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(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
(3R)-hydroxybutyryl-CoA + NADP+ <=> acetoacetyl-CoA + NADPH + H+ 3-oxoacyl-[acyl-carrier-protein] reductase 3-hydroxybutyryl-CoA dehydrogenase acetoacetyl-CoA reductase

(3R)-hydroxybutyryl-CoA + H2O <=> (R)-3-hydroxybutanoate + CoA + H+ palmitoyl-CoA hydrolase acyl-CoA hydrolase 3-hydroxyisobutyryl-CoA hydrolase

(S)-3-hydroxybutyryl-CoA + NAD+ <=> acetoacetyl-CoA + NADH + H+ 3-hydroxy-2-methylbutyryl-CoA dehydrogenase 3-hydroxyacyl-CoA dehydrogenase acetoacetyl-CoA reductase

(S)-3-hydroxybutyryl-CoA + H2O <=> L-3-hydroxybutyrate + CoA + H+ 3-hydroxyisobutyryl-CoA hydrolase

acetyl-CoA <=> acetoacetyl-CoA + CoA hydroxymethylglutaryl-CoA reductase (NADPH) acetyl-CoA C-myristoyltransferase acetyl-CoA C-acyltransferase [acyl-carrier-protein] S-acetyltransferase acetyl-CoA C-acetyltransferase

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