)-cyclopentane-1-octanoic_acid + CoA + ATP <=> 3-oxo-2-(cis-2''-pentenyl)-cyclopentane-1-octanoyl-CoA + AMP + diphosphate
|
6.2.1
|
–
|
|
KEGG:
R07887
MetaCyc:
RXN-10695
|
|
|
|
3-(hydroxyphosphonoylmethyl)malate <=> Deamino-alpha-keto-demethylphosphinothricin
|
not assigned
|
–
|
|
KEGG:
R08888
|
|
|
|
H2O + N-acetyl-L,L-2,6-diaminopimelate <=> LL-2,6-Diaminoheptanedioate + acetate
|
3.5.1.47
N-acetyldiaminopimelate deacetylase
|
–
|
|
BRENDA:
BR19248;
BS116335
KEGG:
R02733
MetaCyc:
N-ACETYLDIAMINOPIMELATE-DEACETYLASE-RXN
|
|
|
|
Dihydrokalafungin + NADH + H+ <=> Dihydrokalafungin_dihydroquinone_form + NAD+
|
not assigned
|
–
|
|
KEGG:
R09312
|
|
|
|
ascorbate + 1-aminocyclopropane-1-carboxylate + O2 <=> H2O + ethylene + dehydroascorbate + cyanide + CO2
|
1.14.17.4
aminocyclopropanecarboxylate oxidase
|
–
|
|
BRENDA:
BR47609
KEGG:
R07214
MetaCyc:
ETHYL-RXN
SABIO-RK:
7762
|
|
|
|
malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> 10-deoxymethynolide + CoA + CO2 + H2O + NADP+
|
2.3.1.239
10-deoxymethynolide synthase
|
–
|
|
BRENDA:
BR51189
KEGG:
R06458
MetaCyc:
RXN-15103
|
|
|
|
isochorismate <=> salicylate + pyruvate
|
3.3.2.1
isochorismatase
4.2.99.21
isochorismate lyase
|
–
–
|
|
BRENDA:
BR49395
KEGG:
R06602
MetaCyc:
RXN-1981
SABIO-RK:
6177
|
|
|
|
trehalose + H2O <=> D-glucose + D-glucose
|
3.2.1.10
oligo-1,6-glucosidase
3.2.1.20
alpha-glucosidase
3.2.1.28
alpha,alpha-trehalase
3.2.1.3
glucan 1,4-alpha-glucosidase
|
–
–
–
–
|
|
BRENDA:
BR15991;
BS259712;
BS370856;
BS372300
KEGG:
R00010;
R06103
MetaCyc:
TREHALA-RXN
SABIO-RK:
11797;
6476
|
|
|
|
(10bS,4aR)-noroxomaritidine <=> (4aR,10bS)-Normaritidine
|
not assigned
|
–
|
|
KEGG:
R11754
|
|
|
|
4-hydroxy-2,2''-bipyrrole-5-methanol + NADP+ <=> 4-hydroxy-2,2''-bipyrrole-5-carbaldehyde + NADPH + H+
|
1.1.1
|
–
|
|
KEGG:
R11668
MetaCyc:
RXN-15785
|
|
|
|
ATP + fumarate + L-2,3-diaminopropionic_acid <=> AMP + diphosphate + N3-fumaroyl-L-2,3-diaminopropanoic_acid + H+
|
6.3.2.46
fumarate---(S)-2,3-diaminopropanoate ligase
|
–
|
|
BRENDA:
BR51256
KEGG:
R10940
MetaCyc:
RXN-16290
|
|
|
|
ATP + 2-(formamido)-N1-(5-phosphoribosyl)acetamidine <=> H+ + ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole
|
6.3.3.1
phosphoribosylformylglycinamidine cyclo-ligase
|
–
|
|
BRENDA:
BR126
KEGG:
R04208
MetaCyc:
AIRS-RXN
|
|
|
|
Avermectin_B1b_monosaccharide + dTDP-L-oleandrose <=> avermectin_B1b + dTDP
|
2.4.1
|
–
|
|
KEGG:
R06497
|
|
|
|
starch <=> Dextrin + maltose
|
3.2.1.1
alpha-amylase
3.2.1.133
glucan 1,4-alpha-maltohydrolase
3.2.1.2
beta-amylase
|
–
–
–
|
|
KEGG:
R02112
|
|
|
|
1,6,6-Trimethyl-2,7-dioxa(3,2,2)bicyclononan-3-one <=> 4,5-Dihydro-5,5-dimethyl-4-(3-oxobutyl)furan-2(3H)-one
|
not assigned
|
–
|
|
KEGG:
R04578
MetaCyc:
C04718-C060066-AUTOTRANSFORMATION-RXN
|
|
|
|
UDP-glucose + 2-Methyl-2-hydroxybutyronitrile <=> lotaustralin + UDP + H+
|
2.4.1.63
linamarin synthase
|
–
|
|
KEGG:
R10037
MetaCyc:
RXN-9643
|
|
|
|
Chromopyrrolate + O2 + NADH + H+ <=> staurosporine_aglycone + CO2 + H2O + NAD+
|
1.13.12
|
–
|
|
KEGG:
R11121
MetaCyc:
RXN-10924
|
|
|
|
4alpha-carboxy-5alpha-cholesta-8,24-dien-3beta-ol + NADP+ <=> zymosterone + NADPH + CO2
|
1.1.1.170
3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
|
–
|
|
BRENDA:
BS422642
KEGG:
R12404
MetaCyc:
RXN66-318
|
|
|
|
10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl_acetate <=> 10-deacetyl-2-debenzoylbaccatin_III
|
not assigned
|
–
|
|
KEGG:
R06319
MetaCyc:
RXN-8863
|
|
|
|
norsolorinic_acid_anthrone + O2 <=> norsolorinic_acid + H2O
|
1.13.12.20
noranthrone monooxygenase
|
–
|
|
BRENDA:
BR50371
KEGG:
R10224
MetaCyc:
RXN-11624
|
|
|
|
UDP-glucose + abscisic_acid <=> beta-D-glucopyranosyl_abscisate + UDP
|
2.4.1.263
abscisate beta-glucosyltransferase
|
–
|
|
BRENDA:
BR49616;
BS417744
KEGG:
R07575
MetaCyc:
RXN-8155
|
|
|
|
9''-cis-neoxanthin + O2 <=> 2-cis,4-trans-xanthoxin + (3S,5R,6R)-3,5-dihydroxy-6,7-didehydro-5,6-dihydro-12''-apo-beta-caroten-12''-al
|
1.13.11.51
9-cis-epoxycarotenoid dioxygenase
|
–
|
|
BRENDA:
BR48574
KEGG:
R06952
MetaCyc:
RXN-698
|
|
|
|
ATP + 4-methoxy-2,2''-bipyrrole-5-carbaldehyde + 2-Undecylpyrrole <=> ADP + phosphate + Undecylprodigiosin + H+
|
6.4.1
|
–
|
|
KEGG:
R11673
MetaCyc:
RXN-15800
|
|
|
|
dopamine + secologanin <=> H2O + N-deacetylisoipecoside
|
4.3.3.3
deacetylisoipecoside synthase
|
–
|
|
BRENDA:
BR26150
KEGG:
R05750
MetaCyc:
4.3.3.3-RXN
|
|
|
|
AminoDAHP <=> AminoDHQ + phosphate
|
4.2.1.M26
|
–
|
|
KEGG:
R06592
MetaCyc:
RXN-9585
|
|
|
|
CTP + (2E,6E)-farnesol <=> CDP + farnesyl_phosphate + H+
|
2.7.1.216
farnesol kinase
|
–
|
|
BRENDA:
BR51976
KEGG:
R09849
MetaCyc:
RXN-11625
|
|
|
|
(13E)-8alpha-hydroxylabd-13-en-15-yl_diphosphate <=> geranylgeranyl_diphosphate + H2O
|
4.2.1.133
copal-8-ol diphosphate hydratase
4.2.3.133
alpha-copaene synthase
|
–
–
|
|
BRENDA:
BR50121
KEGG:
R09967
MetaCyc:
RXN-11772
|
|
|
|
4alpha-carboxy-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP+ <=> 3-dehydro-4-methylzymosterol + NADPH + CO2
|
1.1.1.170
3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
|
–
|
|
BRENDA:
BS422640
KEGG:
R07494
MetaCyc:
RXN66-313
|
|
|
|
ATP + malonyl-[acyl-carrier_protein] + L-glutamine + H2O <=> AMP + diphosphate + Malonamoyl-[acyl-carrier_protein] + L-glutamate
|
6.3.5
|
–
|
|
KEGG:
R11515
|
|
|
|
deacetylvindoline + acetyl-CoA <=> vindoline + CoA
|
2.3.1.107
deacetylvindoline O-acetyltransferase
|
–
|
|
BRENDA:
BR43971
KEGG:
R03230
MetaCyc:
2.3.1.107-RXN
SABIO-RK:
3056
|
|
|
|
2-Undecylpyrrole + NADP+ + H2O <=> 4-Keto-2-undecylpyrroline + NADPH + H+
|
1.17.1
|
–
|
|
KEGG:
R11663
MetaCyc:
RXN1A0-6098
|
|
|
|
festuclavine <=> fumigaclavine_B
|
not assigned
|
–
|
|
KEGG:
R12093
MetaCyc:
RXN-13479
|
|
|
|
4-coumaroyl-CoA + (4-coumaroyl)acetyl-CoA + H2O <=> bisdemethoxycurcumin + CoA + CO2
|
2.3.1.219
demethoxycurcumin synthase
|
–
|
|
BRENDA:
BR50413
KEGG:
R08807
MetaCyc:
RXN-11223
|
|
|
|
(R)-pulegone + reduced_flavodoxin + O2 <=> (+)-menthofuran + flavin + H2O
|
1.14.14.143
(+)-menthofuran synthase
|
–
|
|
BRENDA:
BR48926
KEGG:
R08923
|
|
|
|
nicotinate <=> 3,6-Dihydronicotinic_acid
|
not assigned
|
–
|
|
KEGG:
R08426
|
|
|
|
1-Dehydro-[6]-gingerdione <=> [6]-gingerol
|
not assigned
|
–
|
|
KEGG:
R08800
|
|
|
|
kanamycin_A + 2-oxoglutarate <=> 6''-Oxokanamycin_X + L-glutamate
|
2.6.1.94
2'-deamino-2'-hydroxyneamine transaminase
|
–
|
|
KEGG:
R11269
|
|
|
|
3-hydroxyechinenone + O2 + reduced_acceptor <=> adonirubin + H2O + acceptor
|
1.14.99.63
beta-carotene 4-ketolase
1.14.99.64
zeaxanthin 4-ketolase
|
–
–
|
|
KEGG:
R07566;
R07567
MetaCyc:
RXN-8215
|
|
|
|
4-hydroxy-2,2''-bipyrrole-5-methanol + NAD+ <=> 4-hydroxy-2,2''-bipyrrole-5-carbaldehyde + NADH + H+
|
1.1.1
|
–
|
|
KEGG:
R11669
MetaCyc:
RXN-15785_WOP
|
|
|
|
1-deoxy-11-oxopentalenate + O2 + NADPH + H+ <=> neopentalenolactone_D + H2O + NADP+
|
1.14.13.171
neopentalenolactone D synthase
|
–
|
|
BRENDA:
BR50266
KEGG:
R10155
MetaCyc:
RXN-12661
|
|
|
|
3,4-Dihydro-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carboxylate <=> 3,4-Dihydro-7-hydroxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carboxylate
|
1.14
|
–
|
|
KEGG:
R11363
|
|
|
|
Palustradienal <=> Palustric_acid
|
not assigned
|
–
|
|
KEGG:
R09110
|
|
|
|
L-tyrosine + H2O + O2 <=> 4-hydroxyphenylpyruvate + NH3 + H2O2
|
1.4.3.11
L-glutamate oxidase
1.4.3.14
L-lysine oxidase
1.4.3.2
L-amino-acid oxidase
|
–
–
–
|
|
BRENDA:
BS258978
KEGG:
R00729
MetaCyc:
RXN-12487
SABIO-RK:
1092
|
|
|
|
S-adenosyl-L-methionine + caffeoyl_alcohol <=> S-adenosyl-L-homocysteine + coniferyl_alcohol
|
2.1.1.104
caffeoyl-CoA O-methyltransferase
2.1.1.68
caffeate O-methyltransferase
|
–
–
|
|
BRENDA:
BS319849
KEGG:
R06575
|
|
|
|
dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-L-allose <=> dTDP-L-megosamine
|
not assigned
|
–
|
|
KEGG:
R11047
|
|
|
|
H+ + L-tryptophan <=> CO2 + tryptamine
|
4.1.1.105
L-tryptophan decarboxylase
4.1.1.28
aromatic-L-amino-acid decarboxylase
4.1.1.53
phenylalanine decarboxylase
|
–
–
–
|
|
BRENDA:
BR52265
KEGG:
R00685
MetaCyc:
AROMATIC-L-AMINO-ACID-DECARBOXYLASE-RXN
SABIO-RK:
1065
|
|
|
|
Megalomicin_A <=> Megalomicin_C2
|
not assigned
|
–
|
|
KEGG:
R06505
|
|
|
|
Aurachin_B_epoxide <=> aurachin_A
|
not assigned
|
–
|
|
KEGG:
R12054
MetaCyc:
RXN-15028
|
|
|
|
Nogalavinone <=> 1-OH-Nogalamycinone
|
not assigned
|
–
|
|
KEGG:
R09330
|
|
|
|
geranylgeranyl_diphosphate <=> ent-copalyl_diphosphate
|
5.5.1.12
copalyl diphosphate synthase
5.5.1.13
ent-copalyl diphosphate synthase
5.5.1.14
syn-copalyl-diphosphate synthase
|
–
–
–
|
|
BRENDA:
BR40507;
BR44349;
BS386478
KEGG:
R02068;
R06298;
R06312
MetaCyc:
5.5.1.13-RXN;
RXN-4861;
RXN-8528
|
|
|
|
typhasterol + NADPH + H+ + O2 <=> 24-epicastasterone + NADP+ + H2O
|
1.14
|
–
|
|
KEGG:
R07470
|
|
|
|
4-(2-amino-3-chlorophenyl)pyrrole + Cl- + O2 + FADH2 <=> aminopyrrolnitrin + H2O + FAD
|
1.14.19
|
–
|
|
KEGG:
R11106
MetaCyc:
RXN-11793
|
|
|
|
N6-(4-hydroxy-3-methyl-2-(E)-butenyl)ATP + H2O <=> N6-(4-hydroxy-3-methyl-2-(E)-butenyl)ADP + phosphate + H+
|
not assigned
|
–
|
|
KEGG:
R08063
MetaCyc:
RXN-4310
|
|
|
|
2-carboxy-1,4-naphthoquinone + phytyl_diphosphate + H+ <=> demethylphylloquinone + diphosphate + CO2
|
2.5.1.130
2-carboxy-1,4-naphthoquinone phytyltransferase
|
–
|
|
BRENDA:
BR51528
KEGG:
R12255
MetaCyc:
RXN-7568
|
|
|
|
citrate <=> cis-aconitate + H2O
|
4.2.1.117
2-methylcitrate dehydratase (2-methyl-trans-aconitate forming)
4.2.1.3
aconitate hydratase
|
–
–
|
|
BRENDA:
BR419
KEGG:
R01325
MetaCyc:
ACONITATEDEHYDR-RXN
SABIO-RK:
268
|
|
|
|
S-adenosyl-L-methionine + dTDP-4-dehydro-6-deoxy-alpha-D-gulose <=> S-adenosyl-L-homocysteine + dTDP-4-oxo-5-C-methyl-L-rhamnose
|
2.1.1
|
–
|
|
KEGG:
R11020
|
|
|
|
S-adenosyl-L-methionine + norajmaline <=> ajmaline + S-adenosyl-L-homocysteine + H+
|
2.1.1.M48
|
–
|
|
KEGG:
R05881
MetaCyc:
RXN-8221
|
|
|
|
norbelladine + NADP+ <=> Norcraugsodine + NADPH + H+
|
1.4.1
|
–
|
|
KEGG:
R11751
MetaCyc:
RXN-18121
|
|
|
|
8-ethyl-12-methyl-3-vinyl-bacteriochlorophyllide_d + H2O <=> 3-(1-hydroxyethyl)-pyrochlorophyllide_a
|
4.2.1.169
3-vinyl bacteriochlorophyllide d 31-hydratase
|
–
|
|
KEGG:
R11510
|
|
|
|
dTDP-4-dehydro-6-deoxy-D-glucose + NADPH + H+ <=> dTDP-L-rhamnose + NADP+
|
1.1.1
1.1.1.133
dTDP-4-dehydrorhamnose reductase
|
–
–
|
|
BRENDA:
BS187148
KEGG:
R08935
|
|
|
|
S-adenosyl-L-methionine + Isoandrocymbine <=> H+ + O-Methylandrocymbine + S-adenosyl-L-homocysteine
|
2.1.1
|
–
|
|
KEGG:
R08449
MetaCyc:
RXN-9207
|
|
|
|
glutaryl-CoA + flavin <=> crotonyl-CoA + CO2 + reduced_flavodoxin
|
1.3.8.6
glutaryl-CoA dehydrogenase (ETF)
|
–
|
|
BRENDA:
BR36856
KEGG:
R02488
|
|
|
|
4-hydroxyphenylpyruvate + O2 <=> (S)-2-Hydroxy-2-(4-hydroxyphenyl)acetate + CO2
|
1.13.11.46
4-hydroxymandelate synthase
|
–
|
|
BRENDA:
BR29129
KEGG:
R06632
|
|
|
|
NADH + vitamin_K + H+ <=> NAD+ + vitamin_KH2
|
1.6.5.2
NAD(P)H dehydrogenase (quinone)
7.1.1.2
NADH:ubiquinone reductase (H+-translocating)
|
–
–
|
|
BRENDA:
BS370204-a
KEGG:
R03643;
R03816
MetaCyc:
RXN-19671_WOP
|
|
|
|
UDP-glucose + N-Demethylansamitocin_P-3 <=> UDP + Ansamitocinoside_P-3
|
2.4.1
|
–
|
|
KEGG:
R09857
|
|
|
|
taxa-4(20),11-dien-5alpha,13alpha-diol <=> 10-deacetyl-2-debenzoylbaccatin_III
|
not assigned
|
–
|
|
KEGG:
R06318
MetaCyc:
RXN-8870
|
|
|
|
C-9_Reduced_nonaketamide <=> Nonaketamide_monocyclic_intermediate + 2 H2O
|
4.2.1
|
–
|
|
KEGG:
R09187
|
|
|
|
9,10-EOT <=> 10-OPDA
|
not assigned
|
–
|
|
KEGG:
R07866
|
|
|
|
(2E,6E)-farnesyl_diphosphate <=> beta-selinene + diphosphate
|
4.2.3.66
beta-selinene cyclase
|
–
|
|
BRENDA:
BR49548
KEGG:
R08546
MetaCyc:
RXN-10685
|
|
|
|
taxa-4(20),11-dien-5alpha-yl_acetate + reduced_flavodoxin + O2 <=> 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl_acetate + flavin + H2O
|
1.14.14.105
taxane 10beta-hydroxylase
|
–
|
|
BRENDA:
BR40410
KEGG:
R06309
|
|
|
|
Salbostatin_6''-phosphate + H2O <=> Salbostatin + phosphate
|
3.1.3
|
–
|
|
KEGG:
R11251
|
|
|
|
ATP + acetyl-CoA + HCO3- <=> ADP + phosphate + malonyl-CoA + H+
|
6.4.1.2
acetyl-CoA carboxylase
6.4.1.3
propionyl-CoA carboxylase
6.4.1.4
methylcrotonoyl-CoA carboxylase
|
–
–
–
|
|
BRENDA:
BR6444
KEGG:
R00742
MetaCyc:
ACETYL-COA-CARBOXYLTRANSFER-RXN
SABIO-RK:
542
|
|
|
|
N6-acetyl-N6-hydroxy-L-lysine + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine + ATP <=> aerobactin + AMP + diphosphate + H+
|
6.3.2.39
aerobactin synthase
|
–
|
|
BRENDA:
BR50215
KEGG:
R10091
MetaCyc:
RXN-13056
|
|
|
|
6-phosphogluconate + NADP+ <=> D-ribulose_5-phosphate + CO2 + NADPH
|
1.1.1.351
phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating]
1.1.1.44
phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating)
|
–
–
|
|
BRENDA:
BR29307
KEGG:
R01528
MetaCyc:
6PGLUCONDEHYDROG-RXN;
RXN-9952
|
|
|
|
S-adenosyl-L-methionine + 131-hydroxy-magnesium-protoporphyrin_IX_13-monomethyl_ester <=> 131-oxo-magnesium-protoporphyrin_IX_13-monomethyl_ester + 5''-deoxyadenosine + L-methionine + H+
|
1.21.98.3
anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase
|
–
|
|
BRENDA:
BR51846
KEGG:
R06269
MetaCyc:
RXN-8798
|
|
|
|
aklavinone + NADP+ <=> aklaviketone + NADPH + H+
|
1.1.1.362
aklaviketone reductase
|
–
|
|
BRENDA:
BR50595
KEGG:
R06682
MetaCyc:
RXN-14818
|
|
|
|
aurachin_C + O2 + NADH + H+ <=> 4-hydroxy-2-methyl-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]quinolin-3(4H)-one_1-oxide + NAD+ + H2O
|
1.14.13.222
aurachin C monooxygenase/isomerase
|
–
|
|
BRENDA:
BR51469-a
KEGG:
R11382
MetaCyc:
RXN-17335_WOP
|
|
|
|
S-adenosyl-L-methionine + (S)-3''-hydroxy-N-methylcoclaurine <=> H+ + S-adenosyl-L-homocysteine + (S)-reticuline
|
2.1.1.116
3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase
2.1.1.128
(RS)-norcoclaurine 6-O-methyltransferase
|
–
–
|
|
BRENDA:
BR1437
KEGG:
R03832
MetaCyc:
2.1.1.116-RXN
|
|
|
|
tabersonine + reduced_flavodoxin + O2 <=> 16-hydroxytabersonine + flavin + H2O
|
1.14.14.103
tabersonine 16-hydroxylase
|
–
|
|
BRENDA:
BR40411
KEGG:
R05855
|
|
|
|
gibberellin_a9 <=> gibberellin_a20
|
not assigned
|
–
|
|
KEGG:
R06332
|
|
|
|
Deamino-alpha-keto-demethylphosphinothricin <=> L-glutamyl_gamma-phosphinic_acid
|
not assigned
|
–
|
|
KEGG:
R08877
|
|
|
|
1-Methylxanthine + NADH + O2 + H+ <=> xanthine + NAD+ + formaldehyde + H2O
|
1.14.13.178
methylxanthine N1-demethylase
|
–
|
|
BRENDA:
BS422267
KEGG:
R07969
MetaCyc:
RXN-13111_WOP
|
|
|
|
5a,11a-dehydrotetracycline + reduced_coenzyme_F420 <=> tetracycline + coenzyme_F420
|
1.3.98.4
5a,11a-dehydrotetracycline reductase
|
–
|
|
BRENDA:
BR51789
KEGG:
R05459
MetaCyc:
RXN-17988
|
|
|
|
ribostamycin + NAD+ <=> 3''''-Oxoribostamycin + NADH + H+
|
1.1.1
|
–
|
|
KEGG:
R11265
|
|
|
|
7,9,12-Decaketide_intermediate_3 <=> [4,5-dihydroxy-10-oxo-3-(3-oxobutanoyl)-9,10-dihydroanthracen-2-yl]acetate
|
not assigned
|
–
|
|
KEGG:
R09325
|
|
|
|
S-adenosyl-L-methionine + Cycloartenol <=> H+ + S-adenosyl-L-homocysteine + 24(28)-methylene_cycloartanol
|
2.1.1.142
cycloartenol 24-C-methyltransferase
2.1.1.41
sterol 24-C-methyltransferase
|
–
–
|
|
BRENDA:
BS377685
KEGG:
R07481
MetaCyc:
RXN-4021
SABIO-RK:
12309
|
|
|
|
2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate + H+ <=> 2-[(2-aminoethylcarbamoyl)methyl]-2-hydroxybutanedioate + CO2
|
4.1.1.117
2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate decarboxylase
|
–
|
|
BRENDA:
BR52701
KEGG:
R12309
MetaCyc:
RXN-19821
|
|
|
|
beta-Keto-L-tyrosyl-[pcp] <=> 2-Hydroxy-beta-keto-L-tyrosyl-[pcp]
|
not assigned
|
–
|
|
KEGG:
R06764
|
|
|
|
5-aminolevulinate <=> H+ + H2O + porphobilinogen
|
4.2.1.24
porphobilinogen synthase
|
–
|
|
BRENDA:
BR22826
KEGG:
R00036
MetaCyc:
PORPHOBILSYNTH-RXN
|
|
|
|
FMNH2 + NAD+ <=> FMN + NADH + H+
|
1.14.13.7
phenol 2-monooxygenase (NADPH)
1.18.1.4
rubredoxin---NAD(P)+ reductase
1.5.1
1.5.1.30
flavin reductase (NADPH)
1.5.1.36
flavin reductase (NADH)
1.5.1.37
FAD reductase (NADH)
1.5.1.38
FMN reductase (NADPH)
1.5.1.39
FMN reductase [NAD(P)H]
1.5.1.41
riboflavin reductase [NAD(P)H]
1.5.1.42
FMN reductase (NADH)
|
–
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BR36899-a
KEGG:
R05705
MetaCyc:
FMNREDUCT-RXN_WOP;
RXN-9510
SABIO-RK:
5301
|
|
|
|
dTDP-3-N,N-dimethylamino-2,3,6-trideoxy-4-keto-D-glucose <=> dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-L-allose
|
5.1.3
|
–
|
|
KEGG:
R11046
MetaCyc:
RXN-13659
|
|
|
|
1-(3,4-Dihydroxyphenyl)-1-decene-3,5-dione + S-adenosyl-L-methionine <=> 1-Dehydro-[6]-gingerdione + S-adenosyl-L-homocysteine
|
2.1.1
|
–
|
|
KEGG:
R08803
|
|
|
|
L-phenylalanine + 2 reduced_flavodoxin + 2 O2 <=> (E)-phenylacetaldoxime + 2 flavin + CO2 + 3 H2O
|
1.14.14.40
phenylalanine N-monooxygenase
|
–
|
|
BRENDA:
BR49589
KEGG:
R09578
|
|
|
|
cathenamine + NADPH + H+ <=> Ajmalicine + NADP+
|
not assigned
|
–
|
|
KEGG:
R05847
|
|
|
|
H+ + 1'-hydroxyversicolorone + NADPH + O2 <=> versiconal_hemiacetal_acetate + NADP+ + H2O
|
not assigned
|
–
|
|
KEGG:
R10477
MetaCyc:
RXN-9487
|
|
|
|
L-serine + tetrahydrofolate <=> glycine + 5,10-methylenetetrahydrofolate + H2O
|
2.1.2.1
glycine hydroxymethyltransferase
|
–
|
|
BRENDA:
BR40573
KEGG:
R00945
MetaCyc:
GLYOHMETRANS-RXN
SABIO-RK:
95
|
|
|
|
(+/-)-1-deoxypentalenic_acid + reduced_ferredoxin_[iron-sulfur]_cluster + O2 + H+ <=> pentalenate + oxidized_ferredoxin + H2O
|
1.14.15.11
pentalenic acid synthase
|
–
|
|
BRENDA:
BR50267
KEGG:
R10158
MetaCyc:
RXNMETA-12666
|
|
|
|
L-ornithine + Carbamoyl_phosphate <=> H+ + L-citrulline + phosphate
|
2.1.3.3
ornithine carbamoyltransferase
2.1.3.6
putrescine carbamoyltransferase
3.5.3.12
agmatine deiminase
|
–
–
–
|
|
BRENDA:
BR43950;
BS140887
KEGG:
R01398
MetaCyc:
ORNCARBAMTRANSFER-RXN;
RXN-13482
SABIO-RK:
98
|
|
|
|
D-Urobilinogen + O2 <=> D-Urobilin + H2O
|
not assigned
|
–
|
|
KEGG:
R00070
MetaCyc:
RXN-16676
|
|
|
|
paraxanthine + NADPH + H+ + O2 <=> 1-Methylxanthine + NADP+ + formaldehyde + H2O
|
1.13.12
|
–
|
|
KEGG:
R07960
|
|
|
|
100-1 + dTDP-D-boivinose <=> Urdamycin_B + dTDP
|
2.4.1
|
–
|
|
KEGG:
R06660
|
|
|
|
acyl-CoA + sn-glycerol_3-phosphate <=> CoA + 2-acyl-sn-glycerol_3-phosphate
|
2.3.1.15
glycerol-3-phosphate 1-O-acyltransferase
2.3.1.198
glycerol-3-phosphate 2-O-acyltransferase
|
–
–
|
|
BRENDA:
BR50119
KEGG:
R06872
MetaCyc:
RXN-13112
|
|
|
|
7,9,12-Octaketide_intermediate_1 + NADPH + H+ <=> 7,9,12-Octaketide_intermediate_2 + NADP+
|
1.1.1
|
–
|
|
KEGG:
R09262
|
|
|
|
acetyl-CoA <=> acetoacetyl-CoA + CoA
|
1.1.1.34
hydroxymethylglutaryl-CoA reductase (NADPH)
2.3.1.155
acetyl-CoA C-myristoyltransferase
2.3.1.16
acetyl-CoA C-acyltransferase
2.3.1.38
[acyl-carrier-protein] S-acetyltransferase
2.3.1.9
acetyl-CoA C-acetyltransferase
|
–
–
–
–
–
|
|
BRENDA:
BR44092
KEGG:
R00238
MetaCyc:
ACETYL-COA-ACETYLTRANSFER-RXN
SABIO-RK:
531
|
|
|
|
O-Methylandrocymbine <=> N-Formyldemecolcine
|
not assigned
|
–
|
|
KEGG:
R08450
|
|
|
|
streptomycin + ATP <=> H+ + streptomycin_6-phosphate + ADP
|
2.7.1.72
streptomycin 6-kinase
|
–
|
|
BRENDA:
BR47799
KEGG:
R02225
MetaCyc:
STREPTOMYCIN-6-KINASE-RXN
|
|
|
|
ATP + 2-[(2-aminoethylcarbamoyl)methyl]-2-hydroxybutanedioate + L-2,3-diaminopropionic_acid <=> AMP + diphosphate + 2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate + H+
|
6.3.2.55
2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate synthase
|
–
|
|
BRENDA:
BS446108
KEGG:
R12311
MetaCyc:
RXN-19822
|
|
|
|
Lochnericine <=> Horhammericine
|
not assigned
|
–
|
|
KEGG:
R05867
|
|
|
|
S-adenosyl-L-methionine + mycinamicin_III <=> S-adenosyl-L-homocysteine + mycinamicin_IV + H+
|
2.1.1.237
mycinamicin III 3''-O-methyltransferase
|
–
|
|
BRENDA:
BR49873
KEGG:
R09823
MetaCyc:
RXN-12800
|
|
|
|
protodeoxyviolaceinate + O2 + NADH + H+ <=> protoviolaceinate + NAD+ + H2O
|
1.14.13.217
protodeoxyviolaceinate monooxygenase
1.14.13.224
violacein synthase
|
–
–
|
|
BRENDA:
BR51577-a
KEGG:
R11158;
R11374
MetaCyc:
RXN-13341_WOP;
RXN-13344_WOP
|
|
|
|
dTDP-beta-L-mycarose + erythronolide_B <=> 3-alpha-mycarosylerythronolide_B + dTDP + H+
|
2.4.1.328
erythronolide mycarosyltransferase
|
–
|
|
BRENDA:
BR50870
KEGG:
R05530
MetaCyc:
RXN-12933
|
|
|
|
acetaldehyde + H2O + NAD+ <=> acetate + NADH + H+
|
1.17.1.4
xanthine dehydrogenase
1.2.1.10
acetaldehyde dehydrogenase (acetylating)
1.2.1.18
malonate-semialdehyde dehydrogenase (acetylating)
1.2.1.19
aminobutyraldehyde dehydrogenase
1.2.1.21
glycolaldehyde dehydrogenase
1.2.1.22
lactaldehyde dehydrogenase
1.2.1.24
succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.26
2,5-dioxovalerate dehydrogenase
1.2.1.28
benzaldehyde dehydrogenase (NAD+)
1.2.1.3
aldehyde dehydrogenase (NAD+)
1.2.1.31
L-aminoadipate-semialdehyde dehydrogenase
1.2.1.32
aminomuconate-semialdehyde dehydrogenase
1.2.1.36
retinal dehydrogenase
1.2.1.39
phenylacetaldehyde dehydrogenase
1.2.1.41
glutamate-5-semialdehyde dehydrogenase
1.2.1.46
formaldehyde dehydrogenase
1.2.1.47
4-trimethylammoniobutyraldehyde dehydrogenase
1.2.1.48
long-chain-aldehyde dehydrogenase
1.2.1.5
aldehyde dehydrogenase [NAD(P)+]
1.2.1.65
salicylaldehyde dehydrogenase
1.2.1.69
fluoroacetaldehyde dehydrogenase
1.2.1.8
betaine-aldehyde dehydrogenase
1.2.1.85
2-hydroxymuconate-6-semialdehyde dehydrogenase
1.2.1.88
L-glutamate gamma-semialdehyde dehydrogenase
1.2.1.99
4-(gamma-glutamylamino)butanal dehydrogenase
|
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BS189125
KEGG:
R00710
MetaCyc:
RXN66-3
|
|
|
|
L-alanine + Vanillin <=> pyruvate + vanillylamine
|
2.6.1.119
vanillin aminotransferase
|
–
|
|
BRENDA:
BR53079
KEGG:
R12622
MetaCyc:
RXN-8925
|
|
|
|
2'-hydroxydihydrodaidzein <=> daidzein + H2O
|
4.2.1.105
2-hydroxyisoflavanone dehydratase
|
–
|
|
BRENDA:
BR48537
KEGG:
R07317
MetaCyc:
RXN-3284
SABIO-RK:
8492
|
|
|
|
S-adenosyl-L-methionine + 2,7-dihydroxy-5-methyl-1-naphthoate <=> S-adenosyl-L-homocysteine + 2-hydroxy-7-methoxy-5-methyl-1-naphthoate + H+
|
2.1.1.303
2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase
|
–
|
|
BRENDA:
BR50862
KEGG:
R10963
MetaCyc:
RXN-15306
|
|
|
|
3-Dimethylallyl-4-hydroxybenzaldehyde <=> 3-dimethylallyl-4-hydroxybenzoate
|
not assigned
|
–
|
|
KEGG:
R06763
|
|
|
|
S-adenosyl-L-methionine + dTDP-4-oxo-2,6-dideoxy-D-allose <=> S-adenosyl-L-homocysteine + dTDP-3-methyl-4-oxo-2,6-dideoxy-D-glucose + H+
|
2.1.1
|
–
|
|
KEGG:
R08933
MetaCyc:
RXN-12941
|
|
|
|
Dopaxanthin_quinone + H+ <=> betanidin
|
not assigned
|
–
|
|
KEGG:
R08829
MetaCyc:
RXN-8490
|
|
|
|
Mycinamicin_VIII + O2 + NADPH + H+ <=> Mycinamicin_VII + H2O + NADP+
|
1.14.13
|
–
|
|
KEGG:
R10875
MetaCyc:
RXN-15053
|
|
|
|
L-isoleucine + H2O + NAD+ <=> NH3 + (S)-3-methyl-2-oxopentanoate + NADH + H+
|
1.4.1.1
alanine dehydrogenase
1.4.1.2
glutamate dehydrogenase
1.4.1.20
phenylalanine dehydrogenase
1.4.1.23
valine dehydrogenase (NAD+)
1.4.1.5
L-amino-acid dehydrogenase
1.4.1.8
valine dehydrogenase (NADP+)
1.4.1.9
leucine dehydrogenase
|
–
–
–
–
–
–
–
|
|
BRENDA:
BS232308
KEGG:
R02196
MetaCyc:
ILEDEAMINE-RXN
SABIO-RK:
7740
|
|
|
|
(2S)-dihydrotricetin + 2-oxoglutarate + O2 <=> dihydromyricetin + succinate + CO2
|
1.14.11.9
flavanone 3-dioxygenase
|
–
|
|
KEGG:
R05039
MetaCyc:
RXN-7922
|
|
|
|
TDP-3-dimethylamino-4,6-dideoxy-alpha-D-glucopyranose + Protomycinolide_IV <=> Mycinamicin_VIII + dTDP + H+
|
2.4.1
|
–
|
|
KEGG:
R10876
MetaCyc:
RXN-15054
|
|
|
|
ATP + (R)-2-Aza-beta-tyrosine + pC3'p <=> AMP + diphosphate + (R)-2-Aza-beta-tyrosyl-[pcp]
|
6.2.1
|
–
|
|
KEGG:
R11392
|
|
|
|
geranylhydroquinone + reduced_flavodoxin + O2 <=> 3''''-hydroxygeranylhydroquinone + flavin + H2O
|
1.14.14.174
geranylhydroquinone 3''-hydroxylase
|
–
|
|
BRENDA:
BR49271
KEGG:
R09042
|
|
|
|
epsilon-Rhodomycin_T + H2O <=> 15-Demethoxy-epsilon-rhodomycin + methanol
|
3.1.1.95
aclacinomycin methylesterase
|
–
|
|
KEGG:
R09337
|
|
|
|
(S)-3-Chloro-beta-tyrosyl-[pcp] + FADH2 + O2 <=> (S)-3-Chloro-4,5-dihydroxy-beta-phenylalanyl-[pcp] + FAD + H2O
|
1.14.14.15
(3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[peptidyl-carrier protein SgcC2] monooxygenase
|
–
|
|
KEGG:
R10731
|
|
|
|
6alpha-Hydroxy-castasterone + O2 + reduced_flavodoxin <=> 24-epicastasterone + 2 H2O + flavin
|
1.14
|
–
|
|
KEGG:
R07451
|
|
|
|
2''-Hydroxydihydrodaidzein + NADPH + H+ <=> demethylmedicarpin + NADP+ + H2O
|
not assigned
|
–
|
|
KEGG:
R07728
|
|
|
|
geranylgeranyl_diphosphate <=> ent-copalyl_diphosphate
|
5.5.1.12
copalyl diphosphate synthase
5.5.1.13
ent-copalyl diphosphate synthase
5.5.1.14
syn-copalyl-diphosphate synthase
|
–
–
–
|
|
BRENDA:
BR40507;
BR44349;
BS386478
KEGG:
R02068;
R06298;
R06312
MetaCyc:
5.5.1.13-RXN;
RXN-4861;
RXN-8528
|
|
|
|
oripavine + 2-oxoglutarate + O2 <=> morphinone + formaldehyde + succinate + CO2
|
1.14.11.31
thebaine 6-O-demethylase
|
–
|
|
BRENDA:
BS402808
KEGG:
R03698
MetaCyc:
RXN-8151
|
|
|
|
demethylmedicarpin + reduced_flavodoxin + O2 <=> (6aS,11aS)-3,6a,9-trihydroxypterocarpan + flavin + H2O
|
1.14.14.93
3,9-dihydroxypterocarpan 6a-monooxygenase
|
–
|
|
BRENDA:
BR36760
KEGG:
R03452
|
|
|
|
H+ + prephenate <=> 3-[(4R)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate + CO2
|
4.1.1.100
prephenate decarboxylase
|
–
|
|
BRENDA:
BR51243
KEGG:
R10934
MetaCyc:
RXN-16263
|
|
|
|
ATP + 2-epi-5-epi-valiolone <=> ADP + 2-epi-5-epi-valiolone_7-phosphate + H+
|
2.7.1.188
2-epi-5-epi-valiolone 7-kinase
|
–
|
|
BRENDA:
BR51232
KEGG:
R11185
MetaCyc:
RXN-16279
|
|
|
|
saccharopine + H2O + NAD+ <=> L-glutamate + (S)-2-amino-6-oxohexanoate + NADH + H+
|
1.5.1.9
saccharopine dehydrogenase (NAD+, L-glutamate-forming)
|
–
|
|
BRENDA:
BR37178;
BS261177
KEGG:
R02313
MetaCyc:
1.5.1.9-RXN
SABIO-RK:
2273
|
|
|
|
(2E,6E)-farnesyl_diphosphate <=> aristolochene + diphosphate
|
4.2.3.9
aristolochene synthase
|
–
|
|
BRENDA:
BR47977
KEGG:
R02307
MetaCyc:
ARISTOLOCHENE-SYNTHASE-RXN
SABIO-RK:
2268
|
|
|
|
H+ + 2-C-methyl-D-erythritol_4-phosphate + CTP <=> 4-(cytidine_5''-diphospho)-2-C-methyl-D-erythritol + diphosphate
|
2.7.7.60
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
|
–
|
|
BRENDA:
BR36947
KEGG:
R05633
MetaCyc:
2.7.7.60-RXN
SABIO-RK:
5231
|
|
|
|
oxaloacetate + GTP <=> CO2 + phosphoenolpyruvate + GDP
|
4.1.1.32
phosphoenolpyruvate carboxykinase (GTP)
4.1.1.49
phosphoenolpyruvate carboxykinase (ATP)
|
–
–
|
|
BRENDA:
BR291
KEGG:
R00431
MetaCyc:
4.1.1.32-RXN
SABIO-RK:
106
|
|
|
|
Cinnamic_acid + CoA + ATP <=> cinnamoyl-CoA + AMP + diphosphate
|
6.2.1
6.2.1.12
4-coumarate---CoA ligase
6.2.1.2
medium-chain acyl-CoA ligase
6.2.1.30
phenylacetate---CoA ligase
|
–
–
–
–
|
|
BRENDA:
BS34;
BS400329
KEGG:
R02255
MetaCyc:
RXN-2001
SABIO-RK:
12839;
2225
|
|
|
|
mycinamicin_IV + O2 + NADPH + H+ <=> Mycinamicin_V + H2O + NADP+
|
1.14.13
|
–
|
|
KEGG:
R10877
MetaCyc:
RXN-15049
|
|
|
|
levopimaradienol <=> levopimaradienal
|
1.14.13
|
–
|
|
KEGG:
R06355
|
|
|
|
antheraxanthin + ascorbate <=> zeaxanthin + dehydroascorbate + H2O
|
1.23.5.1
violaxanthin de-epoxidase
|
–
|
|
BRENDA:
BR48597
KEGG:
R07179
MetaCyc:
RXN-7985
|
|
|
|
bacteriochlorophyllide_a + geranylgeranyl_diphosphate + H+ <=> geranylgeranyl-bacteriochlorophyllide_a + diphosphate
|
2.5.1.133
bacteriochlorophyll a synthase
|
–
|
|
BRENDA:
BR51756
KEGG:
R11514
MetaCyc:
RXN-8788
|
|
|
|
H+ + Cinnamic_acid + O2 + NADPH <=> H2O + NADP+ + coumaric_acid
|
1.14.13.14
trans-cinnamate 2-monooxygenase
1.14.14.91
trans-cinnamate 4-monooxygenase
|
–
–
|
|
BRENDA:
BR40436
KEGG:
R02254
MetaCyc:
TRANS-CINNAMATE-2-MONOOXYGENASE-RXN
SABIO-RK:
8733
|
|
|
|
dTDP-4-amino-4,6-dideoxy-5-C-methyl-D-allose <=> dTDP-4-dimethylamino-4,6-dideoxy-5-C-methyl-D-allose
|
2.1.1
|
–
|
|
KEGG:
R11465
|
|
|
|
3''-Phosphoadenylyl_sulfate + OA-6129_B1 <=> Adenosine_3'',5''-bisphosphate + OA-6129_C
|
2.8.2
|
–
|
|
KEGG:
R10751
|
|
|
|
dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose + 2-oxoglutarate <=> dTDP-3-dehydro-4,6-dideoxy-alpha-D-glucopyranose + L-glutamate
|
2.6.1.106
dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose transaminase
|
–
|
|
BRENDA:
BR49904
KEGG:
R06426
MetaCyc:
RXN-12768
|
|
|
|
(E)-2-methylpropanal-oxime <=> Isobutyraldoxime
|
1.14.14.41
(E)-2-methylbutanal oxime monooxygenase
|
–
|
|
BRENDA:
BR51944
KEGG:
R10034
MetaCyc:
RXN-5066
|
|
|
|
H+ + feruloyl-CoA + NADPH <=> coniferyl_aldehyde + NADP+ + CoA
|
1.2.1.44
cinnamoyl-CoA reductase
1.2.1.68
coniferyl-aldehyde dehydrogenase
|
–
–
|
|
BRENDA:
BS189226
KEGG:
R02193
MetaCyc:
RXN-1106
SABIO-RK:
2166
|
|
|
|
ferruginol + reduced_flavodoxin + O2 <=> 11-hydroxyferruginol + flavin + H2O
|
1.14.14.60
ferruginol monooxygenase
|
–
|
|
BRENDA:
BR52292
KEGG:
R11951
|
|
|
|
saccharopine + H2O + NAD+ <=> 2-oxoglutarate + L-lysine + NADH + H+
|
1.5.1.7
saccharopine dehydrogenase (NAD+, L-lysine-forming)
1.5.1.8
saccharopine dehydrogenase (NADP+, L-lysine-forming)
|
–
–
|
|
BRENDA:
BR37179
KEGG:
R00715
MetaCyc:
1.5.1.7-RXN
SABIO-RK:
1087
|
|
|
|
3beta-hydroxy-9beta-pimara-7,15-diene-19,6beta-olide + NAD+ <=> momilactone_A + NADH + H+
|
1.1.1.295
momilactone-A synthase
|
–
|
|
BRENDA:
BR48879-a
KEGG:
R08916
MetaCyc:
RXN-9290_WOP
|
|
|
|
quercetin + reduced_flavodoxin + O2 <=> myricetin + flavin + H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
|
–
|
|
KEGG:
R10258
|
|
|
|
(2S)-2-amino-4-deoxy-chorismate + FMN <=> 2-amino-2-deoxychorismate + FMNH2
|
1.3.8.t
1.3.99.24
2-amino-4-deoxychorismate dehydrogenase
|
–
–
|
|
BRENDA:
BR48881;
BS390126
KEGG:
R09559
MetaCyc:
RXN-9293
|
|
|
|
L-homocysteine + 5-methyltetrahydrofolate <=> L-methionine + tetrahydrofolate
|
2.1.1.13
methionine synthase
2.1.1.14
5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
|
–
–
|
|
BRENDA:
BR40552
KEGG:
R00946
MetaCyc:
HOMOCYSMETB12-RXN
SABIO-RK:
1260
|
|
|
|
nonaprenyl_diphosphate + 4-hydroxybenzoate <=> 4-hydroxy-3-nonaprenylbenzoate + diphosphate
|
2.5.1.39
4-hydroxybenzoate polyprenyltransferase
|
–
|
|
BRENDA:
BS354017
KEGG:
R07273
MetaCyc:
2.5.1.39-RXN
|
|
|
|
isobutyryl-CoA + 5 methylmalonyl-CoA + 7 malonyl-CoA + 9 NADPH + 9 H+ <=> 6,8a-Seco-6,8a-deoxy-5-oxoavermectin_''''1b''''_aglycone + 12 CO2 + 13 CoA + 6 H2O + 9 NADP+
|
not assigned
|
–
|
|
KEGG:
R06483
|
|
|
|
maltooligosyltrehalose + H2O <=> amylose + trehalose
|
3.2.1.141
4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase
|
–
|
|
BRENDA:
BS393520
KEGG:
R11256
MetaCyc:
3.2.1.141-RXN
|
|
|
|
D-glucose_6-phosphate + H2O <=> D-glucose + phosphate
|
3.1.3
3.1.3.1
alkaline phosphatase
3.1.3.10
glucose-1-phosphatase
3.1.3.104
5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase
3.1.3.2
acid phosphatase
3.1.3.20
phosphoglycerate phosphatase
3.1.3.23
sugar-phosphatase
3.1.3.25
inositol-phosphate phosphatase
3.1.3.26
4-phytase
3.1.3.29
N-acylneuraminate-9-phosphatase
3.1.3.38
3-phosphoglycerate phosphatase
3.1.3.4
phosphatidate phosphatase
3.1.3.58
sugar-terminal-phosphatase
3.1.3.68
2-deoxyglucose-6-phosphatase
3.1.3.8
3-phytase
3.1.3.9
glucose-6-phosphatase
3.1.7.1
prenyl-diphosphatase
3.6.1.1
inorganic diphosphatase
|
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BR15946
KEGG:
R00303
MetaCyc:
RXN0-7362;
RXN66-526
SABIO-RK:
7713;
796
|
|
|
|
strictosidine_aglycone <=> Dialdehyde
|
not assigned
|
–
|
|
KEGG:
R05844
|
|
|
|
S-adenosyl-L-methionine + dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose <=> S-adenosyl-L-homocysteine + dTDP-3-dimethylamino-3,6-dideoxy-alpha-D-galactopyranose + H+
|
2.1.1.236
dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose N,N-dimethyltransferase
|
–
|
|
BRENDA:
BR49872
KEGG:
R09821
MetaCyc:
RXN-12773
|
|
|
|
18-Carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[acp] + NADPH + H+ <=> C-9_Reduced_nonaketamide + NADP+
|
1.1.1
|
–
|
|
KEGG:
R06642
|
|
|
|
L-homoserine + NADP+ <=> L-aspartate_4-semialdehyde + NADPH + H+
|
1.1.1.3
homoserine dehydrogenase
|
–
|
|
BRENDA:
BR26051
KEGG:
R01775
MetaCyc:
HOMOSERDEHYDROG-RXN
SABIO-RK:
1868
|
|
|
|
S-adenosyl-L-methionine + (S)-Coclaurine <=> H+ + (S)-N-methylcoclaurine + S-adenosyl-L-homocysteine
|
2.1.1.115
(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase
2.1.1.140
(S)-coclaurine-N-methyltransferase
|
–
–
|
|
BRENDA:
BR29467
KEGG:
R04692
MetaCyc:
2.1.1.140-RXN
|
|
|
|
3,5,7-trioxododecanoyl-CoA <=> CoA + 2,4-dihydroxy-6-pentylbenzoate + H+
|
4.4.1.26
olivetolic acid cyclase
|
–
|
|
BRENDA:
BR50339
KEGG:
R10278
MetaCyc:
RXN-13612
|
|
|
|
phytyl_diphosphate + NADP+ <=> geranylgeranyl_diphosphate + NADPH + H+
|
1.3.1.83
geranylgeranyl diphosphate reductase
|
–
|
|
BRENDA:
BR49043
KEGG:
R02063
MetaCyc:
RXN-10625
|
|
|
|
Leucocyanidin + 2-oxoglutarate + O2 <=> taxifolin + succinate + CO2 + H2O
|
1.14.20.4
anthocyanidin synthase
|
–
|
|
KEGG:
R05723
|
|
|
|
heme + 3 reduced_flavodoxin + 3 O2 <=> Biliverdin + Fe2+ + CO + 3 flavin + 3 H2O
|
1.14.14.18
heme oxygenase (biliverdin-producing)
1.14.99.58
heme oxygenase (biliverdin-IX-beta and delta-forming)
|
–
–
|
|
BRENDA:
BR40384
KEGG:
R00311
|
|
|
|
dTDP-3-amino-4-oxo-2,3,6-trideoxy-L-allose <=> dTDP-L-ristosamine
|
not assigned
|
–
|
|
KEGG:
R11139
|
|
|
|
Oleandolide + dTDP-L-olivose <=> L-olivosyl-oleandolide + dTDP + H+
|
2.4.1
|
–
|
|
KEGG:
R06455
MetaCyc:
RXN-12804
|
|
|
|
ent-isokaurene + O2 + reduced_flavodoxin <=> ent-isokauren-2beta-ol + flavin + H2O
|
1.14.14.76
ent-isokaurene C2/C3-hydroxylase
|
–
|
|
BRENDA:
BR52394;
BS418604
KEGG:
R09861
|
|
|
|
cytidine_5''-{[hydroxy(2-hydroxypropyl)phosphonoyl]phosphate} + H2O <=> (S)-2-hydroxypropylphosphonate + CMP + H+
|
3.6.1
|
–
|
|
KEGG:
R12499
MetaCyc:
RXN-19877
|
|
|
|
chorismate <=> 3-[(1-carboxyvinyl)oxy]benzoate + H2O
|
4.2.1.151
chorismate dehydratase
|
–
|
|
BRENDA:
BR51004
KEGG:
R10666
MetaCyc:
RXN-12345
|
|
|
|
geranylgeranyl_diphosphate <=> Cembrene
|
not assigned
|
–
|
|
KEGG:
R06321
|
|
|
|
canthaxanthin + reduced_ferredoxin_[iron-sulfur]_cluster + O2 + H+ <=> adonirubin + oxidized_ferredoxin + H2O
|
1.14.15.24
beta-carotene 3-hydroxylase
|
–
|
|
BRENDA:
BS416742;
BS416744
KEGG:
R07568
MetaCyc:
RXN-8186
|
|
|
|
pyruvate + CoA + oxidized_ferredoxin <=> acetyl-CoA + CO2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+
|
1.2.7.1
pyruvate synthase
1.2.7.11
2-oxoacid oxidoreductase (ferredoxin)
1.2.7.7
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)
|
–
–
–
|
|
BRENDA:
BR29433
KEGG:
R01196
MetaCyc:
PYRUFLAVREDUCT-RXN
|
|
|
|
gibberellin_a37 <=> Gibberellin_A36
|
not assigned
|
–
|
|
KEGG:
R06325
|
|
|
|
(R)-3-(4-hydroxyphenyl)lactate + NAD+ <=> 4-hydroxyphenylpyruvate + NADH + H+
|
1.1.1.110
aromatic 2-oxoacid reductase
1.1.1.222
(R)-4-hydroxyphenyllactate dehydrogenase
1.1.1.237
hydroxyphenylpyruvate reductase
1.1.1.345
D-2-hydroxyacid dehydrogenase (NAD+)
1.1.1.37
malate dehydrogenase
1.1.1.96
diiodophenylpyruvate reductase
|
–
–
–
–
–
–
|
|
BRENDA:
BR29263-a;
BS186997
KEGG:
R03337
MetaCyc:
1.1.1.222-RXN_WOP;
HYDROXYPHENYLPYRUVATE-REDUCTASE-RXN
SABIO-RK:
3145
|
|
|
|
1-hydroxyneurosporene <=> demethylspheroidene
|
1.3.99.27
1-hydroxycarotenoid 3,4-desaturase
|
–
|
|
KEGG:
R07534
|
|
|
|
H2O + L-arginine <=> Urea + L-ornithine
|
3.5.3.1
arginase
3.5.3.7
guanidinobutyrase
|
–
–
|
|
BRENDA:
BR19260;
BS140960
KEGG:
R00551
MetaCyc:
ARGINASE-RXN
SABIO-RK:
574
|
|
|
|
Campest-4-en-3beta-ol + NAD+ <=> (24R)-ergost-4-en-3-one + NADH + H+
|
1.1.1.357
3alpha-hydroxysteroid 3-dehydrogenase
|
–
|
|
KEGG:
R07428
MetaCyc:
RXN-710
|
|
|
|
succinyl-CoA + acetate <=> succinate + acetyl-CoA
|
2.8.3.1
propionate CoA-transferase
2.8.3.18
succinyl-CoA:acetate CoA-transferase
2.8.3.8
acetate CoA-transferase
|
–
–
–
|
|
BRENDA:
BR50544
KEGG:
R10343
MetaCyc:
RXN-8807
SABIO-RK:
14383
|
|
|
|
Geissoschizine + NADP+ <=> 4,21-Dehydrogeissoschizine + NADPH
|
1.3.1.36
geissoschizine dehydrogenase
|
–
|
|
BRENDA:
BS258520
KEGG:
R03860
|
|
|
|
cyclic_dehypoxanthinyl_futalosine <=> 1,4-dihydroxy-6-naphthoate
|
1.14
|
–
|
|
KEGG:
R08589
|
|
|
|
S-adenosyl-L-methionine + (S)-canadine <=> (S)-N-methylcanadine + S-adenosyl-L-homocysteine
|
2.1.1.122
(S)-tetrahydroprotoberberine N-methyltransferase
|
–
|
|
KEGG:
R08789
MetaCyc:
RXN-13806
|
|
|
|
S-adenosyl-L-methionine + N-Demethylansamitocin_P-3 <=> S-adenosyl-L-homocysteine + Ansamitocin_P-3
|
2.1.1
|
–
|
|
KEGG:
R09856
|
|
|
|
3,6,7,8-Tetrahydroxy-2-naphthoate <=> 3-Hydroxy-6,7,8-trimethoxy-2-naphthoate
|
2.1.1
|
–
|
|
KEGG:
R11388
|
|
|
|
UWM6 <=> 2,3-Dehydro-UWM6 + H2O
|
4.2.1
|
–
|
|
KEGG:
R09342
MetaCyc:
RXN-11981
|
|
|
|
7-deoxyloganate + reduced_flavodoxin + O2 <=> loganic_acid + flavin + H2O
|
1.14.14.85
7-deoxyloganate 7-hydroxylase
|
–
|
|
BRENDA:
BR40528
KEGG:
R05832
|
|
|
|
UDP-N-acetyl-D-glucosamine + 2-deoxystreptamine <=> H+ + 2''-N-acetylparomamine + UDP
|
2.4.1.283
2-deoxystreptamine N-acetyl-D-glucosaminyltransferase
|
–
|
|
BRENDA:
BR50179
KEGG:
R08894
MetaCyc:
RXN-13122
|
|
|
|
(S)-4-Amino-5-oxopentanoate <=> 5-aminolevulinate
|
5.4.3.8
glutamate-1-semialdehyde 2,1-aminomutase
|
–
|
|
BRENDA:
BR32
KEGG:
R02272
MetaCyc:
GSAAMINOTRANS-RXN
|
|
|
|
dTDP-glucose <=> H2O + dTDP-4-dehydro-6-deoxy-D-glucose
|
4.2.1.46
dTDP-glucose 4,6-dehydratase
4.2.1.76
UDP-glucose 4,6-dehydratase
|
–
–
|
|
BRENDA:
BR425
KEGG:
R06513
MetaCyc:
DTDPGLUCDEHYDRAT-RXN
SABIO-RK:
2648;
8948
|
|
|
|
pyruvate + CoA + NAD+ <=> acetyl-CoA + CO2 + NADH
|
1.2.1.aj
1.2.4.1
pyruvate dehydrogenase (acetyl-transferring)
1.2.4.2
oxoglutarate dehydrogenase (succinyl-transferring)
1.2.4.4
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
1.8.1.4
dihydrolipoyl dehydrogenase
2.3.1.12
dihydrolipoyllysine-residue acetyltransferase
|
–
–
–
–
–
–
|
|
BRENDA:
BS231868
KEGG:
R00209
MetaCyc:
PYRUVDEH-RXN
SABIO-RK:
523
|
|
|
|
H2O + cephalosporin_C <=> H+ + acetate + deacetylcephalosporin_C
|
3.1.1.41
cephalosporin-C deacetylase
3.5.2.6
beta-lactamase
|
–
–
|
|
BRENDA:
BR19191
KEGG:
R03062
MetaCyc:
CEPHALOSPORIN-C-DEACETYLASE-RXN
SABIO-RK:
2905
|
|
|
|
(+)-borneol + NAD+ <=> (+)-Camphor + NADH + H+
|
1.1.1.198
(+)-borneol dehydrogenase
|
–
|
|
BRENDA:
BR29247
KEGG:
R02944
MetaCyc:
+-BORNEOL-DEHYDROGENASE-RXN
|
|
|
|
12-Demethyl-11,12-dehydropaspaline + O2 + NADPH + H+ <=> beta-PC-M6 + NADP+ + H2O
|
1.14.13
|
–
|
|
KEGG:
R10357
|
|
|
|
9-cis-10''-apo-beta-carotenal + O2 <=> carlactone + (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal
|
1.13.11.69
carlactone synthase
|
–
|
|
BRENDA:
BR50252
KEGG:
R10558
MetaCyc:
RXN-13643
|
|
|
|
monacolin_L_acid + O2 + reduced_flavodoxin <=> monacolin_J_acid + flavin + H2O
|
1.14.14.125
monacolin L hydroxylase
|
–
|
|
BRENDA:
BR51075
KEGG:
R10794
|
|
|
|
(-)-deoxypodophyllotoxin <=> podophyllotoxin
|
not assigned
|
–
|
|
KEGG:
R12127
|
|
|
|
acetone <=> diketone
|
not assigned
|
–
|
|
KEGG:
R09469
|
|
|
|
shikimate + NAD+ <=> 3-dehydroshikimate + NADH + H+
|
1.1.1.166
hydroxycyclohexanecarboxylate dehydrogenase
1.1.1.24
quinate dehydrogenase
1.1.1.25
shikimate dehydrogenase
1.1.1.282
quinate/shikimate dehydrogenase
|
–
–
–
–
|
|
BRENDA:
BR48020-a;
BS394992
KEGG:
R06847
MetaCyc:
RXN-11174_WOP;
RXN-20484
SABIO-RK:
12026;
6422
|
|
|
|
N2-Acetyl-L-ornithine + H2O <=> L-ornithine + acetate
|
2.3.1.35
glutamate N-acetyltransferase
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
3.5.1.16
acetylornithine deacetylase
3.5.1.17
acyl-lysine deacylase
3.5.1.B4
|
–
–
–
–
–
|
|
BRENDA:
BR19236
KEGG:
R00669
MetaCyc:
ACETYLORNDEACET-RXN
SABIO-RK:
1049
|
|
|
|
Littorine <=> L-hyoscyamine
|
not assigned
|
–
|
|
KEGG:
R08434
MetaCyc:
RXN-8255
|
|
|
|
3-hydroxy-5-methylhex-4-enoyl-CoA + NAD+ <=> 5-methyl-3-oxo-4-hexenoyl-CoA + NADH + H+
|
1.1.1.35
3-hydroxyacyl-CoA dehydrogenase
|
–
|
|
KEGG:
R08094
|
|
|
|
indole + reduced_flavodoxin + O2 <=> indolin-2-one + flavin + H2O
|
1.14.14.153
indole-2-monooxygenase
|
–
|
|
BRENDA:
BR49969
KEGG:
R07403
|
|
|
|
L-valine + 2-oxoglutarate <=> L-glutamate + 2-oxoisovalerate
|
2.6.1.39
2-aminoadipate transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.6
leucine transaminase
2.6.1.66
valine---pyruvate transaminase
|
–
–
–
–
|
|
BRENDA:
BS356553
KEGG:
R01214
MetaCyc:
BRANCHED-CHAINAMINOTRANSFERVAL-RXN
SABIO-RK:
1446
|
|
|
|
cadaverine <=> sparteine
|
not assigned
|
–
|
|
KEGG:
R08419
|
|
|
|
theophylline + NADH + O2 + H+ <=> 1-Methylxanthine + NAD+ + formaldehyde + H2O
|
1.14.13.128
7-methylxanthine demethylase
1.14.13.179
methylxanthine N3-demethylase
|
–
–
|
|
BRENDA:
BS412972
KEGG:
R07975
MetaCyc:
RXN-13110_WOP
|
|
|
|
2-hydroxyethylphosphonate + O2 <=> H+ + hydroxymethylphosphonate + formate
|
1.13.11.72
2-hydroxyethylphosphonate dioxygenase
|
–
|
|
BRENDA:
BR50255
KEGG:
R08864
MetaCyc:
RXN-10824
|
|
|
|
L-homoserine + NAD+ <=> L-aspartate_4-semialdehyde + NADH + H+
|
1.1.1.3
homoserine dehydrogenase
|
–
|
|
BRENDA:
BR26051-a
KEGG:
R01773
MetaCyc:
HOMOSERDEHYDROG-RXN_WOP
|
|
|
|
(-)-menthone + NADPH + H+ + O2 <=> (4R,7S)-7-isopropyl-4-methyloxepan-2-one + NADP+ + H2O
|
1.14.13.105
monocyclic monoterpene ketone monooxygenase
|
–
|
|
BRENDA:
BR48904
KEGG:
R08925
MetaCyc:
RXN-9441
SABIO-RK:
12386
|
|
|
|
Caffeine + NADH + O2 + H+ <=> Theobromine + NAD+ + formaldehyde + H2O
|
1.14.13.128
7-methylxanthine demethylase
1.14.13.178
methylxanthine N1-demethylase
|
–
–
|
|
BRENDA:
BR50577-a
KEGG:
R07955
MetaCyc:
RXN-11513_WOP
|
|
|
|
dopamine + Protoemetine <=> 7''-O-demethylcephaeline + H2O
|
not assigned
|
–
|
|
KEGG:
R11684
MetaCyc:
RXN-13794
|
|
|
|
L-phenylalanine + reduced_flavodoxin + O2 <=> N-hydroxy-L-phenylalanine + flavin + H2O
|
1.14.14.40
phenylalanine N-monooxygenase
|
–
|
|
BRENDA:
BR49590
KEGG:
R09579
|
|
|
|
Avermectin_B1a_monosaccharide + dTDP-L-oleandrose <=> avermectin_B1a + dTDP
|
2.4.1
|
–
|
|
KEGG:
R06489
|
|
|
|
cis-aconitate + H2O <=> isocitrate
|
4.2.1.3
aconitate hydratase
|
–
|
|
BRENDA:
BS18708
KEGG:
R01900
MetaCyc:
ACONITATEHYDR-RXN
SABIO-RK:
273
|
|
|
|
UDP-glucose + pelargonidin <=> UDP + pelargonidin_3-O-beta-D-glucoside + H+
|
2.4.1.115
anthocyanidin 3-O-glucosyltransferase
2.4.1.91
flavonol 3-O-glucosyltransferase
|
–
–
|
|
BRENDA:
BS321994
KEGG:
R06534
MetaCyc:
PELUDP-RXN
|
|
|
|
a_demethylmenaquinol + S-adenosyl-L-methionine <=> menaquinol + S-adenosyl-L-homocysteine
|
2.1.1.163
demethylmenaquinone methyltransferase
|
–
|
|
BRENDA:
BR49116
KEGG:
R09736
|
|
|
|
1-(5-phosphoribosyl)-AMP + H2O <=> N'-[(5'-phosphoribosyl)formimino]-5-aminoimidazole-4-carboxamide_ribonucleotide
|
3.5.4.19
phosphoribosyl-AMP cyclohydrolase
|
–
|
|
BRENDA:
BR26113
KEGG:
R04037
MetaCyc:
HISTCYCLOHYD-RXN
|
|
|
|
2 delta-cadinene <=> gossypol
|
not assigned
|
–
|
|
KEGG:
R08371
|
|
|
|
dihydrochanoclavine-I_aldehyde <=> 6,8-dimethyl-6,7-didehydroergoline + H2O
|
not assigned
|
–
|
|
KEGG:
R12091
MetaCyc:
RXN-13477
|
|
|
|
phosphatidylserine + H+ <=> phosphatidylethanolamine + CO2
|
4.1.1.65
phosphatidylserine decarboxylase
|
–
|
|
BRENDA:
BR326
KEGG:
R02055
MetaCyc:
PHOSPHASERDECARB-RXN
SABIO-RK:
2072
|
|
|
|
11-hydroxyferruginol + 3 reduced_flavodoxin + 3 O2 <=> carnosic_acid + 3 flavin + 4 H2O
|
1.14.14.61
carnosic acid synthase
|
–
|
|
BRENDA:
BR52293
KEGG:
R11973
|
|
|
|
chlorophyllide_a + oxidized_ferredoxin + ADP + phosphate <=> protochlorophyllide + reduced_ferredoxin_[iron-sulfur]_cluster + ATP + H2O
|
1.3.7.15
chlorophyllide a reductase
1.3.7.7
ferredoxin:protochlorophyllide reductase (ATP-dependent)
|
–
–
|
|
BRENDA:
BR49410;
BS436550
KEGG:
R06282
MetaCyc:
RXN-11902
|
|
|
|
cycloeucalenol + NADP+ <=> cycloeucalenone + NADPH + H+
|
1.1.1.270
3beta-hydroxysteroid 3-dehydrogenase
|
–
|
|
BRENDA:
BS188009
KEGG:
R12399
MetaCyc:
RXN-11929
|
|
|
|
2-cis,4-trans-xanthoxin + NAD+ <=> abscisic_aldehyde + NADH + H+
|
1.1.1.288
xanthoxin dehydrogenase
|
–
|
|
BRENDA:
BR48577
KEGG:
R06954
MetaCyc:
1.1.1.288-RXN
SABIO-RK:
9218
|
|
|
|
a_bacteriochlorophyllide_c + (2E,6E)-farnesyl_diphosphate + H+ <=> bacteriochlorophyll_c + diphosphate
|
2.5.1
2.5.1.bl
|
–
–
|
|
KEGG:
R09064
MetaCyc:
RXN-17452
|
|
|
|
dTDP-4-oxo-2,6-dideoxy-D-allose <=> dTDP-4-deoxy-4-thio-alpha-D-digitoxose
|
not assigned
|
–
|
|
KEGG:
R11470
|
|
|
|
glyoxylate + L-serine <=> Hydroxypyruvate + glycine
|
2.6.1.15
glutamine---pyruvate transaminase
2.6.1.35
glycine---oxaloacetate transaminase
2.6.1.4
glycine transaminase
2.6.1.44
alanine---glyoxylate transaminase
2.6.1.45
serine---glyoxylate transaminase
2.6.1.51
serine---pyruvate transaminase
2.6.1.60
aromatic-amino-acid---glyoxylate transaminase
|
–
–
–
–
–
–
–
|
|
BRENDA:
BR47394
KEGG:
R00588
MetaCyc:
SERINE--GLYOXYLATE-AMINOTRANSFERASE-RXN;
SERINE-GLYOXYLATE-AMINOTRANSFERASE-RXN
SABIO-RK:
987
|
|
|
|
7-deoxyloganin + reduced_flavodoxin + O2 <=> loganin + flavin + H2O
|
1.14.14.85
7-deoxyloganate 7-hydroxylase
|
–
|
|
BRENDA:
BS289300
KEGG:
R03556
|
|
|
|
10-deacetylbaccatin_III + acetyl-CoA <=> baccatin_III + CoA
|
2.3.1.167
10-deacetylbaccatin III 10-O-acetyltransferase
|
–
|
|
BRENDA:
BR44014
KEGG:
R06311
MetaCyc:
2.3.1.167-RXN
|
|
|
|
S-adenosyl-L-methionine + 7''-O-demethylcephaeline <=> cephaeline + S-adenosyl-L-homocysteine + H+
|
2.1.1
2.1.1.B83
2.1.1.B85
|
–
–
–
|
|
BRENDA:
BR49877
KEGG:
R11685
MetaCyc:
RXN-13795
|
|
|
|
Premithramycin_A2' + dTDP-D-mycarose <=> Premithramycin_A3 + dTDP + H+
|
2.4.1
|
–
|
|
KEGG:
R06718
MetaCyc:
RXN-13377
|
|
|
|
hydroxymethylphosphonate <=> Formylphosphonate
|
not assigned
|
–
|
|
KEGG:
R08865
|
|
|
|
N6-(4-hydroxy-3-methyl-2-(E)-butenyl)ADP + H2O <=> H+ + N6-(4-hydroxy-3-methyl-2-(E)-butyl)adenosine_5'-phosphate + phosphate
|
not assigned
|
–
|
|
KEGG:
R08064
MetaCyc:
RXN-4312
|
|
|
|
(S)-3-hydroxybutyryl-CoA + NAD+ <=> acetoacetyl-CoA + NADH + H+
|
1.1.1.178
3-hydroxy-2-methylbutyryl-CoA dehydrogenase
1.1.1.35
3-hydroxyacyl-CoA dehydrogenase
1.1.1.36
acetoacetyl-CoA reductase
|
–
–
–
|
|
BRENDA:
BS188053
KEGG:
R01975
MetaCyc:
RXN-11662
SABIO-RK:
2018
|
|
|
|
N-Demethyl-desepoxyansamitocin_P-3 <=> N-Demethylansamitocin_P-3
|
not assigned
|
–
|
|
KEGG:
R09855
|
|
|
|
aurachin_D + O2 + NADPH + H+ <=> aurachin_C + H2O + NADP+
|
1.14.13
|
–
|
|
KEGG:
R12051
MetaCyc:
RXN-15026
|
|
|
|
nonaprenyl_diphosphate + homogentisate + H+ <=> 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol + CO2 + diphosphate
|
2.5.1.117
homogentisate solanesyltransferase
|
–
|
|
BRENDA:
BR50960
KEGG:
R08782
MetaCyc:
RXN-2761
|
|
|
|
(2E,6E)-farnesyl_diphosphate + H2O <=> (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate
|
4.2.3.22
germacradienol synthase
|
–
|
|
BRENDA:
BR48693
KEGG:
R07647
MetaCyc:
RXN-8648
SABIO-RK:
12222
|
|
|
|
Holyrine_A <=> O-Demethyl-N-demethyl-staurosporine
|
not assigned
|
–
|
|
KEGG:
R11123
|
|
|
|
2''''''-acetyl-6''''''-deamino-6''''''-hydroxyneomycin_C + H2O <=> 6''''''-deamino-6''''''-hydroxyneomycin_C + acetate
|
3.5.1.113
2'''-acetyl-6'''-hydroxyneomycin C deacetylase
|
–
|
|
BRENDA:
BR50323
KEGG:
R08901
MetaCyc:
RXN-13177
|
|
|
|
L-phenylalanine <=> L-homophenylalanine
|
not assigned
|
–
|
|
KEGG:
R08690
|
|
|
|
5alpha-campestan-3-one + NADP+ <=> H+ + (24R)-ergost-4-en-3-one + NADPH
|
1.3.1
1.3.1.22
3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
|
–
–
|
|
KEGG:
R07429
MetaCyc:
RXN-711
|
|
|
|
N1,N5,N10-Triferuloyl_spermidine <=> N1,N5,N10-Tri(hydroxyferuloyl)_spermidine
|
1.14.13
|
–
|
|
KEGG:
R08986
|
|
|
|
3,5,7,9,11,13,15,17,19-Nonaoxo-eicosanoyl-[acp] <=> 7,9,12-Decaketide_intermediate_1
|
not assigned
|
–
|
|
KEGG:
R09260
|
|
|
|
malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> narbonolide + CoA + CO2 + H2O + NADP+
|
2.3.1.240
narbonolide synthase
|
–
|
|
BRENDA:
BR51190
KEGG:
R06459
MetaCyc:
RXN-15105
|
|
|
|
dTDP-3-methyl-4-oxo-alpha-D-ribopyranose <=> dTDP-madurosamine
|
not assigned
|
–
|
|
KEGG:
R11467
|
|
|
|
Hydroxymethylbilane <=> uroporphyrinogen_III + H2O
|
4.2.1.75
uroporphyrinogen-III synthase
|
–
|
|
BRENDA:
BR452
KEGG:
R03165
MetaCyc:
UROGENIIISYN-RXN
|
|
|
|
ATP + L-methionine + H2O <=> S-adenosyl-L-methionine + phosphate + diphosphate
|
2.5.1.6
methionine adenosyltransferase
|
–
|
|
BRENDA:
BR47590
KEGG:
R00177
MetaCyc:
S-ADENMETSYN-RXN
SABIO-RK:
96
|
|
|
|
6,7,4''-Trihydroxyflavanone + O2 + reduced_flavodoxin <=> 2,6,7,4''-Tetrahydroxyisoflavanone + H2O + flavin
|
1.14.14.87
2-hydroxyisoflavanone synthase
|
–
|
|
KEGG:
R07715
|
|
|
|
hexanoyl-[acyl-carrier_protein] + malonyl-CoA + H+ <=> norsolorinic_acid_anthrone + [acyl-carrier_protein] + CoA + CO2 + H2O
|
2.3.1.221
noranthrone synthase
|
–
|
|
BRENDA:
BR50415
KEGG:
R10239
MetaCyc:
RXN-9479
|
|
|
|
L-isoleucine + 2-oxoglutarate <=> L-glutamate + (S)-3-methyl-2-oxopentanoate
|
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.67
2-aminohexanoate transaminase
|
–
–
|
|
BRENDA:
BS356522;
BS452227
KEGG:
R02199
MetaCyc:
BRANCHED-CHAINAMINOTRANSFERILEU-RXN
SABIO-RK:
2171;
9086
|
|
|
|
S-adenosyl-L-methionine + loganic_acid <=> S-adenosyl-L-homocysteine + loganin
|
2.1.1.50
loganate O-methyltransferase
|
–
|
|
BRENDA:
BR40557
KEGG:
R03554
MetaCyc:
LOGANATE-O-METHYLTRANSFERASE-RXN
|
|
|
|
L-tyrosine + H2O + NAD+ <=> 4-hydroxyphenylpyruvate + NH3 + NADH
|
1.4.1.20
phenylalanine dehydrogenase
1.4.1.5
L-amino-acid dehydrogenase
|
–
–
|
|
BRENDA:
BS232337
KEGG:
R09830
SABIO-RK:
7284
|
|
|
|
ATP + beta-D-glucose <=> ADP + beta-D-glucose_6-phosphate
|
2.7.1.1
hexokinase
2.7.1.2
glucokinase
|
–
–
|
|
BRENDA:
BS422887
KEGG:
R01600
SABIO-RK:
1748
|
|
|
|
ent-kaur-16-ene + reduced_flavodoxin + O2 <=> ent-kaur-16-en-19-ol + flavin + H2O
|
1.14.14.86
ent-kaurene monooxygenase
|
–
|
|
BRENDA:
BR40525
KEGG:
R06291
|
|
|
|
dimethylallyl_diphosphate + brevianamide_F <=> diphosphate + tryprostatin_B
|
2.5.1.106
tryprostatin B synthase
|
–
|
|
BRENDA:
BR50540
KEGG:
R10340
MetaCyc:
RXN-14418
|
|
|
|
Stemmadenine <=> tabersonine
|
not assigned
|
–
|
|
KEGG:
R05853
|
|
|
|
8-amino-8-demethylriboflavin_5''-phosphate + H2O <=> 8-amino-8-demethyl-D-riboflavin + phosphate
|
3.1.3
|
–
|
|
KEGG:
R12114
MetaCyc:
RXN-18506
|
|
|
|
chlorophyllide_a + NADP+ <=> divinyl_chlorophyllide_a + NADPH + H+
|
1.3.1.75
3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH)
|
–
|
|
BRENDA:
BS426337
KEGG:
R06272
MetaCyc:
RXN-5286
|
|
|
|
Avermectin_A1b_monosaccharide + dTDP-L-oleandrose <=> Avermectin_A1b + dTDP
|
2.4.1
|
–
|
|
KEGG:
R06499
|
|
|
|
(2E,6E)-farnesyl_diphosphate <=> (+)-epi-isozizaene + diphosphate
|
4.2.3.37
epi-isozizaene synthase
|
–
|
|
BRENDA:
BR48983
KEGG:
R07830
MetaCyc:
RXN-9349
|
|
|
|
S-adenosyl-L-methionine + N1-Hydroxy-roquefortine_C <=> Roquefortine_F + S-adenosyl-L-homocysteine + H+
|
2.1.1
|
–
|
|
KEGG:
R12447
MetaCyc:
RXN-16146
|
|
|
|
3''-Amino-3''-deoxy-AMP + L-tyrosine <=> N6,N6,O-Tridemethylpuromycin-5''-phosphate
|
not assigned
|
–
|
|
KEGG:
R05671
|
|
|
|
5-Deoxystrigol <=> Strigol
|
1.14.13
|
–
|
|
KEGG:
R08990
|
|
|
|
copalyl_diphosphate <=> abieta-8(14),12-diene + diphosphate
|
4.2.3.32
levopimaradiene synthase
|
–
|
|
BRENDA:
BR48892
KEGG:
R06302
MetaCyc:
RXN-8511
|
|
|
|
Homospermidine <=> Trachelanthamidine
|
not assigned
|
–
|
|
KEGG:
R06724
|
|
|
|
geranyl_diphosphate <=> myrcene + diphosphate
|
4.2.3.15
myrcene synthase
4.2.3.20
(R)-limonene synthase
|
–
–
|
|
BRENDA:
BR22830
KEGG:
R02009
MetaCyc:
RXN-5110
|
|
|
|
L-lysine + 2-oxoglutarate + O2 + Cl- + H+ <=> 4-Chloro-L-lysine + succinate + CO2 + H2O
|
1.14.20
|
–
|
|
KEGG:
R12407
|
|
|
|
narbomycin + O2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> neopikromycin + oxidized_ferredoxin + H2O
|
1.14.15.33
pikromycin synthase
|
–
|
|
BRENDA:
BR50918
KEGG:
R10626
MetaCyc:
RXN-15107
|
|
|
|
(S)-tetrahydropapaverine + 2 O2 <=> papaverine + 2 H2O2
|
1.3.3.8
tetrahydroberberine oxidase
|
–
|
|
KEGG:
R11748
|
|
|
|
4''-Oxolividamine + NADPH + H+ <=> Lividamine + NADP+
|
1.1.1
|
–
|
|
KEGG:
R11276
|
|
|
|
coniferyl_aldehyde + NADPH + H+ + O2 <=> 5-hydroxyconiferaldehyde + NADP+ + H2O
|
1.14.13
|
–
|
|
KEGG:
R06572
|
|
|
|
(+)-7-Isojasmonate_CoA + H2O <=> H+ + (+)-7-Isojasmonate + CoA
|
3.1.2.20
acyl-CoA hydrolase
3.2.1
|
–
–
|
|
KEGG:
R07902
MetaCyc:
RXN-10708
|
|
|
|
Episterone + NADPH + H+ <=> episterol + NADP+
|
1.1.1
1.1.1.270
3beta-hydroxysteroid 3-dehydrogenase
|
–
–
|
|
KEGG:
R12400
MetaCyc:
RXN-11934
|
|
|
|
validone_7-phosphate <=> validamine_7-phosphate
|
not assigned
|
–
|
|
KEGG:
R11238
|
|
|
|
4-coumaroyl-CoA + 2-oxoglutarate + O2 <=> 2,4-dihydroxycinnamoyl-CoA + succinate + CO2
|
1.14.11.62
trans-4-coumaroyl-CoA 2-hydroxylase
|
–
|
|
BRENDA:
BR52905
KEGG:
R12306
MetaCyc:
RXN-12963
|
|
|
|
N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate + NAD+ + H2O <=> 2-oxoglutarate + L-2,3-diaminopropionic_acid + NADH + H+
|
1.5.1.51
N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate dehydrogenase
|
–
|
|
BRENDA:
BR51928
KEGG:
R11655
MetaCyc:
RXN-18393
|
|
|
|
5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione + L-3,4-dihydroxybutan-2-one_4-phosphate <=> H+ + 6,7-dimethyl-8-(1'-D-ribityl)lumazine + phosphate + H2O
|
2.5.1.78
6,7-dimethyl-8-ribityllumazine synthase
2.5.1.9
riboflavin synthase
|
–
–
|
|
BRENDA:
BR49183;
BS411397;
BS422660
KEGG:
R04457
MetaCyc:
LUMAZINESYN-RXN
SABIO-RK:
7642;
8561
|
|
|
|
L-asparagine <=> H+ + H2O + Beta-cyanoalanine
|
3.5.5.4
cyanoalanine nitrilase
4.2.1.65
3-cyanoalanine hydratase
|
–
–
|
|
BRENDA:
BR441
KEGG:
R01267
MetaCyc:
3-CYANOALANINE-HYDRATASE-RXN
SABIO-RK:
1484
|
|
|
|
C20916 <=> Tabtoxin
|
not assigned
|
–
|
|
KEGG:
R10890
|
|
|
|
tetrahymanol <=> squalene + H2O
|
4.2.1.123
tetrahymanol synthase
|
–
|
|
BRENDA:
BR49622
KEGG:
R02875
MetaCyc:
RXN-12337
|
|
|
|
C20914 + L-threonine <=> C20915
|
not assigned
|
–
|
|
KEGG:
R10888
|
|
|
|
tetracenomycin_B3 <=> Tetracenomycin_E
|
not assigned
|
–
|
|
KEGG:
R06702
|
|
|
|
cis-beta-D-Glucosyl-2-hydroxycinnamate + H2O <=> cis-2-hydroxycinnamate + D-glucose
|
3.2.1.21
beta-glucosidase
|
–
|
|
KEGG:
R04998
MetaCyc:
RXN-8036
|
|
|
|
versiconol + NADP+ <=> versiconal + NADPH
|
1.1.1.353
versiconal hemiacetal acetate reductase
|
–
|
|
BRENDA:
BR50506
KEGG:
R10400
MetaCyc:
RXN-9491
|
|
|
|
cis-Zeatin_riboside + H2O <=> D-ribose + cis-zeatin
|
not assigned
|
–
|
|
KEGG:
R08080
MetaCyc:
RXN-4541
|
|
|
|
ATP + 4-hydroxytryptamine <=> ADP + 4-hydroxytryptamine_4-phosphate + H+
|
2.7.1.222
4-hydroxytryptamine kinase
|
–
|
|
BRENDA:
BR52258
KEGG:
R11933
MetaCyc:
RXN-19090
|
|
|
|
acyl-CoA + lysophosphatidic_acid <=> phosphatidic_acid + CoA
|
2.3.1.51
1-acylglycerol-3-phosphate O-acyltransferase
|
–
|
|
BRENDA:
BR44053
KEGG:
R02241
MetaCyc:
RXN-1623
|
|
|
|
dimethylallyl_diphosphate + 12alpha,13alpha-dihydroxyfumitremorgin_C <=> diphosphate + fumitremorgin_B
|
2.5.1.110
12alpha,13alpha-dihydroxyfumitremorgin C prenyltransferase
|
–
|
|
BRENDA:
BR50670
KEGG:
R10457
MetaCyc:
RXN-14420
|
|
|
|
H+ + N,N-dihydroxy-L-isoleucine <=> (1E,2S)-2-methylbutanal_oxime + CO2 + H2O
|
1.14.14.38
valine N-monooxygenase
1.14.14.39
isoleucine N-monooxygenase
|
–
–
|
|
BRENDA:
BR49379
KEGG:
R10029
MetaCyc:
RXN-9639
|
|
|
|
7-chloro-L-tryptophan + O2 <=> 4-(2-amino-3-chlorophenyl)pyrrole + CO2 + 2 H2O
|
not assigned
|
–
|
|
KEGG:
R11105
|
|
|
|
H+ + sinapoyl-CoA + NADPH <=> sinapaldehyde + NADP+ + CoA
|
1.2.1.44
cinnamoyl-CoA reductase
|
–
|
|
BRENDA:
BS189224
KEGG:
R02220
MetaCyc:
RXN-1124
SABIO-RK:
2192
|
|
|
|
4-coumaroyl-CoA + malonyl-CoA + hexanoyl-CoA + H2O <=> (1E,4Z)-5-hydroxy-1-(4-hydroxyphenyl)deca-1,4-dien-3-one + 3 CoA + 2 CO2
|
not assigned
|
–
|
|
KEGG:
R08796
|
|
|
|
6-phosphogluconate + NAD+ <=> D-ribulose_5-phosphate + CO2 + NADH
|
1.1.1.343
phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating)
1.1.1.351
phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating]
1.1.1.44
phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating)
|
–
–
–
|
|
BRENDA:
BR50378
KEGG:
R10221
MetaCyc:
6PGLUCONDEHYDROG-RXN_WOP;
RXN-3341
|
|
|
|
N-hydroxy-L-tyrosine + O2 + reduced_flavodoxin <=> N,N-dihydroxy-L-tyrosine + flavin + H2O
|
1.14.14.36
tyrosine N-monooxygenase
|
–
|
|
BRENDA:
BR47356
KEGG:
R04460
|
|
|
|
cis-Prenyl-tRNA <=> cis-Zeatin_riboside_monophosphate
|
not assigned
|
–
|
|
KEGG:
R08078
MetaCyc:
RXN-4545
|
|
|
|
tetracenomycin_A2 <=> Tetracenomycin_X
|
not assigned
|
–
|
|
KEGG:
R06714
|
|
|
|
sedoheptulose_7-phosphate + D-glyceraldehyde_3-phosphate <=> D-ribose_5-phosphate + D-xylulose_5-phosphate
|
2.2.1.1
transketolase
2.2.1.3
formaldehyde transketolase
|
–
–
|
|
BRENDA:
BR43957;
BS320211
KEGG:
R01641
MetaCyc:
1TRANSKETO-RXN
|
|
|
|
NTP + AMP <=> NDP + ADP
|
2.7.4.10
nucleoside-triphosphate---adenylate kinase
|
–
|
|
BRENDA:
BR47841
KEGG:
R00333
MetaCyc:
2.7.4.10-RXN
|
|
|
|
UDP-glucose + trans-zeatin <=> H+ + O-beta-D-glucosyl-trans-zeatin + UDP
|
2.4.1.203
trans-zeatin O-beta-D-glucosyltransferase
|
–
|
|
BRENDA:
BR47514
KEGG:
R02118
MetaCyc:
RXN-4723
SABIO-RK:
9235
|
|
|
|
H+ + H2O + 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone_5'-phosphate <=> 5-amino-6-(5-phospho-D-ribosylamino)uracil + NH3
|
3.5.4.26
diaminohydroxyphosphoribosylaminopyrimidine deaminase
|
–
|
|
BRENDA:
BR26118
KEGG:
R03459
MetaCyc:
RIBOFLAVINSYNDEAM-RXN
|
|
|
|
(2E,6E)-farnesyl_diphosphate + isopentenyl_diphosphate <=> undecaprenyl_diphosphate + diphosphate
|
2.5.1.31
ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]
2.5.1.M1
|
–
–
|
|
BRENDA:
BR47468
KEGG:
R06447
MetaCyc:
RXN-8999;
RXN-9138
SABIO-RK:
12133
|
|
|
|
(-)-epiafzelechin + NADP+ <=> H+ + pelargonidin + NADPH
|
1.3.1.112
anthocyanidin reductase [(2S)-flavan-3-ol-forming]
1.3.1.77
anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]
|
–
–
|
|
BRENDA:
BS374279
KEGG:
R06541
MetaCyc:
RXN-9724
|
|
|
|
(S)-8-oxocitronellyl_enol <=> cis-trans-nepetalactol
|
5.5.1.34
(+)-cis,trans-nepetalactol synthase
|
–
|
|
BRENDA:
BR52967
KEGG:
R12520
MetaCyc:
RXN-20744
|
|
|
|
(S)-reticuline + reduced_flavodoxin + O2 <=> 1,2-dehydroreticuline + flavin + 2 H2O
|
1.14.19.54
1,2-dehydroreticuline synthase
|
–
|
|
BRENDA:
BR52350
KEGG:
R03833
|
|
|
|
isopentenyl_phosphate + ATP <=> isopentenyl_diphosphate + ADP
|
2.7.4.26
isopentenyl phosphate kinase
|
–
|
|
BRENDA:
BR50003
KEGG:
R10093
MetaCyc:
RXN-10068
|
|
|
|
1-epi-valienol_7-phosphate <=> 1,7-Diphospho-1-epi-valienol
|
not assigned
|
–
|
|
KEGG:
R11245
|
|
|
|
L-cystathionine + H2O <=> L-cysteine + 2-oxobutyrate + NH3
|
2.5.1.48
cystathionine gamma-synthase
4.4.1.1
cystathionine gamma-lyase
|
–
–
|
|
BRENDA:
BR3435
KEGG:
R01001
MetaCyc:
RXN-15130
SABIO-RK:
1294
|
|
|
|
NDP-D-mannose <=> NDP-4-oxo-6-deoxy-D-mannose
|
not assigned
|
–
|
|
KEGG:
R11430
|
|
|
|
8 malonyl-CoA + 7 NADPH + 7 H+ + [acyl-carrier_protein] <=> 3-Hydroxyhexadeca-4,6,8,10,12,14-hexaenoyl-[acp] + 8 CoA + 8 CO2 + 6 H2O + 7 NADP+
|
not assigned
|
–
|
|
KEGG:
R11435
|
|
|
|
D-glucono-1,5-lactone + H2O <=> H+ + D-gluconate
|
3.1.1.17
gluconolactonase
3.1.1.35
dihydrocoumarin hydrolase
|
–
–
|
|
BRENDA:
BR10647
KEGG:
R01519
MetaCyc:
GLUCONOLACT-RXN
|
|
|
|
1,4-dihydroxy-6-naphthoate <=> menaquinone
|
not assigned
|
–
|
|
KEGG:
R08596
|
|
|
|
1-deoxy-11beta-hydroxypentalenic_acid + NAD+ <=> 1-deoxy-11-oxopentalenate + NADH + H+
|
1.1.1.340
1-deoxy-11beta-hydroxypentalenate dehydrogenase
|
–
|
|
BRENDA:
BR50233
KEGG:
R10156
MetaCyc:
RXN-12658
|
|
|
|
S-adenosyl-L-methionine + anthranilate <=> H+ + S-adenosyl-L-homocysteine + N-Methylanthranilate
|
2.1.1.111
anthranilate N-methyltransferase
|
–
|
|
BRENDA:
BR43871
KEGG:
R00984
MetaCyc:
ANTHRANILATE-N-METHYLTRANSFERASE-RXN
|
|
|
|
ent-kaurene <=> stevioside
|
not assigned
|
–
|
|
KEGG:
R08401
|
|
|
|
S-adenosyl-L-methionine + 5-hydroxyconiferaldehyde <=> H+ + S-adenosyl-L-homocysteine + sinapaldehyde
|
2.1.1.104
caffeoyl-CoA O-methyltransferase
2.1.1.68
caffeate O-methyltransferase
|
–
–
|
|
BRENDA:
BS319578
KEGG:
R06576
MetaCyc:
RXN-1143
|
|
|
|
6,8a-Seco-6,8a-deoxy-5-oxoavermectin_''''1b''''_aglycone + NADPH + O2 <=> 5-Oxoavermectin_''''1b''''_aglycone + NADP+ + H2O
|
1.14
|
–
|
|
KEGG:
R06470
|
|
|
|
ATP + 15,173-seco-F430-173-acid <=> ADP + phosphate + coenzyme_F430
|
6.4.1.9
coenzyme F430 synthetase
|
–
|
|
BRENDA:
BR52067
KEGG:
R11629
|
|
|
|
copalyl_diphosphate <=> isopimara-7,15-diene + diphosphate
|
4.2.3.44
isopimara-7,15-diene synthase
|
–
|
|
BRENDA:
BR49051
KEGG:
R09111
MetaCyc:
RXN-8514
|
|
|
|
beta-amyrin + reduced_flavodoxin + O2 <=> 24-hydroxy-beta-amyrin + flavin + H2O
|
1.14.14.134
beta-amyrin 24-hydroxylase
|
–
|
|
BRENDA:
BR49606
KEGG:
R09604
|
|
|
|
ent-cassa-12,15-diene + O2 + reduced_flavodoxin <=> ent-11beta-hydroxycassa-12,15-diene + flavin + H2O
|
1.14.14.112
ent-cassa-12,15-diene 11-hydroxylase
|
–
|
|
BRENDA:
BR49980
KEGG:
R09866
|
|
|
|
2 N-Methyl-cyclo(L-Trp-L-Phe) <=> (-)-Ditryptophenaline
|
1
|
–
|
|
KEGG:
R12415
|
|
|
|
L-2-aminoadipate + 2-oxoglutarate <=> L-glutamate + 2-oxoadipate
|
2.6.1.39
2-aminoadipate transaminase
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
–
|
|
BRENDA:
BR47689
KEGG:
R01939
MetaCyc:
2-AMINOADIPATE-AMINOTRANSFERASE-RXN
SABIO-RK:
1992
|
|
|
|
dTDP-L-4-oxovancosamine <=> dTDP-beta-L-vancosamine
|
not assigned
|
–
|
|
KEGG:
R06630
|
|
|
|
dihydrochelirubine + reduced_flavodoxin + O2 <=> 12-hydroxydihydrochelirubine + flavin + H2O
|
1.14.14.101
dihydrochelirubine 12-monooxygenase
|
–
|
|
BRENDA:
BR654
KEGG:
R04708
|
|
|
|
LL-2,6-Diaminoheptanedioate + 2-oxoglutarate <=> (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + L-glutamate + H2O + H+
|
2.6.1.83
LL-diaminopimelate aminotransferase
|
–
|
|
BRENDA:
BR48748;
BS424856
KEGG:
R07613
MetaCyc:
RXN-7737
SABIO-RK:
12290
|
|
|
|
daidzein + reduced_flavodoxin + O2 <=> 2''-hydroxydaidzein + flavin + H2O
|
1.14.14.89
4'-methoxyisoflavone 2'-hydroxylase
1.14.14.90
isoflavone 2'-hydroxylase
|
–
–
|
|
BRENDA:
BS186719
KEGG:
R06606
|
|
|
|
S-adenosyl-L-methionine + 6-Methylsalicylyl-CoA <=> S-adenosyl-L-homocysteine + 3,6-Dimethylsalicylyl-CoA
|
2.1.1
|
–
|
|
KEGG:
R11371
|
|
|
|
zeatin_riboside + H2O <=> D-ribose + trans-zeatin
|
not assigned
|
–
|
|
KEGG:
R08073
MetaCyc:
RXN-4318
|
|
|
|
2''''''-acetyl-6''''''-hydroxyparomomycin + H2O <=> 6''''''-hydroxyparomomycin + acetate
|
3.5.1
|
–
|
|
KEGG:
R11283
MetaCyc:
RXN-13210
|
|
|
|
copalyl_diphosphate <=> miltiradiene + diphosphate
|
4.2.3.131
miltiradiene synthase
|
–
|
|
BRENDA:
BR50206
KEGG:
R10585
MetaCyc:
RXN-13338
|
|
|
|
(3Z)-phycocyanobilin + oxidized_ferredoxin <=> Biliverdin + reduced_ferredoxin_[iron-sulfur]_cluster + H+
|
1.3.7.5
phycocyanobilin:ferredoxin oxidoreductase
|
–
|
|
BRENDA:
BR40356
KEGG:
R05817
MetaCyc:
1.3.7.5-RXN
|
|
|
|
15-Demethoxy-epsilon-rhodomycin + O2 + 2 glutathione <=> beta-Rhodomycin + CO2 + H2O + GSSG
|
not assigned
|
–
|
|
KEGG:
R09338
|
|
|
|
13-dihydrocarminomycin + NADPH + H+ + O2 <=> carminomycin + NADP+ + H2O
|
1.14.13.181
13-deoxydaunorubicin hydroxylase
|
–
|
|
BRENDA:
BS421771
KEGG:
R06692
MetaCyc:
RXN-16479
|
|
|
|
131-oxo-magnesium-protoporphyrin_IX_13-monomethyl_ester + O2 + NADPH <=> divinyl_protochlorophyllide_a + NADP+ + H2O
|
1.14.13.81
magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase
|
–
|
|
BRENDA:
BR51938
KEGG:
R06267
MetaCyc:
RXN-5284
|
|
|
|
(-)-matairesinol + reduced_flavodoxin + O2 <=> (-)-pluviatolide + flavin + 2 H2O
|
1.14.19.72
(-)-pluviatolide synthase
|
–
|
|
BRENDA:
BR51591
KEGG:
R11222
|
|
|
|
phosphatidic_acid + H2O <=> diacylglycerol + phosphate
|
3.1.3.4
phosphatidate phosphatase
3.1.3.81
diacylglycerol diphosphate phosphatase
3.1.4.3
phospholipase C
|
–
–
–
|
|
BRENDA:
BR15942;
BS446013
KEGG:
R02239
MetaCyc:
PHOSPHATIDATE-PHOSPHATASE-RXN
|
|
|
|
2-deoxy-scyllo-inosamine + NAD+ <=> 3-amino-2,3-dideoxy-scyllo-inosose + NADH + H+
|
1.1.1.329
2-deoxy-scyllo-inosamine dehydrogenase
|
–
|
|
BRENDA:
BR50138-a
KEGG:
R08892
MetaCyc:
RXN-13118_WOP
|
|
|
|
narcotoline_hemiacetal + NAD+ <=> Narcotoline + NADH + H+
|
1.1.1.415
noscapine synthase
|
–
|
|
KEGG:
R11696
|
|
|
|
epicatechin + NADP+ <=> cyanidin + NADPH + H+
|
1.17.1.3
leucoanthocyanidin reductase
1.3.1.112
anthocyanidin reductase [(2S)-flavan-3-ol-forming]
1.3.1.77
anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]
|
–
–
–
|
|
BRENDA:
BS372787-a;
BS372787;
BS372788
KEGG:
R06542
MetaCyc:
RXN-17718;
RXN-17719;
RXN-9725
|
|
|
|
5,10-dihydrophenazine_1-carboxylate + O2 <=> phenazine-1-carboxylic_acid + H2O2
|
not assigned
|
–
|
|
KEGG:
R11577
MetaCyc:
RXN-17694
|
|
|
|
4-coumaroyl-CoA + quinate <=> 5-O-p-coumaroylquinic_acid + CoA
|
2.3.1.133
shikimate O-hydroxycinnamoyltransferase
2.3.1.99
quinate O-hydroxycinnamoyltransferase
|
–
–
|
|
BRENDA:
BS320439
KEGG:
R07432
MetaCyc:
RXN-2601
|
|
|
|
L-glutamine + 2-deoxy-scyllo-inosose <=> 2-Oxoglutaramate + 2-deoxy-scyllo-inosamine
|
2.6.1.100
L-glutamine:2-deoxy-scyllo-inosose aminotransferase
2.6.1.50
glutamine---scyllo-inositol transaminase
|
–
–
|
|
BRENDA:
BR50432
KEGG:
R08890
MetaCyc:
RXN-13117
|
|
|
|
L-N-acetyl-2-amino-6-oxopimelate <=> C20911
|
not assigned
|
–
|
|
KEGG:
R10884
|
|
|
|
10-deoxysarpagine + reduced_flavodoxin + O2 <=> sarpagine + flavin + H2O
|
1.14.14.136
deoxysarpagine hydroxylase
|
–
|
|
BRENDA:
BR48709
KEGG:
R05828
|
|
|
|
geraniol + reduced_flavodoxin + O2 <=> (6E)-8-hydroxygeraniol + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
1.14.14.83
geraniol 8-hydroxylase
|
–
–
|
|
BRENDA:
BR50026
KEGG:
R08785
|
|
|
|
N6,N6,O-Tridemethylpuromycin-5''-phosphate + acetyl-CoA <=> N-Acetyl-N6,N6,O-tridemethylpuromycin-5''-phosphate + CoA
|
2.3
|
–
|
|
KEGG:
R05672
|
|
|
|
tylactone + dTDP-3-dimethylamino-3,6-dideoxy-alpha-D-glucopyranose <=> 5-O-beta-D-mycaminosyltylactone + dTDP + H+
|
2.4.1.316
tylactone mycaminosyltransferase
|
–
|
|
BRENDA:
BR50949
KEGG:
R06450
MetaCyc:
RXN-15063
|
|
|
|
gamma-L-Glutamyl-[acp] <=> 4-Aminobutyryl-[acp] + CO2
|
4.1.1.95
L-glutamyl-[BtrI acyl-carrier protein] decarboxylase
|
–
|
|
KEGG:
R08907
|
|
|
|
6-Deoxydihydrokalafungin + O2 <=> Dihydrokalafungin + H2O
|
not assigned
|
–
|
|
KEGG:
R06696
|
|
|
|
acetyl-CoA + Deacetylepithienamycin_F <=> CoA + Epithienamycin_F
|
2.3.1
|
–
|
|
KEGG:
R10746
|
|
|
|
7,9,12-Decaketide_intermediate_3 <=> UWM6
|
not assigned
|
–
|
|
KEGG:
R09340
|
|
|
|
prunasin + H2O <=> (R)-mandelonitrile + D-glucose
|
3.2.1.118
prunasin beta-glucosidase
3.2.1.119
vicianin beta-glucosidase
3.2.1.21
beta-glucosidase
3.2.1.74
glucan 1,4-beta-glucosidase
|
–
–
–
–
|
|
BRENDA:
BR48183;
BS94662
KEGG:
R02558
MetaCyc:
PRUNASIN-BETA-GLUCOSIDASE-RXN
SABIO-RK:
2471
|
|
|
|
(S)-canadine + O2 + H+ <=> Berberine + H2O2
|
1.3.3.8
tetrahydroberberine oxidase
|
–
|
|
BRENDA:
BR36844
KEGG:
R02880
MetaCyc:
TETRAHYDROBERBERINE-OXIDASE-RXN
|
|
|
|
S-adenosyl-L-methionine + 131-oxo-magnesium-protoporphyrin_IX_13-monomethyl_ester <=> divinyl_protochlorophyllide_a + 5''-deoxyadenosine + L-methionine + H+
|
1.21.98.3
anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase
|
–
|
|
BRENDA:
BR51847
KEGG:
R06270
MetaCyc:
RXN-8799
|
|
|
|
(2E,6E)-farnesyl_diphosphate <=> germacrene_A + diphosphate
|
4.2.3.23
germacrene-A synthase
4.2.3.9
aristolochene synthase
|
–
–
|
|
BRENDA:
BR50766;
BS378383
KEGG:
R07649
MetaCyc:
RXN-11527
SABIO-RK:
15408
|
|
|
|
S-adenosyl-L-methionine + (S)-Norlaudanosoline <=> S-adenosyl-L-homocysteine + (S)-6-O-methylnorlaudanosoline + H+
|
2.1.1.128
(RS)-norcoclaurine 6-O-methyltransferase
|
–
|
|
KEGG:
R05214
MetaCyc:
RXN-19907
|
|
|
|
Octaketide_bicyclic_intermediate + NADPH + H+ <=> (R)-Chiral_alcohol + NADP+
|
1.1.1
|
–
|
|
KEGG:
R09309
|
|
|
|
O-ureido-L-serine <=> O-ureido-D-serine
|
5.1.1.19
O-ureido-serine racemase
|
–
|
|
BRENDA:
BR50722
KEGG:
R10488
MetaCyc:
RXN-14459
|
|
|
|
coniferyl_alcohol + NADPH + H+ + O2 <=> 5-hydroxyconiferyl_alcohol + NADP+ + H2O
|
1.14.13
|
–
|
|
KEGG:
R06573
|
|
|
|
10-deoxymethymycin + 4 reduced_ferredoxin_[iron-sulfur]_cluster + 4 H+ + 2 O2 <=> novamethymycin + 4 oxidized_ferredoxin + 2 H2O
|
1.14.15.33
pikromycin synthase
|
–
|
|
BRENDA:
BR50922
KEGG:
R10628
|
|
|
|
20,21-Diprenylterpendole_I + 3 O2 + 3 NADPH + 3 H+ <=> Lolitriol + 3 NADP+ + 4 H2O
|
1.14.13
|
–
|
|
KEGG:
R10367
|
|
|
|
L-tryptophan + L-phenylalanine <=> cyclo-L-Trp-L-Phe
|
6.3.2
|
–
|
|
KEGG:
R12413
|
|
|
|
4''-O-Methylnorbelladine + reduced_flavodoxin + O2 <=> N-Demethylnarwedine + flavin + 2 H2O
|
1.14.19
|
–
|
|
KEGG:
R08440
|
|
|
|
S-adenosyl-L-methionine + macrocin <=> tylosin + S-adenosyl-L-homocysteine + H+
|
2.1.1.101
macrocin O-methyltransferase
|
–
|
|
BRENDA:
BR43860
KEGG:
R02858
MetaCyc:
MACROCIN-O-METHYLTRANSFERASE-RXN
|
|
|
|
2''-deamino-2''-hydroxy-6''-dehydroparomamine + L-glutamate <=> 2''-deamino-2''-hydroxyneamine + 2-oxoglutarate
|
2.6.1.94
2'-deamino-2'-hydroxyneamine transaminase
|
–
|
|
BRENDA:
BR50193
KEGG:
R10094
MetaCyc:
RXN-13127
|
|
|
|
trans-cinnamate <=> cocaine
|
not assigned
|
–
|
|
KEGG:
R06745
|
|
|
|
alkane <=> R-CHOH-R'
|
not assigned
|
–
|
|
KEGG:
R09467
MetaCyc:
RXN-1022
|
|
|
|
deacetylcephalosporin_C + Carbamoyl_phosphate <=> 7beta-(5-D-Aminoadipamido)-3-carbamoyloxymethylceph-3-em-4-carboxylic_acid + phosphate
|
2.1.3.7
3-hydroxymethylcephem carbamoyltransferase
|
–
|
|
BRENDA:
BS320114
KEGG:
R05230
MetaCyc:
RXN-8810
|
|
|
|
S-adenosyl-L-methionine + (S)-6-O-methylnorlaudanosoline <=> S-adenosyl-L-homocysteine + 3''-Hydroxy-N-methyl-(S)-coclaurine
|
2.1.1.115
(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase
|
–
|
|
KEGG:
R08794
|
|
|
|
4-Deoxy-4-thio-alpha-D-digitoxosyl-calicheamicin_T0 + 5-Iodo-2,3-dimethoxyorsellinate-[acp] <=> Calicheamicin_PsAg + [acyl-carrier_protein]
|
not assigned
|
–
|
|
KEGG:
R11419
|
|
|
|
3-hydroxyindolin-2-one + reduced_flavodoxin + O2 <=> 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + flavin + H2O
|
1.14.14.109
3-hydroxyindolin-2-one monooxygenase
|
–
|
|
BRENDA:
BR49971
KEGG:
R07422
|
|
|
|
Fe-coproporphyrin_III + H2O2 + H+ <=> heme + CO2 + H2O
|
1.3.98.5
hydrogen peroxide-dependent heme synthase
|
–
|
|
BRENDA:
BR52578
KEGG:
R11522
MetaCyc:
RXN-17519
|
|
|
|
N-Methylanthranilate + ATP + CoA <=> N-methylanthraniloyl-CoA + AMP + diphosphate
|
6.2.1
6.2.1.32
anthranilate---CoA ligase
|
–
–
|
|
KEGG:
R07416
MetaCyc:
RXN-9504
|
|
|
|
erythromycin + O2 <=> Erythromycin_E + H2O
|
not assigned
|
–
|
|
KEGG:
R05519
|
|
|
|
Landomycin_D <=> Landomycin_E
|
not assigned
|
–
|
|
KEGG:
R09349
|
|
|
|
N-Demethyl-desepoxymaytansinol + isobutyryl-CoA <=> N-Demethyl-desepoxyansamitocin_P-3 + CoA
|
not assigned
|
–
|
|
KEGG:
R09854
|
|
|
|
versiconol_acetate + H2O <=> versiconol + acetate
|
3.1.1.94
versiconal hemiacetal acetate esterase
|
–
|
|
BRENDA:
BR50546
KEGG:
R10398
MetaCyc:
RXN-9493
|
|
|
|
(2E,6E)-farnesyl_diphosphate + 4-hydroxy-2-methylquinoline <=> aurachin_D + diphosphate
|
2.5.1
|
–
|
|
KEGG:
R12050
MetaCyc:
RXN-15022
|
|
|
|
lycopene <=> gamma-carotene
|
5.5.1.19
lycopene beta-cyclase
|
–
|
|
BRENDA:
BS417227
KEGG:
R05341
MetaCyc:
RXN1F-150
|
|
|
|
methylglyoxal + D-fructose_1,6-bisphosphate <=> D-glyceraldehyde_3-phosphate + 1-deoxy-D-threo-hexo-2,5-diulose_6-phosphate
|
2.2.1.11
6-deoxy-5-ketofructose 1-phosphate synthase
|
–
|
|
BRENDA:
BR50117
KEGG:
R10049
MetaCyc:
RXN-10053
|
|
|
|
S-adenosyl-L-methionine + dehypoxanthine_futalosine <=> cyclic_dehypoxanthinyl_futalosine + L-methionine + 5''-deoxyadenosine + H+
|
1.21.98.1
cyclic dehypoxanthinyl futalosine synthase
|
–
|
|
BRENDA:
BR50934
KEGG:
R08588
MetaCyc:
RXN-10620
|
|
|
|
1-guanidino-1-deoxy-scyllo-inositol <=> 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol
|
not assigned
|
–
|
|
KEGG:
R08843
|
|
|
|
Dopaxanthin + O2 <=> Dopaxanthin_quinone + H2O
|
1.10.3
1.14.18.1
tyrosinase
|
–
–
|
|
KEGG:
R08828
MetaCyc:
RXN-8489
SABIO-RK:
8187
|
|
|
|
riboflavin + ATP <=> FMN + ADP + H+
|
2.7.1.161
CTP-dependent riboflavin kinase
2.7.1.26
riboflavin kinase
|
–
–
|
|
BRENDA:
BR47765
KEGG:
R00549
MetaCyc:
RIBOFLAVINKIN-RXN
SABIO-RK:
277
|
|
|
|
thebaine + 2-oxoglutarate + O2 <=> neopinone + formaldehyde + succinate + CO2
|
1.14.11.31
thebaine 6-O-demethylase
|
–
|
|
BRENDA:
BR49145
KEGG:
R05126
MetaCyc:
RXN-8147
|
|
|
|
L-glutamine + 3-amino-2,3-dideoxy-scyllo-inosose <=> 2-Oxoglutaramate + 2-deoxystreptamine
|
2.6.1.101
L-glutamine:3-amino-2,3-dideoxy-scyllo-inosose aminotransferase
2.6.1.50
glutamine---scyllo-inositol transaminase
|
–
–
|
|
BRENDA:
BR50433;
BS356687
KEGG:
R08891
MetaCyc:
RXN-13119
|
|
|
|
neomycin_C <=> neomycin
|
5.1.3
|
–
|
|
KEGG:
R08904
MetaCyc:
RXN-13205
|
|
|
|
Terpendole_J + dimethylallyl_diphosphate <=> 20,21-Diprenylterpendole_J + diphosphate
|
2.5.1
|
–
|
|
KEGG:
R10384
MetaCyc:
RXN-15962
|
|
|
|
abietadienol + reduced_flavodoxin + O2 <=> abietadienal + flavin + H2O
|
1.14.14.145
abieta-7,13-dien-18-ol hydroxylase
|
–
|
|
BRENDA:
BS387688
KEGG:
R06354
|
|
|
|
S-adenosyl-L-methionine + magnesium_protoporphyrin_IX <=> S-adenosyl-L-homocysteine + magnesium_protoporphyrin_monomethyl_ester
|
2.1.1.11
magnesium protoporphyrin IX methyltransferase
|
–
|
|
BRENDA:
BR43869
KEGG:
R04237
MetaCyc:
RXN-MG-PROTOPORPHYRIN-METHYLESTER-SYN
SABIO-RK:
3947
|
|
|
|
3-(2''-Methylthio)ethylmalic_acid + NAD+ <=> 2-Oxo-5-methylthiopentanoic_acid + CO2 + NADH + H+
|
1.1.1
|
–
|
|
KEGG:
R08621
|
|
|
|
4''-O-methylnorbelladine + reduced_flavodoxin + O2 <=> (10bS,4aR)-noroxomaritidine + flavin + 2 H2O
|
1.14.19.50
noroxomaritidine synthase
|
–
|
|
BRENDA:
BR51838
KEGG:
R11483
|
|
|
|
UWM6 + dTDP-D-boivinose <=> C1''-C9-Glycosylated_UWM6 + dTDP
|
2.4.1
|
–
|
|
KEGG:
R09345
|
|
|
|
aclacinomycin_T + H2O <=> 15-demethylaclacinomycin_T + methanol + H+
|
3.1.1.95
aclacinomycin methylesterase
|
–
|
|
BRENDA:
BR50683
KEGG:
R10545
MetaCyc:
RXN-14703
|
|
|
|
Phosphinothricin + acetyl-CoA <=> H+ + CoA + N-acetylphosphinothricin
|
2.3.1.183
phosphinothricin acetyltransferase
|
–
|
|
BRENDA:
BR48843
KEGG:
R08938
MetaCyc:
RXN-9382
SABIO-RK:
14593
|
|
|
|
5''''-phosphoribosylparomamine + H2O <=> 5-Ribosylparomamine + phosphate
|
3.1.3
|
–
|
|
KEGG:
R11281
MetaCyc:
RXN-13208
|
|
|
|
gamma-L-glutamyl-butirosin_B <=> butirosin_B + 5-oxoproline
|
4.3.2.6
gamma-L-glutamyl-butirosin B gamma-glutamyl cyclotransferase
|
–
|
|
BRENDA:
BR50209
KEGG:
R08910
MetaCyc:
RXN-13218
|
|
|
|
(3R)-2''-hydroxydihydrodaidzein + NADP+ <=> 2''-hydroxydaidzein + NADPH + H+
|
1.3.1.51
2'-hydroxydaidzein reductase
|
–
|
|
BRENDA:
BR1199
KEGG:
R03962
MetaCyc:
RXN-4502
|
|
|
|
geranylgeranyl_diphosphate <=> ent-copalyl_diphosphate
|
5.5.1.12
copalyl diphosphate synthase
5.5.1.13
ent-copalyl diphosphate synthase
5.5.1.14
syn-copalyl-diphosphate synthase
|
–
–
–
|
|
BRENDA:
BR40507;
BR44349;
BS386478
KEGG:
R02068;
R06298;
R06312
MetaCyc:
5.5.1.13-RXN;
RXN-4861;
RXN-8528
|
|
|
|
N3-fumarylcarboxyamido-L-2,3-diaminopropionic_acid + L-leucine + ATP <=> 3-{[(2E)-4-amino-4-oxobut-2-enoyl]amino}-L-alanyl-L-leucine + ADP + phosphate + H+
|
6.3.2.47
dapdiamide synthase
|
–
|
|
BRENDA:
BR51332
KEGG:
R10944
MetaCyc:
RXN-16293
|
|
|
|
(R)-2,3-dihydroxy-3-methylbutanoate <=> 2-oxoisovalerate + H2O
|
4.2.1.9
dihydroxy-acid dehydratase
|
–
|
|
KEGG:
R04441
MetaCyc:
DIHYDROXYISOVALDEHYDRAT-RXN
|
|
|
|
Landomycin_H <=> 8-D-Olivosyl-landomycin
|
not assigned
|
–
|
|
KEGG:
R09357
|
|
|
|
N-acetylpuromycin + H2O <=> puromycin + acetate
|
not assigned
|
–
|
|
KEGG:
R05677
MetaCyc:
RXN-9453
|
|
|
|
chlorophyllide_a + H+ <=> pheophorbide_a + Mg2+
|
4.99.1.10
magnesium dechelatase
|
–
|
|
BRENDA:
BR52077
KEGG:
R09033
MetaCyc:
RXN-7739
|
|
|
|
S-adenosyl-L-methionine + cytidine_5''-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} + reduced_acceptor <=> 5''-deoxyadenosine + L-methionine + S-adenosyl-L-homocysteine + cytidine_5''-{[hydroxy(2-hydroxypropyl)phosphonoyl]phosphate} + acceptor + H+
|
2.1.1.308
cytidylyl-2-hydroxyethylphosphonate methyltransferase
|
–
|
|
KEGG:
R12497
MetaCyc:
RXN-9010
|
|
|
|
7,9,12-Octaketide_intermediate_3 <=> Octaketide_bicyclic_intermediate + H2O
|
4
|
–
|
|
KEGG:
R09305
|
|
|
|
6-methylpretetramide + NADPH + O2 + H+ <=> 4-hydroxy-6-methylpretetramide + NADP+ + H2O
|
1.14.13.232
6-methylpretetramide 4-monooxygenase
|
–
|
|
BRENDA:
BR51807
KEGG:
R05463
MetaCyc:
RXN-17981
|
|
|
|
miltiradiene <=> abieta-8,11,13-triene
|
not assigned
|
–
|
|
KEGG:
R10727
|
|
|
|
N1,N5,N10-Tricaffeoyl_spermidine <=> N1,N5,N10-Triferuloyl_spermidine
|
2.1.1
|
–
|
|
KEGG:
R08985
|
|
|
|
gibberellin_A12 + O2 + 2-oxoglutarate <=> gibberellin_a15 + CO2 + succinate
|
1.14.11
1.14.11.12
gibberellin-44 dioxygenase
|
–
–
|
|
KEGG:
R06322
MetaCyc:
RXN1F-162
SABIO-RK:
5904
|
|
|
|
paraxanthine + O2 + H2O <=> 1,7-dimethyluric_acid + H2O2
|
1.17.3.2
xanthine oxidase
|
–
|
|
BRENDA:
BS375516
KEGG:
R07977
MetaCyc:
RXN-11520
|
|
|
|
Antibiotic_JI-20B <=> gentamicin_C2
|
not assigned
|
–
|
|
KEGG:
R11304
|
|
|
|
eriodictyol + reduced_flavodoxin + O2 <=> pentahydroxyflavanone + flavin + H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
|
–
|
|
KEGG:
R04902
|
|
|
|
trans-geranic_acid + CoA <=> trans-Geranyl-CoA + H2O
|
2.8.3
|
–
|
|
KEGG:
R08097
|
|
|
|
beta-carotene <=> echinenone
|
not assigned
|
–
|
|
KEGG:
R12179
|
|
|
|
34a-Deoxy-rifamycin_W <=> Rifamycin_W
|
not assigned
|
–
|
|
KEGG:
R06991
|
|
|
|
4-coumaroyl-CoA + spermidine <=> N1,N5,N10-Tricoumaroyl_spermidine + CoA + H+
|
2.3.1.M34
|
–
|
|
KEGG:
R08983
MetaCyc:
RXN-11257
|
|
|
|
O2 + N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine <=> H2O + isopenicillin_N
|
1.21.3.1
isopenicillin-N synthase
|
–
|
|
BRENDA:
BR40531;
BS394923
KEGG:
R04872
MetaCyc:
1.21.3.1-RXN
SABIO-RK:
4514
|
|
|
|
UDP-glucose + (S)-4-hydroxymandelonitrile <=> H+ + UDP + Dhurrin
|
2.4.1.85
cyanohydrin beta-glucosyltransferase
|
–
|
|
BRENDA:
BR44255
KEGG:
R04296
MetaCyc:
RXN-743
|
|
|
|
L-glutamate_5-semialdehyde + phosphate + NADP+ <=> L-5-glutamyl_phosphate + NADPH + H+
|
1.2.1.41
glutamate-5-semialdehyde dehydrogenase
|
–
|
|
BRENDA:
BR36782
KEGG:
R03313
MetaCyc:
GLUTSEMIALDEHYDROG-RXN
SABIO-RK:
3127
|
|
|
|
(2E,6E)-farnesol + NADP+ <=> (2E,6E)-farnesal + NADPH + H+
|
1.1.1.21
aldose reductase
1.1.1.216
farnesol dehydrogenase (NADP+)
|
–
–
|
|
BRENDA:
BR33672
KEGG:
R03264
MetaCyc:
FARNESOL-DEHYDROGENASE-RXN
|
|
|
|
(S)-3-acetyloctanal + amino_acid <=> 2-Methyl-3-n-amyl-dihydropyrrole + a_2-oxo_carboxylate
|
2.6.1
|
–
|
|
KEGG:
R11672
|
|
|
|
feruloyl-CoA + H2O <=> 4-hydroxy-3-methoxyphenyl-beta-hydroxypropionyl-CoA
|
4.1.2.61
feruloyl-CoA hydratase/lyase
4.2.1.101
trans-feruloyl-CoA hydratase
|
–
–
|
|
BRENDA:
BR22824
KEGG:
R05772
MetaCyc:
4.2.1.101-RXN
|
|
|
|
S-adenosyl-L-methionine + phosphatidylethanolamine <=> phosphatidyl-N-methylethanolamine + S-adenosyl-L-homocysteine + H+
|
2.1.1.17
phosphatidylethanolamine N-methyltransferase
|
–
|
|
BRENDA:
BR43883
KEGG:
R02056
MetaCyc:
2.1.1.17-RXN
SABIO-RK:
2073
|
|
|
|
delta-carotene <=> epsilon-carotene
|
5.5.1.18
lycopene epsilon-cyclase
|
–
|
|
BRENDA:
BS427425
KEGG:
R07840
MetaCyc:
RXN-8028
|
|
|
|
3,4-Dihydro-7-methoxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carboxylic_acid <=> 3,4-Dihydro-7-methoxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carbonyl-CoA
|
not assigned
|
–
|
|
KEGG:
R11365
|
|
|
|
S-(4-Methylthiobutylthiohydroximoyl)-L-cysteine + H2O <=> an_(E)-omega-(methylthio)alkyl-thiohydroximate + pyruvate + NH3
|
4.4.1
4.4.1.13
cysteine-S-conjugate beta-lyase
|
–
–
|
|
KEGG:
R08667
MetaCyc:
RXN-8052
|
|
|
|
H+ + 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate <=> indole-3-glycerol_phosphate + CO2 + H2O
|
4.1.1.48
indole-3-glycerol-phosphate synthase
|
–
|
|
BRENDA:
BR307
KEGG:
R03508
MetaCyc:
IGPSYN-RXN
SABIO-RK:
3296
|
|
|
|
L-threonine <=> 2-oxobutyrate + NH3
|
4.2.3.1
threonine synthase
4.3.1.17
L-serine ammonia-lyase
4.3.1.19
threonine ammonia-lyase
|
–
–
–
|
|
BRENDA:
BR22834
KEGG:
R00996
MetaCyc:
THREDEHYD-RXN
SABIO-RK:
1290
|
|
|
|
ent-copalyl_diphosphate <=> ent-sandaracopimara-8(14),15-diene + diphosphate
|
4.2.3.19
ent-kaurene synthase
4.2.3.29
ent-sandaracopimaradiene synthase
|
–
–
|
|
BRENDA:
BR48889
KEGG:
R09120
MetaCyc:
RXN-4884
|
|
|
|
S-adenosyl-L-methionine + palmatine + NADPH <=> S-adenosyl-L-homocysteine + corydaline + NADP+
|
2.1.1.147
corydaline synthase
|
–
|
|
BRENDA:
BR43878
KEGG:
R07241
MetaCyc:
2.1.1.147-RXN
|
|
|
|
(1''S)-averantin + reduced_flavodoxin + O2 <=> (1''S,5''R)-5''-hydroxyaverantin + flavin + H2O
|
1.14.14.116
averantin hydroxylase
|
–
|
|
BRENDA:
BR50522
KEGG:
R10318
|
|
|
|
S-adenosyl-L-methionine + dihydrodemethylsterigmatocystin <=> H+ + dihydrosterigmatocystin + S-adenosyl-L-homocysteine
|
2.1.1.109
demethylsterigmatocystin 6-O-methyltransferase
|
–
|
|
BRENDA:
BS319593
KEGG:
R10403
MetaCyc:
RXN-9500
|
|
|
|
1,3-dihydroxy-N-methylacridone <=> Melicopicine
|
not assigned
|
–
|
|
KEGG:
R08470
|
|
|
|
protein_C-terminal_S-farnesyl-L-cysteine_methyl_ester <=> S-(2E,6E)-farnesyl-L-cysteine
|
not assigned
|
–
|
|
KEGG:
R09847
|
|
|
|
(6E)-8-hydroxylinalool + reduced_flavodoxin + O2 <=> (6E)-8-oxolinalool + flavin + 2 H2O
|
1.14.14.84
linalool 8-monooxygenase
|
–
|
|
BRENDA:
BR50025
KEGG:
R09924
|
|
|
|
trans-Geranyl-CoA <=> geranoyl-CoA
|
5.2.1
|
–
|
|
KEGG:
R08098
|
|
|
|
(R)-5-phosphomevalonate + ATP <=> 5-diphosphomevalonate + ADP
|
2.7.4.2
phosphomevalonate kinase
|
–
|
|
BRENDA:
BR48074
KEGG:
R03245
MetaCyc:
PHOSPHOMEVALONATE-KINASE-RXN
SABIO-RK:
3066
|
|
|
|
Roquefortine_C + reduced_flavodoxin + O2 <=> N1-Hydroxy-roquefortine_C + flavin + H2O
|
1.14.14
|
–
|
|
KEGG:
R12444
|
|
|
|
L-tyrosine + 2-oxoglutarate <=> 4-hydroxyphenylpyruvate + L-glutamate
|
2.6.1.1
aspartate transaminase
2.6.1.2
alanine transaminase
2.6.1.24
diiodotyrosine transaminase
2.6.1.27
tryptophan transaminase
2.6.1.39
2-aminoadipate transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.49
dihydroxyphenylalanine transaminase
2.6.1.5
tyrosine transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.7
kynurenine---oxoglutarate transaminase
2.6.1.79
glutamate---prephenate aminotransferase
2.6.1.9
histidinol-phosphate transaminase
|
–
–
–
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BR47696
KEGG:
R00734
MetaCyc:
TYROSINE-AMINOTRANSFERASE-RXN
SABIO-RK:
1097
|
|
|
|
L-proline + NAD+ <=> L-pyrroline-5-carboxylate + NADH + H+
|
1.2.1.88
L-glutamate gamma-semialdehyde dehydrogenase
1.5.1.2
pyrroline-5-carboxylate reductase
1.5.1.20
methylenetetrahydrofolate reductase [NAD(P)H]
1.5.5.2
proline dehydrogenase
|
–
–
–
–
|
|
BRENDA:
BR36895-a;
BS439688
KEGG:
R01248
MetaCyc:
PYRROLINECARBREDUCT-RXN_WOP
SABIO-RK:
1468
|
|
|
|
levopimaradienal <=> Levopimaric_acid
|
not assigned
|
–
|
|
KEGG:
R06358
|
|
|
|
UDP-glucose + dihydrozeatin <=> H+ + Dihydrozeatin-O-glucoside + UDP
|
2.4.1
|
–
|
|
KEGG:
R08076
MetaCyc:
RXN-4726
|
|
|
|
(1S,2R,3S,4S,5R,6S)-4-amino-2-carbamimidamido-3,5,6-trihydroxycyclohexyl_phosphate + L-arginine <=> streptidine_6-phosphate + L-ornithine
|
not assigned
|
–
|
|
KEGG:
R05547
MetaCyc:
RXN-11099
|
|
|
|
Coproporphyrinogen-III + O2 + H+ <=> protoporphyrinogen-IX + CO2 + H2O
|
1.3.3.3
coproporphyrinogen oxidase
|
–
|
|
BRENDA:
BR36839
KEGG:
R03220
MetaCyc:
RXN0-1461
|
|
|
|
secologanin <=> gentiopicroside
|
not assigned
|
–
|
|
KEGG:
R08500
|
|
|
|
L-glutamate + acetyl-CoA <=> H+ + N-acetyl-L-glutamate + CoA
|
2.3.1.1
amino-acid N-acetyltransferase
2.3.1.17
aspartate N-acetyltransferase
2.3.1.183
phosphinothricin acetyltransferase
2.7.2.8
acetylglutamate kinase
6.3.4.16
carbamoyl-phosphate synthase (ammonia)
|
–
–
–
–
–
|
|
BRENDA:
BR43962
KEGG:
R00259
MetaCyc:
N-ACETYLTRANSFER-RXN
SABIO-RK:
764
|
|
|
|
3''''-hydroxy-geranylhydroquinone <=> deoxyshikonin
|
not assigned
|
–
|
|
KEGG:
R09043
MetaCyc:
RXN-8923
|
|
|
|
(3E)-3-[(4S)-4-hydroxycyclohex-2-en-1-ylidene]-2-oxopropanoate <=> 3-[(2E,5R)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-ylidene]-2-oxopropanoate
|
not assigned
|
–
|
|
KEGG:
R11066
|
|
|
|
avenasterol + NADP+ <=> avenastenone + NADPH + H+
|
1.1.1.270
3beta-hydroxysteroid 3-dehydrogenase
|
–
|
|
BRENDA:
BS188006
KEGG:
R12401
MetaCyc:
RXN-11939
|
|
|
|
H+ + isochorismate + 2-oxoglutarate <=> (1R,2S,5S,6S)-2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate + CO2
|
2.2.1.9
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase
|
–
|
|
BRENDA:
BR48908
KEGG:
R08165
MetaCyc:
2.5.1.64-RXN
SABIO-RK:
12389
|
|
|
|
(E)-phenylacetaldoxime + L-cysteine + NADPH + O2 + H+ <=> S-(Phenylacetothiohydroximoyl)-L-cysteine + NADP+ + 2 H2O
|
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
|
|
KEGG:
R10670
|
|
|
|
(-)-menthone + NADP+ <=> (R)-pulegone + NADPH + H+
|
1.3.1.81
(+)-pulegone reductase
|
–
|
|
BRENDA:
BR48922
KEGG:
R06419
MetaCyc:
RXN-5163
|
|
|
|
Premithramycinone + dTDP-D-boivinose <=> Premithramycin_A1 + dTDP + H+
|
2.4.1
|
–
|
|
KEGG:
R06716
MetaCyc:
RXN-13375
|
|
|
|
L-cysteine + H2O <=> L-serine + Sulfide
|
2.5.1.47
cysteine synthase
2.5.1.49
O-acetylhomoserine aminocarboxypropyltransferase
4.2.1.22
cystathionine beta-synthase
|
–
–
–
|
|
BRENDA:
BS1928
KEGG:
R00891
MetaCyc:
RXN-19038
SABIO-RK:
1214
|
|
|
|
Gibberellin_19 + O2 + 2-oxoglutarate <=> H+ + gibberellin_a20 + CO2 + succinate
|
1.14.11
1.14.11.12
gibberellin-44 dioxygenase
|
–
–
|
|
KEGG:
R03807
MetaCyc:
RXN1F-169
|
|
|
|
aurachin_C + O2 + NADPH + H+ <=> 4-hydroxy-2-methyl-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]quinolin-3(4H)-one_1-oxide + NADP+ + H2O
|
1.14.13.222
aurachin C monooxygenase/isomerase
|
–
|
|
BRENDA:
BR51469
KEGG:
R11383
MetaCyc:
RXN-17335
|
|
|
|
L-histidinal + NAD+ + H2O <=> H+ + L-histidine + NADH
|
1.1.1.23
histidinol dehydrogenase
|
–
|
|
BRENDA:
BS187855
KEGG:
R01163
MetaCyc:
HISTALDEHYD-RXN
|
|
|
|
geranyl_diphosphate + 4-hydroxybenzoate <=> 3-geranyl-4-hydroxybenzoate + diphosphate
|
2.5.1.39
4-hydroxybenzoate polyprenyltransferase
2.5.1.93
4-hydroxybenzoate geranyltransferase
|
–
–
|
|
BRENDA:
BR47433
KEGG:
R05000;
R09040
MetaCyc:
RXN-8920
|
|
|
|
pyruvate + L-aspartate_4-semialdehyde <=> (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O + H+
|
4.3.3.7
4-hydroxy-tetrahydrodipicolinate synthase
|
–
|
|
BRENDA:
BR3399
KEGG:
R10147
MetaCyc:
DIHYDRODIPICSYN-RXN
|
|
|
|
phosphatidylcholine + H2O <=> diacylglycerol + phosphocholine + H+
|
3.1.1.4
phospholipase A2
3.1.4.12
sphingomyelin phosphodiesterase
3.1.4.3
phospholipase C
|
–
–
–
|
|
BRENDA:
BR15957
KEGG:
R01312
MetaCyc:
PHOSPHOLIPASE-C-RXN
SABIO-RK:
1526
|
|
|
|
Nicotine + CO2 + H+ <=> 1-Methylpyrrolinium + nicotinate
|
not assigned
|
–
|
|
KEGG:
R02861
|
|
|
|
L-cysteine + cyanide <=> H+ + Sulfide + Beta-cyanoalanine
|
2.5.1.47
cysteine synthase
2.8.1.1
thiosulfate sulfurtransferase
4.4.1.9
L-3-cyanoalanine synthase
|
–
–
–
|
|
BRENDA:
BR3447
KEGG:
R02846;
R03524
MetaCyc:
L-3-CYANOALANINE-SYNTHASE-RXN
SABIO-RK:
3312;
8566
|
|
|
|
clavaminate <=> Clavulanate-9-aldehyde
|
not assigned
|
–
|
|
KEGG:
R05470
MetaCyc:
RXN-8892
|
|
|
|
N6-acetyl-N6-hydroxy-L-lysine + citrate + ATP <=> N2-citryl-N6-acetyl-N6-hydroxy-L-lysine + AMP + diphosphate + H+
|
6.3.2.38
N2-citryl-N6-acetyl-N6-hydroxylysine synthase
|
–
|
|
KEGG:
R10090
MetaCyc:
RXN-13054
|
|
|
|
2-epi-5-epi-valiolone_7-phosphate <=> 5-epi-valiolone_7-phosphate
|
5.1.3.35
2-epi-5-epi-valiolone 7-phosphate 2-epimerase
|
–
|
|
BRENDA:
BR51426
KEGG:
R11081
MetaCyc:
RXN-16712
|
|
|
|
4-hydroxy-3-methoxyphenyl-beta-hydroxypropionyl-CoA <=> acetyl-CoA + Vanillin
|
4.1.2.41
vanillin synthase
4.1.2.61
feruloyl-CoA hydratase/lyase
|
–
–
|
|
BRENDA:
BR29122
KEGG:
R05773
MetaCyc:
4.1.2.41-RXN
|
|
|
|
enzyme_N6-(dihydrolipoyl)lysine + NAD+ <=> [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine + NADH + H+
|
1.8.1.4
dihydrolipoyl dehydrogenase
|
–
|
|
BRENDA:
BR36970
KEGG:
R03815;
R07618;
R08550
MetaCyc:
1.8.1.4-RXN;
RXN-7716
SABIO-RK:
9140
|
|
|
|
N6-isopentenyladenosine + reduced_flavodoxin + O2 <=> zeatin_riboside + flavin + H2O
|
not assigned
|
–
|
|
KEGG:
R08066
|
|
|
|
taxa-4(20),11-dien-5alpha-ol + acetyl-CoA <=> taxa-4(20),11-dien-5alpha-yl_acetate + CoA
|
2.3.1.162
taxadien-5alpha-ol O-acetyltransferase
|
–
|
|
BRENDA:
BR44011
KEGG:
R06307
MetaCyc:
2.3.1.162-RXN
|
|
|
|
C20821 + pantetheine <=> OA-6129_A
|
not assigned
|
–
|
|
KEGG:
R10749
|
|
|
|
(R)-3-phosphomevalonate + ATP <=> 3,5-diphosphomevalonate + ADP + H+
|
2.7.1.186
mevalonate-3-phosphate 5-kinase
|
–
|
|
BRENDA:
BR51127;
BS427356
KEGG:
R10780
MetaCyc:
RXN-15648
|
|
|
|
abietadienal + reduced_flavodoxin + O2 <=> abietic_acid + flavin + H2O
|
1.14.14.145
abieta-7,13-dien-18-ol hydroxylase
|
–
|
|
BRENDA:
BR52440
KEGG:
R12123
|
|
|
|
amylose <=> maltooligosyltrehalose
|
5.4.99.15
(1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase
|
–
|
|
BRENDA:
BR38
KEGG:
R01824;
R06243
MetaCyc:
5.4.99.15-RXN
|
|
|
|
3-Geranylgeranylindole + O2 + NADPH + H+ <=> 10,11-Epoxy-3-geranylgeranylindole + NADP+ + H2O
|
1.14.13
|
–
|
|
KEGG:
R10350
MetaCyc:
RXN-15495
|
|
|
|
neamine + 5-phospho-alpha-D-ribose_1-diphosphate <=> 5''''-phosphoribostamycin + diphosphate
|
2.4.2.49
neamine phosphoribosyltransferase
|
–
|
|
BRENDA:
BR50426
KEGG:
R08898
MetaCyc:
RXN-13203
|
|
|
|
epigallocatechin + NADP+ <=> delphinidin + NADPH + H+
|
1.3.1.112
anthocyanidin reductase [(2S)-flavan-3-ol-forming]
1.3.1.77
anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]
|
–
–
|
|
BRENDA:
BS373031;
BS426281-a
KEGG:
R06543
MetaCyc:
RXN-9723
|
|
|
|
beta-carotene + reduced_acceptor + O2 <=> echinenone + acceptor + H2O
|
1.14.99.63
beta-carotene 4-ketolase
|
–
|
|
BRENDA:
BR52476
KEGG:
R05345
MetaCyc:
RXN-8184
|
|
|
|
L-tyrosine + O2 + H2O <=> 4-hydroxyphenylacetaldehyde + CO2 + NH3 + H2O2
|
4.1.1.108
4-hydroxyphenylacetaldehyde synthase
|
–
|
|
BRENDA:
BR52268
KEGG:
R11917
MetaCyc:
RXN-19274
|
|
|
|
8-O-methylsterigmatocystin <=> aflatoxin_G1
|
not assigned
|
–
|
|
KEGG:
R10483
MetaCyc:
RXN-9498
|
|
|
|
ATP + diacylglycerol <=> H+ + phosphatidic_acid + ADP
|
2.7.1.107
diacylglycerol kinase (ATP)
2.7.1.138
ceramide kinase
2.7.1.94
acylglycerol kinase
|
–
–
–
|
|
BRENDA:
BR47721
KEGG:
R02240
MetaCyc:
DIACYLGLYKIN-RXN
SABIO-RK:
2211
|
|
|
|
C20913 <=> C20914 + CO2
|
4.1.1
|
–
|
|
KEGG:
R10887
|
|
|
|
L-valine + 2 reduced_flavodoxin + 2 O2 <=> (E/Z)-isobutyraldoxime + 2 flavin + CO2 + 3 H2O
|
1.14.14.38
valine N-monooxygenase
|
–
|
|
BRENDA:
BR49380
KEGG:
R08663
|
|
|
|
acetone_cyanohydrin <=> cyanide + acetone
|
4.1.2.37
hydroxynitrilase
4.1.2.46
aliphatic (R)-hydroxynitrile lyase
4.1.2.47
(S)-hydroxynitrile lyase
|
–
–
–
|
|
BRENDA:
BR368
KEGG:
R01553
MetaCyc:
ACETONE-CYANHYDRIN-LYASE-RXN
SABIO-RK:
1710
|
|
|
|
H+ + 4-coumaroyl-CoA + malonyl-CoA <=> (4-coumaroyl)acetyl-CoA + CoA + CO2
|
2.3.1.218
phenylpropanoylacetyl-CoA synthase
|
–
|
|
BRENDA:
BR50411
KEGG:
R08805
MetaCyc:
RXN-11220
|
|
|
|
Dihydrosanguinarine + reduced_flavodoxin + O2 <=> 10-Hydroxydihydrosanguinarine + flavin + H2O
|
1.14.14.100
dihydrosanguinarine 10-monooxygenase
|
–
|
|
BRENDA:
BR653
KEGG:
R04702
|
|
|
|
feruloyl-CoA <=> 5-hydroxyferuloyl-CoA
|
not assigned
|
–
|
|
KEGG:
R06584
|
|
|
|
S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine <=> phosphatidyl-N,N-dimethylethanolamine + H+ + S-adenosyl-L-homocysteine
|
2.1.1.103
phosphoethanolamine N-methyltransferase
2.1.1.16
methylene-fatty-acyl-phospholipid synthase
2.1.1.17
phosphatidylethanolamine N-methyltransferase
2.1.1.71
phosphatidyl-N-methylethanolamine N-methyltransferase
|
–
–
–
–
|
|
BRENDA:
BR43914
KEGG:
R03424
MetaCyc:
2.1.1.71-RXN
SABIO-RK:
3222
|
|
|
|
S-adenosyl-L-methionine + tetracenomycin_B3 <=> tetracenomycin_B2 + S-adenosyl-L-homocysteine
|
2.1.1
|
–
|
|
KEGG:
R06713
MetaCyc:
RXN-15408
|
|
|
|
5-O-beta-mycaminosyltylonolide + dTDP-6-deoxy-alpha-D-allose <=> demethyllactenocin + dTDP + H+
|
2.4.1.317
O-mycaminosyltylonolide 6-deoxyallosyltransferase
|
–
|
|
BRENDA:
BR50950
KEGG:
R06451
MetaCyc:
RXN-15059
|
|
|
|
3-dimethylallyl-4-hydroxymandelate + O2 <=> 3-dimethylallyl-4-hydroxybenzoate + CO2 + H2O
|
1.13.12.23
4-hydroxy-3-prenylbenzoate synthase
|
–
|
|
BRENDA:
BR52137
KEGG:
R06759
MetaCyc:
RXN-14670
|
|
|
|
neopinone <=> codeinone
|
not assigned
|
–
|
|
KEGG:
R05125
MetaCyc:
RXN-8150
|
|
|
|
(1R,6S)-6-amino-5-oxocyclohex-2-ene-1-carboxylate <=> (1R,5aS,6R)-4a-Hydroxy-1,4,4a,5,5a,6,9,10a-octahydrophenazine-1,6-dicarboxylate + H2O + H+
|
not assigned
|
–
|
|
KEGG:
R11568
MetaCyc:
RXN-17683
|
|
|
|
isocitrate + NADP+ <=> oxalosuccinate + NADPH + H+
|
1.1.1.42
isocitrate dehydrogenase (NADP+)
|
–
|
|
BRENDA:
BS438365
KEGG:
R01899
MetaCyc:
RXN-9951
SABIO-RK:
242
|
|
|
|
N-debenzoyl-(3''-RS)-taxol + benzoyl-CoA <=> H+ + paclitaxel + CoA
|
2.3.1
|
–
|
|
KEGG:
R08171
MetaCyc:
RXN-8859
|
|
|
|
OPC4-CoA + FAD <=> trans-2-Enoyl-OPC4-CoA + FADH2
|
1.3.3.6
acyl-CoA oxidase
|
–
|
|
KEGG:
R07896
|
|
|
|
vitamin_D3 + O2 + reduced_flavodoxin <=> 25-hydroxyvitamin_D3 + flavin + H2O
|
1.14.14.24
vitamin D 25-hydroxylase
|
–
|
|
BRENDA:
BR50107
KEGG:
R03611
|
|
|
|
(S)-4-hydroxymandelonitrile <=> 4-hydroxybenzaldehyde + cyanide
|
4.1.2.11
hydroxymandelonitrile lyase
4.1.2.47
(S)-hydroxynitrile lyase
|
–
–
|
|
BRENDA:
BR342
KEGG:
R02676
MetaCyc:
HYDROXYMANDELONITRILE-LYASE-RXN
|
|
|
|
echinenone <=> canthaxanthin
|
not assigned
|
–
|
|
KEGG:
R12180
|
|
|
|
ADP-glucose + H2O <=> AMP + alpha-D-glucose_1-phosphate + H+
|
3.6.1.13
ADP-ribose diphosphatase
3.6.1.21
ADP-sugar diphosphatase
3.6.1.45
UDP-sugar diphosphatase
3.6.1.9
nucleotide diphosphatase
|
–
–
–
–
|
|
BRENDA:
BS141208;
BS141270
KEGG:
R00951
MetaCyc:
RXN-10770
SABIO-RK:
1264;
8816
|
|
|
|
S-adenosyl-L-methionine + a_bacteriochlorophyllide_c + H2O <=> bacteriochlorophyllide_e + 5''-deoxyadenosine + L-methionine + H+
|
1.17.98.2
bacteriochlorophyllide c C-71-hydroxylase
|
–
|
|
BRENDA:
BR51842
KEGG:
R11710
MetaCyc:
RXN-18413
|
|
|
|
3-Dehydroteasterone <=> typhasterol
|
not assigned
|
–
|
|
KEGG:
R07469
|
|
|
|
sparteine <=> Cytisine
|
not assigned
|
–
|
|
KEGG:
R08420
|
|
|
|
N,N'-bis(7-[[(2R,3R,4S,5R)-3,4-dihydroxy-5-methoxy-6,6-dimethyltetrahydro-2H-pyran-2-yl]oxy]-4-hydroxy-8-methyl-2-oxo-2H-chromen-3-yl)-3-methyl-1H-pyrrole-2,4-dicarboxamide + 2 (1H-pyrrole-2-carbonyl)-[peptidyl-carrier_protein] <=> coumermycin
|
not assigned
|
–
|
|
KEGG:
R06768
|
|
|
|
ent-isokauren-2beta-ol + O2 + reduced_flavodoxin <=> ent-isokaurene-2beta,3beta-diol + flavin + H2O
|
1.14.14.76
ent-isokaurene C2/C3-hydroxylase
|
–
|
|
BRENDA:
BR52395
KEGG:
R11978
|
|
|
|
S-adenosyl-L-methionine + gamma-tocopherol <=> S-adenosyl-L-homocysteine + alpha-tocopherol + H+
|
2.1.1.95
tocopherol C-methyltransferase
|
–
|
|
BRENDA:
BR43934
KEGG:
R07236
MetaCyc:
TOCOPHEROL-O-METHYLTRANSFERASE-RXN
|
|
|
|
(13E)-8alpha-hydroxylabd-13-en-15-yl_diphosphate <=> cis-abienol + diphosphate
|
4.2.3.140
cis-abienol synthase
|
–
|
|
BRENDA:
BR50337
KEGG:
R10276
MetaCyc:
RXN-13770
|
|
|
|
1,2-dihydrovomilenine + NADP+ <=> Vomilenine + NADPH + H+
|
1.5.1.32
vomilenine reductase
|
–
|
|
BRENDA:
BR40354
KEGG:
R05878
MetaCyc:
1.5.1.32-RXN
|
|
|
|
apigenin + reduced_flavodoxin + O2 <=> luteolin + flavin + H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
1.14.14.82
flavonoid 3'-monooxygenase
|
–
–
|
|
BRENDA:
BS288545
KEGG:
R06537
|
|
|
|
dTDP-6-deoxy-alpha-D-allose + NAD+ <=> dTDP-4-dehydro-6-deoxy-alpha-D-gulose + NADH + H+
|
1.1.1.364
dTDP-4-dehydro-6-deoxy-alpha-D-gulose 4-ketoreductase
|
–
|
|
BRENDA:
BR50819-a
KEGG:
R06438
MetaCyc:
RXN-15048_WOP
|
|
|
|
tetracenomycin_D3 <=> tetracenomycin_B3
|
not assigned
|
–
|
|
KEGG:
R06701
|
|
|
|
3-Hydroxy-OPC4-CoA <=> trans-2-Enoyl-OPC4-CoA + H2O
|
4.2.1.17
enoyl-CoA hydratase
4.2.1.74
long-chain-enoyl-CoA hydratase
|
–
–
|
|
KEGG:
R07897
|
|
|
|
S-adenosyl-L-methionine + 7-methylxanthine <=> H+ + Theobromine + S-adenosyl-L-homocysteine
|
2.1.1.159
theobromine synthase
2.1.1.160
caffeine synthase
|
–
–
|
|
BRENDA:
BR48813
KEGG:
R07919
MetaCyc:
RXN-7598
SABIO-RK:
14237
|
|
|
|
indole-3-glycerol_phosphate <=> indole + D-glyceraldehyde_3-phosphate
|
4.1.2.8
indole-3-glycerol-phosphate lyase
4.2.1.20
tryptophan synthase
|
–
–
|
|
BRENDA:
BR48765;
BS368282;
BS383209
KEGG:
R02340
MetaCyc:
RXN0-2381
SABIO-RK:
9527
|
|
|
|
dimethylallyl_diphosphate <=> isoprene + diphosphate
|
4.2.3.27
isoprene synthase
|
–
|
|
BRENDA:
BR48809
KEGG:
R08199
MetaCyc:
4.2.3.27-RXN
|
|
|
|
kanosamine_6-phosphate + H2O <=> kanosamine + phosphate
|
3.1.3.92
kanosamine-6-phosphate phosphatase
|
–
|
|
BRENDA:
BR50762
KEGG:
R10547
MetaCyc:
RXN8J2-138
|
|
|
|
2-amino-4,5-dihydroxy-6-oxo-7-(phosphonooxy)heptanoate <=> H+ + 3-Amino-4-hydroxybenzoic_acid + phosphate + H2O
|
4.1.99.20
3-amino-4-hydroxybenzoate synthase
|
–
|
|
BRENDA:
BR50715
KEGG:
R10469
MetaCyc:
RXN-13866
SABIO-RK:
12674
|
|
|
|
3,5,7,9,11,13,15,17,19-Nonaoxo-eicosanoyl-[acp] <=> 9,14-Decaketide_intermediate_1 + 2 H2O
|
2.3.1.235
tetracenomycin F2 synthase
4.2.1
|
–
–
|
|
KEGG:
R09269
|
|
|
|
(S)-4-(3''-acetyl-5''-hydroxy-4''-oxo-1,4''-dihydronapthalen-2''-yl)-3-hydroxybutanoate <=> 2-((1R,3S),-1,9''-dihydroxy-1''-methyl-10''-oxo-3,4,5,10''-tetrahydro-1H-benzo[g]isochromen-3''-yl)acetate
|
5.5.1
|
–
|
|
KEGG:
R09307
MetaCyc:
RXN1A0-6312
|
|
|
|
dTDP-6-deoxy-beta-L-talose + NAD+ <=> dTDP-4-dehydro-beta-L-rhamnose + NADH + H+
|
1.1.1.339
dTDP-6-deoxy-L-talose 4-dehydrogenase (NAD+)
1.1.1.344
dTDP-6-deoxy-L-talose 4-dehydrogenase [NAD(P)+]
|
–
–
|
|
BRENDA:
BR49657-a
KEGG:
R10190
MetaCyc:
RXN-13749;
RXN-14184_WOP
|
|
|
|
(2E,6E)-farnesyl_diphosphate <=> (E)-beta-caryophyllene + diphosphate
|
4.2.3.57
(-)-beta-caryophyllene synthase
4.2.3.89
(+)-beta-caryophyllene synthase
|
–
–
|
|
BRENDA:
BR49428
KEGG:
R08541
MetaCyc:
RXN-8414
|
|
|
|
H+ + cannabidiolate <=> cannabidiol + CO2
|
not assigned
|
–
|
|
KEGG:
R12103
MetaCyc:
RXN-7858
|
|
|
|
isopimara-7,15-diene <=> isopimara-7,15-dienol
|
1.14.13
|
–
|
|
KEGG:
R09112
|
|
|
|
naringenin + 2-oxoglutarate + O2 <=> apigenin + succinate + CO2 + H2O + H+
|
1.14.20.4
anthocyanidin synthase
1.14.20.5
flavone synthase I
|
–
–
|
|
BRENDA:
BS371268
KEGG:
R02445
MetaCyc:
RXN-7686
|
|
|
|
hexadecanal <=> alkane + CO
|
4.1.99.5
aldehyde oxygenase (deformylating)
|
–
|
|
KEGG:
R09466
|
|
|
|
paraxanthine + NADH + O2 + H+ <=> 7-methylxanthine + NAD+ + formaldehyde + H2O
|
1.14.13.128
7-methylxanthine demethylase
1.14.13.178
methylxanthine N1-demethylase
|
–
–
|
|
BRENDA:
BR50579-a
KEGG:
R07957
MetaCyc:
RXN-11517_WOP
|
|
|
|
7-hydroxy-2,4,5''-trimethoxyisoflavone <=> 9-Demethylmunduserone
|
not assigned
|
–
|
|
KEGG:
R07736
MetaCyc:
RXN-9057
|
|
|
|
H+ + H2O + L-pyrroline-5-carboxylate <=> L-glutamate_5-semialdehyde
|
0.0.0.0
|
–
|
|
BRENDA:
BR52883
KEGG:
R03314
MetaCyc:
SPONTPRO-RXN
|
|
|
|
1,3-dihydroxy-N-methylacridone <=> Rutacridone
|
not assigned
|
–
|
|
KEGG:
R08472
|
|
|
|
paromamine + UDP-D-xylose <=> gentamicin_A2 + UDP + H+
|
2.4.2
|
–
|
|
KEGG:
R11289
MetaCyc:
RXN-13232
|
|
|
|
L-serine + L-homocysteine <=> L-cystathionine + H2O
|
2.5.1.47
cysteine synthase
4.2.1.22
cystathionine beta-synthase
|
–
–
|
|
BRENDA:
BR406
KEGG:
R01289;
R01290
MetaCyc:
CYSTATHIONINE-BETA-SYNTHASE-RXN
SABIO-RK:
1504;
1505
|
|
|
|
geranyl_diphosphate <=> (+)-limonene + diphosphate
|
4.2.3.20
(R)-limonene synthase
|
–
|
|
BRENDA:
BR47586
KEGG:
R06120
MetaCyc:
4.2.3.20-RXN
|
|
|
|
5-phosphoribosylamine + ATP + glycine <=> H+ + ADP + phosphate + beta-glycinamide_ribonucleotide
|
6.3.4.13
phosphoribosylamine---glycine ligase
|
–
|
|
BRENDA:
BR134
KEGG:
R04144
MetaCyc:
GLYRIBONUCSYN-RXN
|
|
|
|
2,5,7,4'-tetrahydroxyisoflavanone <=> genistein + H2O + H+
|
4.2.1.105
2-hydroxyisoflavanone dehydratase
|
–
|
|
BRENDA:
BR50563
KEGG:
R06793
MetaCyc:
RXN-3303
SABIO-RK:
10560
|
|
|
|
myo-inositol + NAD+ <=> scyllo-inosose + NADH + H+
|
1.1.1.114
apiose 1-reductase
1.1.1.18
inositol 2-dehydrogenase
|
–
–
|
|
BRENDA:
BR36703;
BS187060
KEGG:
R01183
MetaCyc:
MYO-INOSITOL-2-DEHYDROGENASE-RXN
SABIO-RK:
1420
|
|
|
|
fumigaclavine_B + acetyl-CoA <=> fumigaclavine_A + CoA
|
2.3.1.205
fumigaclavine B O-acetyltransferase
|
–
|
|
BRENDA:
BR50283
KEGG:
R10200
MetaCyc:
RXN-11366
|
|
|
|
valienone + ATP <=> H+ + valienone_7-phosphate + ADP
|
2.7.1.214
C7-cyclitol 7-kinase
|
–
|
|
BRENDA:
BR51758
KEGG:
R11234
MetaCyc:
RXN-9144
|
|
|
|
dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose + 2-oxoglutarate <=> dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose + L-glutamate
|
2.6.1.89
dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose transaminase
|
–
|
|
BRENDA:
BR49899
KEGG:
R06423
MetaCyc:
RXN-12810
|
|
|
|
(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD+ + H2O <=> (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NADH + H+
|
1.17.1.8
4-hydroxy-tetrahydrodipicolinate reductase
|
–
|
|
BRENDA:
BR36807-a
KEGG:
R04198
MetaCyc:
RXN-14014_WOP
|
|
|
|
7,9,12-Decaketide_intermediate_5 <=> 7,9,12-Decaketide_intermediate_6 + 2 H2O
|
4.2.1
|
–
|
|
KEGG:
R09267
|
|
|
|
(2S)-2-amino-4-deoxy-chorismate + H2O <=> (5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxylic_acid + pyruvate
|
3.3.2.15
trans-2,3-dihydro-3-hydroxyanthranilic acid synthase
3.3.2.B1
|
–
–
|
|
BRENDA:
BR49262
KEGG:
R11463
MetaCyc:
RXN-9030
|
|
|
|
(-)-trans-carveol + NADP+ <=> (-)-Carvone + NADPH + H+
|
1.1.1.243
carveol dehydrogenase
1.3.1.102
2-alkenal reductase (NADP+)
|
–
–
|
|
BRENDA:
BR29279
KEGG:
R03114
MetaCyc:
CARVEOL-DEHYDROGENASE-RXN
SABIO-RK:
2951
|
|
|
|
Megalomicin_A <=> Megalomicin_C1
|
not assigned
|
–
|
|
KEGG:
R06504
|
|
|
|
phosphatidylcholine + H2O <=> 2-acylglycerophosphocholine |